Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
5738
Gene name Gene Name - the full gene name approved by the HGNC.
Prostaglandin F2 receptor inhibitor
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
PTGFRN
Synonyms (NCBI Gene) Gene synonyms aliases
CD315, CD9P-1, EWI-F, FPRP, SMAP-6
Chromosome Chromosome number
1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1p13.1
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT005149 hsa-miR-30a-5p pSILAC 18668040
MIRT005149 hsa-miR-30a-5p Proteomics;Other 18668040
MIRT030461 hsa-miR-24-3p Sequencing 20371350
MIRT051989 hsa-let-7b-5p CLASH 23622248
MIRT049140 hsa-miR-92a-3p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 11278880, 23091066, 23289620, 26686862, 30833792
GO:0005789 Component Endoplasmic reticulum membrane IEA
GO:0005794 Component Golgi apparatus IEA
GO:0009986 Component Cell surface HDA 19581412
GO:0014905 Process Myoblast fusion involved in skeletal muscle regeneration ISS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
601204 9601 ENSG00000134247
Protein
UniProt ID Q9P2B2
Protein name Prostaglandin F2 receptor negative regulator (CD9 partner 1) (CD9P-1) (Glu-Trp-Ile EWI motif-containing protein F) (EWI-F) (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD antigen CD315)
Protein function Inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur (By similar
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07686 V-set 26 141 Immunoglobulin V-set domain Domain
PF07686 V-set 282 391 Immunoglobulin V-set domain Domain
Sequence
MGRLASRPLLLALLSLALCRGRVVRVPTATLVRVVGTELVIPCNVSDYDGPSEQNFDWSF
SSLGSSFVELASTWEVGFPAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCS
TPSTDATVQGNYEDTVQVKVL
ADSLHVGPSARPPPSLSLREGEPFELRCTAASASPLHTH
LALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSA
DQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVLRAAVPKNVSVAEGKELDLTCN
ITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSPHVALSHVDARSYHLLV
RDVSKENSGYYYCHVSLWAPGHNRSWHKVAE
AVSSPAGVGVTWLEPDYQVYLNASKVPGF
ADDPTELACRVVDTKSGEANVRFTVSWYYRMNRRSDNVVTSELLAVMDGDWTLKYGERSK
QRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSWVKSKDVFSKPVN
IFWALEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKSPRYSVLIMAEKPVGDLSSPN
ETKYIISLDQDSVVKLENWTDASRVDGVVLEKVQEDEFRYRMYQTQVSDAGLYRCMVTAW
SPVRGSLWREAATSLSNPIEIDFQTSGPIFNASVHSDTPSVIRGDLIKLFCIITVEGAAL
DPDDMAFDVSWFAVHSFGLDKAPVLLSSLDRKGIVTTSRRDWKSDLSLERVSVLEFLLQV
HGSEDQDFGNYYCSVTPWVKSPTGSWQKEAEIHSKPVFITVKMDVLNAFKYPLLIGVGLS
TVIGLLSCLIGYCSSHWCCKKEVQETRRERRRLMSMEMD
Sequence length 879
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Diabetes mellitus Diabetes Mellitus, Non-Insulin-Dependent rs587776515, rs61730328, rs606231121, rs606231122, rs79020217, rs77625743, rs78378398, rs606231123, rs1362648752, rs104893649, rs80356624, rs80356616, rs80356625, rs80356611, rs104894237
View all (293 more)
30054458
Prostate cancer Prostate carcinoma rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 20932654
Unknown
Disease term Disease name Evidence References Source
Diabetes Diabetes GWAS
Multiple Sclerosis Multiple Sclerosis GWAS
Tremor Tremor GWAS
Associations from Text Mining
Disease Name Relationship Type References
AA amyloidosis Associate 32854315
Alzheimer Disease Associate 32854315
Cognitive Dysfunction Associate 32854315
Coronary Artery Disease Associate 33009702
Glioma Associate 35488675
Melanoma Associate 35606887
Neoplasm Metastasis Associate 35488675
Neoplasms Associate 35488675, 35606887
Teratoma Associate 36289533