Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	57128
Gene name Gene Name - the full gene name approved by the HGNC.	LYR motif containing 4
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	LYRM4
Synonyms (NCBI Gene) Gene synonyms aliases	C6orf149, CGI-203, COXPD19, ISD11
Chromosome Chromosome number	6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	6p25.1
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is found in both mitochondria and the nucleus, where it binds cysteine desulfurase and helps free inorganic sulfur for Fe/S clusters. Disruption of this gene negatively impacts mitochondrial and cytosolic iron homeostasis.

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miRTarBase ID	miRNA	Experiments	Reference
MIRT710697	hsa-miR-4459	HITS-CLIP	19536157
MIRT710696	hsa-miR-665	HITS-CLIP	19536157
MIRT710695	hsa-miR-6840-3p	HITS-CLIP	19536157
MIRT710694	hsa-miR-6134	HITS-CLIP	19536157
MIRT458154	hsa-miR-377-5p	HITS-CLIP	19536157
MIRT458153	hsa-miR-6086	HITS-CLIP	19536157
MIRT458172	hsa-miR-6499-3p	HITS-CLIP	19536157
MIRT710693	hsa-miR-3689d	HITS-CLIP	19536157
MIRT710692	hsa-miR-6851-5p	HITS-CLIP	19536157
MIRT710691	hsa-miR-6880-5p	HITS-CLIP	19536157
MIRT710690	hsa-miR-7847-3p	HITS-CLIP	19536157
MIRT458168	hsa-miR-6807-5p	HITS-CLIP	19536157
MIRT458167	hsa-miR-455-3p	HITS-CLIP	19536157
MIRT458165	hsa-miR-6516-5p	HITS-CLIP	19536157
MIRT702181	hsa-miR-1273e	HITS-CLIP	19536157
MIRT458164	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT458168	hsa-miR-6807-5p	HITS-CLIP	23313552
MIRT458167	hsa-miR-455-3p	HITS-CLIP	23313552
MIRT458165	hsa-miR-6516-5p	HITS-CLIP	23313552
MIRT458163	hsa-miR-1910-3p	HITS-CLIP	23313552
MIRT458162	hsa-miR-6511a-5p	HITS-CLIP	23313552
MIRT458161	hsa-miR-3174	HITS-CLIP	23313552
MIRT458159	hsa-miR-4257	HITS-CLIP	23313552
MIRT458160	hsa-miR-1247-3p	HITS-CLIP	23313552
MIRT458158	hsa-miR-3160-3p	HITS-CLIP	23313552
MIRT458157	hsa-miR-558	HITS-CLIP	23313552
MIRT458155	hsa-miR-4487	HITS-CLIP	23313552
MIRT458156	hsa-miR-1827	HITS-CLIP	23313552
MIRT458154	hsa-miR-377-5p	HITS-CLIP	23313552
MIRT458153	hsa-miR-6086	HITS-CLIP	23313552
MIRT458152	hsa-miR-2467-3p	HITS-CLIP	23313552
MIRT458151	hsa-miR-3612	HITS-CLIP	23313552
MIRT458150	hsa-miR-650	HITS-CLIP	23313552
MIRT458149	hsa-miR-6073	HITS-CLIP	23313552
MIRT458148	hsa-miR-142-3p	HITS-CLIP	23313552
MIRT458147	hsa-miR-921	HITS-CLIP	23313552
MIRT702181	hsa-miR-1273e	HITS-CLIP	23313552
MIRT702180	hsa-miR-2681-3p	HITS-CLIP	23313552
MIRT702179	hsa-miR-4645-5p	HITS-CLIP	23313552
MIRT702178	hsa-miR-4673	HITS-CLIP	23313552
MIRT702177	hsa-miR-215-3p	HITS-CLIP	23313552
MIRT458172	hsa-miR-6499-3p	HITS-CLIP	23313552
MIRT702176	hsa-miR-3135b	HITS-CLIP	23313552
MIRT702175	hsa-miR-504-3p	HITS-CLIP	23313552
MIRT702174	hsa-miR-122-5p	HITS-CLIP	23313552
MIRT702173	hsa-miR-3652	HITS-CLIP	23313552
MIRT702172	hsa-miR-4430	HITS-CLIP	23313552
MIRT702171	hsa-miR-4466	HITS-CLIP	23313552
MIRT702170	hsa-miR-675-5p	HITS-CLIP	23313552
MIRT702169	hsa-miR-143-5p	HITS-CLIP	23313552
MIRT702168	hsa-miR-5698	HITS-CLIP	23313552
MIRT687620	hsa-miR-6771-3p	HITS-CLIP	23313552
MIRT458176	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT687619	hsa-miR-151a-5p	HITS-CLIP	23313552
MIRT687618	hsa-miR-151b	HITS-CLIP	23313552
MIRT687617	hsa-miR-3190-5p	HITS-CLIP	23313552
MIRT687616	hsa-miR-3926	HITS-CLIP	23313552
MIRT687615	hsa-miR-3606-5p	HITS-CLIP	23313552
MIRT219209	hsa-miR-548s	HITS-CLIP	23313552
MIRT458163	hsa-miR-1910-3p	HITS-CLIP	23706177
MIRT458162	hsa-miR-6511a-5p	HITS-CLIP	23706177
MIRT458161	hsa-miR-3174	HITS-CLIP	23706177
MIRT458159	hsa-miR-4257	HITS-CLIP	23706177
MIRT458160	hsa-miR-1247-3p	HITS-CLIP	23706177
MIRT681419	hsa-miR-5186	HITS-CLIP	23706177
MIRT458158	hsa-miR-3160-3p	HITS-CLIP	23706177
MIRT458157	hsa-miR-558	HITS-CLIP	23706177
MIRT458155	hsa-miR-4487	HITS-CLIP	23706177
MIRT458156	hsa-miR-1827	HITS-CLIP	23706177
MIRT458154	hsa-miR-377-5p	HITS-CLIP	23706177
MIRT458153	hsa-miR-6086	HITS-CLIP	23706177
MIRT458152	hsa-miR-2467-3p	HITS-CLIP	23706177
MIRT458151	hsa-miR-3612	HITS-CLIP	23706177
MIRT458150	hsa-miR-650	HITS-CLIP	23706177
MIRT458149	hsa-miR-6073	HITS-CLIP	23706177
MIRT458148	hsa-miR-142-3p	HITS-CLIP	23706177
MIRT458147	hsa-miR-921	HITS-CLIP	23706177
MIRT670506	hsa-miR-4787-5p	HITS-CLIP	23824327
MIRT670505	hsa-miR-4284	HITS-CLIP	23824327
MIRT670504	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT670503	hsa-miR-3180	HITS-CLIP	23824327
MIRT670502	hsa-miR-3180-3p	HITS-CLIP	23824327
MIRT670501	hsa-miR-3196	HITS-CLIP	23824327
MIRT670500	hsa-miR-6816-5p	HITS-CLIP	23824327
MIRT670499	hsa-miR-1237-5p	HITS-CLIP	23824327
MIRT670498	hsa-miR-4488	HITS-CLIP	23824327
MIRT670497	hsa-miR-4697-5p	HITS-CLIP	23824327
MIRT670496	hsa-miR-7977	HITS-CLIP	23824327
MIRT458177	hsa-miR-508-5p	PAR-CLIP	21572407
MIRT458176	hsa-miR-6849-3p	PAR-CLIP	21572407
MIRT458175	hsa-miR-6742-3p	PAR-CLIP	21572407
MIRT458174	hsa-miR-766-3p	PAR-CLIP	21572407
MIRT458173	hsa-miR-4793-3p	PAR-CLIP	21572407
MIRT542118	hsa-miR-6776-5p	PAR-CLIP	21572407
MIRT458171	hsa-miR-661	PAR-CLIP	21572407
MIRT542117	hsa-miR-542-3p	PAR-CLIP	21572407
MIRT458170	hsa-miR-6512-3p	PAR-CLIP	21572407
MIRT458169	hsa-miR-6720-5p	PAR-CLIP	21572407
MIRT458166	hsa-miR-7703	PAR-CLIP	21572407
MIRT542116	hsa-miR-1262	PAR-CLIP	21572407
MIRT542115	hsa-miR-4701-3p	PAR-CLIP	21572407
MIRT542114	hsa-miR-6736-5p	PAR-CLIP	21572407
MIRT458164	hsa-miR-1273g-3p	PAR-CLIP	21572407
MIRT495154	hsa-miR-1224-3p	PAR-CLIP	23708386
MIRT495153	hsa-miR-4286	PAR-CLIP	23708386
MIRT495152	hsa-miR-377-3p	PAR-CLIP	23708386
MIRT458177	hsa-miR-508-5p	PAR-CLIP	23592263
MIRT458176	hsa-miR-6849-3p	PAR-CLIP	23592263
MIRT458175	hsa-miR-6742-3p	PAR-CLIP	23592263
MIRT458174	hsa-miR-766-3p	PAR-CLIP	23592263
MIRT458173	hsa-miR-4793-3p	PAR-CLIP	23592263
MIRT458172	hsa-miR-6499-3p	PAR-CLIP	23592263
MIRT458171	hsa-miR-661	PAR-CLIP	23592263
MIRT458170	hsa-miR-6512-3p	PAR-CLIP	23592263
MIRT458169	hsa-miR-6720-5p	PAR-CLIP	23592263
MIRT458168	hsa-miR-6807-5p	PAR-CLIP	23592263
MIRT458166	hsa-miR-7703	PAR-CLIP	23592263
MIRT458167	hsa-miR-455-3p	PAR-CLIP	23592263
MIRT458165	hsa-miR-6516-5p	PAR-CLIP	23592263
MIRT458164	hsa-miR-1273g-3p	PAR-CLIP	23592263
MIRT458163	hsa-miR-1910-3p	PAR-CLIP	23592263
MIRT458162	hsa-miR-6511a-5p	PAR-CLIP	23592263
MIRT458161	hsa-miR-3174	PAR-CLIP	23592263
MIRT458159	hsa-miR-4257	PAR-CLIP	23592263
MIRT458160	hsa-miR-1247-3p	PAR-CLIP	23592263
MIRT458158	hsa-miR-3160-3p	PAR-CLIP	23592263
MIRT458157	hsa-miR-558	PAR-CLIP	23592263
MIRT458155	hsa-miR-4487	PAR-CLIP	23592263
MIRT458156	hsa-miR-1827	PAR-CLIP	23592263
MIRT458154	hsa-miR-377-5p	PAR-CLIP	23592263
MIRT458153	hsa-miR-6086	PAR-CLIP	23592263
MIRT458152	hsa-miR-2467-3p	PAR-CLIP	23592263
MIRT458151	hsa-miR-3612	PAR-CLIP	23592263
MIRT458150	hsa-miR-650	PAR-CLIP	23592263
MIRT458149	hsa-miR-6073	PAR-CLIP	23592263
MIRT458148	hsa-miR-142-3p	PAR-CLIP	23592263
MIRT458147	hsa-miR-921	PAR-CLIP	23592263
MIRT458160	hsa-miR-1247-3p	PAR-CLIP	26701625
MIRT458160	hsa-miR-1247-3p	PAR-CLIP	26701625
MIRT458148	hsa-miR-142-3p	PAR-CLIP	26701625
MIRT458148	hsa-miR-142-3p	PAR-CLIP	26701625
MIRT458156	hsa-miR-1827	PAR-CLIP	26701625
MIRT458156	hsa-miR-1827	PAR-CLIP	26701625
MIRT458163	hsa-miR-1910-3p	PAR-CLIP	26701625
MIRT458163	hsa-miR-1910-3p	PAR-CLIP	26701625
MIRT458152	hsa-miR-2467-3p	PAR-CLIP	26701625
MIRT458152	hsa-miR-2467-3p	PAR-CLIP	26701625
MIRT458158	hsa-miR-3160-3p	PAR-CLIP	26701625
MIRT458158	hsa-miR-3160-3p	PAR-CLIP	26701625
MIRT458161	hsa-miR-3174	PAR-CLIP	26701625
MIRT458161	hsa-miR-3174	PAR-CLIP	26701625
MIRT458151	hsa-miR-3612	PAR-CLIP	26701625
MIRT458151	hsa-miR-3612	PAR-CLIP	26701625
MIRT458154	hsa-miR-377-5p	PAR-CLIP	26701625
MIRT458154	hsa-miR-377-5p	PAR-CLIP	26701625
MIRT458159	hsa-miR-4257	PAR-CLIP	26701625
MIRT458159	hsa-miR-4257	PAR-CLIP	26701625
MIRT458155	hsa-miR-4487	PAR-CLIP	26701625
MIRT458155	hsa-miR-4487	PAR-CLIP	26701625
MIRT458157	hsa-miR-558	PAR-CLIP	26701625
MIRT458157	hsa-miR-558	PAR-CLIP	26701625
MIRT458149	hsa-miR-6073	PAR-CLIP	26701625
MIRT458149	hsa-miR-6073	PAR-CLIP	26701625
MIRT458153	hsa-miR-6086	PAR-CLIP	26701625
MIRT458153	hsa-miR-6086	PAR-CLIP	26701625
MIRT458150	hsa-miR-650	PAR-CLIP	26701625
MIRT458150	hsa-miR-650	PAR-CLIP	26701625
MIRT458162	hsa-miR-6511a-5p	PAR-CLIP	26701625
MIRT458162	hsa-miR-6511a-5p	PAR-CLIP	26701625
MIRT458147	hsa-miR-921	PAR-CLIP	26701625
MIRT458147	hsa-miR-921	PAR-CLIP	26701625
MIRT702181	hsa-miR-1273e	PAR-CLIP	27292025
MIRT710693	hsa-miR-3689d	PAR-CLIP	27292025
MIRT458154	hsa-miR-377-5p	PAR-CLIP	27292025
MIRT710697	hsa-miR-4459	PAR-CLIP	27292025
MIRT458167	hsa-miR-455-3p	PAR-CLIP	27292025
MIRT458153	hsa-miR-6086	PAR-CLIP	27292025
MIRT710694	hsa-miR-6134	PAR-CLIP	27292025
MIRT458172	hsa-miR-6499-3p	PAR-CLIP	27292025
MIRT458165	hsa-miR-6516-5p	PAR-CLIP	27292025
MIRT710696	hsa-miR-665	PAR-CLIP	27292025
MIRT458168	hsa-miR-6807-5p	PAR-CLIP	27292025
MIRT710695	hsa-miR-6840-3p	PAR-CLIP	27292025
MIRT710692	hsa-miR-6851-5p	PAR-CLIP	27292025
MIRT710691	hsa-miR-6880-5p	PAR-CLIP	27292025
MIRT710690	hsa-miR-7847-3p	PAR-CLIP	27292025
MIRT710697	hsa-miR-4459	HITS-CLIP	19536157
MIRT710696	hsa-miR-665	HITS-CLIP	19536157
MIRT710695	hsa-miR-6840-3p	HITS-CLIP	19536157
MIRT710694	hsa-miR-6134	HITS-CLIP	19536157
MIRT458154	hsa-miR-377-5p	HITS-CLIP	19536157
MIRT458153	hsa-miR-6086	HITS-CLIP	19536157
MIRT458172	hsa-miR-6499-3p	HITS-CLIP	19536157
MIRT710693	hsa-miR-3689d	HITS-CLIP	19536157
MIRT710692	hsa-miR-6851-5p	HITS-CLIP	19536157
MIRT710691	hsa-miR-6880-5p	HITS-CLIP	19536157
MIRT710690	hsa-miR-7847-3p	HITS-CLIP	19536157
MIRT458168	hsa-miR-6807-5p	HITS-CLIP	19536157
MIRT458167	hsa-miR-455-3p	HITS-CLIP	19536157
MIRT458165	hsa-miR-6516-5p	HITS-CLIP	19536157
MIRT702181	hsa-miR-1273e	HITS-CLIP	19536157
MIRT458164	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT458168	hsa-miR-6807-5p	HITS-CLIP	23313552
MIRT458167	hsa-miR-455-3p	HITS-CLIP	23313552
MIRT458165	hsa-miR-6516-5p	HITS-CLIP	23313552
MIRT458163	hsa-miR-1910-3p	HITS-CLIP	23313552
MIRT458162	hsa-miR-6511a-5p	HITS-CLIP	23313552
MIRT458161	hsa-miR-3174	HITS-CLIP	23313552
MIRT458159	hsa-miR-4257	HITS-CLIP	23313552
MIRT458160	hsa-miR-1247-3p	HITS-CLIP	23313552
MIRT458158	hsa-miR-3160-3p	HITS-CLIP	23313552
MIRT458157	hsa-miR-558	HITS-CLIP	23313552
MIRT458155	hsa-miR-4487	HITS-CLIP	23313552
MIRT458156	hsa-miR-1827	HITS-CLIP	23313552
MIRT458154	hsa-miR-377-5p	HITS-CLIP	23313552
MIRT458153	hsa-miR-6086	HITS-CLIP	23313552
MIRT458152	hsa-miR-2467-3p	HITS-CLIP	23313552
MIRT458151	hsa-miR-3612	HITS-CLIP	23313552
MIRT458150	hsa-miR-650	HITS-CLIP	23313552
MIRT458149	hsa-miR-6073	HITS-CLIP	23313552
MIRT458148	hsa-miR-142-3p	HITS-CLIP	23313552
MIRT458147	hsa-miR-921	HITS-CLIP	23313552
MIRT702181	hsa-miR-1273e	HITS-CLIP	23313552
MIRT702180	hsa-miR-2681-3p	HITS-CLIP	23313552
MIRT702179	hsa-miR-4645-5p	HITS-CLIP	23313552
MIRT702178	hsa-miR-4673	HITS-CLIP	23313552
MIRT702177	hsa-miR-215-3p	HITS-CLIP	23313552
MIRT458172	hsa-miR-6499-3p	HITS-CLIP	23313552
MIRT702176	hsa-miR-3135b	HITS-CLIP	23313552
MIRT702175	hsa-miR-504-3p	HITS-CLIP	23313552
MIRT702174	hsa-miR-122-5p	HITS-CLIP	23313552
MIRT702173	hsa-miR-3652	HITS-CLIP	23313552
MIRT702172	hsa-miR-4430	HITS-CLIP	23313552
MIRT702171	hsa-miR-4466	HITS-CLIP	23313552
MIRT702170	hsa-miR-675-5p	HITS-CLIP	23313552
MIRT702169	hsa-miR-143-5p	HITS-CLIP	23313552
MIRT702168	hsa-miR-5698	HITS-CLIP	23313552
MIRT687620	hsa-miR-6771-3p	HITS-CLIP	23313552
MIRT458176	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT687619	hsa-miR-151a-5p	HITS-CLIP	23313552
MIRT687618	hsa-miR-151b	HITS-CLIP	23313552
MIRT687617	hsa-miR-3190-5p	HITS-CLIP	23313552
MIRT687616	hsa-miR-3926	HITS-CLIP	23313552
MIRT687615	hsa-miR-3606-5p	HITS-CLIP	23313552
MIRT219209	hsa-miR-548s	HITS-CLIP	23313552
MIRT458163	hsa-miR-1910-3p	HITS-CLIP	23706177
MIRT458162	hsa-miR-6511a-5p	HITS-CLIP	23706177
MIRT458161	hsa-miR-3174	HITS-CLIP	23706177
MIRT458159	hsa-miR-4257	HITS-CLIP	23706177
MIRT458160	hsa-miR-1247-3p	HITS-CLIP	23706177
MIRT681419	hsa-miR-5186	HITS-CLIP	23706177
MIRT458158	hsa-miR-3160-3p	HITS-CLIP	23706177
MIRT458157	hsa-miR-558	HITS-CLIP	23706177
MIRT458155	hsa-miR-4487	HITS-CLIP	23706177
MIRT458156	hsa-miR-1827	HITS-CLIP	23706177
MIRT458154	hsa-miR-377-5p	HITS-CLIP	23706177
MIRT458153	hsa-miR-6086	HITS-CLIP	23706177
MIRT458152	hsa-miR-2467-3p	HITS-CLIP	23706177
MIRT458151	hsa-miR-3612	HITS-CLIP	23706177
MIRT458150	hsa-miR-650	HITS-CLIP	23706177
MIRT458149	hsa-miR-6073	HITS-CLIP	23706177
MIRT458148	hsa-miR-142-3p	HITS-CLIP	23706177
MIRT458147	hsa-miR-921	HITS-CLIP	23706177
MIRT670506	hsa-miR-4787-5p	HITS-CLIP	23824327
MIRT670505	hsa-miR-4284	HITS-CLIP	23824327
MIRT670504	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT670503	hsa-miR-3180	HITS-CLIP	23824327
MIRT670502	hsa-miR-3180-3p	HITS-CLIP	23824327
MIRT670501	hsa-miR-3196	HITS-CLIP	23824327
MIRT670500	hsa-miR-6816-5p	HITS-CLIP	23824327
MIRT670499	hsa-miR-1237-5p	HITS-CLIP	23824327
MIRT670498	hsa-miR-4488	HITS-CLIP	23824327
MIRT670497	hsa-miR-4697-5p	HITS-CLIP	23824327
MIRT670496	hsa-miR-7977	HITS-CLIP	23824327
MIRT458177	hsa-miR-508-5p	PAR-CLIP	21572407
MIRT458176	hsa-miR-6849-3p	PAR-CLIP	21572407
MIRT458175	hsa-miR-6742-3p	PAR-CLIP	21572407
MIRT458174	hsa-miR-766-3p	PAR-CLIP	21572407
MIRT458173	hsa-miR-4793-3p	PAR-CLIP	21572407
MIRT542118	hsa-miR-6776-5p	PAR-CLIP	21572407
MIRT458171	hsa-miR-661	PAR-CLIP	21572407
MIRT542117	hsa-miR-542-3p	PAR-CLIP	21572407
MIRT458170	hsa-miR-6512-3p	PAR-CLIP	21572407
MIRT458169	hsa-miR-6720-5p	PAR-CLIP	21572407
MIRT458166	hsa-miR-7703	PAR-CLIP	21572407
MIRT542116	hsa-miR-1262	PAR-CLIP	21572407
MIRT542115	hsa-miR-4701-3p	PAR-CLIP	21572407
MIRT542114	hsa-miR-6736-5p	PAR-CLIP	21572407
MIRT458164	hsa-miR-1273g-3p	PAR-CLIP	21572407
MIRT495154	hsa-miR-1224-3p	PAR-CLIP	23708386
MIRT495153	hsa-miR-4286	PAR-CLIP	23708386
MIRT495152	hsa-miR-377-3p	PAR-CLIP	23708386
MIRT458177	hsa-miR-508-5p	PAR-CLIP	23592263
MIRT458176	hsa-miR-6849-3p	PAR-CLIP	23592263
MIRT458175	hsa-miR-6742-3p	PAR-CLIP	23592263
MIRT458174	hsa-miR-766-3p	PAR-CLIP	23592263
MIRT458173	hsa-miR-4793-3p	PAR-CLIP	23592263
MIRT458172	hsa-miR-6499-3p	PAR-CLIP	23592263
MIRT458171	hsa-miR-661	PAR-CLIP	23592263
MIRT458170	hsa-miR-6512-3p	PAR-CLIP	23592263
MIRT458169	hsa-miR-6720-5p	PAR-CLIP	23592263
MIRT458168	hsa-miR-6807-5p	PAR-CLIP	23592263
MIRT458166	hsa-miR-7703	PAR-CLIP	23592263
MIRT458167	hsa-miR-455-3p	PAR-CLIP	23592263
MIRT458165	hsa-miR-6516-5p	PAR-CLIP	23592263
MIRT458164	hsa-miR-1273g-3p	PAR-CLIP	23592263
MIRT458163	hsa-miR-1910-3p	PAR-CLIP	23592263
MIRT458162	hsa-miR-6511a-5p	PAR-CLIP	23592263
MIRT458161	hsa-miR-3174	PAR-CLIP	23592263
MIRT458159	hsa-miR-4257	PAR-CLIP	23592263
MIRT458160	hsa-miR-1247-3p	PAR-CLIP	23592263
MIRT458158	hsa-miR-3160-3p	PAR-CLIP	23592263
MIRT458157	hsa-miR-558	PAR-CLIP	23592263
MIRT458155	hsa-miR-4487	PAR-CLIP	23592263
MIRT458156	hsa-miR-1827	PAR-CLIP	23592263
MIRT458154	hsa-miR-377-5p	PAR-CLIP	23592263
MIRT458153	hsa-miR-6086	PAR-CLIP	23592263
MIRT458152	hsa-miR-2467-3p	PAR-CLIP	23592263
MIRT458151	hsa-miR-3612	PAR-CLIP	23592263
MIRT458150	hsa-miR-650	PAR-CLIP	23592263
MIRT458149	hsa-miR-6073	PAR-CLIP	23592263
MIRT458148	hsa-miR-142-3p	PAR-CLIP	23592263
MIRT458147	hsa-miR-921	PAR-CLIP	23592263
MIRT1123782	hsa-miR-3122	CLIP-seq
MIRT1123783	hsa-miR-3165	CLIP-seq
MIRT1123784	hsa-miR-3614-5p	CLIP-seq
MIRT1123785	hsa-miR-3665	CLIP-seq
MIRT1123786	hsa-miR-3689a-3p	CLIP-seq
MIRT1123787	hsa-miR-3689c	CLIP-seq
MIRT1123788	hsa-miR-3913-5p	CLIP-seq
MIRT1123789	hsa-miR-3929	CLIP-seq
MIRT1123790	hsa-miR-4419b	CLIP-seq
MIRT1123791	hsa-miR-4436a	CLIP-seq
MIRT1123792	hsa-miR-4478	CLIP-seq
MIRT1123793	hsa-miR-4649-3p	CLIP-seq
MIRT1123794	hsa-miR-4728-5p	CLIP-seq
MIRT1123795	hsa-miR-4736	CLIP-seq
MIRT1123796	hsa-miR-4786-5p	CLIP-seq
MIRT1123797	hsa-miR-485-5p	CLIP-seq
MIRT1123798	hsa-miR-940	CLIP-seq
MIRT1123799	hsa-miR-1225-3p	CLIP-seq
MIRT1123800	hsa-miR-323-5p	CLIP-seq
MIRT1123801	hsa-miR-3681	CLIP-seq
MIRT1123802	hsa-miR-3691-5p	CLIP-seq
MIRT1123803	hsa-miR-371-5p	CLIP-seq
MIRT1123804	hsa-miR-371b-5p	CLIP-seq
MIRT1123805	hsa-miR-3943	CLIP-seq
MIRT1123806	hsa-miR-4281	CLIP-seq
MIRT1123807	hsa-miR-4292	CLIP-seq
MIRT1123808	hsa-miR-4308	CLIP-seq
MIRT1123809	hsa-miR-4693-3p	CLIP-seq
MIRT1123810	hsa-miR-4728-3p	CLIP-seq
MIRT1123811	hsa-miR-493	CLIP-seq
MIRT2035005	hsa-miR-134	CLIP-seq
MIRT2035006	hsa-miR-3118	CLIP-seq
MIRT2035007	hsa-miR-3164	CLIP-seq
MIRT2035008	hsa-miR-4501	CLIP-seq
MIRT2035009	hsa-miR-570	CLIP-seq
MIRT2265438	hsa-miR-188-3p	CLIP-seq
MIRT2265439	hsa-miR-1909	CLIP-seq
MIRT2265440	hsa-miR-361-5p	CLIP-seq
MIRT1123791	hsa-miR-4436a	CLIP-seq
MIRT2265441	hsa-miR-4514	CLIP-seq
MIRT2265442	hsa-miR-4692	CLIP-seq
MIRT2265443	hsa-miR-4700-3p	CLIP-seq
MIRT2265444	hsa-miR-4778-5p	CLIP-seq
MIRT2265445	hsa-miR-532-3p	CLIP-seq
MIRT2265446	hsa-miR-885-3p	CLIP-seq
MIRT2390421	hsa-miR-1228	CLIP-seq
MIRT2390422	hsa-miR-128	CLIP-seq
MIRT1123782	hsa-miR-3122	CLIP-seq
MIRT1123783	hsa-miR-3165	CLIP-seq
MIRT1123785	hsa-miR-3665	CLIP-seq
MIRT1123786	hsa-miR-3689a-3p	CLIP-seq
MIRT1123787	hsa-miR-3689c	CLIP-seq
MIRT2390423	hsa-miR-377	CLIP-seq
MIRT1123788	hsa-miR-3913-5p	CLIP-seq
MIRT1123789	hsa-miR-3929	CLIP-seq
MIRT1123790	hsa-miR-4419b	CLIP-seq
MIRT1123791	hsa-miR-4436a	CLIP-seq
MIRT1123792	hsa-miR-4478	CLIP-seq
MIRT1123793	hsa-miR-4649-3p	CLIP-seq
MIRT1123794	hsa-miR-4728-5p	CLIP-seq
MIRT1123795	hsa-miR-4736	CLIP-seq
MIRT1123797	hsa-miR-485-5p	CLIP-seq
MIRT1123798	hsa-miR-940	CLIP-seq
MIRT2390421	hsa-miR-1228	CLIP-seq
MIRT1123782	hsa-miR-3122	CLIP-seq
MIRT1123783	hsa-miR-3165	CLIP-seq
MIRT1123784	hsa-miR-3614-5p	CLIP-seq
MIRT1123785	hsa-miR-3665	CLIP-seq
MIRT1123786	hsa-miR-3689a-3p	CLIP-seq
MIRT1123787	hsa-miR-3689c	CLIP-seq
MIRT1123788	hsa-miR-3913-5p	CLIP-seq
MIRT1123789	hsa-miR-3929	CLIP-seq
MIRT1123790	hsa-miR-4419b	CLIP-seq
MIRT1123791	hsa-miR-4436a	CLIP-seq
MIRT1123792	hsa-miR-4478	CLIP-seq
MIRT1123793	hsa-miR-4649-3p	CLIP-seq
MIRT1123794	hsa-miR-4728-5p	CLIP-seq
MIRT1123795	hsa-miR-4736	CLIP-seq
MIRT1123797	hsa-miR-485-5p	CLIP-seq
MIRT1123798	hsa-miR-940	CLIP-seq
MIRT2390421	hsa-miR-1228	CLIP-seq
MIRT1123782	hsa-miR-3122	CLIP-seq
MIRT1123783	hsa-miR-3165	CLIP-seq
MIRT1123784	hsa-miR-3614-5p	CLIP-seq
MIRT1123785	hsa-miR-3665	CLIP-seq
MIRT1123786	hsa-miR-3689a-3p	CLIP-seq
MIRT1123787	hsa-miR-3689c	CLIP-seq
MIRT1123788	hsa-miR-3913-5p	CLIP-seq
MIRT1123789	hsa-miR-3929	CLIP-seq
MIRT1123790	hsa-miR-4419b	CLIP-seq
MIRT1123792	hsa-miR-4478	CLIP-seq
MIRT1123793	hsa-miR-4649-3p	CLIP-seq
MIRT1123794	hsa-miR-4728-5p	CLIP-seq
MIRT1123795	hsa-miR-4736	CLIP-seq
MIRT1123797	hsa-miR-485-5p	CLIP-seq
MIRT1123798	hsa-miR-940	CLIP-seq
MIRT1123799	hsa-miR-1225-3p	CLIP-seq
MIRT2564639	hsa-miR-1226	CLIP-seq
MIRT2564640	hsa-miR-1250	CLIP-seq
MIRT2035005	hsa-miR-134	CLIP-seq
MIRT2564641	hsa-miR-141	CLIP-seq
MIRT2265438	hsa-miR-188-3p	CLIP-seq
MIRT2564642	hsa-miR-1910	CLIP-seq
MIRT2564643	hsa-miR-200a	CLIP-seq
MIRT2564644	hsa-miR-299-5p	CLIP-seq
MIRT2035006	hsa-miR-3118	CLIP-seq
MIRT1123782	hsa-miR-3122	CLIP-seq
MIRT2564645	hsa-miR-3127-5p	CLIP-seq
MIRT2035007	hsa-miR-3164	CLIP-seq
MIRT2564646	hsa-miR-3182	CLIP-seq
MIRT2564647	hsa-miR-3189-5p	CLIP-seq
MIRT2564648	hsa-miR-320e	CLIP-seq
MIRT2564649	hsa-miR-338-3p	CLIP-seq
MIRT2265440	hsa-miR-361-5p	CLIP-seq
MIRT1123786	hsa-miR-3689a-3p	CLIP-seq
MIRT1123787	hsa-miR-3689c	CLIP-seq
MIRT1123803	hsa-miR-371-5p	CLIP-seq
MIRT1123804	hsa-miR-371b-5p	CLIP-seq
MIRT1123788	hsa-miR-3913-5p	CLIP-seq
MIRT2564650	hsa-miR-3925-3p	CLIP-seq
MIRT1123805	hsa-miR-3943	CLIP-seq
MIRT2564651	hsa-miR-4274	CLIP-seq
MIRT2564652	hsa-miR-4300	CLIP-seq
MIRT1123791	hsa-miR-4436a	CLIP-seq
MIRT2035008	hsa-miR-4501	CLIP-seq
MIRT2265441	hsa-miR-4514	CLIP-seq
MIRT2265442	hsa-miR-4692	CLIP-seq
MIRT2265443	hsa-miR-4700-3p	CLIP-seq
MIRT2564653	hsa-miR-4758-3p	CLIP-seq
MIRT2564654	hsa-miR-4772-3p	CLIP-seq
MIRT2564655	hsa-miR-5096	CLIP-seq
MIRT2564656	hsa-miR-511	CLIP-seq
MIRT2564657	hsa-miR-515-5p	CLIP-seq
MIRT2265445	hsa-miR-532-3p	CLIP-seq
MIRT2564658	hsa-miR-596	CLIP-seq
MIRT2564659	hsa-miR-764	CLIP-seq
MIRT2564660	hsa-miR-766	CLIP-seq
MIRT2265446	hsa-miR-885-3p	CLIP-seq
MIRT2564661	hsa-miR-920	CLIP-seq
MIRT2564639	hsa-miR-1226	CLIP-seq
MIRT2564640	hsa-miR-1250	CLIP-seq
MIRT2035005	hsa-miR-134	CLIP-seq
MIRT2564641	hsa-miR-141	CLIP-seq
MIRT2265438	hsa-miR-188-3p	CLIP-seq
MIRT2564642	hsa-miR-1910	CLIP-seq
MIRT2564643	hsa-miR-200a	CLIP-seq
MIRT2564644	hsa-miR-299-5p	CLIP-seq
MIRT2035006	hsa-miR-3118	CLIP-seq
MIRT1123782	hsa-miR-3122	CLIP-seq
MIRT2035007	hsa-miR-3164	CLIP-seq
MIRT2564646	hsa-miR-3182	CLIP-seq
MIRT2564648	hsa-miR-320e	CLIP-seq
MIRT2265440	hsa-miR-361-5p	CLIP-seq
MIRT1123786	hsa-miR-3689a-3p	CLIP-seq
MIRT1123787	hsa-miR-3689c	CLIP-seq
MIRT1123788	hsa-miR-3913-5p	CLIP-seq
MIRT2564650	hsa-miR-3925-3p	CLIP-seq
MIRT2564651	hsa-miR-4274	CLIP-seq
MIRT2564652	hsa-miR-4300	CLIP-seq
MIRT1123791	hsa-miR-4436a	CLIP-seq
MIRT2035008	hsa-miR-4501	CLIP-seq
MIRT2265441	hsa-miR-4514	CLIP-seq
MIRT2265442	hsa-miR-4692	CLIP-seq
MIRT2265443	hsa-miR-4700-3p	CLIP-seq
MIRT2564654	hsa-miR-4772-3p	CLIP-seq
MIRT2564655	hsa-miR-5096	CLIP-seq
MIRT2564656	hsa-miR-511	CLIP-seq
MIRT2564657	hsa-miR-515-5p	CLIP-seq
MIRT2265445	hsa-miR-532-3p	CLIP-seq
MIRT2564658	hsa-miR-596	CLIP-seq
MIRT2564659	hsa-miR-764	CLIP-seq
MIRT2564660	hsa-miR-766	CLIP-seq
MIRT2265446	hsa-miR-885-3p	CLIP-seq
MIRT2564661	hsa-miR-920	CLIP-seq

Show/Hide all(22)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005198	Function	Structural molecule activity	IDA	28634302
GO:0005515	Function	Protein binding	IPI	18650437, 26342079, 27499296, 29097656, 31664822, 33961781
GO:0005634	Component	Nucleus	IDA	23593335
GO:0005634	Component	Nucleus	IEA
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IBA
GO:0005739	Component	Mitochondrion	IDA	17331979, 23593335
GO:0005739	Component	Mitochondrion	IEA
GO:0005739	Component	Mitochondrion	NAS	27519411
GO:0005759	Component	Mitochondrial matrix	TAS
GO:0016226	Process	Iron-sulfur cluster assembly	IBA
GO:0016226	Process	Iron-sulfur cluster assembly	IEA
GO:0016226	Process	Iron-sulfur cluster assembly	NAS	29097656
GO:0016604	Component	Nuclear body	IDA
GO:0042803	Function	Protein homodimerization activity	IDA	29097656, 34824239
GO:0044571	Process	[2Fe-2S] cluster assembly	IDA	17331979, 31664822
GO:0044572	Process	[4Fe-4S] cluster assembly	IEA
GO:0044572	Process	[4Fe-4S] cluster assembly	ISS
GO:0099128	Component	Mitochondrial [2Fe-2S] assembly complex	IDA	21298097, 31101807
GO:0099128	Component	Mitochondrial [2Fe-2S] assembly complex	IEA
GO:1990221	Component	L-cysteine desulfurase complex	IBA
GO:1990229	Component	Iron-sulfur cluster assembly complex	NAS	29097656

MIM	HGNC	e!Ensembl
613311	21365	ENSG00000214113

Protein

UniProt ID

Q9HD34

Protein name

LYR motif-containing protein 4

Protein function

Stabilizing factor, of the core iron-sulfur cluster (ISC) assembly complex, that regulates, in association with NDUFAB1, the stability and the cysteine desulfurase activity of NFS1 and participates in the [2Fe-2S] clusters assembly on the scaffo

PDB

5USR , 5WGB , 5WKP , 5WLW , 6NZU , 6ODD , 6UXE , 6W1D , 6WI2 , 6WIH , 7RTK , 8PK8 , 8PK9 , 8PKA , 8RMC , 8RMD , 8RME , 8RMF , 8RMG , 8TVT

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF05347	Complex1_LYR	7 → 65	Complex 1 protein (LYR family)	Family

Tissue specificity

TISSUE SPECIFICITY: Reduced mRNA levels in Friedreich ataxia patients. {ECO:0000269|PubMed:17331979}.

Sequence

MAASSRAQVLSLYRAMLRESKRFSAYNYRTYAVRRIRDAFRENKNVKDPVEIQTLVNKAK
RDLGVIRRQVHIGQLYSTDKLIIENRDMPRT

Sequence length

Interactions

View interactions

	Reactome
			Mitochondrial iron-sulfur cluster biogenesis

Show/Hide Causal Diseases (1)

Disease merge term	Disease name	dbSNP ID	References
Causal Diseases caused by PATHOGENIC or LIKELY PATHOGENIC variants from ClinVar only
Combined Oxidative Phosphorylation Deficiency	combined oxidative phosphorylation deficiency 19	rs587777218	N/A

Show/Hide Unknown Diseases (1)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Lactic Acidosis	severe neonatal lactic acidosis due to NFS1-ISD11 complex deficiency	N/A	N/A	GenCC

Show/Hide Text Mining Associations (7)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Colitis Ulcerative	Associate	19068216
Crohn Disease	Associate	19068216
Cytochrome c Oxidase Deficiency	Associate	23814038
Friedreich Ataxia	Associate	21671584
Glioma	Associate	37810780
Mitochondrial complex I deficiency	Associate	23814038
Mitochondrial Diseases	Associate	23814038, 26342079

LYRM4 (LYR motif containing 4)