AGPAT3 (1-acylglycerol-3-phosphate O-acyltransferase 3)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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56894 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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1-acylglycerol-3-phosphate O-acyltransferase 3 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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AGPAT3 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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1-AGPAT 3, LPAAT-GAMMA1, LPAAT3, LPLAT3 |
Chromosome
Chromosome number
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21 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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21q22.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is an acyltransferase that converts lysophosphatidic acid into phosphatidic acid, which is the second step in the de novo phospholipid biosynthetic pathway. The encoded protein may be an integral membrane protein. Two tran |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||
UniProt ID | Q9NRZ7 | |||||||||||||||
Protein name | 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 3) (1-AGP acyltransferase 3) (1-AGPAT 3) (Lysophosphatidic acid acyltransferase gamma) (LPAAT-gamma) | |||||||||||||||
Protein function | Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (PubMed:21173190). Acts on LPA | |||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Widely expressed with highest levels in testis, pancreas and kidney, followed by spleen, lung, adipose tissue and liver. {ECO:0000269|PubMed:21173190}. | |||||||||||||||
Sequence |
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Sequence length | 376 | |||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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