CHMP1B (charged multivesicular body protein 1B)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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57132 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Charged multivesicular body protein 1B |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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CHMP1B |
Synonyms (NCBI Gene)
Gene synonyms aliases
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C10orf2, C18-ORF2, C18orf2, CHMP1.5, Vps46-2, Vps46B, hVps46-2 |
Chromosome
Chromosome number
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18 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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18p11.21 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor p |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q7LBR1 | ||||||||||
Protein name | Charged multivesicular body protein 1b (CHMP1.5) (Chromatin-modifying protein 1b) (CHMP1b) (Vacuolar protein sorting-associated protein 46-2) (Vps46-2) (hVps46-2) | ||||||||||
Protein function | Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intral | ||||||||||
PDB | 3EAB , 3JC1 , 4TXQ , 4TXR , 6E8G , 6TZ4 , 6TZ5 , 6TZ9 , 8V2Q , 8V2R , 8V2S | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Widely expressed. Expressed in pancreas, kidney, skeletal muscle, liver, lung, placenta and brain. {ECO:0000269|PubMed:11474171}. | ||||||||||
Sequence |
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Sequence length | 199 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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