Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	56948
Gene name	Short chain dehydrogenase/reductase family 39U member 1
Gene symbol	SDR39U1
Synonyms (NCBI Gene)	C14orf124HCDI
Chromosome	14
Chromosome location	14q12
Summary	This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) superfamily, which includes both classical and extended types. The encoded protein represents an extended type, with similarity to epimerases. Alternatively spliced transcript v

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miRTarBase ID	miRNA	Experiments	Reference
MIRT024076	hsa-miR-1-3p	Proteomics	18668040
MIRT443026	hsa-miR-3174	PAR-CLIP	22100165
MIRT443025	hsa-miR-4524a-3p	PAR-CLIP	22100165
MIRT443024	hsa-miR-3606-5p	PAR-CLIP	22100165
MIRT443023	hsa-miR-921	PAR-CLIP	22100165
MIRT443026	hsa-miR-3174	PAR-CLIP	22100165
MIRT443025	hsa-miR-4524a-3p	PAR-CLIP	22100165
MIRT443024	hsa-miR-3606-5p	PAR-CLIP	22100165
MIRT443023	hsa-miR-921	PAR-CLIP	22100165
MIRT1332060	hsa-miR-18a	CLIP-seq
MIRT1332061	hsa-miR-18b	CLIP-seq
MIRT1332062	hsa-miR-3123	CLIP-seq
MIRT1332063	hsa-miR-3125	CLIP-seq
MIRT1332064	hsa-miR-3153	CLIP-seq
MIRT1332065	hsa-miR-3169	CLIP-seq
MIRT1332066	hsa-miR-3192	CLIP-seq
MIRT1332067	hsa-miR-3916	CLIP-seq
MIRT1332068	hsa-miR-3925-5p	CLIP-seq
MIRT1332069	hsa-miR-4515	CLIP-seq
MIRT1332070	hsa-miR-4646-5p	CLIP-seq
MIRT1332071	hsa-miR-4668-5p	CLIP-seq
MIRT1332072	hsa-miR-4735-3p	CLIP-seq
MIRT1332073	hsa-miR-583	CLIP-seq
MIRT1332074	hsa-miR-600	CLIP-seq
MIRT2322860	hsa-miR-1251	CLIP-seq
MIRT1332063	hsa-miR-3125	CLIP-seq
MIRT2322861	hsa-miR-3151	CLIP-seq
MIRT1332067	hsa-miR-3916	CLIP-seq
MIRT2322862	hsa-miR-4428	CLIP-seq
MIRT2322863	hsa-miR-4434	CLIP-seq
MIRT2322864	hsa-miR-4516	CLIP-seq
MIRT2322865	hsa-miR-4672	CLIP-seq
MIRT2322866	hsa-miR-4795-5p	CLIP-seq
MIRT2322867	hsa-miR-486-3p	CLIP-seq
MIRT2322868	hsa-miR-518d-5p	CLIP-seq
MIRT2322869	hsa-miR-519b-5p	CLIP-seq
MIRT2322870	hsa-miR-519c-5p	CLIP-seq
MIRT2322871	hsa-miR-520c-5p	CLIP-seq
MIRT2322872	hsa-miR-526a	CLIP-seq
MIRT2322873	hsa-miR-877	CLIP-seq
MIRT1332060	hsa-miR-18a	CLIP-seq
MIRT1332061	hsa-miR-18b	CLIP-seq
MIRT1332064	hsa-miR-3153	CLIP-seq
MIRT1332065	hsa-miR-3169	CLIP-seq
MIRT1332069	hsa-miR-4515	CLIP-seq
MIRT1332071	hsa-miR-4668-5p	CLIP-seq
MIRT1332072	hsa-miR-4735-3p	CLIP-seq
MIRT1332073	hsa-miR-583	CLIP-seq
MIRT1332060	hsa-miR-18a	CLIP-seq
MIRT1332061	hsa-miR-18b	CLIP-seq
MIRT1332064	hsa-miR-3153	CLIP-seq
MIRT1332065	hsa-miR-3169	CLIP-seq
MIRT1332066	hsa-miR-3192	CLIP-seq
MIRT1332069	hsa-miR-4515	CLIP-seq
MIRT1332071	hsa-miR-4668-5p	CLIP-seq
MIRT1332072	hsa-miR-4735-3p	CLIP-seq
MIRT1332073	hsa-miR-583	CLIP-seq
MIRT2322860	hsa-miR-1251	CLIP-seq
MIRT2618840	hsa-miR-135a	CLIP-seq
MIRT2618841	hsa-miR-135b	CLIP-seq
MIRT1332060	hsa-miR-18a	CLIP-seq
MIRT1332061	hsa-miR-18b	CLIP-seq
MIRT2618842	hsa-miR-28-5p	CLIP-seq
MIRT1332063	hsa-miR-3125	CLIP-seq
MIRT2618843	hsa-miR-3139	CLIP-seq
MIRT1332064	hsa-miR-3153	CLIP-seq
MIRT1332065	hsa-miR-3169	CLIP-seq
MIRT1332066	hsa-miR-3192	CLIP-seq
MIRT1332067	hsa-miR-3916	CLIP-seq
MIRT2618844	hsa-miR-4511	CLIP-seq
MIRT1332069	hsa-miR-4515	CLIP-seq
MIRT1332071	hsa-miR-4668-5p	CLIP-seq
MIRT1332072	hsa-miR-4735-3p	CLIP-seq
MIRT2322868	hsa-miR-518d-5p	CLIP-seq
MIRT2322869	hsa-miR-519b-5p	CLIP-seq
MIRT2322870	hsa-miR-519c-5p	CLIP-seq
MIRT2322871	hsa-miR-520c-5p	CLIP-seq
MIRT2322872	hsa-miR-526a	CLIP-seq
MIRT2618845	hsa-miR-548b-3p	CLIP-seq
MIRT1332073	hsa-miR-583	CLIP-seq
MIRT2618846	hsa-miR-708	CLIP-seq
MIRT2322873	hsa-miR-877	CLIP-seq
MIRT2322860	hsa-miR-1251	CLIP-seq
MIRT2618840	hsa-miR-135a	CLIP-seq
MIRT2618841	hsa-miR-135b	CLIP-seq
MIRT1332060	hsa-miR-18a	CLIP-seq
MIRT1332061	hsa-miR-18b	CLIP-seq
MIRT1332063	hsa-miR-3125	CLIP-seq
MIRT1332064	hsa-miR-3153	CLIP-seq
MIRT1332065	hsa-miR-3169	CLIP-seq
MIRT1332066	hsa-miR-3192	CLIP-seq
MIRT1332067	hsa-miR-3916	CLIP-seq
MIRT2618844	hsa-miR-4511	CLIP-seq
MIRT1332069	hsa-miR-4515	CLIP-seq
MIRT1332071	hsa-miR-4668-5p	CLIP-seq
MIRT1332072	hsa-miR-4735-3p	CLIP-seq
MIRT2322868	hsa-miR-518d-5p	CLIP-seq
MIRT2322869	hsa-miR-519b-5p	CLIP-seq
MIRT2322870	hsa-miR-519c-5p	CLIP-seq
MIRT2322871	hsa-miR-520c-5p	CLIP-seq
MIRT2322872	hsa-miR-526a	CLIP-seq
MIRT2618845	hsa-miR-548b-3p	CLIP-seq
MIRT1332073	hsa-miR-583	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005634	Component	Nucleus	HDA	21630459
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0016491	Function	Oxidoreductase activity	IEA

MIM	HGNC	e!Ensembl
616162	20275	ENSG00000100445

Q9NRG7

Protein name

Epimerase family protein SDR39U1 (EC 1.1.1.-) (Short-chain dehydrogenase/reductase family 39U member 1)

Protein function

Putative NADP-dependent oxidoreductase.

PDB

4B4O

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01370	Epimerase	3 → 216	NAD dependent epimerase/dehydratase family	Family
PF08338	DUF1731	244 → 291	Domain of unknown function (DUF1731)	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in adrenal gland.

Sequence

MRVLVGGGTGFIGTALTQLLNARGHEVTLVSRKPGPGRITWDELAASGLPSCDAAVNLAG
ENILNPLRRWNETFQKEVIGSRLETTQLLAKAITKAPQPPKAWVLVTGVAYYQPSLTAEY
DEDSPGGDFDFFSNLVTKWEAAARLPGDSTRQVVVRSGVVLGRGGGAMGHMLLPFRLGLG
GPIGSGHQFFPWIHIGDLAGILTHALEANHVHGVLNGVAPSSATNAEFAQTLGAALGRRA
FIPLPSAVVQAVFGRQRAIMLLEGQKVIPQRTLATGYQYSFPELGAALKEIVA

Sequence length

293

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
SMOOTH SURFACE DENTAL CARIES	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

SDR39U1 (short chain dehydrogenase/reductase family 39U member 1)