PSG6 (pregnancy specific beta-1-glycoprotein 6)

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID 5675
Gene name Pregnancy specific beta-1-glycoprotein 6
Gene symbol PSG6
Synonyms (NCBI Gene)
PSBG-10PSBG-12PSBG-6PSG10PSGGB
Chromosome 19
Chromosome location 19q13.31
Summary This gene is a member of the pregnancy-specific glycoprotein (PSG) gene family. The PSG genes are a subgroup of the carcinoembryonic antigen (CEA) family of immunoglobulin-like genes, and are found in a gene cluster at 19q13.1-q13.2 telomeric to another c
miRNA miRNA information provided by mirtarbase database.
8
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all (8)
miRTarBase ID miRNA Experiments Reference
MIRT023643 hsa-miR-1-3p Microarray 18668037
MIRT1269735 hsa-miR-4314 CLIP-seq
MIRT1269736 hsa-miR-4667-5p CLIP-seq
MIRT1269737 hsa-miR-4700-5p CLIP-seq
MIRT1269738 hsa-miR-637 CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
4
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all (4)
GO ID Ontology Definition Evidence Reference
GO:0005576 Component Extracellular region IEA
GO:0005576 Component Extracellular region NAS 2271648
GO:0007565 Process Female pregnancy NAS 2271648
GO:0007565 Process Female pregnancy TAS 1690992
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
176395 9523 ENSG00000170848
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q00889
Protein name Pregnancy-specific beta-1-glycoprotein 6 (PS-beta-G-6) (PSBG-6) (Pregnancy-specific glycoprotein 6) (Pregnancy-specific beta-1-glycoprotein 10) (PS-beta-G-10) (PSBG-10) (Pregnancy-specific glycoprotein 10) (Pregnancy-specific beta-1-glycoprotein 12) (PS-b
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07686 V-set 38 → 140 Immunoglobulin V-set domain Domain
PF13895 Ig_2 240 → 327 Immunoglobulin domain Domain
PF13895 Ig_2 333 → 412 Immunoglobulin domain Domain
Sequence
Sequence length 435
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
  Reactome
    Cell surface interactions at the vascular wall
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Show/Hide Unknown Diseases (1)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
AUTISM SPECTRUM DISORDER — CTD
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Show/Hide Text Mining Associations (3)
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Gestational Trophoblastic Disease Associate 2377620
★★★★★
★☆☆☆☆
Found in Text Mining only
Hydatidiform Mole Associate 2377620
★★★★★
★☆☆☆☆
Found in Text Mining only
Stomach Neoplasms Associate 32034058
★★★★★
★☆☆☆☆
Found in Text Mining only