ATP8B2 (ATPase phospholipid transporting 8B2)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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57198 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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ATPase phospholipid transporting 8B2 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ATP8B2 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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ATPID |
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Chromosome
Chromosome number
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1 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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1q21.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from on |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||||||||||||
| UniProt ID | P98198 | ||||||||||||||||||||
| Protein name | Phospholipid-transporting ATPase ID (EC 7.6.2.1) (ATPase class I type 8B member 2) (P4-ATPase flippase complex alpha subunit ATP8B2) | ||||||||||||||||||||
| Protein function | Catalytic component of P4-ATPase flippase complex, which catalyzes the hydrolysis of ATP coupled to the transport of phosphatidylcholine (PC) from the outer to the inner leaflet of the plasma membrane. May contribute to the maintenance of membra | ||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Isoform 3 is ubiquitous, with highest expression in aorta, cerebellum and uterus. {ECO:0000269|PubMed:12880872}. | ||||||||||||||||||||
| Sequence |
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| Sequence length | 1209 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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