SPC25 (SPC25 component of NDC80 kinetochore complex)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 57405 |
| Gene name | SPC25 component of NDC80 kinetochore complex |
| Gene symbol | SPC25 |
| Synonyms (NCBI Gene) |
AD024SPBC25hSpc25
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| Chromosome | 2 |
| Chromosome location | 2q24.3 |
| Summary | This gene encodes a protein that may be involved in kinetochore-microtubule interaction and spindle checkpoint activity. [provided by RefSeq, Jul 2008] |
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miRNA
miRNA information provided by mirtarbase database.
531
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
22
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9HBM1 | ||||||||||
| Protein name | Kinetochore protein Spc25 (hSpc25) | ||||||||||
| Protein function | Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:14699129, PubMed:14738735). Required for kinetochore integrity and the organization o | ||||||||||
| PDB | 2VE7 , 3IZ0 , 8PPR , 8Q5H | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 224 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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