GPR137 (G protein-coupled receptor 137)

Gene

• Entrez ID: 56834
• Gene name: G protein-coupled receptor 137
• Gene symbol: GPR137
• Synonyms (NCBI Gene): C11orf4, GPR137A, TM7SF1L1
• Chromosome: 11
• Chromosome location: 11q13.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT756143	hsa-miR-134-3p	Luciferase reporter assay, Western blotting, qRT-PCR	38021163
MIRT1030434	hsa-let-7a	CLIP-seq
MIRT1030435	hsa-let-7b	CLIP-seq
MIRT1030436	hsa-let-7c	CLIP-seq
MIRT1030437	hsa-let-7d	CLIP-seq
MIRT1030438	hsa-let-7e	CLIP-seq
MIRT1030439	hsa-let-7f	CLIP-seq
MIRT1030440	hsa-let-7g	CLIP-seq
MIRT1030441	hsa-let-7i	CLIP-seq
MIRT1030442	hsa-miR-149	CLIP-seq
MIRT1030443	hsa-miR-3190	CLIP-seq
MIRT1030444	hsa-miR-3911	CLIP-seq
MIRT1030445	hsa-miR-4458	CLIP-seq
MIRT1030446	hsa-miR-4500	CLIP-seq
MIRT1030447	hsa-miR-4768-3p	CLIP-seq
MIRT1030448	hsa-miR-671-5p	CLIP-seq
MIRT1030449	hsa-miR-98	CLIP-seq
MIRT2005741	hsa-miR-4736	CLIP-seq
MIRT2005741	hsa-miR-4736	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005764	Component	Lysosome	IEA
GO:0005765	Component	Lysosomal membrane	IBA
GO:0005765	Component	Lysosomal membrane	IDA	31036939
GO:0005765	Component	Lysosomal membrane	IEA
GO:0006914	Process	Autophagy	IEA
GO:0010506	Process	Regulation of autophagy	IBA
GO:0016020	Component	Membrane	IEA
GO:0045671	Process	Negative regulation of osteoclast differentiation	IBA
GO:0045779	Process	Negative regulation of bone resorption	IBA
GO:1904263	Process	Positive regulation of TORC1 signaling	IBA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q96N19
• Protein name: Integral membrane protein GPR137 (Transmembrane 7 superfamily member 1-like 1 protein)
• Protein function: Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes (PubMed:31036939). May play a role in autophagy (PubMed:31036939). ; May activate Wnt/beta-catenin signaling
• Sequence:

  MESNLSGLVPAAGLVPALPPAVTLGLTAAYTTLYALLFFSVYAQLWLVLLYGHKRLSYQT
  VFLALCLLWAALRTTLFSFYFRDTPRANRLGPLPFWLLYCCPVCLQFFTLTLMNLYFAQV
  VFKAKVKRRPEMSRGLLAVRGAFVGASLLFLLVNVLCAVLSHRRRAQPWALLLVRVLVSD
  SLFVICALSLAACLCLVARRAPSTSIYLEAKGTSVCQAAAMGGAMVLLYASRACYNLTAL
  ALAPQSRLDTFDYDWYNVSDQADLVNDLGNKGYLVFGLILFVWELLPTTLLVGFFRVHRP
  PQDLSTSHILNGQVFASRSYFFDRAGHCEDEGCSWEHSRGESTRCQDQAATTTVSTPPHR
  RDPPPSPTEYPGPSPPHPRPLCQVCLPLLAQDPGGRGYPLLWPAPCCSCHSELVPSP

• Sequence length: 417