PSG11 (pregnancy specific beta-1-glycoprotein 11)

Gene

• Entrez ID: 5680
• Gene name: Pregnancy specific beta-1-glycoprotein 11
• Gene symbol: PSG11
• Synonyms (NCBI Gene): PSBG-11, PSBG-13, PSG13, PSG14
• Chromosome: 19
• Chromosome location: 19q13.31
• Summary: The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy. PSGs comprise a subgroup of the carcinoembryonic antigen (CEA) family, which belongs to the immunog

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT444921	hsa-miR-1825	PAR-CLIP	22100165
MIRT444920	hsa-miR-199a-5p	PAR-CLIP	22100165
MIRT444919	hsa-miR-199b-5p	PAR-CLIP	22100165
MIRT444918	hsa-miR-4635	PAR-CLIP	22100165
MIRT444917	hsa-miR-4670-3p	PAR-CLIP	22100165
MIRT444916	hsa-miR-6723-5p	PAR-CLIP	22100165
MIRT444915	hsa-miR-4540	PAR-CLIP	22100165
MIRT444914	hsa-miR-3616-5p	PAR-CLIP	22100165
MIRT444913	hsa-miR-573	PAR-CLIP	22100165
MIRT444921	hsa-miR-1825	PAR-CLIP	22100165
MIRT444920	hsa-miR-199a-5p	PAR-CLIP	22100165
MIRT444919	hsa-miR-199b-5p	PAR-CLIP	22100165
MIRT444918	hsa-miR-4635	PAR-CLIP	22100165
MIRT444917	hsa-miR-4670-3p	PAR-CLIP	22100165
MIRT444916	hsa-miR-6723-5p	PAR-CLIP	22100165
MIRT444915	hsa-miR-4540	PAR-CLIP	22100165
MIRT444914	hsa-miR-3616-5p	PAR-CLIP	22100165
MIRT444913	hsa-miR-573	PAR-CLIP	22100165
MIRT444921	hsa-miR-1825	PAR-CLIP	22100165
MIRT444920	hsa-miR-199a-5p	PAR-CLIP	22100165
MIRT444919	hsa-miR-199b-5p	PAR-CLIP	22100165
MIRT444918	hsa-miR-4635	PAR-CLIP	22100165
MIRT444917	hsa-miR-4670-3p	PAR-CLIP	22100165
MIRT444916	hsa-miR-6723-5p	PAR-CLIP	22100165
MIRT444915	hsa-miR-4540	PAR-CLIP	22100165
MIRT444914	hsa-miR-3616-5p	PAR-CLIP	22100165
MIRT444913	hsa-miR-573	PAR-CLIP	22100165
MIRT444921	hsa-miR-1825	PAR-CLIP	22100165
MIRT444920	hsa-miR-199a-5p	PAR-CLIP	22100165
MIRT444919	hsa-miR-199b-5p	PAR-CLIP	22100165
MIRT444918	hsa-miR-4635	PAR-CLIP	22100165
MIRT444917	hsa-miR-4670-3p	PAR-CLIP	22100165
MIRT444916	hsa-miR-6723-5p	PAR-CLIP	22100165
MIRT444915	hsa-miR-4540	PAR-CLIP	22100165
MIRT444914	hsa-miR-3616-5p	PAR-CLIP	22100165
MIRT444913	hsa-miR-573	PAR-CLIP	22100165
MIRT1269662	hsa-miR-203	CLIP-seq
MIRT1269663	hsa-miR-4653-3p	CLIP-seq
MIRT1269664	hsa-miR-4659a-3p	CLIP-seq
MIRT1269665	hsa-miR-4659b-3p	CLIP-seq
MIRT1269666	hsa-miR-4694-3p	CLIP-seq
MIRT1269667	hsa-miR-1224-5p	CLIP-seq
MIRT1269668	hsa-miR-1304	CLIP-seq
MIRT1269669	hsa-miR-3915	CLIP-seq
MIRT1269670	hsa-miR-3928	CLIP-seq
MIRT1269671	hsa-miR-4689	CLIP-seq
MIRT2305598	hsa-miR-335	CLIP-seq
MIRT2305599	hsa-miR-361-5p	CLIP-seq
MIRT2305600	hsa-miR-4272	CLIP-seq
MIRT2305601	hsa-miR-630	CLIP-seq
MIRT2305602	hsa-miR-643	CLIP-seq
MIRT2305603	hsa-miR-873	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005576	Component	Extracellular region	IEA
GO:0007157	Process	Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IBA
GO:0007565	Process	Female pregnancy	TAS	1690992, 7794280
GO:0009986	Component	Cell surface	IBA

Other IDs

• MIM: 176401
• HGNC: 9516
• e!Ensembl: ENSG00000243130

Protein

• UniProt ID: Q9UQ72
• Protein name: Pregnancy-specific beta-1-glycoprotein 11 (PS-beta-G-11) (PSBG-11) (Pregnancy-specific glycoprotein 11) (Pregnancy-specific beta-1-glycoprotein 13) (PS-beta-G-13) (PSBG-13) (Pregnancy-specific glycoprotein 13)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07686	V-set	38 → 139	Immunoglobulin V-set domain	Domain
  PF13927	Ig_3	148 → 221		Domain
  PF13895	Ig_2	241 → 320	Immunoglobulin domain	Domain

• Sequence:

  MGPLSAPPCTEHIKWKGLLLTALLLNFWNLPTTAQVMIEAQPPKVSEGKDVLLLVHNLPQ
  NLTGYIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETVYSNASLLIQNVTREDAGSY
  TLHIIKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAMETVILTCNPETPDASYLW
  WMNGQSLPMTHRMQLSETNRTLFLFGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPD
  LPRIFPSVTSYYSGENLDLSCFANSNPPAQYSWTINGKFQLSGQKLFIPQITPKHNGLYA
  CSARNSATGEESSTSLTIRVIAPPGLGTFAFNNPT

• Sequence length: 335

Pathways

Reactome:

Cell surface interactions at the vascular wall