PTGFR (prostaglandin F receptor)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 5737 |
| Gene name | Prostaglandin F receptor |
| Gene symbol | PTGFR |
| Synonyms (NCBI Gene) |
FP
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| Chromosome | 1 |
| Chromosome location | 1p31.1 |
| Summary | The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pre |
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SNPs
SNP information provided by dbSNP.
1
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miRNA
miRNA information provided by mirtarbase database.
437
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Transcription factors
Transcription factors information provided by TRRUST V2 database.
3
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
26
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P43088 | ||||||||||
| Protein name | Prostaglandin F2-alpha receptor (PGF receptor) (PGF2-alpha receptor) (Prostanoid FP receptor) | ||||||||||
| Protein function | Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum (By similarity). Isoforms | ||||||||||
| PDB | 8IQ4 , 8IQ6 , 8IUK , 8IUL , 8IUM , 8XJK , 8XJL , 8XJM | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Eye. {ECO:0000269|PubMed:18587449}. | ||||||||||
| Sequence |
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| Sequence length | 359 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
1
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