Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
57132
Gene name Gene Name - the full gene name approved by the HGNC.
Charged multivesicular body protein 1B
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
CHMP1B
Synonyms (NCBI Gene) Gene synonyms aliases
C10orf2, C18-ORF2, C18orf2, CHMP1.5, Vps46-2, Vps46B, hVps46-2
Chromosome Chromosome number
18
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
18p11.21
Summary Summary of gene provided in NCBI Entrez Gene.
CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor p
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT661499 hsa-miR-3929 HITS-CLIP 23824327
MIRT661498 hsa-miR-4419b HITS-CLIP 23824327
MIRT661497 hsa-miR-4478 HITS-CLIP 23824327
MIRT661496 hsa-miR-3622a-3p HITS-CLIP 23824327
MIRT661495 hsa-miR-3622b-3p HITS-CLIP 23824327
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000815 Component ESCRT III complex IBA 21873635
GO:0000815 Component ESCRT III complex IDA 24878737
GO:0005515 Function Protein binding IPI 14505570, 14519844, 16730941, 17711858, 17928862, 18385515, 18997780, 19129479, 19129480, 19302785, 19525971, 21543490, 21827950, 21988832, 23045692, 23105106, 25416956, 26634441, 31515488, 32296183
GO:0005654 Component Nucleoplasm IDA
GO:0005771 Component Multivesicular body IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
606486 24287 ENSG00000255112
Protein
UniProt ID Q7LBR1
Protein name Charged multivesicular body protein 1b (CHMP1.5) (Chromatin-modifying protein 1b) (CHMP1b) (Vacuolar protein sorting-associated protein 46-2) (Vps46-2) (hVps46-2)
Protein function Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intral
PDB 3EAB , 3JC1 , 4TXQ , 4TXR , 6E8G , 6TZ4 , 6TZ5 , 6TZ9 , 8V2Q , 8V2R , 8V2S
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03357 Snf7 7 176 Snf7 Family
Tissue specificity TISSUE SPECIFICITY: Widely expressed. Expressed in pancreas, kidney, skeletal muscle, liver, lung, placenta and brain. {ECO:0000269|PubMed:11474171}.
Sequence
Sequence length 199
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  Virion - Hepatitis viruses
Endocytosis
Necroptosis