Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
56924
Gene name Gene Name - the full gene name approved by the HGNC.
P21 (RAC1) activated kinase 6
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
PAK6
Synonyms (NCBI Gene) Gene synonyms aliases
PAK5
Chromosome Chromosome number
15
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
15q15.1
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular pr
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT024945 hsa-miR-215-5p Microarray 19074876
MIRT026453 hsa-miR-192-5p Microarray 19074876
MIRT029237 hsa-miR-26b-5p Microarray 19088304
MIRT608588 hsa-miR-8485 HITS-CLIP 19536157
MIRT612022 hsa-miR-2117 HITS-CLIP 19536157
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000166 Function Nucleotide binding IEA
GO:0001650 Component Fibrillar center IDA
GO:0004672 Function Protein kinase activity IEA
GO:0004674 Function Protein serine/threonine kinase activity IBA
GO:0004674 Function Protein serine/threonine kinase activity IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
608110 16061 ENSG00000137843
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  ErbB signaling pathway
Ras signaling pathway
Axon guidance
Focal adhesion
T cell receptor signaling pathway
Regulation of actin cytoskeleton
Human immunodeficiency virus 1 infection
Renal cell carcinoma
 
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Keratoconus keratoconus N/A N/A ClinVar
Schizophrenia Schizophrenia N/A N/A GWAS
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Breast Neoplasms Stimulate 31987914
Colitis Ulcerative Associate 36272033
Diabetic Nephropathies Associate 37789280
Fibrocartilaginous embolism Associate 36423859
Glioblastoma Associate 39233332
Intervertebral Disc Degeneration Associate 36423859
Leukemia Associate 40650306
Leukemia Myelogenous Chronic BCR ABL Positive Associate 40650306
Lymphatic Metastasis Stimulate 35902562
Melanoma Associate 24204982, 35969127