AGPAT4 (1-acylglycerol-3-phosphate O-acyltransferase 4)

Gene

• Entrez ID: 56895
• Gene name: 1-acylglycerol-3-phosphate O-acyltransferase 4
• Gene symbol: AGPAT4
• Synonyms (NCBI Gene): 1-AGPAT4, LPAAT-delta, LPAAT4, LPLAT4, dJ473J16.2
• Chromosome: 6
• Chromosome location: 6q26
• Summary: This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. [provided by RefSeq, Jul 2008]

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT018200	hsa-miR-335-5p	Microarray	18185580
MIRT036864	hsa-miR-877-3p	CLASH	23622248
MIRT722547	hsa-miR-6849-3p	HITS-CLIP	19536157
MIRT722546	hsa-miR-766-3p	HITS-CLIP	19536157
MIRT722545	hsa-miR-20a-3p	HITS-CLIP	19536157
MIRT722544	hsa-miR-4763-5p	HITS-CLIP	19536157
MIRT722543	hsa-miR-6512-3p	HITS-CLIP	19536157
MIRT722541	hsa-miR-6720-5p	HITS-CLIP	19536157
MIRT722542	hsa-miR-4727-5p	HITS-CLIP	19536157
MIRT722540	hsa-miR-5001-3p	HITS-CLIP	19536157
MIRT722539	hsa-miR-6894-3p	HITS-CLIP	19536157
MIRT722538	hsa-miR-544a	HITS-CLIP	19536157
MIRT722537	hsa-miR-6738-3p	HITS-CLIP	19536157
MIRT717629	hsa-miR-4797-5p	HITS-CLIP	19536157
MIRT717628	hsa-miR-33b-3p	HITS-CLIP	19536157
MIRT717627	hsa-miR-515-3p	HITS-CLIP	19536157
MIRT717626	hsa-miR-519e-3p	HITS-CLIP	19536157
MIRT717625	hsa-miR-759	HITS-CLIP	19536157
MIRT717624	hsa-miR-4778-3p	HITS-CLIP	19536157
MIRT717623	hsa-miR-1909-5p	HITS-CLIP	19536157
MIRT717622	hsa-miR-3682-5p	HITS-CLIP	19536157
MIRT610684	hsa-miR-4691-5p	HITS-CLIP	19536157
MIRT610683	hsa-miR-6792-3p	HITS-CLIP	19536157
MIRT610682	hsa-miR-6749-3p	HITS-CLIP	19536157
MIRT717621	hsa-miR-6875-3p	HITS-CLIP	19536157
MIRT717630	hsa-miR-6750-3p	HITS-CLIP	19536157
MIRT717629	hsa-miR-4797-5p	HITS-CLIP	19536157
MIRT717628	hsa-miR-33b-3p	HITS-CLIP	19536157
MIRT717627	hsa-miR-515-3p	HITS-CLIP	19536157
MIRT717626	hsa-miR-519e-3p	HITS-CLIP	19536157
MIRT717625	hsa-miR-759	HITS-CLIP	19536157
MIRT717624	hsa-miR-4778-3p	HITS-CLIP	19536157
MIRT717623	hsa-miR-1909-5p	HITS-CLIP	19536157
MIRT717622	hsa-miR-3682-5p	HITS-CLIP	19536157
MIRT610684	hsa-miR-4691-5p	HITS-CLIP	19536157
MIRT610683	hsa-miR-6792-3p	HITS-CLIP	19536157
MIRT610682	hsa-miR-6749-3p	HITS-CLIP	19536157
MIRT717621	hsa-miR-6875-3p	HITS-CLIP	19536157
MIRT610686	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610685	hsa-miR-6850-3p	HITS-CLIP	23824327
MIRT610684	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT610683	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT610682	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT610686	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610685	hsa-miR-6850-3p	HITS-CLIP	23824327
MIRT610684	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT610683	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT610682	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT610686	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610685	hsa-miR-6850-3p	HITS-CLIP	23824327
MIRT610684	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT610683	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT610682	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT610686	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610685	hsa-miR-6850-3p	HITS-CLIP	23824327
MIRT610684	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT610683	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT610682	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT610686	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610685	hsa-miR-6850-3p	HITS-CLIP	23824327
MIRT610684	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT610683	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT610682	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT610686	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610685	hsa-miR-6850-3p	HITS-CLIP	23824327
MIRT610684	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT610683	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT610682	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT610686	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610685	hsa-miR-6850-3p	HITS-CLIP	23824327
MIRT610684	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT610683	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT610682	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT722547	hsa-miR-6849-3p	HITS-CLIP	19536157
MIRT722546	hsa-miR-766-3p	HITS-CLIP	19536157
MIRT722545	hsa-miR-20a-3p	HITS-CLIP	19536157
MIRT722544	hsa-miR-4763-5p	HITS-CLIP	19536157
MIRT722543	hsa-miR-6512-3p	HITS-CLIP	19536157
MIRT722541	hsa-miR-6720-5p	HITS-CLIP	19536157
MIRT722542	hsa-miR-4727-5p	HITS-CLIP	19536157
MIRT722540	hsa-miR-5001-3p	HITS-CLIP	19536157
MIRT722539	hsa-miR-6894-3p	HITS-CLIP	19536157
MIRT722538	hsa-miR-544a	HITS-CLIP	19536157
MIRT722537	hsa-miR-6738-3p	HITS-CLIP	19536157
MIRT717629	hsa-miR-4797-5p	HITS-CLIP	19536157
MIRT717628	hsa-miR-33b-3p	HITS-CLIP	19536157
MIRT717627	hsa-miR-515-3p	HITS-CLIP	19536157
MIRT717626	hsa-miR-519e-3p	HITS-CLIP	19536157
MIRT717625	hsa-miR-759	HITS-CLIP	19536157
MIRT717624	hsa-miR-4778-3p	HITS-CLIP	19536157
MIRT717623	hsa-miR-1909-5p	HITS-CLIP	19536157
MIRT717622	hsa-miR-3682-5p	HITS-CLIP	19536157
MIRT610684	hsa-miR-4691-5p	HITS-CLIP	19536157
MIRT610683	hsa-miR-6792-3p	HITS-CLIP	19536157
MIRT610682	hsa-miR-6749-3p	HITS-CLIP	19536157
MIRT717621	hsa-miR-6875-3p	HITS-CLIP	19536157
MIRT717630	hsa-miR-6750-3p	HITS-CLIP	19536157
MIRT717629	hsa-miR-4797-5p	HITS-CLIP	19536157
MIRT717628	hsa-miR-33b-3p	HITS-CLIP	19536157
MIRT717627	hsa-miR-515-3p	HITS-CLIP	19536157
MIRT717626	hsa-miR-519e-3p	HITS-CLIP	19536157
MIRT717625	hsa-miR-759	HITS-CLIP	19536157
MIRT717624	hsa-miR-4778-3p	HITS-CLIP	19536157
MIRT717623	hsa-miR-1909-5p	HITS-CLIP	19536157
MIRT717622	hsa-miR-3682-5p	HITS-CLIP	19536157
MIRT610684	hsa-miR-4691-5p	HITS-CLIP	19536157
MIRT610683	hsa-miR-6792-3p	HITS-CLIP	19536157
MIRT610682	hsa-miR-6749-3p	HITS-CLIP	19536157
MIRT717621	hsa-miR-6875-3p	HITS-CLIP	19536157
MIRT610686	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610685	hsa-miR-6850-3p	HITS-CLIP	23824327
MIRT610684	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT610683	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT610682	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT610686	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610685	hsa-miR-6850-3p	HITS-CLIP	23824327
MIRT610684	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT610683	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT610682	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT610686	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610685	hsa-miR-6850-3p	HITS-CLIP	23824327
MIRT610684	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT610683	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT610682	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT610686	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610685	hsa-miR-6850-3p	HITS-CLIP	23824327
MIRT610684	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT610683	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT610682	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT610686	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610685	hsa-miR-6850-3p	HITS-CLIP	23824327
MIRT610684	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT610683	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT610682	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT610686	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610685	hsa-miR-6850-3p	HITS-CLIP	23824327
MIRT610684	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT610683	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT610682	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT610686	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610685	hsa-miR-6850-3p	HITS-CLIP	23824327
MIRT610684	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT610683	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT610682	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT772579	hsa-miR-1229	CLIP-seq
MIRT772580	hsa-miR-1251	CLIP-seq
MIRT772581	hsa-miR-1265	CLIP-seq
MIRT772582	hsa-miR-134	CLIP-seq
MIRT772583	hsa-miR-1343	CLIP-seq
MIRT772584	hsa-miR-1587	CLIP-seq
MIRT772585	hsa-miR-2116	CLIP-seq
MIRT772586	hsa-miR-2467-3p	CLIP-seq
MIRT772587	hsa-miR-3074-5p	CLIP-seq
MIRT772588	hsa-miR-3118	CLIP-seq
MIRT772589	hsa-miR-3119	CLIP-seq
MIRT772590	hsa-miR-3124-3p	CLIP-seq
MIRT772591	hsa-miR-3164	CLIP-seq
MIRT772592	hsa-miR-3168	CLIP-seq
MIRT772593	hsa-miR-3185	CLIP-seq
MIRT772594	hsa-miR-342-3p	CLIP-seq
MIRT772595	hsa-miR-3658	CLIP-seq
MIRT772596	hsa-miR-3668	CLIP-seq
MIRT772597	hsa-miR-3675-5p	CLIP-seq
MIRT772598	hsa-miR-3690	CLIP-seq
MIRT772599	hsa-miR-377	CLIP-seq
MIRT772600	hsa-miR-3920	CLIP-seq
MIRT772601	hsa-miR-4254	CLIP-seq
MIRT772602	hsa-miR-4278	CLIP-seq
MIRT772603	hsa-miR-4283	CLIP-seq
MIRT772604	hsa-miR-4300	CLIP-seq
MIRT772605	hsa-miR-4417	CLIP-seq
MIRT772606	hsa-miR-4419a	CLIP-seq
MIRT772607	hsa-miR-4489	CLIP-seq
MIRT772608	hsa-miR-4492	CLIP-seq
MIRT772609	hsa-miR-4498	CLIP-seq
MIRT772610	hsa-miR-4501	CLIP-seq
MIRT772611	hsa-miR-4509	CLIP-seq
MIRT772612	hsa-miR-4510	CLIP-seq
MIRT772613	hsa-miR-4649-3p	CLIP-seq
MIRT772614	hsa-miR-4656	CLIP-seq
MIRT772615	hsa-miR-4675	CLIP-seq
MIRT772616	hsa-miR-4677-5p	CLIP-seq
MIRT772617	hsa-miR-4684-5p	CLIP-seq
MIRT772618	hsa-miR-4711-3p	CLIP-seq
MIRT772619	hsa-miR-4719	CLIP-seq
MIRT772620	hsa-miR-4741	CLIP-seq
MIRT772621	hsa-miR-4744	CLIP-seq
MIRT772622	hsa-miR-4761-5p	CLIP-seq
MIRT772623	hsa-miR-4762-3p	CLIP-seq
MIRT772624	hsa-miR-4764-5p	CLIP-seq
MIRT772625	hsa-miR-4799-5p	CLIP-seq
MIRT772626	hsa-miR-498	CLIP-seq
MIRT772627	hsa-miR-511	CLIP-seq
MIRT772628	hsa-miR-518d-5p	CLIP-seq
MIRT772629	hsa-miR-519b-5p	CLIP-seq
MIRT772630	hsa-miR-519c-5p	CLIP-seq
MIRT772631	hsa-miR-520c-5p	CLIP-seq
MIRT772632	hsa-miR-522	CLIP-seq
MIRT772633	hsa-miR-526a	CLIP-seq
MIRT772634	hsa-miR-599	CLIP-seq
MIRT772635	hsa-miR-603	CLIP-seq
MIRT772636	hsa-miR-617	CLIP-seq
MIRT772637	hsa-miR-7	CLIP-seq
MIRT772638	hsa-miR-762	CLIP-seq
MIRT772639	hsa-miR-885-5p	CLIP-seq
MIRT772640	hsa-miR-920	CLIP-seq
MIRT772641	hsa-miR-942	CLIP-seq
MIRT772642	hsa-miR-944	CLIP-seq
MIRT1928016	hsa-miR-1256	CLIP-seq
MIRT1928017	hsa-miR-1296	CLIP-seq
MIRT1928018	hsa-miR-2909	CLIP-seq
MIRT1928019	hsa-miR-3123	CLIP-seq
MIRT1928020	hsa-miR-3125	CLIP-seq
MIRT1928021	hsa-miR-3182	CLIP-seq
MIRT772598	hsa-miR-3690	CLIP-seq
MIRT1928022	hsa-miR-3916	CLIP-seq
MIRT1928023	hsa-miR-3925-3p	CLIP-seq
MIRT1928024	hsa-miR-3928	CLIP-seq
MIRT1928025	hsa-miR-3973	CLIP-seq
MIRT772601	hsa-miR-4254	CLIP-seq
MIRT1928026	hsa-miR-4274	CLIP-seq
MIRT1928027	hsa-miR-4420	CLIP-seq
MIRT1928028	hsa-miR-4773	CLIP-seq
MIRT1928029	hsa-miR-4793-5p	CLIP-seq
MIRT1928030	hsa-miR-518a-5p	CLIP-seq
MIRT1928031	hsa-miR-520g	CLIP-seq
MIRT1928032	hsa-miR-520h	CLIP-seq
MIRT1928033	hsa-miR-527	CLIP-seq
MIRT1928034	hsa-miR-622	CLIP-seq
MIRT2168790	hsa-miR-1	CLIP-seq
MIRT2168791	hsa-miR-1202	CLIP-seq
MIRT2168792	hsa-miR-1207-5p	CLIP-seq
MIRT2168793	hsa-miR-1254	CLIP-seq
MIRT2168794	hsa-miR-15a	CLIP-seq
MIRT2168795	hsa-miR-15b	CLIP-seq
MIRT2168796	hsa-miR-16	CLIP-seq
MIRT2168797	hsa-miR-195	CLIP-seq
MIRT2168798	hsa-miR-206	CLIP-seq
MIRT2168799	hsa-miR-214	CLIP-seq
MIRT2168800	hsa-miR-2278	CLIP-seq
MIRT2168801	hsa-miR-2355-5p	CLIP-seq
MIRT2168802	hsa-miR-3065-3p	CLIP-seq
MIRT2168803	hsa-miR-3116	CLIP-seq
MIRT2168804	hsa-miR-3117-5p	CLIP-seq
MIRT2168805	hsa-miR-3194-5p	CLIP-seq
MIRT772594	hsa-miR-342-3p	CLIP-seq
MIRT2168806	hsa-miR-3612	CLIP-seq
MIRT2168807	hsa-miR-3619-5p	CLIP-seq
MIRT2168808	hsa-miR-3673	CLIP-seq
MIRT2168809	hsa-miR-3934	CLIP-seq
MIRT2168810	hsa-miR-3972	CLIP-seq
MIRT2168811	hsa-miR-424	CLIP-seq
MIRT2168812	hsa-miR-4291	CLIP-seq
MIRT2168813	hsa-miR-4292	CLIP-seq
MIRT2168814	hsa-miR-4308	CLIP-seq
MIRT2168815	hsa-miR-4327	CLIP-seq
MIRT2168816	hsa-miR-4436b-5p	CLIP-seq
MIRT2168817	hsa-miR-4646-5p	CLIP-seq
MIRT2168818	hsa-miR-4659a-5p	CLIP-seq
MIRT2168819	hsa-miR-4659b-5p	CLIP-seq
MIRT772619	hsa-miR-4719	CLIP-seq
MIRT772623	hsa-miR-4762-3p	CLIP-seq
MIRT2168820	hsa-miR-4763-3p	CLIP-seq
MIRT2168821	hsa-miR-4776-3p	CLIP-seq
MIRT2168822	hsa-miR-497	CLIP-seq
MIRT2168823	hsa-miR-512-5p	CLIP-seq
MIRT2168824	hsa-miR-514	CLIP-seq
MIRT2168825	hsa-miR-514b-3p	CLIP-seq
MIRT2168826	hsa-miR-515-5p	CLIP-seq
MIRT2168827	hsa-miR-613	CLIP-seq
MIRT2168828	hsa-miR-650	CLIP-seq
MIRT2168829	hsa-miR-761	CLIP-seq
MIRT2168830	hsa-miR-766	CLIP-seq
MIRT2168831	hsa-miR-767-3p	CLIP-seq
MIRT2168832	hsa-miR-922	CLIP-seq
MIRT2443361	hsa-miR-1245b-3p	CLIP-seq
MIRT2443362	hsa-miR-1324	CLIP-seq
MIRT2443363	hsa-miR-140-3p	CLIP-seq
MIRT2443364	hsa-miR-1912	CLIP-seq
MIRT2443365	hsa-miR-3166	CLIP-seq
MIRT2443366	hsa-miR-3662	CLIP-seq
MIRT772604	hsa-miR-4300	CLIP-seq
MIRT2443367	hsa-miR-4468	CLIP-seq
MIRT2443368	hsa-miR-640	CLIP-seq
MIRT772640	hsa-miR-920	CLIP-seq
MIRT2471331	hsa-miR-1292	CLIP-seq
MIRT2471332	hsa-miR-138	CLIP-seq
MIRT2471333	hsa-miR-147	CLIP-seq
MIRT2471334	hsa-miR-2110	CLIP-seq
MIRT2471335	hsa-miR-2276	CLIP-seq
MIRT772590	hsa-miR-3124-3p	CLIP-seq
MIRT2471336	hsa-miR-3148	CLIP-seq
MIRT2471337	hsa-miR-330-3p	CLIP-seq
MIRT2471338	hsa-miR-3663-5p	CLIP-seq
MIRT2471339	hsa-miR-3667-3p	CLIP-seq
MIRT772599	hsa-miR-377	CLIP-seq
MIRT2471340	hsa-miR-3923	CLIP-seq
MIRT2471341	hsa-miR-4271	CLIP-seq
MIRT737975	hsa-miR-4301	CLIP-seq
MIRT2471342	hsa-miR-4303	CLIP-seq
MIRT2471343	hsa-miR-433	CLIP-seq
MIRT2471344	hsa-miR-4422	CLIP-seq
MIRT2471345	hsa-miR-4471	CLIP-seq
MIRT2471346	hsa-miR-4668-5p	CLIP-seq
MIRT2471347	hsa-miR-4717-3p	CLIP-seq
MIRT2471348	hsa-miR-4725-3p	CLIP-seq
MIRT2471349	hsa-miR-4772-3p	CLIP-seq
MIRT2471350	hsa-miR-520d-5p	CLIP-seq
MIRT2471351	hsa-miR-524-5p	CLIP-seq
MIRT2471352	hsa-miR-548aa	CLIP-seq
MIRT772635	hsa-miR-603	CLIP-seq
MIRT2443368	hsa-miR-640	CLIP-seq
MIRT2471331	hsa-miR-1292	CLIP-seq
MIRT2471333	hsa-miR-147	CLIP-seq
MIRT2471334	hsa-miR-2110	CLIP-seq
MIRT2471336	hsa-miR-3148	CLIP-seq
MIRT2471337	hsa-miR-330-3p	CLIP-seq
MIRT772599	hsa-miR-377	CLIP-seq
MIRT2471340	hsa-miR-3923	CLIP-seq
MIRT2471341	hsa-miR-4271	CLIP-seq
MIRT737975	hsa-miR-4301	CLIP-seq
MIRT2471342	hsa-miR-4303	CLIP-seq
MIRT2471344	hsa-miR-4422	CLIP-seq
MIRT2471345	hsa-miR-4471	CLIP-seq
MIRT2471346	hsa-miR-4668-5p	CLIP-seq
MIRT2471347	hsa-miR-4717-3p	CLIP-seq
MIRT2471348	hsa-miR-4725-3p	CLIP-seq
MIRT2471350	hsa-miR-520d-5p	CLIP-seq
MIRT2471351	hsa-miR-524-5p	CLIP-seq
MIRT2471352	hsa-miR-548aa	CLIP-seq
MIRT772635	hsa-miR-603	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003841	Function	1-acylglycerol-3-phosphate O-acyltransferase activity	IBA
GO:0003841	Function	1-acylglycerol-3-phosphate O-acyltransferase activity	IEA
GO:0003841	Function	1-acylglycerol-3-phosphate O-acyltransferase activity	ISS
GO:0003841	Function	1-acylglycerol-3-phosphate O-acyltransferase activity	NAS	15367102
GO:0003841	Function	1-acylglycerol-3-phosphate O-acyltransferase activity	TAS
GO:0005515	Function	Protein binding	IPI	25416956, 32296183
GO:0005741	Component	Mitochondrial outer membrane	IBA
GO:0005741	Component	Mitochondrial outer membrane	IEA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005783	Component	Endoplasmic reticulum	ISS
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	TAS
GO:0006629	Process	Lipid metabolic process	IEA
GO:0006644	Process	Phospholipid metabolic process	IEA
GO:0006654	Process	Phosphatidic acid biosynthetic process	TAS
GO:0008654	Process	Phospholipid biosynthetic process	IEA
GO:0008654	Process	Phospholipid biosynthetic process	NAS	15367102
GO:0012505	Component	Endomembrane system	IBA
GO:0016020	Component	Membrane	IEA
GO:0016024	Process	CDP-diacylglycerol biosynthetic process	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0016746	Function	Acyltransferase activity	IEA
GO:0042171	Function	Lysophosphatidic acid acyltransferase activity	IEA

Other IDs

• MIM: 614795
• HGNC: 20885
• e!Ensembl: ENSG00000026652

Protein

• UniProt ID: Q9NRZ5
• Protein name: 1-acyl-sn-glycerol-3-phosphate acyltransferase delta (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 4) (1-AGP acyltransferase 4) (1-AGPAT 4) (Lysophosphatidic acid acyltransferase delta) (LPAAT-delta)
• Protein function: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity). Exhibits high
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01553	Acyltransferase	70 → 233	Acyltransferase	Family
  PF16076	Acyltransf_C	242 → 314	Acyltransferase C-terminus	Family

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed with highest levels in skeletal muscle, followed by heart, liver, prostate and thymus. {ECO:0000269|PubMed:21173190}.
• Sequence:

  MDLAGLLKSQFLCHLVFCYVFIASGLIINTIQLFTLLLWPINKQLFRKINCRLSYCISSQ
  LVMLLEWWSGTECTIFTDPRAYLKYGKENAIVVLNHKFEIDFLCGWSLSERFGLLGGSKV
  LAKKELAYVPIIGWMWYFTEMVFCSRKWEQDRKTVATSLQHLRDYPEKYFFLIHCEGTRF
  TEKKHEISMQVARAKGLPRLKHHLLPRTKGFAITVRSLRNVVSAVYDCTLNFRNNENPTL
  LGVLNGKKYHADLYVRRIPLEDIPEDDDECSAWLHKLYQEKDAFQEEYYRTGTFPETPMV
  PPRRPWTLVNWLFWASLVLYPFFQFLVSMIRSGSSLTLASFILVFFVASVGVRWMIGVTE
  IDKGSAYGNSDSKQKLND

• Sequence length: 378

Pathways

KEGG:

Glycerolipid metabolism
Glycerophospholipid metabolism
Metabolic pathways
Phospholipase D signaling pathway

Reactome:

Synthesis of PA

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
CARDIOVASCULAR DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLOR VISION DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CORONARY ARTERY DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYOCARDIAL INFARCTION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS, HAND	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
UPPER AERODIGESTIVE TRACT NEOPLASM	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Relationship Type	References	Evidence Score
Breast Neoplasms	Associate	29965997	★☆☆☆☆ Found in Text Mining only
Developmental Disabilities	Associate	31694657	★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Associate	31694657	★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Associate	35844514	★☆☆☆☆ Found in Text Mining only