OTUD7B (OTU deubiquitinase 7B)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 56957 |
| Gene name | OTU deubiquitinase 7B |
| Gene symbol | OTUD7B |
| Synonyms (NCBI Gene) |
CEZANNEZA20D1
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| Chromosome | 1 |
| Chromosome location | 1q21.2 |
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miRNA
miRNA information provided by mirtarbase database.
609
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
49
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q6GQQ9 | ||||||||||||||||||||
| Protein name | OTU domain-containing protein 7B (EC 3.4.19.12) (Cellular zinc finger anti-NF-kappa-B protein) (Cezanne) (Zinc finger A20 domain-containing protein 1) (Zinc finger protein Cezanne) | ||||||||||||||||||||
| Protein function | Negative regulator of the non-canonical NF-kappa-B pathway that acts by mediating deubiquitination of TRAF3, an inhibitor of the NF-kappa-B pathway, thereby acting as a negative regulator of B-cell responses (PubMed:18178551). In response to non | ||||||||||||||||||||
| PDB | 5LRU , 5LRV , 5LRW | ||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Widely expressed. Abundant in kidney, heart and fetal liver. Expressed differentially among B-cells at distinct developmental stages. Higher expression seen in primary immature B-cells as compared to the mature cells. {ECO:0000269|PubM | ||||||||||||||||||||
| Sequence |
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| Sequence length | 843 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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