CHPT1 (choline phosphotransferase 1)

Gene
Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
56994
Gene name Gene Name - the full gene name approved by the HGNC.
Choline phosphotransferase 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
CHPT1
Synonyms (NCBI Gene) Gene synonyms aliases
CPT, CPT1
Chromosome Chromosome number
12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12q23.2
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Pathways
Show/Hide all(8)
miRTarBase ID miRNA Experiments Reference
MIRT019907 hsa-miR-375 Microarray 20215506
MIRT024793 hsa-miR-215-5p Microarray 19074876
MIRT026717 hsa-miR-192-5p Microarray 19074876
MIRT031836 hsa-miR-16-5p Microarray 21199864
MIRT891413 hsa-miR-3667-3p CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Pathways
Show/Hide all(17)
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane TAS
GO:0001558 Process Regulation of cell growth NAS 10893425
GO:0004142 Function Diacylglycerol cholinephosphotransferase activity IBA 21873635
GO:0004142 Function Diacylglycerol cholinephosphotransferase activity IDA 10893425
GO:0005515 Function Protein binding IPI 32296183
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Pathways
MIM HGNC e!Ensembl
616747 17852 ENSG00000111666
Protein
Gene miRNA Gene ontology Other IDs Protein Pathways
UniProt ID Q8WUD6
Protein name Cholinephosphotransferase 1 (hCPT1) (EC 2.7.8.2) (AAPT1-like protein) (Diacylglycerol cholinephosphotransferase 1)
Protein function Catalyzes the final step of de novo phosphatidylcholine (PC) synthesis, i.e. the transfer of choline phosphate from CDP-choline to the free hydroxyl of a diacylglycerol (DAG), producing a PC. It thereby plays a central role in the formation and
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01066 CDP-OH_P_transf 61 → 136 CDP-alcohol phosphatidyltransferase Family
Tissue specificity TISSUE SPECIFICITY: Highly expressed in testis, colon, small intestine, heart, prostate and spleen. Also detected in kidney, skeletal muscle, pancreas, leukocytes, ovary and thymus. Weakly expressed in the brain, placenta and lung. Overexpressed in cancer
Sequence 
MAAGAGAGSAPRWLRALSEPLSAAQLRRLEEHRYSAAGVSLLEPPLQLYWTWLLQWIPLW
MAPNSITLLGLAVNVVTTLVLISYCPTATEEAPYWTYLLCALGLFIYQSLDAIDGKQARR
TNSCSPLGELFDHGCDSLSTVFMAVGASIAARLGTYPDWFFFCSFIGMFVFYCAHWQTYV
SGMLRFGKVDVTEIQIALVIVFVLSAFGGATMWDYTIPILEIKLKILPVLGFLGGVIFSC
SNYFHVILHGGVGKNGSTIAGTSVLSPGLHIGLIIILAIMIYKKSATDVFEKHPCLYILM
FGCVFAKVSQKLVVAHMTKSELYLQDTVFLGPGLLFLDQYFNNFIDEYVVLWMAMVISSF
DMVIYFSALCLQISRHLHLNIFKTACHQAPEQVQVLSSKSHQNNMD
Sequence length 406
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Gene ontology Other IDs Protein Pathways
  KEGG   Reactome
  Phosphonate and phosphinate metabolism
Glycerophospholipid metabolism
Ether lipid metabolism
Metabolic pathways
Choline metabolism in cancer 		  Synthesis of PC