Gene Gene information from NCBI Gene database.
Entrez ID 57125
Gene name Plexin domain containing 1
Gene symbol PLXDC1
Synonyms (NCBI Gene)
TEM3TEM7
Chromosome 17
Chromosome location 17q12
miRNA miRNA information provided by mirtarbase database.
509
miRTarBase ID miRNA Experiments Reference
MIRT611370 hsa-miR-4524b-3p HITS-CLIP 19536157
MIRT611369 hsa-miR-5091 HITS-CLIP 19536157
MIRT611368 hsa-miR-5739 HITS-CLIP 19536157
MIRT611367 hsa-miR-4524a-3p HITS-CLIP 19536157
MIRT611370 hsa-miR-4524b-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
14
GO ID Ontology Definition Evidence Reference
GO:0001525 Process Angiogenesis NAS 10947988
GO:0005515 Function Protein binding IPI 15574754
GO:0005576 Component Extracellular region IEA
GO:0005615 Component Extracellular space NAS 15574754
GO:0005737 Component Cytoplasm IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
606826 20945 ENSG00000161381
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8IUK5
Protein name Plexin domain-containing protein 1 (Tumor endothelial marker 3) (Tumor endothelial marker 7)
Protein function Plays a critical role in endothelial cell capillary morphogenesis.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01437 PSI 303 348 Plexin repeat Family
Tissue specificity TISSUE SPECIFICITY: Detected in urine (at protein level) (PubMed:25326458, PubMed:36213313, PubMed:37453717). Detected in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brai
Sequence
MRGELWLLVLVLREAARALSPQPGAGHDEGPGSGWAAKGTVRGWNRRARESPGHVSEPDR
TQLSQDLGGGTLAMDTLPDNRTRVVEDNHSYYVSRLYGPSEPHSRELWVDVAEANRSQVK
IHTILSNTHRQASRVVLSFDFPFYGHPLRQITIATGGFIFMGDVIHRMLTATQYVAPLMA
NFNPGYSDNSTVVYFDNGTVFVVQWDHVYLQGWEDKGSFTFQAALHHDGRIVFAYKEIPM
SVPEISSSQHPVKTGLSDAFMILNPSPDVPESRRRSIFEYHRIELDPSKVTSMSAVEFTP
LPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWMDYGCAQEAEGRMCEDFQ
DEDHDSASPDTSFSPYDGDLTTTSSSLFIDSLTTEDDTKLNPYAGGDGLQNNLSPKTKGT
PVHLGTIVGIVLAVLLVAAIILAGIYINGHPTSNAALFFIERRPHHWPAMKFRSHPDHST
YAEVEPSGHEKEGFMEAEQC
Sequence length 500
Interactions View interactions