GOPC (golgi associated PDZ and coiled-coil motif containing)

Gene

• Entrez ID: 57120
• Gene name: Golgi associated PDZ and coiled-coil motif containing
• Gene symbol: GOPC
• Synonyms (NCBI Gene): CAL, FIG, GOPC1, PIST, dJ94G16.2
• Chromosome: 6
• Chromosome location: 6q22.1
• Summary: This gene encodes a Golgi protein with a PDZ domain. The PDZ domain is globular and proteins which contain them bind other proteins through short motifs near the C-termini. Mice which are deficient in the orthologous protein have globozoospermia and are i

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT020115	hsa-miR-130b-3p	Sequencing	20371350
MIRT027025	hsa-miR-103a-3p	Sequencing	20371350
MIRT1027357	hsa-miR-140-3p	CLIP-seq
MIRT1027358	hsa-miR-219-2-3p	CLIP-seq
MIRT1027359	hsa-miR-23a	CLIP-seq
MIRT1027360	hsa-miR-23b	CLIP-seq
MIRT1027361	hsa-miR-23c	CLIP-seq
MIRT1027362	hsa-miR-3143	CLIP-seq
MIRT1027363	hsa-miR-33a	CLIP-seq
MIRT1027364	hsa-miR-33b	CLIP-seq
MIRT1027365	hsa-miR-3689a-5p	CLIP-seq
MIRT1027366	hsa-miR-3689b	CLIP-seq
MIRT1027367	hsa-miR-3689e	CLIP-seq
MIRT1027368	hsa-miR-3689f	CLIP-seq
MIRT1027369	hsa-miR-4461	CLIP-seq
MIRT1027370	hsa-miR-4717-3p	CLIP-seq
MIRT1027371	hsa-miR-4789-3p	CLIP-seq
MIRT1027372	hsa-miR-4789-5p	CLIP-seq
MIRT1027373	hsa-miR-491-3p	CLIP-seq
MIRT1027374	hsa-miR-520d-5p	CLIP-seq
MIRT1027375	hsa-miR-524-5p	CLIP-seq
MIRT1027376	hsa-miR-570	CLIP-seq
MIRT1027377	hsa-miR-580	CLIP-seq
MIRT1027378	hsa-miR-584	CLIP-seq
MIRT1027379	hsa-miR-586	CLIP-seq
MIRT1027380	hsa-miR-595	CLIP-seq
MIRT1027381	hsa-miR-601	CLIP-seq
MIRT1027382	hsa-miR-609	CLIP-seq
MIRT1027383	hsa-miR-877	CLIP-seq
MIRT1027384	hsa-miR-142-5p	CLIP-seq
MIRT1027385	hsa-miR-3121-3p	CLIP-seq
MIRT1027386	hsa-miR-548a-5p	CLIP-seq
MIRT1027387	hsa-miR-548aa	CLIP-seq
MIRT1027388	hsa-miR-548ab	CLIP-seq
MIRT1027389	hsa-miR-548ak	CLIP-seq
MIRT1027390	hsa-miR-548b-5p	CLIP-seq
MIRT1027391	hsa-miR-548c-5p	CLIP-seq
MIRT1027392	hsa-miR-548d-5p	CLIP-seq
MIRT1027393	hsa-miR-548h	CLIP-seq
MIRT1027394	hsa-miR-548i	CLIP-seq
MIRT1027395	hsa-miR-548j	CLIP-seq
MIRT1027396	hsa-miR-548k	CLIP-seq
MIRT1027397	hsa-miR-548l	CLIP-seq
MIRT1027398	hsa-miR-548p	CLIP-seq
MIRT1027399	hsa-miR-548w	CLIP-seq
MIRT1027400	hsa-miR-548y	CLIP-seq
MIRT1027401	hsa-miR-559	CLIP-seq
MIRT1920461	hsa-miR-1279	CLIP-seq
MIRT1920462	hsa-miR-3140-3p	CLIP-seq
MIRT1920463	hsa-miR-587	CLIP-seq
MIRT1920464	hsa-miR-664	CLIP-seq
MIRT1920461	hsa-miR-1279	CLIP-seq
MIRT1920462	hsa-miR-3140-3p	CLIP-seq
MIRT1920463	hsa-miR-587	CLIP-seq
MIRT1920464	hsa-miR-664	CLIP-seq
MIRT2004743	hsa-miR-1231	CLIP-seq
MIRT1027357	hsa-miR-140-3p	CLIP-seq
MIRT2004744	hsa-miR-3655	CLIP-seq
MIRT2004745	hsa-miR-409-3p	CLIP-seq
MIRT2004746	hsa-miR-4288	CLIP-seq
MIRT2004747	hsa-miR-495	CLIP-seq
MIRT2004748	hsa-miR-519a	CLIP-seq
MIRT2004749	hsa-miR-519b-3p	CLIP-seq
MIRT2004750	hsa-miR-519c-3p	CLIP-seq
MIRT1027398	hsa-miR-548p	CLIP-seq
MIRT2004751	hsa-miR-632	CLIP-seq
MIRT1027362	hsa-miR-3143	CLIP-seq
MIRT1027365	hsa-miR-3689a-5p	CLIP-seq
MIRT1027366	hsa-miR-3689b	CLIP-seq
MIRT1027367	hsa-miR-3689e	CLIP-seq
MIRT1027368	hsa-miR-3689f	CLIP-seq
MIRT1027374	hsa-miR-520d-5p	CLIP-seq
MIRT1027375	hsa-miR-524-5p	CLIP-seq
MIRT2237505	hsa-miR-128	CLIP-seq
MIRT1027357	hsa-miR-140-3p	CLIP-seq
MIRT2237506	hsa-miR-1910	CLIP-seq
MIRT1027362	hsa-miR-3143	CLIP-seq
MIRT2237507	hsa-miR-3591-3p	CLIP-seq
MIRT2237508	hsa-miR-361-5p	CLIP-seq
MIRT1027365	hsa-miR-3689a-5p	CLIP-seq
MIRT1027366	hsa-miR-3689b	CLIP-seq
MIRT1027367	hsa-miR-3689e	CLIP-seq
MIRT1027368	hsa-miR-3689f	CLIP-seq
MIRT2237509	hsa-miR-377	CLIP-seq
MIRT2237510	hsa-miR-4325	CLIP-seq
MIRT2237511	hsa-miR-455-3p	CLIP-seq
MIRT1027374	hsa-miR-520d-5p	CLIP-seq
MIRT1027375	hsa-miR-524-5p	CLIP-seq
MIRT1027376	hsa-miR-570	CLIP-seq
MIRT2237512	hsa-miR-885-5p	CLIP-seq
MIRT2237505	hsa-miR-128	CLIP-seq
MIRT1027357	hsa-miR-140-3p	CLIP-seq
MIRT1027362	hsa-miR-3143	CLIP-seq
MIRT2388574	hsa-miR-3182	CLIP-seq
MIRT2388575	hsa-miR-4766-5p	CLIP-seq
MIRT2388576	hsa-miR-543	CLIP-seq
MIRT2541246	hsa-miR-1183	CLIP-seq
MIRT2541247	hsa-miR-1224-3p	CLIP-seq
MIRT2541248	hsa-miR-1229	CLIP-seq
MIRT2541249	hsa-miR-1250	CLIP-seq
MIRT1920461	hsa-miR-1279	CLIP-seq
MIRT2237505	hsa-miR-128	CLIP-seq
MIRT2541250	hsa-miR-129-5p	CLIP-seq
MIRT2541251	hsa-miR-1302	CLIP-seq
MIRT2541252	hsa-miR-1303	CLIP-seq
MIRT1027357	hsa-miR-140-3p	CLIP-seq
MIRT2541253	hsa-miR-145	CLIP-seq
MIRT2541254	hsa-miR-197	CLIP-seq
MIRT2541255	hsa-miR-2110	CLIP-seq
MIRT2541256	hsa-miR-2113	CLIP-seq
MIRT2541257	hsa-miR-221	CLIP-seq
MIRT2541258	hsa-miR-222	CLIP-seq
MIRT2541259	hsa-miR-2681	CLIP-seq
MIRT2541260	hsa-miR-27a	CLIP-seq
MIRT2541261	hsa-miR-27b	CLIP-seq
MIRT2541262	hsa-miR-29a	CLIP-seq
MIRT2541263	hsa-miR-29b	CLIP-seq
MIRT2541264	hsa-miR-29c	CLIP-seq
MIRT2541265	hsa-miR-3065-3p	CLIP-seq
MIRT2541266	hsa-miR-3120-3p	CLIP-seq
MIRT2541267	hsa-miR-3123	CLIP-seq
MIRT2541268	hsa-miR-3138	CLIP-seq
MIRT1920462	hsa-miR-3140-3p	CLIP-seq
MIRT2541269	hsa-miR-3148	CLIP-seq
MIRT2541270	hsa-miR-3163	CLIP-seq
MIRT2541271	hsa-miR-3200-5p	CLIP-seq
MIRT2541272	hsa-miR-340	CLIP-seq
MIRT2237507	hsa-miR-3591-3p	CLIP-seq
MIRT2541273	hsa-miR-3616-5p	CLIP-seq
MIRT2541274	hsa-miR-3647-5p	CLIP-seq
MIRT2541275	hsa-miR-3661	CLIP-seq
MIRT2541276	hsa-miR-3668	CLIP-seq
MIRT2541277	hsa-miR-3671	CLIP-seq
MIRT2541278	hsa-miR-3678-3p	CLIP-seq
MIRT2541279	hsa-miR-3687	CLIP-seq
MIRT2541280	hsa-miR-371-5p	CLIP-seq
MIRT2541281	hsa-miR-371b-5p	CLIP-seq
MIRT2237509	hsa-miR-377	CLIP-seq
MIRT2541282	hsa-miR-3907	CLIP-seq
MIRT2541283	hsa-miR-3941	CLIP-seq
MIRT2004745	hsa-miR-409-3p	CLIP-seq
MIRT2541284	hsa-miR-4261	CLIP-seq
MIRT2541285	hsa-miR-4263	CLIP-seq
MIRT2541286	hsa-miR-4271	CLIP-seq
MIRT2541287	hsa-miR-4275	CLIP-seq
MIRT2541288	hsa-miR-4282	CLIP-seq
MIRT2541289	hsa-miR-4298	CLIP-seq
MIRT2541290	hsa-miR-4303	CLIP-seq
MIRT2541291	hsa-miR-4418	CLIP-seq
MIRT2541292	hsa-miR-4442	CLIP-seq
MIRT2541293	hsa-miR-4457	CLIP-seq
MIRT2541294	hsa-miR-4474-5p	CLIP-seq
MIRT2541295	hsa-miR-4496	CLIP-seq
MIRT2541296	hsa-miR-4527	CLIP-seq
MIRT2541297	hsa-miR-4635	CLIP-seq
MIRT2541298	hsa-miR-4643	CLIP-seq
MIRT2541299	hsa-miR-4653-3p	CLIP-seq
MIRT2541300	hsa-miR-466	CLIP-seq
MIRT2541301	hsa-miR-4668-3p	CLIP-seq
MIRT2541302	hsa-miR-4668-5p	CLIP-seq
MIRT2541303	hsa-miR-4670-3p	CLIP-seq
MIRT2541304	hsa-miR-4672	CLIP-seq
MIRT2541305	hsa-miR-4693-5p	CLIP-seq
MIRT2541306	hsa-miR-4695-3p	CLIP-seq
MIRT2541307	hsa-miR-4698	CLIP-seq
MIRT2541308	hsa-miR-4699-3p	CLIP-seq
MIRT1027370	hsa-miR-4717-3p	CLIP-seq
MIRT2541309	hsa-miR-4719	CLIP-seq
MIRT2541310	hsa-miR-4725-3p	CLIP-seq
MIRT2541311	hsa-miR-4729	CLIP-seq
MIRT2541312	hsa-miR-4738-3p	CLIP-seq
MIRT2541313	hsa-miR-4752	CLIP-seq
MIRT2541314	hsa-miR-4756-3p	CLIP-seq
MIRT2541315	hsa-miR-4760-5p	CLIP-seq
MIRT1027371	hsa-miR-4789-3p	CLIP-seq
MIRT2541316	hsa-miR-4799-5p	CLIP-seq
MIRT2541317	hsa-miR-4800-5p	CLIP-seq
MIRT2541318	hsa-miR-491-5p	CLIP-seq
MIRT2004747	hsa-miR-495	CLIP-seq
MIRT2541319	hsa-miR-509-3-5p	CLIP-seq
MIRT2541320	hsa-miR-509-5p	CLIP-seq
MIRT2541321	hsa-miR-511	CLIP-seq
MIRT2541322	hsa-miR-513b	CLIP-seq
MIRT2541323	hsa-miR-513c	CLIP-seq
MIRT2541324	hsa-miR-514b-5p	CLIP-seq
MIRT2541325	hsa-miR-545	CLIP-seq
MIRT2541326	hsa-miR-548a-3p	CLIP-seq
MIRT1027387	hsa-miR-548aa	CLIP-seq
MIRT2541327	hsa-miR-548ac	CLIP-seq
MIRT2541328	hsa-miR-548c-3p	CLIP-seq
MIRT2541329	hsa-miR-548d-3p	CLIP-seq
MIRT2541330	hsa-miR-548e	CLIP-seq
MIRT2541331	hsa-miR-548f	CLIP-seq
MIRT2541332	hsa-miR-548g	CLIP-seq
MIRT1027398	hsa-miR-548p	CLIP-seq
MIRT2541333	hsa-miR-548v	CLIP-seq
MIRT2541334	hsa-miR-548z	CLIP-seq
MIRT2541335	hsa-miR-568	CLIP-seq
MIRT1027376	hsa-miR-570	CLIP-seq
MIRT2541336	hsa-miR-573	CLIP-seq
MIRT2541337	hsa-miR-576-5p	CLIP-seq
MIRT1920463	hsa-miR-587	CLIP-seq
MIRT2541338	hsa-miR-590-3p	CLIP-seq
MIRT2541339	hsa-miR-607	CLIP-seq
MIRT2541340	hsa-miR-619	CLIP-seq
MIRT2541341	hsa-miR-631	CLIP-seq
MIRT1920464	hsa-miR-664	CLIP-seq
MIRT2541342	hsa-miR-711	CLIP-seq
MIRT2541343	hsa-miR-875-3p	CLIP-seq
MIRT1027383	hsa-miR-877	CLIP-seq
MIRT2541344	hsa-miR-888	CLIP-seq
MIRT2541246	hsa-miR-1183	CLIP-seq
MIRT2541247	hsa-miR-1224-3p	CLIP-seq
MIRT2541248	hsa-miR-1229	CLIP-seq
MIRT2541249	hsa-miR-1250	CLIP-seq
MIRT2681775	hsa-miR-1267	CLIP-seq
MIRT1920461	hsa-miR-1279	CLIP-seq
MIRT2237505	hsa-miR-128	CLIP-seq
MIRT2541250	hsa-miR-129-5p	CLIP-seq
MIRT2541251	hsa-miR-1302	CLIP-seq
MIRT2681776	hsa-miR-1304	CLIP-seq
MIRT1027357	hsa-miR-140-3p	CLIP-seq
MIRT2541254	hsa-miR-197	CLIP-seq
MIRT2681777	hsa-miR-2054	CLIP-seq
MIRT2541255	hsa-miR-2110	CLIP-seq
MIRT2541256	hsa-miR-2113	CLIP-seq
MIRT2541257	hsa-miR-221	CLIP-seq
MIRT2541258	hsa-miR-222	CLIP-seq
MIRT2681778	hsa-miR-2467-5p	CLIP-seq
MIRT2541259	hsa-miR-2681	CLIP-seq
MIRT2541260	hsa-miR-27a	CLIP-seq
MIRT2541261	hsa-miR-27b	CLIP-seq
MIRT2541262	hsa-miR-29a	CLIP-seq
MIRT2541263	hsa-miR-29b	CLIP-seq
MIRT2541264	hsa-miR-29c	CLIP-seq
MIRT2541265	hsa-miR-3065-3p	CLIP-seq
MIRT2541266	hsa-miR-3120-3p	CLIP-seq
MIRT2541267	hsa-miR-3123	CLIP-seq
MIRT2541268	hsa-miR-3138	CLIP-seq
MIRT1920462	hsa-miR-3140-3p	CLIP-seq
MIRT2541269	hsa-miR-3148	CLIP-seq
MIRT2541270	hsa-miR-3163	CLIP-seq
MIRT2681779	hsa-miR-3188	CLIP-seq
MIRT2541271	hsa-miR-3200-5p	CLIP-seq
MIRT2541272	hsa-miR-340	CLIP-seq
MIRT2237507	hsa-miR-3591-3p	CLIP-seq
MIRT2541273	hsa-miR-3616-5p	CLIP-seq
MIRT2541274	hsa-miR-3647-5p	CLIP-seq
MIRT2541275	hsa-miR-3661	CLIP-seq
MIRT2541277	hsa-miR-3671	CLIP-seq
MIRT2541279	hsa-miR-3687	CLIP-seq
MIRT2541280	hsa-miR-371-5p	CLIP-seq
MIRT2541281	hsa-miR-371b-5p	CLIP-seq
MIRT2237509	hsa-miR-377	CLIP-seq
MIRT2541282	hsa-miR-3907	CLIP-seq
MIRT2541283	hsa-miR-3941	CLIP-seq
MIRT2681780	hsa-miR-3975	CLIP-seq
MIRT2004745	hsa-miR-409-3p	CLIP-seq
MIRT2541285	hsa-miR-4263	CLIP-seq
MIRT2541286	hsa-miR-4271	CLIP-seq
MIRT2541287	hsa-miR-4275	CLIP-seq
MIRT2541288	hsa-miR-4282	CLIP-seq
MIRT2541289	hsa-miR-4298	CLIP-seq
MIRT2541290	hsa-miR-4303	CLIP-seq
MIRT2541291	hsa-miR-4418	CLIP-seq
MIRT2541292	hsa-miR-4442	CLIP-seq
MIRT2541293	hsa-miR-4457	CLIP-seq
MIRT2541294	hsa-miR-4474-5p	CLIP-seq
MIRT2541295	hsa-miR-4496	CLIP-seq
MIRT2541296	hsa-miR-4527	CLIP-seq
MIRT2541297	hsa-miR-4635	CLIP-seq
MIRT2541298	hsa-miR-4643	CLIP-seq
MIRT2541299	hsa-miR-4653-3p	CLIP-seq
MIRT2541300	hsa-miR-466	CLIP-seq
MIRT2541302	hsa-miR-4668-5p	CLIP-seq
MIRT2541303	hsa-miR-4670-3p	CLIP-seq
MIRT2541304	hsa-miR-4672	CLIP-seq
MIRT2541305	hsa-miR-4693-5p	CLIP-seq
MIRT2541307	hsa-miR-4698	CLIP-seq
MIRT1027370	hsa-miR-4717-3p	CLIP-seq
MIRT2541309	hsa-miR-4719	CLIP-seq
MIRT2541310	hsa-miR-4725-3p	CLIP-seq
MIRT2541312	hsa-miR-4738-3p	CLIP-seq
MIRT2541313	hsa-miR-4752	CLIP-seq
MIRT2541314	hsa-miR-4756-3p	CLIP-seq
MIRT2541315	hsa-miR-4760-5p	CLIP-seq
MIRT1027371	hsa-miR-4789-3p	CLIP-seq
MIRT2541316	hsa-miR-4799-5p	CLIP-seq
MIRT2541317	hsa-miR-4800-5p	CLIP-seq
MIRT2681781	hsa-miR-485-3p	CLIP-seq
MIRT2681782	hsa-miR-485-5p	CLIP-seq
MIRT2541318	hsa-miR-491-5p	CLIP-seq
MIRT2004747	hsa-miR-495	CLIP-seq
MIRT2541319	hsa-miR-509-3-5p	CLIP-seq
MIRT2541320	hsa-miR-509-5p	CLIP-seq
MIRT2541321	hsa-miR-511	CLIP-seq
MIRT2541322	hsa-miR-513b	CLIP-seq
MIRT2541323	hsa-miR-513c	CLIP-seq
MIRT2541324	hsa-miR-514b-5p	CLIP-seq
MIRT2541325	hsa-miR-545	CLIP-seq
MIRT2541326	hsa-miR-548a-3p	CLIP-seq
MIRT1027387	hsa-miR-548aa	CLIP-seq
MIRT2541327	hsa-miR-548ac	CLIP-seq
MIRT2541328	hsa-miR-548c-3p	CLIP-seq
MIRT2541329	hsa-miR-548d-3p	CLIP-seq
MIRT2541330	hsa-miR-548e	CLIP-seq
MIRT2541331	hsa-miR-548f	CLIP-seq
MIRT2541332	hsa-miR-548g	CLIP-seq
MIRT1027398	hsa-miR-548p	CLIP-seq
MIRT2541333	hsa-miR-548v	CLIP-seq
MIRT2541334	hsa-miR-548z	CLIP-seq
MIRT2541335	hsa-miR-568	CLIP-seq
MIRT1027376	hsa-miR-570	CLIP-seq
MIRT2541336	hsa-miR-573	CLIP-seq
MIRT2541337	hsa-miR-576-5p	CLIP-seq
MIRT1920463	hsa-miR-587	CLIP-seq
MIRT2541339	hsa-miR-607	CLIP-seq
MIRT2541341	hsa-miR-631	CLIP-seq
MIRT1920464	hsa-miR-664	CLIP-seq
MIRT2541342	hsa-miR-711	CLIP-seq
MIRT2541343	hsa-miR-875-3p	CLIP-seq
MIRT2541344	hsa-miR-888	CLIP-seq
MIRT2681783	hsa-miR-944	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0005515	Function	Protein binding	IPI	11384996, 11707463, 12471024, 19027007, 20195357, 23818989, 25416956, 25609649, 26179146, 28360110, 28514442, 29892012, 31324722, 31515488, 32296183, 33961781, 36012204
GO:0005737	Component	Cytoplasm	IDA	11707463
GO:0005737	Component	Cytoplasm	IEA
GO:0005765	Component	Lysosomal membrane	TAS
GO:0005794	Component	Golgi apparatus	IBA
GO:0005794	Component	Golgi apparatus	IDA	11384996, 23818989
GO:0005794	Component	Golgi apparatus	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	NAS	11707463
GO:0005886	Component	Plasma membrane	TAS
GO:0006888	Process	Endoplasmic reticulum to Golgi vesicle-mediated transport	NAS	11707463
GO:0006893	Process	Golgi to plasma membrane transport	NAS	11707463
GO:0010360	Process	Negative regulation of anion channel activity	IMP	11707463
GO:0014069	Component	Postsynaptic density	IEA
GO:0015031	Process	Protein transport	IEA
GO:0016020	Component	Membrane	IBA
GO:0016020	Component	Membrane	IDA	11707463
GO:0016020	Component	Membrane	IEA
GO:0030140	Component	Trans-Golgi network transport vesicle	IBA
GO:0030140	Component	Trans-Golgi network transport vesicle	IDA	11707463
GO:0030140	Component	Trans-Golgi network transport vesicle	NAS	11384996
GO:0030425	Component	Dendrite	IEA
GO:0030660	Component	Golgi-associated vesicle membrane	TAS
GO:0032991	Component	Protein-containing complex	IDA	18468998
GO:0042802	Function	Identical protein binding	IEA
GO:0042802	Function	Identical protein binding	IPI	11707463
GO:0042995	Component	Cell projection	IEA
GO:0044325	Function	Transmembrane transporter binding	IBA
GO:0044325	Function	Transmembrane transporter binding	IPI	11707463
GO:0045176	Process	Apical protein localization	NAS	11707463
GO:0045202	Component	Synapse	IEA
GO:0140313	Function	Molecular sequestering activity	IMP	11707463
GO:2000009	Process	Negative regulation of protein localization to cell surface	IBA
GO:2000009	Process	Negative regulation of protein localization to cell surface	IMP	11707463

Other IDs

• MIM: 606845
• HGNC: 17643
• e!Ensembl: ENSG00000047932

Protein

• UniProt ID: Q9HD26
• Protein name: Golgi-associated PDZ and coiled-coil motif-containing protein (CFTR-associated ligand) (Fused in glioblastoma) (PDZ protein interacting specifically with TC10) (PIST)
• Protein function: Plays a role in intracellular protein trafficking and degradation (PubMed:11707463, PubMed:14570915, PubMed:15358775). May regulate CFTR chloride currents and acid-induced ASIC3 currents by modulating cell surface expression of both channels (By
• PDB: 2DC2, 2LOB, 4E34, 4E35, 4JOE, 4JOF, 4JOG, 4JOH, 4JOJ, 4JOK, 4JOP, 4JOR, 4K6Y, 4K72, 4K75, 4K76, 4K78, 4NMO, 4NMP, 4NMQ, 4NMR, 4NMS, 4NMT, 4NMV, 4Q6H, 4Q6S, 5IC3, 5K4F, 6OV7, 6V84, 6XNJ, 7JZO, 7JZP, 7JZQ, 7JZR
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00595	PDZ	288 → 368	PDZ domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitously expressed. {ECO:0000269|PubMed:11162552, ECO:0000269|PubMed:11384996, ECO:0000269|PubMed:11707463}.
• Sequence:

  MSAGGPCPAAAGGGPGGASCSVGAPGGVSMFRWLEVLEKEFDKAFVDVDLLLGEIDPDQA
  DITYEGRQKMTSLSSCFAQLCHKAQSVSQINHKLEAQLVDLKSELTETQAEKVVLEKEVH
  DQLLQLHSIQLQLHAKTGQSADSGTIKAKLSGPSVEELERELEANKKEKMKEAQLEAEVK
  LLRKENEALRRHIAVLQAEVYGARLAAKYLDKELAGRVQQIQLLGRDMKGPAHDKLWNQL
  EAEIHLHRHKTVIRACRGRNDLKRPMQAPPGHDQDSLKKSQGVGPIRKVLLLKEDHEGLG
  ISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDTKHKEAVTILSQQR
  GEIEFEVVYVAPEVDSDDENVEYEDESGHRYRLYLDELEGGGNPGASCKDTSGEIKVLQG
  FNKKAVTDTHENGDLGTASETPLDDGASKLDDLHTLYHKKSY

• Sequence length: 462

Pathways

Reactome:

RHO GTPases regulate CFTR trafficking