Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
56894
Gene name Gene Name - the full gene name approved by the HGNC.
1-acylglycerol-3-phosphate O-acyltransferase 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
AGPAT3
Synonyms (NCBI Gene) Gene synonyms aliases
1-AGPAT 3, LPAAT-GAMMA1, LPAAT3, LPLAT3
Chromosome Chromosome number
21
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
21q22.3
Summary Summary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene is an acyltransferase that converts lysophosphatidic acid into phosphatidic acid, which is the second step in the de novo phospholipid biosynthetic pathway. The encoded protein may be an integral membrane protein. Two tran
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT016086 hsa-miR-744-5p Sequencing 20371350
MIRT017029 hsa-miR-335-5p Microarray 18185580
MIRT029038 hsa-miR-26b-5p Sequencing 20371350
MIRT030467 hsa-miR-24-3p Microarray 19748357
MIRT030467 hsa-miR-24-3p Sequencing 20371350
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane TAS
GO:0003841 Function 1-acylglycerol-3-phosphate O-acyltransferase activity IBA 21873635
GO:0003841 Function 1-acylglycerol-3-phosphate O-acyltransferase activity IDA 21173190
GO:0003841 Function 1-acylglycerol-3-phosphate O-acyltransferase activity NAS 15367102
GO:0003841 Function 1-acylglycerol-3-phosphate O-acyltransferase activity TAS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
614794 326 ENSG00000160216
Protein
UniProt ID Q9NRZ7
Protein name 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 3) (1-AGP acyltransferase 3) (1-AGPAT 3) (Lysophosphatidic acid acyltransferase gamma) (LPAAT-gamma)
Protein function Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (PubMed:21173190). Acts on LPA
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01553 Acyltransferase 74 233 Acyltransferase Family
PF16076 Acyltransf_C 242 314 Acyltransferase C-terminus Family
Tissue specificity TISSUE SPECIFICITY: Widely expressed with highest levels in testis, pancreas and kidney, followed by spleen, lung, adipose tissue and liver. {ECO:0000269|PubMed:21173190}.
Sequence
Sequence length 376
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  Glycerolipid metabolism
Glycerophospholipid metabolism
Metabolic pathways
Phospholipase D signaling pathway
  Synthesis of PA
COPI-independent Golgi-to-ER retrograde traffic