MAN1C1 (mannosidase alpha class 1C member 1)

Gene

• Entrez ID: 57134
• Gene name: Mannosidase alpha class 1C member 1
• Gene symbol: MAN1C1
• Synonyms (NCBI Gene): HMIC, MAN1A3, MAN1C, pp6318
• Chromosome: 1
• Chromosome location: 1p36.11

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT020204	hsa-miR-130b-3p	Sequencing	20371350
MIRT028164	hsa-miR-93-5p	Sequencing	20371350
MIRT050567	hsa-miR-20a-5p	CLASH	23622248
MIRT623327	hsa-miR-552-3p	HITS-CLIP	19536157
MIRT709826	hsa-miR-6871-5p	HITS-CLIP	19536157
MIRT628027	hsa-miR-6769a-5p	HITS-CLIP	19536157
MIRT628026	hsa-miR-6769b-5p	HITS-CLIP	19536157
MIRT623327	hsa-miR-552-3p	HITS-CLIP	19536157
MIRT709826	hsa-miR-6871-5p	HITS-CLIP	19536157
MIRT628027	hsa-miR-6769a-5p	HITS-CLIP	19536157
MIRT628026	hsa-miR-6769b-5p	HITS-CLIP	19536157
MIRT623327	hsa-miR-552-3p	HITS-CLIP	19536157
MIRT709826	hsa-miR-6871-5p	HITS-CLIP	19536157
MIRT628027	hsa-miR-6769a-5p	HITS-CLIP	19536157
MIRT628026	hsa-miR-6769b-5p	HITS-CLIP	19536157
MIRT623327	hsa-miR-552-3p	HITS-CLIP	19536157
MIRT709826	hsa-miR-6871-5p	HITS-CLIP	19536157
MIRT628027	hsa-miR-6769a-5p	HITS-CLIP	19536157
MIRT628026	hsa-miR-6769b-5p	HITS-CLIP	19536157
MIRT623327	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT623326	hsa-miR-3663-3p	HITS-CLIP	23824327
MIRT623325	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT628027	hsa-miR-6769a-5p	HITS-CLIP	23824327
MIRT628026	hsa-miR-6769b-5p	HITS-CLIP	23824327
MIRT623324	hsa-miR-8055	HITS-CLIP	23824327
MIRT628025	hsa-miR-6885-3p	HITS-CLIP	23824327
MIRT623323	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT623327	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT623326	hsa-miR-3663-3p	HITS-CLIP	23824327
MIRT623325	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT628027	hsa-miR-6769a-5p	HITS-CLIP	23824327
MIRT628026	hsa-miR-6769b-5p	HITS-CLIP	23824327
MIRT623324	hsa-miR-8055	HITS-CLIP	23824327
MIRT628025	hsa-miR-6885-3p	HITS-CLIP	23824327
MIRT623327	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT623326	hsa-miR-3663-3p	HITS-CLIP	23824327
MIRT623325	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT623324	hsa-miR-8055	HITS-CLIP	23824327
MIRT623323	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT623323	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT623323	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT623326	hsa-miR-3663-3p	HITS-CLIP	27418678
MIRT623326	hsa-miR-3663-3p	HITS-CLIP	27418678
MIRT623327	hsa-miR-552-3p	HITS-CLIP	27418678
MIRT623327	hsa-miR-552-3p	HITS-CLIP	27418678
MIRT628027	hsa-miR-6769a-5p	HITS-CLIP	27418678
MIRT628026	hsa-miR-6769b-5p	HITS-CLIP	27418678
MIRT623324	hsa-miR-8055	HITS-CLIP	27418678
MIRT623324	hsa-miR-8055	HITS-CLIP	27418678
MIRT623327	hsa-miR-552-3p	HITS-CLIP	19536157
MIRT709826	hsa-miR-6871-5p	HITS-CLIP	19536157
MIRT628027	hsa-miR-6769a-5p	HITS-CLIP	19536157
MIRT628026	hsa-miR-6769b-5p	HITS-CLIP	19536157
MIRT623327	hsa-miR-552-3p	HITS-CLIP	19536157
MIRT709826	hsa-miR-6871-5p	HITS-CLIP	19536157
MIRT628027	hsa-miR-6769a-5p	HITS-CLIP	19536157
MIRT628026	hsa-miR-6769b-5p	HITS-CLIP	19536157
MIRT623327	hsa-miR-552-3p	HITS-CLIP	19536157
MIRT709826	hsa-miR-6871-5p	HITS-CLIP	19536157
MIRT628027	hsa-miR-6769a-5p	HITS-CLIP	19536157
MIRT628026	hsa-miR-6769b-5p	HITS-CLIP	19536157
MIRT623327	hsa-miR-552-3p	HITS-CLIP	19536157
MIRT709826	hsa-miR-6871-5p	HITS-CLIP	19536157
MIRT628027	hsa-miR-6769a-5p	HITS-CLIP	19536157
MIRT628026	hsa-miR-6769b-5p	HITS-CLIP	19536157
MIRT623327	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT623326	hsa-miR-3663-3p	HITS-CLIP	23824327
MIRT623325	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT628027	hsa-miR-6769a-5p	HITS-CLIP	23824327
MIRT628026	hsa-miR-6769b-5p	HITS-CLIP	23824327
MIRT623324	hsa-miR-8055	HITS-CLIP	23824327
MIRT628025	hsa-miR-6885-3p	HITS-CLIP	23824327
MIRT623323	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT623327	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT623326	hsa-miR-3663-3p	HITS-CLIP	23824327
MIRT623325	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT628027	hsa-miR-6769a-5p	HITS-CLIP	23824327
MIRT628026	hsa-miR-6769b-5p	HITS-CLIP	23824327
MIRT623324	hsa-miR-8055	HITS-CLIP	23824327
MIRT628025	hsa-miR-6885-3p	HITS-CLIP	23824327
MIRT623327	hsa-miR-552-3p	HITS-CLIP	23824327
MIRT623326	hsa-miR-3663-3p	HITS-CLIP	23824327
MIRT623325	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT623324	hsa-miR-8055	HITS-CLIP	23824327
MIRT623323	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT2036049	hsa-miR-4420	CLIP-seq
MIRT2036050	hsa-miR-554	CLIP-seq
MIRT2036051	hsa-miR-570	CLIP-seq
MIRT2390489	hsa-miR-1915	CLIP-seq
MIRT2390490	hsa-miR-3141	CLIP-seq
MIRT2390491	hsa-miR-4685-5p	CLIP-seq
MIRT2565551	hsa-miR-1	CLIP-seq
MIRT2565552	hsa-miR-106a	CLIP-seq
MIRT2565553	hsa-miR-106b	CLIP-seq
MIRT2565554	hsa-miR-1182	CLIP-seq
MIRT2565555	hsa-miR-1183	CLIP-seq
MIRT2565556	hsa-miR-1207-5p	CLIP-seq
MIRT2565557	hsa-miR-1264	CLIP-seq
MIRT2565558	hsa-miR-1273f	CLIP-seq
MIRT2565559	hsa-miR-1291	CLIP-seq
MIRT2565560	hsa-miR-132	CLIP-seq
MIRT2565561	hsa-miR-1323	CLIP-seq
MIRT2565562	hsa-miR-141	CLIP-seq
MIRT2565563	hsa-miR-146a	CLIP-seq
MIRT2565564	hsa-miR-147	CLIP-seq
MIRT2565565	hsa-miR-1587	CLIP-seq
MIRT2565566	hsa-miR-17	CLIP-seq
MIRT2565567	hsa-miR-188-5p	CLIP-seq
MIRT2565568	hsa-miR-1909	CLIP-seq
MIRT2565569	hsa-miR-1913	CLIP-seq
MIRT2390489	hsa-miR-1915	CLIP-seq
MIRT2565570	hsa-miR-19a	CLIP-seq
MIRT2565571	hsa-miR-19b	CLIP-seq
MIRT2565572	hsa-miR-200a	CLIP-seq
MIRT2565573	hsa-miR-204	CLIP-seq
MIRT2565574	hsa-miR-206	CLIP-seq
MIRT2565575	hsa-miR-20a	CLIP-seq
MIRT2565576	hsa-miR-20b	CLIP-seq
MIRT2565577	hsa-miR-211	CLIP-seq
MIRT2565578	hsa-miR-2113	CLIP-seq
MIRT2565579	hsa-miR-212	CLIP-seq
MIRT2565580	hsa-miR-300	CLIP-seq
MIRT2565581	hsa-miR-31	CLIP-seq
MIRT2565582	hsa-miR-3121-5p	CLIP-seq
MIRT2565583	hsa-miR-3123	CLIP-seq
MIRT2565584	hsa-miR-3125	CLIP-seq
MIRT2565585	hsa-miR-3140-5p	CLIP-seq
MIRT2390490	hsa-miR-3141	CLIP-seq
MIRT2565586	hsa-miR-3147	CLIP-seq
MIRT2565587	hsa-miR-3152-5p	CLIP-seq
MIRT2565588	hsa-miR-3174	CLIP-seq
MIRT2565589	hsa-miR-3180	CLIP-seq
MIRT2565590	hsa-miR-3180-3p	CLIP-seq
MIRT2565591	hsa-miR-3196	CLIP-seq
MIRT2565592	hsa-miR-3201	CLIP-seq
MIRT2565593	hsa-miR-324-3p	CLIP-seq
MIRT2565594	hsa-miR-324-5p	CLIP-seq
MIRT2565595	hsa-miR-328	CLIP-seq
MIRT2565596	hsa-miR-342-5p	CLIP-seq
MIRT2565597	hsa-miR-346	CLIP-seq
MIRT2565598	hsa-miR-3655	CLIP-seq
MIRT2565599	hsa-miR-3671	CLIP-seq
MIRT2565600	hsa-miR-3673	CLIP-seq
MIRT2565601	hsa-miR-3675-5p	CLIP-seq
MIRT2565602	hsa-miR-3691-3p	CLIP-seq
MIRT2565603	hsa-miR-371-5p	CLIP-seq
MIRT2565604	hsa-miR-371b-5p	CLIP-seq
MIRT2565605	hsa-miR-381	CLIP-seq
MIRT2565606	hsa-miR-3910	CLIP-seq
MIRT2565607	hsa-miR-3913-3p	CLIP-seq
MIRT2565608	hsa-miR-3916	CLIP-seq
MIRT2565609	hsa-miR-3925-5p	CLIP-seq
MIRT2565610	hsa-miR-3960	CLIP-seq
MIRT2565611	hsa-miR-425	CLIP-seq
MIRT2565612	hsa-miR-4268	CLIP-seq
MIRT2565613	hsa-miR-4269	CLIP-seq
MIRT2565614	hsa-miR-4279	CLIP-seq
MIRT2565615	hsa-miR-4302	CLIP-seq
MIRT2565616	hsa-miR-4308	CLIP-seq
MIRT2565617	hsa-miR-4422	CLIP-seq
MIRT2565618	hsa-miR-4425	CLIP-seq
MIRT2565619	hsa-miR-4435	CLIP-seq
MIRT2565620	hsa-miR-4448	CLIP-seq
MIRT2565621	hsa-miR-4467	CLIP-seq
MIRT2565622	hsa-miR-4481	CLIP-seq
MIRT2565623	hsa-miR-4492	CLIP-seq
MIRT2565624	hsa-miR-4498	CLIP-seq
MIRT2565625	hsa-miR-4504	CLIP-seq
MIRT2565626	hsa-miR-4514	CLIP-seq
MIRT2565627	hsa-miR-4527	CLIP-seq
MIRT2565628	hsa-miR-4649-5p	CLIP-seq
MIRT2565629	hsa-miR-4651	CLIP-seq
MIRT2565630	hsa-miR-4656	CLIP-seq
MIRT2565631	hsa-miR-4664-5p	CLIP-seq
MIRT2565632	hsa-miR-4674	CLIP-seq
MIRT2565633	hsa-miR-4675	CLIP-seq
MIRT2390491	hsa-miR-4685-5p	CLIP-seq
MIRT2565634	hsa-miR-4686	CLIP-seq
MIRT2565635	hsa-miR-4692	CLIP-seq
MIRT2565636	hsa-miR-4697-3p	CLIP-seq
MIRT2565637	hsa-miR-4708-3p	CLIP-seq
MIRT2565638	hsa-miR-4731-5p	CLIP-seq
MIRT2565639	hsa-miR-4732-5p	CLIP-seq
MIRT2565640	hsa-miR-4740-3p	CLIP-seq
MIRT2565641	hsa-miR-4741	CLIP-seq
MIRT2565642	hsa-miR-4742-5p	CLIP-seq
MIRT2565643	hsa-miR-4745-5p	CLIP-seq
MIRT2565644	hsa-miR-4758-5p	CLIP-seq
MIRT2565645	hsa-miR-4762-5p	CLIP-seq
MIRT2565646	hsa-miR-4763-3p	CLIP-seq
MIRT2565647	hsa-miR-4768-3p	CLIP-seq
MIRT2565648	hsa-miR-4773	CLIP-seq
MIRT2565649	hsa-miR-4774-3p	CLIP-seq
MIRT2565650	hsa-miR-4791	CLIP-seq
MIRT2565651	hsa-miR-489	CLIP-seq
MIRT2565652	hsa-miR-515-5p	CLIP-seq
MIRT2565653	hsa-miR-519a	CLIP-seq
MIRT2565654	hsa-miR-519b-3p	CLIP-seq
MIRT2565655	hsa-miR-519c-3p	CLIP-seq
MIRT2565656	hsa-miR-519d	CLIP-seq
MIRT2565657	hsa-miR-542-3p	CLIP-seq
MIRT2565658	hsa-miR-548aa	CLIP-seq
MIRT2565659	hsa-miR-548ac	CLIP-seq
MIRT2565660	hsa-miR-548an	CLIP-seq
MIRT2565661	hsa-miR-548d-3p	CLIP-seq
MIRT2565662	hsa-miR-548g	CLIP-seq
MIRT2565663	hsa-miR-548o	CLIP-seq
MIRT2565664	hsa-miR-548p	CLIP-seq
MIRT2565665	hsa-miR-548z	CLIP-seq
MIRT2036051	hsa-miR-570	CLIP-seq
MIRT2565666	hsa-miR-577	CLIP-seq
MIRT2565667	hsa-miR-580	CLIP-seq
MIRT2565668	hsa-miR-589	CLIP-seq
MIRT2565669	hsa-miR-599	CLIP-seq
MIRT2565670	hsa-miR-608	CLIP-seq
MIRT2565671	hsa-miR-613	CLIP-seq
MIRT2565672	hsa-miR-624	CLIP-seq
MIRT2565673	hsa-miR-627	CLIP-seq
MIRT2565674	hsa-miR-629	CLIP-seq
MIRT2565675	hsa-miR-637	CLIP-seq
MIRT2565676	hsa-miR-642b	CLIP-seq
MIRT2565677	hsa-miR-758	CLIP-seq
MIRT2565678	hsa-miR-762	CLIP-seq
MIRT2565679	hsa-miR-924	CLIP-seq
MIRT2565680	hsa-miR-93	CLIP-seq
MIRT2565552	hsa-miR-106a	CLIP-seq
MIRT2565553	hsa-miR-106b	CLIP-seq
MIRT2565554	hsa-miR-1182	CLIP-seq
MIRT2565555	hsa-miR-1183	CLIP-seq
MIRT2565556	hsa-miR-1207-5p	CLIP-seq
MIRT2565557	hsa-miR-1264	CLIP-seq
MIRT2565558	hsa-miR-1273f	CLIP-seq
MIRT2565560	hsa-miR-132	CLIP-seq
MIRT2565561	hsa-miR-1323	CLIP-seq
MIRT2565562	hsa-miR-141	CLIP-seq
MIRT2565563	hsa-miR-146a	CLIP-seq
MIRT2565564	hsa-miR-147	CLIP-seq
MIRT2565565	hsa-miR-1587	CLIP-seq
MIRT2565566	hsa-miR-17	CLIP-seq
MIRT2565567	hsa-miR-188-5p	CLIP-seq
MIRT2565568	hsa-miR-1909	CLIP-seq
MIRT2565569	hsa-miR-1913	CLIP-seq
MIRT2390489	hsa-miR-1915	CLIP-seq
MIRT2565570	hsa-miR-19a	CLIP-seq
MIRT2565571	hsa-miR-19b	CLIP-seq
MIRT2565572	hsa-miR-200a	CLIP-seq
MIRT2565573	hsa-miR-204	CLIP-seq
MIRT2565575	hsa-miR-20a	CLIP-seq
MIRT2565576	hsa-miR-20b	CLIP-seq
MIRT2565577	hsa-miR-211	CLIP-seq
MIRT2565578	hsa-miR-2113	CLIP-seq
MIRT2565579	hsa-miR-212	CLIP-seq
MIRT2565580	hsa-miR-300	CLIP-seq
MIRT2565582	hsa-miR-3121-5p	CLIP-seq
MIRT2565583	hsa-miR-3123	CLIP-seq
MIRT2565584	hsa-miR-3125	CLIP-seq
MIRT2565585	hsa-miR-3140-5p	CLIP-seq
MIRT2390490	hsa-miR-3141	CLIP-seq
MIRT2565586	hsa-miR-3147	CLIP-seq
MIRT2565587	hsa-miR-3152-5p	CLIP-seq
MIRT2565589	hsa-miR-3180	CLIP-seq
MIRT2565590	hsa-miR-3180-3p	CLIP-seq
MIRT2565591	hsa-miR-3196	CLIP-seq
MIRT2565592	hsa-miR-3201	CLIP-seq
MIRT2565593	hsa-miR-324-3p	CLIP-seq
MIRT2565594	hsa-miR-324-5p	CLIP-seq
MIRT2565596	hsa-miR-342-5p	CLIP-seq
MIRT2565597	hsa-miR-346	CLIP-seq
MIRT2565598	hsa-miR-3655	CLIP-seq
MIRT2565599	hsa-miR-3671	CLIP-seq
MIRT2565601	hsa-miR-3675-5p	CLIP-seq
MIRT2565602	hsa-miR-3691-3p	CLIP-seq
MIRT2565603	hsa-miR-371-5p	CLIP-seq
MIRT2565604	hsa-miR-371b-5p	CLIP-seq
MIRT2565605	hsa-miR-381	CLIP-seq
MIRT2565606	hsa-miR-3910	CLIP-seq
MIRT2565607	hsa-miR-3913-3p	CLIP-seq
MIRT2565608	hsa-miR-3916	CLIP-seq
MIRT2565609	hsa-miR-3925-5p	CLIP-seq
MIRT2565610	hsa-miR-3960	CLIP-seq
MIRT2565611	hsa-miR-425	CLIP-seq
MIRT2565613	hsa-miR-4269	CLIP-seq
MIRT2565614	hsa-miR-4279	CLIP-seq
MIRT2565615	hsa-miR-4302	CLIP-seq
MIRT2565617	hsa-miR-4422	CLIP-seq
MIRT2565618	hsa-miR-4425	CLIP-seq
MIRT2565619	hsa-miR-4435	CLIP-seq
MIRT2565621	hsa-miR-4467	CLIP-seq
MIRT2565623	hsa-miR-4492	CLIP-seq
MIRT2565624	hsa-miR-4498	CLIP-seq
MIRT2565625	hsa-miR-4504	CLIP-seq
MIRT2565626	hsa-miR-4514	CLIP-seq
MIRT2565627	hsa-miR-4527	CLIP-seq
MIRT2565628	hsa-miR-4649-5p	CLIP-seq
MIRT2565629	hsa-miR-4651	CLIP-seq
MIRT2565630	hsa-miR-4656	CLIP-seq
MIRT2565631	hsa-miR-4664-5p	CLIP-seq
MIRT2565632	hsa-miR-4674	CLIP-seq
MIRT2565633	hsa-miR-4675	CLIP-seq
MIRT2390491	hsa-miR-4685-5p	CLIP-seq
MIRT2565634	hsa-miR-4686	CLIP-seq
MIRT2565635	hsa-miR-4692	CLIP-seq
MIRT2565636	hsa-miR-4697-3p	CLIP-seq
MIRT2565637	hsa-miR-4708-3p	CLIP-seq
MIRT2565638	hsa-miR-4731-5p	CLIP-seq
MIRT2565639	hsa-miR-4732-5p	CLIP-seq
MIRT2565640	hsa-miR-4740-3p	CLIP-seq
MIRT2565641	hsa-miR-4741	CLIP-seq
MIRT2565642	hsa-miR-4742-5p	CLIP-seq
MIRT2565645	hsa-miR-4762-5p	CLIP-seq
MIRT2565646	hsa-miR-4763-3p	CLIP-seq
MIRT2565647	hsa-miR-4768-3p	CLIP-seq
MIRT2565648	hsa-miR-4773	CLIP-seq
MIRT2565649	hsa-miR-4774-3p	CLIP-seq
MIRT2565650	hsa-miR-4791	CLIP-seq
MIRT2565651	hsa-miR-489	CLIP-seq
MIRT2565652	hsa-miR-515-5p	CLIP-seq
MIRT2565653	hsa-miR-519a	CLIP-seq
MIRT2565654	hsa-miR-519b-3p	CLIP-seq
MIRT2565655	hsa-miR-519c-3p	CLIP-seq
MIRT2565656	hsa-miR-519d	CLIP-seq
MIRT2565657	hsa-miR-542-3p	CLIP-seq
MIRT2565658	hsa-miR-548aa	CLIP-seq
MIRT2565659	hsa-miR-548ac	CLIP-seq
MIRT2565660	hsa-miR-548an	CLIP-seq
MIRT2565661	hsa-miR-548d-3p	CLIP-seq
MIRT2565662	hsa-miR-548g	CLIP-seq
MIRT2565663	hsa-miR-548o	CLIP-seq
MIRT2565664	hsa-miR-548p	CLIP-seq
MIRT2565665	hsa-miR-548z	CLIP-seq
MIRT2036051	hsa-miR-570	CLIP-seq
MIRT2565666	hsa-miR-577	CLIP-seq
MIRT2565667	hsa-miR-580	CLIP-seq
MIRT2565668	hsa-miR-589	CLIP-seq
MIRT2565669	hsa-miR-599	CLIP-seq
MIRT2565670	hsa-miR-608	CLIP-seq
MIRT2565672	hsa-miR-624	CLIP-seq
MIRT2565673	hsa-miR-627	CLIP-seq
MIRT2565674	hsa-miR-629	CLIP-seq
MIRT2565675	hsa-miR-637	CLIP-seq
MIRT2565676	hsa-miR-642b	CLIP-seq
MIRT2565677	hsa-miR-758	CLIP-seq
MIRT2565678	hsa-miR-762	CLIP-seq
MIRT2565679	hsa-miR-924	CLIP-seq
MIRT2565680	hsa-miR-93	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IBA
GO:0000139	Component	Golgi membrane	IEA
GO:0000139	Component	Golgi membrane	TAS	10915796
GO:0004571	Function	Mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	IBA
GO:0004571	Function	Mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	IEA
GO:0004571	Function	Mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	TAS	10915796
GO:0005509	Function	Calcium ion binding	IEA
GO:0005509	Function	Calcium ion binding	TAS	10915796
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005783	Component	Endoplasmic reticulum	IBA
GO:0005794	Component	Golgi apparatus	IEA
GO:0005975	Process	Carbohydrate metabolic process	IEA
GO:0006486	Process	Protein glycosylation	IEA
GO:0006487	Process	Protein N-linked glycosylation	TAS	10915796
GO:0006491	Process	N-glycan processing	IEA
GO:0016020	Component	Membrane	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0016798	Function	Hydrolase activity, acting on glycosyl bonds	IEA
GO:0036503	Process	ERAD pathway	IBA
GO:0046872	Function	Metal ion binding	IEA
GO:0070062	Component	Extracellular exosome	HDA	23533145
GO:1904381	Process	Golgi apparatus mannose trimming	TAS

Other IDs

• MIM: 616772
• HGNC: 19080
• e!Ensembl: ENSG00000117643

Protein

• UniProt ID: Q9NR34
• Protein name: Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC (EC 3.2.1.113) (HMIC) (Mannosidase alpha class 1C member 1) (Processing alpha-1,2-mannosidase IC) (Alpha-1,2-mannosidase IC)
• Protein function: Involved in the maturation of Asn-linked oligosaccharides. Trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce first Man(8)GlcNAc(2) then Man(6)GlcNAc and a small amount of Man(5)GlcNAc.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01532	Glyco_hydro_47	181 → 617	Glycosyl hydrolase family 47	Domain

• Tissue specificity: TISSUE SPECIFICITY: Expressed in most tissues with the exception of lung, muscle and pancreas. Highly expressed in placenta.
• Sequence:

  MLMRKVPGFVPASPWGLRLPQKFLFLLFLSGLVTLCFGALFLLPHSSRLKRLFLAPRTQQ
  PGLEVVAEIAGHAPAREQEPPPNPAPAAPAPGEDDPSSWASPRRRKGGLRRTRPTGPREE
  ATAARGNSIPASRPGDEGVPFRFDFNAFRSRLRHPVLGTRADESQEPQSQVRAQREKIKE
  MMQFAWQSYKRYAMGKNELRPLTKDGYEGNMFGGLSGATVIDSLDTLYLMELKEEFQEAK
  AWVGESFHLNVSGEASLFEVNIRYIGGLLSAFYLTGEEVFRIKAIRLGEKLLPAFNTPTG
  IPKGVVSFKSGNWGWATAGSSSILAEFGSLHLEFLHLTELSGNQVFAEKVRNIRKVLRKI
  EKPFGLYPNFLSPVSGNWVQHHVSVGGLGDSFYEYLIKSWLMSGKTDMEAKNMYYEALEA
  IETYLLNVSPGGLTYIAEWRGGILDHKMGHLACFSGGMIALGAEDAKEEKRAHYRELAAQ
  ITKTCHESYARSDTKLGPEAFWFNSGREAVATQLSESYYILRPEVVESYMYLWRQTHNPI
  YREWGWEVVLALEKYCRTEAGFSGIQDVYSSTPNHDNKQQSFFLAETLKYLYLLFSEDDL
  LSLEDWVFNTEAHPLPVNHSDSSGRAWGRH

• Sequence length: 630

Pathways

KEGG:

N-Glycan biosynthesis
Various types of N-glycan biosynthesis
Metabolic pathways
Protein processing in endoplasmic reticulum

Reactome:

Intra-Golgi traffic
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2

Associated diseases

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
MAN1C1-related disorder	Likely benign; Benign; Uncertain significance	rs371173401, rs1228948770, rs187331964, rs150201998, rs79893268, rs139260749, rs573023765, rs377564466, rs116009723	RCV003912292 RCV003911474 RCV003909591 RCV003914447 RCV003922152 RCV003946936 RCV003957219 RCV004758297 RCV003916163

Associations from Text Mining
Disease Name	Relationship Type	References
Aging Premature	Associate	21966431
Carcinogenesis	Associate	38117655
Cholangiocarcinoma	Associate	38117655
Emphysema	Associate	24383474
Glioblastoma	Associate	39333557
Glioma	Associate	39333557
Inflammation	Stimulate	39333557
Neoplasms	Associate	35065254
Ovarian Neoplasms	Associate	39972314
Parkinson Disease	Associate	26510930
Stomach Neoplasms	Associate	35065254