ANKMY2 (ankyrin repeat and MYND domain containing 2)

Gene

• Entrez ID: 57037
• Gene name: Ankyrin repeat and MYND domain containing 2
• Gene symbol: ANKMY2
• Synonyms (NCBI Gene): ZMYND20
• Chromosome: 7
• Chromosome location: 7p21.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT782398	hsa-miR-1286	CLIP-seq
MIRT782399	hsa-miR-3074-5p	CLIP-seq
MIRT782400	hsa-miR-3126-5p	CLIP-seq
MIRT782401	hsa-miR-370	CLIP-seq
MIRT782402	hsa-miR-375	CLIP-seq
MIRT782403	hsa-miR-4326	CLIP-seq
MIRT782404	hsa-miR-4419a	CLIP-seq
MIRT782405	hsa-miR-4510	CLIP-seq
MIRT782406	hsa-miR-4663	CLIP-seq
MIRT782407	hsa-miR-4759	CLIP-seq
MIRT782408	hsa-miR-598	CLIP-seq
MIRT1930949	hsa-miR-103a	CLIP-seq
MIRT1930950	hsa-miR-107	CLIP-seq
MIRT1930951	hsa-miR-1912	CLIP-seq
MIRT782399	hsa-miR-3074-5p	CLIP-seq
MIRT782400	hsa-miR-3126-5p	CLIP-seq
MIRT782401	hsa-miR-370	CLIP-seq
MIRT782402	hsa-miR-375	CLIP-seq
MIRT1930952	hsa-miR-3978	CLIP-seq
MIRT1930953	hsa-miR-4310	CLIP-seq
MIRT782403	hsa-miR-4326	CLIP-seq
MIRT782404	hsa-miR-4419a	CLIP-seq
MIRT782405	hsa-miR-4510	CLIP-seq
MIRT782406	hsa-miR-4663	CLIP-seq
MIRT1930954	hsa-miR-4668-3p	CLIP-seq
MIRT1930955	hsa-miR-4731-3p	CLIP-seq
MIRT1930956	hsa-miR-4801	CLIP-seq
MIRT1930957	hsa-miR-875-3p	CLIP-seq
MIRT2171490	hsa-miR-1185	CLIP-seq
MIRT2171491	hsa-miR-1909	CLIP-seq
MIRT2171492	hsa-miR-21	CLIP-seq
MIRT782399	hsa-miR-3074-5p	CLIP-seq
MIRT782400	hsa-miR-3126-5p	CLIP-seq
MIRT2171493	hsa-miR-3180-5p	CLIP-seq
MIRT2171494	hsa-miR-3605-5p	CLIP-seq
MIRT2171495	hsa-miR-3679-5p	CLIP-seq
MIRT782401	hsa-miR-370	CLIP-seq
MIRT782402	hsa-miR-375	CLIP-seq
MIRT2171496	hsa-miR-384	CLIP-seq
MIRT2171497	hsa-miR-4267	CLIP-seq
MIRT782403	hsa-miR-4326	CLIP-seq
MIRT782404	hsa-miR-4419a	CLIP-seq
MIRT782405	hsa-miR-4510	CLIP-seq
MIRT782406	hsa-miR-4663	CLIP-seq
MIRT2171498	hsa-miR-4710	CLIP-seq
MIRT2171499	hsa-miR-4769-3p	CLIP-seq
MIRT2171500	hsa-miR-586	CLIP-seq
MIRT2171501	hsa-miR-590-5p	CLIP-seq
MIRT782399	hsa-miR-3074-5p	CLIP-seq
MIRT782400	hsa-miR-3126-5p	CLIP-seq
MIRT782401	hsa-miR-370	CLIP-seq
MIRT782402	hsa-miR-375	CLIP-seq
MIRT782403	hsa-miR-4326	CLIP-seq
MIRT782404	hsa-miR-4419a	CLIP-seq
MIRT782405	hsa-miR-4510	CLIP-seq
MIRT782406	hsa-miR-4663	CLIP-seq
MIRT2474449	hsa-miR-1	CLIP-seq
MIRT2474450	hsa-miR-101	CLIP-seq
MIRT2474451	hsa-miR-1200	CLIP-seq
MIRT2474452	hsa-miR-1224-5p	CLIP-seq
MIRT2474453	hsa-miR-1228	CLIP-seq
MIRT2474454	hsa-miR-1236	CLIP-seq
MIRT2474455	hsa-miR-1273e	CLIP-seq
MIRT2474456	hsa-miR-1287	CLIP-seq
MIRT2474457	hsa-miR-1296	CLIP-seq
MIRT2474458	hsa-miR-144	CLIP-seq
MIRT2474459	hsa-miR-155	CLIP-seq
MIRT2474460	hsa-miR-204	CLIP-seq
MIRT2474461	hsa-miR-206	CLIP-seq
MIRT2474462	hsa-miR-211	CLIP-seq
MIRT2474463	hsa-miR-216b	CLIP-seq
MIRT2474464	hsa-miR-23a	CLIP-seq
MIRT2474465	hsa-miR-23b	CLIP-seq
MIRT2474466	hsa-miR-23c	CLIP-seq
MIRT2474467	hsa-miR-2909	CLIP-seq
MIRT2474468	hsa-miR-302f	CLIP-seq
MIRT782399	hsa-miR-3074-5p	CLIP-seq
MIRT2474469	hsa-miR-3135b	CLIP-seq
MIRT2474470	hsa-miR-3137	CLIP-seq
MIRT2474471	hsa-miR-3140-5p	CLIP-seq
MIRT2474472	hsa-miR-3177-5p	CLIP-seq
MIRT2171493	hsa-miR-3180-5p	CLIP-seq
MIRT2474473	hsa-miR-3194-5p	CLIP-seq
MIRT2474474	hsa-miR-3613-3p	CLIP-seq
MIRT2474475	hsa-miR-3614-3p	CLIP-seq
MIRT2474476	hsa-miR-3622b-5p	CLIP-seq
MIRT2474477	hsa-miR-3647-3p	CLIP-seq
MIRT2474478	hsa-miR-3667-3p	CLIP-seq
MIRT2474479	hsa-miR-3692	CLIP-seq
MIRT782402	hsa-miR-375	CLIP-seq
MIRT2474480	hsa-miR-376c	CLIP-seq
MIRT2171496	hsa-miR-384	CLIP-seq
MIRT2474481	hsa-miR-3924	CLIP-seq
MIRT1930952	hsa-miR-3978	CLIP-seq
MIRT2474482	hsa-miR-421	CLIP-seq
MIRT2474483	hsa-miR-4252	CLIP-seq
MIRT2474484	hsa-miR-4253	CLIP-seq
MIRT2474485	hsa-miR-4263	CLIP-seq
MIRT2171497	hsa-miR-4267	CLIP-seq
MIRT2474486	hsa-miR-4275	CLIP-seq
MIRT2474487	hsa-miR-4282	CLIP-seq
MIRT2474488	hsa-miR-4307	CLIP-seq
MIRT2474489	hsa-miR-4436b-3p	CLIP-seq
MIRT2474490	hsa-miR-4446-5p	CLIP-seq
MIRT2474491	hsa-miR-4496	CLIP-seq
MIRT2474492	hsa-miR-4528	CLIP-seq
MIRT2474493	hsa-miR-4709-5p	CLIP-seq
MIRT2171498	hsa-miR-4710	CLIP-seq
MIRT2474494	hsa-miR-4742-3p	CLIP-seq
MIRT2474495	hsa-miR-4751	CLIP-seq
MIRT2474496	hsa-miR-4755-5p	CLIP-seq
MIRT2474497	hsa-miR-4761-3p	CLIP-seq
MIRT2474498	hsa-miR-4761-5p	CLIP-seq
MIRT2474499	hsa-miR-4773	CLIP-seq
MIRT2474500	hsa-miR-486-5p	CLIP-seq
MIRT2474501	hsa-miR-494	CLIP-seq
MIRT2474502	hsa-miR-505	CLIP-seq
MIRT2474503	hsa-miR-513a-3p	CLIP-seq
MIRT2474504	hsa-miR-548ag	CLIP-seq
MIRT2474505	hsa-miR-548ai	CLIP-seq
MIRT2474506	hsa-miR-548m	CLIP-seq
MIRT2474507	hsa-miR-561	CLIP-seq
MIRT2474508	hsa-miR-564	CLIP-seq
MIRT2474509	hsa-miR-567	CLIP-seq
MIRT2474510	hsa-miR-570	CLIP-seq
MIRT2474511	hsa-miR-576-5p	CLIP-seq
MIRT2474512	hsa-miR-582-5p	CLIP-seq
MIRT2171500	hsa-miR-586	CLIP-seq
MIRT2474513	hsa-miR-587	CLIP-seq
MIRT2474514	hsa-miR-600	CLIP-seq
MIRT2474515	hsa-miR-606	CLIP-seq
MIRT2474516	hsa-miR-613	CLIP-seq
MIRT2474517	hsa-miR-623	CLIP-seq
MIRT2474518	hsa-miR-624	CLIP-seq
MIRT2474519	hsa-miR-630	CLIP-seq
MIRT2474520	hsa-miR-649	CLIP-seq
MIRT2474521	hsa-miR-873	CLIP-seq
MIRT1930957	hsa-miR-875-3p	CLIP-seq
MIRT2474449	hsa-miR-1	CLIP-seq
MIRT2474450	hsa-miR-101	CLIP-seq
MIRT2474451	hsa-miR-1200	CLIP-seq
MIRT2474452	hsa-miR-1224-5p	CLIP-seq
MIRT2474453	hsa-miR-1228	CLIP-seq
MIRT2474454	hsa-miR-1236	CLIP-seq
MIRT2474455	hsa-miR-1273e	CLIP-seq
MIRT2474456	hsa-miR-1287	CLIP-seq
MIRT2474457	hsa-miR-1296	CLIP-seq
MIRT2474458	hsa-miR-144	CLIP-seq
MIRT2675011	hsa-miR-203	CLIP-seq
MIRT2474460	hsa-miR-204	CLIP-seq
MIRT2474461	hsa-miR-206	CLIP-seq
MIRT2474462	hsa-miR-211	CLIP-seq
MIRT2474463	hsa-miR-216b	CLIP-seq
MIRT2474464	hsa-miR-23a	CLIP-seq
MIRT2474465	hsa-miR-23b	CLIP-seq
MIRT2474466	hsa-miR-23c	CLIP-seq
MIRT2474467	hsa-miR-2909	CLIP-seq
MIRT2474468	hsa-miR-302f	CLIP-seq
MIRT782399	hsa-miR-3074-5p	CLIP-seq
MIRT2474469	hsa-miR-3135b	CLIP-seq
MIRT2474470	hsa-miR-3137	CLIP-seq
MIRT2474471	hsa-miR-3140-5p	CLIP-seq
MIRT2474472	hsa-miR-3177-5p	CLIP-seq
MIRT2474473	hsa-miR-3194-5p	CLIP-seq
MIRT2474474	hsa-miR-3613-3p	CLIP-seq
MIRT2474475	hsa-miR-3614-3p	CLIP-seq
MIRT2474476	hsa-miR-3622b-5p	CLIP-seq
MIRT2474477	hsa-miR-3647-3p	CLIP-seq
MIRT2474478	hsa-miR-3667-3p	CLIP-seq
MIRT2474479	hsa-miR-3692	CLIP-seq
MIRT2474480	hsa-miR-376c	CLIP-seq
MIRT2474481	hsa-miR-3924	CLIP-seq
MIRT1930952	hsa-miR-3978	CLIP-seq
MIRT2474482	hsa-miR-421	CLIP-seq
MIRT2474483	hsa-miR-4252	CLIP-seq
MIRT2474484	hsa-miR-4253	CLIP-seq
MIRT2474485	hsa-miR-4263	CLIP-seq
MIRT2474486	hsa-miR-4275	CLIP-seq
MIRT2474487	hsa-miR-4282	CLIP-seq
MIRT2474488	hsa-miR-4307	CLIP-seq
MIRT2474489	hsa-miR-4436b-3p	CLIP-seq
MIRT2474490	hsa-miR-4446-5p	CLIP-seq
MIRT2474491	hsa-miR-4496	CLIP-seq
MIRT2474492	hsa-miR-4528	CLIP-seq
MIRT2675012	hsa-miR-4646-3p	CLIP-seq
MIRT2474493	hsa-miR-4709-5p	CLIP-seq
MIRT2171498	hsa-miR-4710	CLIP-seq
MIRT2474494	hsa-miR-4742-3p	CLIP-seq
MIRT2474495	hsa-miR-4751	CLIP-seq
MIRT2474496	hsa-miR-4755-5p	CLIP-seq
MIRT2474497	hsa-miR-4761-3p	CLIP-seq
MIRT2474498	hsa-miR-4761-5p	CLIP-seq
MIRT2474499	hsa-miR-4773	CLIP-seq
MIRT2474500	hsa-miR-486-5p	CLIP-seq
MIRT2474501	hsa-miR-494	CLIP-seq
MIRT2474502	hsa-miR-505	CLIP-seq
MIRT2474503	hsa-miR-513a-3p	CLIP-seq
MIRT2474504	hsa-miR-548ag	CLIP-seq
MIRT2474505	hsa-miR-548ai	CLIP-seq
MIRT2474506	hsa-miR-548m	CLIP-seq
MIRT2474507	hsa-miR-561	CLIP-seq
MIRT2474508	hsa-miR-564	CLIP-seq
MIRT2474509	hsa-miR-567	CLIP-seq
MIRT2474510	hsa-miR-570	CLIP-seq
MIRT2474511	hsa-miR-576-5p	CLIP-seq
MIRT2474512	hsa-miR-582-5p	CLIP-seq
MIRT2171500	hsa-miR-586	CLIP-seq
MIRT2474513	hsa-miR-587	CLIP-seq
MIRT2474514	hsa-miR-600	CLIP-seq
MIRT2474515	hsa-miR-606	CLIP-seq
MIRT2474516	hsa-miR-613	CLIP-seq
MIRT2474517	hsa-miR-623	CLIP-seq
MIRT2474518	hsa-miR-624	CLIP-seq
MIRT2474519	hsa-miR-630	CLIP-seq
MIRT2474520	hsa-miR-649	CLIP-seq
MIRT2474521	hsa-miR-873	CLIP-seq
MIRT1930957	hsa-miR-875-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	21044950
GO:0005929	Component	Cilium	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0019899	Function	Enzyme binding	IEA
GO:0042995	Component	Cell projection	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q8IV38
• Protein name: Ankyrin repeat and MYND domain-containing protein 2
• Protein function: May be involved in the trafficking of signaling proteins to the cilia.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF12796	Ank_2	19 → 110	Ankyrin repeats (3 copies)	Repeat
  PF01753	zf-MYND	320 → 357	MYND finger	Domain

• Sequence:

  MVHIKKGELTQEEKELLEVIGKGTVQEAGTLLSSKNVRVNCLDENGMTPLMHAAYKGKLD
  MCKLLLRHGADVNCHQHEHGYTALMFAALSGNKDITWVMLEAGAETDVVNSVGRTAAQMA
  AFVGQHDCVTIINNFFPRERLDYYTKPQGLDKEPKLPPKLAGPLHKIITTTNLHPVKIVM
  LVNENPLLTEEAALNKCYRVMDLICEKCMKQRDMNEVLAMKMHYISCIFQKCINFLKDGE
  NKLDTLIKSLLKGRASDGFPVYQEKIIRESIRKFPYCEATLLQQLVRSIAPVEIGSDPTA
  FSVLTQAITGQVGFVDVEFCTTCGEKGASKRCSVCKMVIYCDQTCQKTHWFTHKKICKNL
  KDIYEKQQLEAAKEKRQEENHGKLDVNSNCVNEEQPEAEVGISQKDSNPEDSGEGKKESL
  ESEAELEGLQDAPAGPQVSEE

• Sequence length: 441

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
High myopia	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SEVERE MYOPIA	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations