Gene Gene information from NCBI Gene database.
Entrez ID 57132
Gene name Charged multivesicular body protein 1B
Gene symbol CHMP1B
Synonyms (NCBI Gene)
C10orf2C18-ORF2C18orf2CHMP1.5Vps46-2Vps46BhVps46-2
Chromosome 18
Chromosome location 18p11.21
Summary CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor p
miRNA miRNA information provided by mirtarbase database.
658
miRTarBase ID miRNA Experiments Reference
MIRT661499 hsa-miR-3929 HITS-CLIP 23824327
MIRT661498 hsa-miR-4419b HITS-CLIP 23824327
MIRT661497 hsa-miR-4478 HITS-CLIP 23824327
MIRT661496 hsa-miR-3622a-3p HITS-CLIP 23824327
MIRT661495 hsa-miR-3622b-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
72
GO ID Ontology Definition Evidence Reference
GO:0000421 Component Autophagosome membrane IDA 17984323
GO:0000776 Component Kinetochore IDA 26040712
GO:0000776 Component Kinetochore IEA
GO:0000815 Component ESCRT III complex IBA
GO:0000815 Component ESCRT III complex IDA 24878737
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
606486 24287 ENSG00000255112
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q7LBR1
Protein name Charged multivesicular body protein 1b (CHMP1.5) (Chromatin-modifying protein 1b) (CHMP1b) (Vacuolar protein sorting-associated protein 46-2) (Vps46-2) (hVps46-2)
Protein function Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intral
PDB 3EAB , 3JC1 , 4TXQ , 4TXR , 6E8G , 6TZ4 , 6TZ5 , 6TZ9 , 8V2Q , 8V2R , 8V2S
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03357 Snf7 7 176 Snf7 Family
Tissue specificity TISSUE SPECIFICITY: Widely expressed. Expressed in pancreas, kidney, skeletal muscle, liver, lung, placenta and brain. {ECO:0000269|PubMed:11474171}.
Sequence
Sequence length 199
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG 
  Virion - Hepatitis viruses
Endocytosis
Necroptosis