Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein
Entrez ID	57140
Gene name	Arginyl aminopeptidase like 1
Gene symbol	RNPEPL1
Synonyms (NCBI Gene)	-
Chromosome	2
Chromosome location	2q37.3

109

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miRTarBase ID	miRNA	Experiments	Reference
MIRT002699	hsa-miR-124-3p	Microarray	15685193
MIRT002699	hsa-miR-124-3p	Microarray	18668037
MIRT002699	hsa-miR-124-3p	Microarray	15685193
MIRT724346	hsa-miR-4308	HITS-CLIP	19536157
MIRT724345	hsa-miR-4292	HITS-CLIP	19536157
MIRT724344	hsa-miR-6791-5p	HITS-CLIP	19536157
MIRT724343	hsa-miR-339-5p	HITS-CLIP	19536157
MIRT724342	hsa-miR-939-3p	HITS-CLIP	19536157
MIRT724341	hsa-miR-6852-5p	HITS-CLIP	19536157
MIRT724340	hsa-miR-6742-3p	HITS-CLIP	19536157
MIRT724339	hsa-miR-1266-3p	HITS-CLIP	19536157
MIRT724338	hsa-miR-7113-3p	HITS-CLIP	19536157
MIRT724337	hsa-miR-26b-3p	HITS-CLIP	19536157
MIRT724336	hsa-miR-3199	HITS-CLIP	19536157
MIRT724335	hsa-miR-8052	HITS-CLIP	19536157
MIRT724334	hsa-miR-365a-5p	HITS-CLIP	19536157
MIRT724333	hsa-miR-365b-5p	HITS-CLIP	19536157
MIRT724332	hsa-miR-1343-3p	HITS-CLIP	19536157
MIRT724331	hsa-miR-6783-3p	HITS-CLIP	19536157
MIRT724346	hsa-miR-4308	HITS-CLIP	19536157
MIRT724345	hsa-miR-4292	HITS-CLIP	19536157
MIRT724344	hsa-miR-6791-5p	HITS-CLIP	19536157
MIRT724343	hsa-miR-339-5p	HITS-CLIP	19536157
MIRT724342	hsa-miR-939-3p	HITS-CLIP	19536157
MIRT724341	hsa-miR-6852-5p	HITS-CLIP	19536157
MIRT724340	hsa-miR-6742-3p	HITS-CLIP	19536157
MIRT724339	hsa-miR-1266-3p	HITS-CLIP	19536157
MIRT724338	hsa-miR-7113-3p	HITS-CLIP	19536157
MIRT724337	hsa-miR-26b-3p	HITS-CLIP	19536157
MIRT724336	hsa-miR-3199	HITS-CLIP	19536157
MIRT724335	hsa-miR-8052	HITS-CLIP	19536157
MIRT724334	hsa-miR-365a-5p	HITS-CLIP	19536157
MIRT724333	hsa-miR-365b-5p	HITS-CLIP	19536157
MIRT724332	hsa-miR-1343-3p	HITS-CLIP	19536157
MIRT724331	hsa-miR-6783-3p	HITS-CLIP	19536157
MIRT1314370	hsa-miR-1205	CLIP-seq
MIRT1314371	hsa-miR-1254	CLIP-seq
MIRT1314372	hsa-miR-1343	CLIP-seq
MIRT1314373	hsa-miR-1909	CLIP-seq
MIRT1314374	hsa-miR-296-5p	CLIP-seq
MIRT1314375	hsa-miR-3116	CLIP-seq
MIRT1314376	hsa-miR-3155	CLIP-seq
MIRT1314377	hsa-miR-3155b	CLIP-seq
MIRT1314378	hsa-miR-3176	CLIP-seq
MIRT1314379	hsa-miR-3184	CLIP-seq
MIRT1314380	hsa-miR-3922-3p	CLIP-seq
MIRT1314381	hsa-miR-423-5p	CLIP-seq
MIRT1314382	hsa-miR-4287	CLIP-seq
MIRT1314383	hsa-miR-4423-5p	CLIP-seq
MIRT1314384	hsa-miR-4469	CLIP-seq
MIRT1314385	hsa-miR-4489	CLIP-seq
MIRT1314386	hsa-miR-4640-5p	CLIP-seq
MIRT1314387	hsa-miR-4685-3p	CLIP-seq
MIRT1314388	hsa-miR-4726-5p	CLIP-seq
MIRT1314389	hsa-miR-484	CLIP-seq
MIRT1314390	hsa-miR-661	CLIP-seq
MIRT1314391	hsa-miR-760	CLIP-seq
MIRT2093526	hsa-miR-1226	CLIP-seq
MIRT1314371	hsa-miR-1254	CLIP-seq
MIRT2093527	hsa-miR-147b	CLIP-seq
MIRT2093528	hsa-miR-1915	CLIP-seq
MIRT2093529	hsa-miR-2861	CLIP-seq
MIRT2093530	hsa-miR-29a	CLIP-seq
MIRT2093531	hsa-miR-29b	CLIP-seq
MIRT2093532	hsa-miR-29c	CLIP-seq
MIRT2093533	hsa-miR-3065-3p	CLIP-seq
MIRT1314375	hsa-miR-3116	CLIP-seq
MIRT2093534	hsa-miR-3156-3p	CLIP-seq
MIRT1314379	hsa-miR-3184	CLIP-seq
MIRT2093535	hsa-miR-3192	CLIP-seq
MIRT2093536	hsa-miR-3657	CLIP-seq
MIRT1314381	hsa-miR-423-5p	CLIP-seq
MIRT2093537	hsa-miR-4301	CLIP-seq
MIRT1314383	hsa-miR-4423-5p	CLIP-seq
MIRT2093538	hsa-miR-4457	CLIP-seq
MIRT1314385	hsa-miR-4489	CLIP-seq
MIRT1314386	hsa-miR-4640-5p	CLIP-seq
MIRT2093539	hsa-miR-4669	CLIP-seq
MIRT1314388	hsa-miR-4726-5p	CLIP-seq
MIRT2093540	hsa-miR-4727-5p	CLIP-seq
MIRT2093541	hsa-miR-4728-5p	CLIP-seq
MIRT2093542	hsa-miR-4731-3p	CLIP-seq
MIRT2093543	hsa-miR-4769-3p	CLIP-seq
MIRT2093544	hsa-miR-4801	CLIP-seq
MIRT2093545	hsa-miR-532-3p	CLIP-seq
MIRT2093546	hsa-miR-593	CLIP-seq
MIRT2093547	hsa-miR-634	CLIP-seq
MIRT1314390	hsa-miR-661	CLIP-seq
MIRT2318074	hsa-miR-1231	CLIP-seq
MIRT2318075	hsa-miR-124	CLIP-seq
MIRT2318076	hsa-miR-1913	CLIP-seq
MIRT2093535	hsa-miR-3192	CLIP-seq
MIRT2318077	hsa-miR-324-3p	CLIP-seq
MIRT2318078	hsa-miR-331-3p	CLIP-seq
MIRT2093536	hsa-miR-3657	CLIP-seq
MIRT2318079	hsa-miR-3689a-3p	CLIP-seq
MIRT2318080	hsa-miR-3689c	CLIP-seq
MIRT2318081	hsa-miR-4258	CLIP-seq
MIRT1314382	hsa-miR-4287	CLIP-seq
MIRT2318082	hsa-miR-4313	CLIP-seq
MIRT2318083	hsa-miR-4314	CLIP-seq
MIRT1314384	hsa-miR-4469	CLIP-seq
MIRT2318084	hsa-miR-4646-5p	CLIP-seq
MIRT2093539	hsa-miR-4669	CLIP-seq
MIRT1314387	hsa-miR-4685-3p	CLIP-seq
MIRT2318085	hsa-miR-4690-3p	CLIP-seq
MIRT2318086	hsa-miR-4707-3p	CLIP-seq
MIRT2093541	hsa-miR-4728-5p	CLIP-seq
MIRT2318087	hsa-miR-506	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0004177	Function	Aminopeptidase activity	IEA
GO:0004239	Function	Initiator methionyl aminopeptidase activity	IEA
GO:0006508	Process	Proteolysis	IBA
GO:0006508	Process	Proteolysis	IDA	11017071
GO:0006508	Process	Proteolysis	IEA
GO:0008233	Function	Peptidase activity	IEA
GO:0008237	Function	Metallopeptidase activity	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0070006	Function	Metalloaminopeptidase activity	IBA
GO:0070006	Function	Metalloaminopeptidase activity	IDA	11017071
GO:0070006	Function	Metalloaminopeptidase activity	IEA

MIM	HGNC	e!Ensembl
605287	10079	ENSG00000142327

Q9HAU8

Protein name

Aminopeptidase RNPEPL1 (EC 3.4.11.-) (Arginyl aminopeptidase-like 1) (Methionyl aminopeptidase) (EC 3.4.11.18)

Protein function

Broad specificity aminopeptidase which preferentially hydrolyzes an N-terminal methionine, citrulline or glutamine.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF17900	Peptidase_M1_N	133 → 258		Domain
PF01433	Peptidase_M1	291 → 501	Peptidase family M1 domain	Domain
PF09127	Leuk-A4-hydro_C	560 → 673	Leukotriene A4 hydrolase, C-terminal	Family

Tissue specificity

TISSUE SPECIFICITY: Ubiquitously expressed. Expressed at relatively higher levels in heart and skeletal muscle. {ECO:0000269|PubMed:11017071, ECO:0000269|PubMed:19508204}.

Sequence

MAAQCCCRQAPGAEAAPVRPPPEPPPALDVASASSAQLFRLRHLQLGLELRPEARELAGC
LVLELCALRPAPRALVLDAHPALRLHSAAFRRAPAAAAETPCAFAFSAPGPGPAPPPPLP
AFPEAPGSEPACCPLAFRVDPFTDYGSSLTVTLPPELQAHQPFQVILRYTSTDAPAIWWL
DPELTYGCAKPFVFTQGHSVCNRSFFPCFDTPAVKCTYSAVVKAPSGVQVLMSATRSAYM
EEEGVFHFHMEHPVPAYLVALVAGDLKPADIGPRSRVWAEPCLLPTATSKLSGAVEQWLS
AAERLYGPYMWGRYDIVFLPPSFPIVAMENPCLTFIISSILESDEFLVIDVIHEVAHSWF
GNAVTNATWEEMWLSEGLATYAQRRITTETYGAAFTCLETAFRLDALHRQMKLLGEDSPV
SKLQVKLEPGVNPSHLMNLFTYEKGYCFVYYLSQLCGDPQRFDDFLRAYVEKYKFTSVVA
QDLLDSFLSFFPELKEQSVDCRAGLEFERWLNATGPPLAEPDLSQGSSLTRPVEALFQLW
TAEPLDQAAASASAIDISKWRTFQTALFLDRLLDGSPLPQEVVMSLSKCYSSLLDSMNAE
IRIRWLQIVVRNDYYPDLHRVRRFLESQMSRMYTIPLYEDLCTGALKSFALEVFYQTQGR
LHPNLRRAIQQILSQGLGSSTEPASEPSTELGKAEADTDSDAQALLLGDEAPSSAISLRD
VNVSA

Sequence length

725

Interactions

View interactions

RNPEPL1 (arginyl aminopeptidase like 1)