Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	5672
Gene name	Pregnancy specific beta-1-glycoprotein 4
Gene symbol	PSG4
Synonyms (NCBI Gene)	PSBG-4PSBG-9PSG9
Chromosome	19
Chromosome location	19q13.31
Summary	The protein encoded by this gene is a pregnancy-specific glycoprotein (PSG), one of several encoded by a cluster of similar genes on chromosome 19. This gene is a member of the carcinoembryonic antigen (CEA) gene family and may play a role in regulation o

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miRTarBase ID	miRNA	Experiments	Reference
MIRT437515	hsa-miR-19b-3p	Immunoprecipitaion	22382630
MIRT724778	hsa-miR-7109-3p	HITS-CLIP	19536157
MIRT724777	hsa-miR-6819-3p	HITS-CLIP	19536157
MIRT724776	hsa-miR-6877-3p	HITS-CLIP	19536157
MIRT724775	hsa-miR-6892-3p	HITS-CLIP	19536157
MIRT724774	hsa-miR-2276-5p	HITS-CLIP	19536157
MIRT724773	hsa-miR-3183	HITS-CLIP	19536157
MIRT724772	hsa-miR-4723-3p	HITS-CLIP	19536157
MIRT724770	hsa-miR-6769b-3p	HITS-CLIP	19536157
MIRT724771	hsa-miR-1237-3p	HITS-CLIP	19536157
MIRT724769	hsa-miR-1248	HITS-CLIP	19536157
MIRT724768	hsa-miR-6817-3p	HITS-CLIP	19536157
MIRT724767	hsa-miR-146a-3p	HITS-CLIP	19536157
MIRT724766	hsa-miR-301a-5p	HITS-CLIP	19536157
MIRT724765	hsa-miR-301b-5p	HITS-CLIP	19536157
MIRT724764	hsa-miR-3921	HITS-CLIP	19536157
MIRT724763	hsa-miR-4653-5p	HITS-CLIP	19536157
MIRT724762	hsa-miR-3655	HITS-CLIP	19536157
MIRT724761	hsa-miR-4786-3p	HITS-CLIP	19536157
MIRT724760	hsa-miR-642a-5p	HITS-CLIP	19536157
MIRT724759	hsa-miR-6868-3p	HITS-CLIP	19536157
MIRT724758	hsa-miR-7843-3p	HITS-CLIP	19536157
MIRT724757	hsa-miR-4433b-5p	HITS-CLIP	19536157
MIRT724756	hsa-miR-578	HITS-CLIP	19536157
MIRT724755	hsa-miR-4646-3p	HITS-CLIP	19536157
MIRT724778	hsa-miR-7109-3p	HITS-CLIP	19536157
MIRT724777	hsa-miR-6819-3p	HITS-CLIP	19536157
MIRT724776	hsa-miR-6877-3p	HITS-CLIP	19536157
MIRT724775	hsa-miR-6892-3p	HITS-CLIP	19536157
MIRT724774	hsa-miR-2276-5p	HITS-CLIP	19536157
MIRT724773	hsa-miR-3183	HITS-CLIP	19536157
MIRT724772	hsa-miR-4723-3p	HITS-CLIP	19536157
MIRT724770	hsa-miR-6769b-3p	HITS-CLIP	19536157
MIRT724771	hsa-miR-1237-3p	HITS-CLIP	19536157
MIRT724769	hsa-miR-1248	HITS-CLIP	19536157
MIRT724768	hsa-miR-6817-3p	HITS-CLIP	19536157
MIRT724767	hsa-miR-146a-3p	HITS-CLIP	19536157
MIRT724766	hsa-miR-301a-5p	HITS-CLIP	19536157
MIRT724765	hsa-miR-301b-5p	HITS-CLIP	19536157
MIRT724764	hsa-miR-3921	HITS-CLIP	19536157
MIRT724763	hsa-miR-4653-5p	HITS-CLIP	19536157
MIRT724762	hsa-miR-3655	HITS-CLIP	19536157
MIRT724761	hsa-miR-4786-3p	HITS-CLIP	19536157
MIRT724760	hsa-miR-642a-5p	HITS-CLIP	19536157
MIRT724759	hsa-miR-6868-3p	HITS-CLIP	19536157
MIRT724758	hsa-miR-7843-3p	HITS-CLIP	19536157
MIRT724757	hsa-miR-4433b-5p	HITS-CLIP	19536157
MIRT724756	hsa-miR-578	HITS-CLIP	19536157
MIRT724755	hsa-miR-4646-3p	HITS-CLIP	19536157
MIRT1269709	hsa-miR-1827	CLIP-seq
MIRT1269710	hsa-miR-583	CLIP-seq
MIRT1269711	hsa-miR-940	CLIP-seq
MIRT1269712	hsa-miR-125a-5p	CLIP-seq
MIRT1269713	hsa-miR-125b	CLIP-seq
MIRT1269714	hsa-miR-1273f	CLIP-seq
MIRT1269715	hsa-miR-143	CLIP-seq
MIRT1269716	hsa-miR-24	CLIP-seq
MIRT1269717	hsa-miR-331-3p	CLIP-seq
MIRT1269718	hsa-miR-3679-3p	CLIP-seq
MIRT1269719	hsa-miR-4284	CLIP-seq
MIRT1269720	hsa-miR-4303	CLIP-seq
MIRT1269721	hsa-miR-4319	CLIP-seq
MIRT1269722	hsa-miR-4324	CLIP-seq
MIRT1269723	hsa-miR-4481	CLIP-seq
MIRT1269724	hsa-miR-4682	CLIP-seq
MIRT1269725	hsa-miR-4708-5p	CLIP-seq
MIRT1269726	hsa-miR-4710	CLIP-seq
MIRT1269727	hsa-miR-4745-5p	CLIP-seq
MIRT1269728	hsa-miR-4758-5p	CLIP-seq
MIRT1269729	hsa-miR-4770	CLIP-seq
MIRT1269730	hsa-miR-4792	CLIP-seq
MIRT2079264	hsa-miR-1267	CLIP-seq
MIRT2079265	hsa-miR-3117-5p	CLIP-seq
MIRT2079266	hsa-miR-3200-5p	CLIP-seq
MIRT2079267	hsa-miR-3660	CLIP-seq
MIRT2079268	hsa-miR-3664-5p	CLIP-seq
MIRT2079269	hsa-miR-4526	CLIP-seq
MIRT2079264	hsa-miR-1267	CLIP-seq
MIRT2602696	hsa-miR-128	CLIP-seq
MIRT2602697	hsa-miR-217	CLIP-seq
MIRT2079265	hsa-miR-3117-5p	CLIP-seq
MIRT2602698	hsa-miR-3148	CLIP-seq
MIRT2602699	hsa-miR-3607-5p	CLIP-seq
MIRT2602700	hsa-miR-3611	CLIP-seq
MIRT2079268	hsa-miR-3664-5p	CLIP-seq
MIRT2602701	hsa-miR-3978	CLIP-seq
MIRT2602702	hsa-miR-4302	CLIP-seq
MIRT2602703	hsa-miR-4446-5p	CLIP-seq
MIRT2602704	hsa-miR-4480	CLIP-seq
MIRT2602705	hsa-miR-4666-5p	CLIP-seq
MIRT2602706	hsa-miR-4717-3p	CLIP-seq
MIRT2602707	hsa-miR-4722-3p	CLIP-seq
MIRT2602708	hsa-miR-548a-3p	CLIP-seq
MIRT2602709	hsa-miR-548ae	CLIP-seq
MIRT2602710	hsa-miR-548aj	CLIP-seq
MIRT2602711	hsa-miR-548am	CLIP-seq
MIRT2602712	hsa-miR-548e	CLIP-seq
MIRT2602713	hsa-miR-548f	CLIP-seq
MIRT2602714	hsa-miR-548g	CLIP-seq
MIRT2602715	hsa-miR-548x	CLIP-seq
MIRT2602716	hsa-miR-576-5p	CLIP-seq
MIRT2602717	hsa-miR-624	CLIP-seq
MIRT2602718	hsa-miR-9	CLIP-seq
MIRT2602719	hsa-miR-3913-3p	CLIP-seq
MIRT2602720	hsa-miR-489	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005576	Component	Extracellular region	IEA
GO:0007565	Process	Female pregnancy	TAS	1690992, 7794280

MIM	HGNC	e!Ensembl
176393	9521	ENSG00000243137

Q00888

Protein name

Pregnancy-specific beta-1-glycoprotein 4 (PS-beta-G-4) (PSBG-4) (Pregnancy-specific glycoprotein 4) (Pregnancy-specific beta-1-glycoprotein 9) (PS-beta-G-9) (PSBG-9) (Pregnancy-specific glycoprotein 9)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07686	V-set	38 → 143	Immunoglobulin V-set domain	Domain
PF13927	Ig_3	148 → 221		Domain
PF13895	Ig_2	238 → 328	Immunoglobulin domain	Domain
PF13895	Ig_2	334 → 413	Immunoglobulin domain	Domain

Sequence

MGPLSAPPCTQRITWKGVLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQ
NLAGYIWYKGQMTYLYHYITSYVVDGQRIIYGPAYSGRERVYSNASLLIQNVTQEDAGSY
TLHIIKRRDGTGGVTGHFTFTLHLETPKPSISSSNLNPREAMEAVILTCDPATPAASYQW
WMNGQSLPMTHRLQLSKTNRTLFIFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLS
KPYITINNLNPRENKDVLTFTCEPKSKNYTYIWWLNGQSLPVSPRVKRPIENRILILPNV
TRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPSIYPSFTYYRSGENLYLSCFAESNP
RAQYSWTINGKFQLSGQKLSIPQITTKHSGLYACSVRNSATGKESSKSITVKVSDWILP

Sequence length

419

Interactions

View interactions

	Reactome
			Cell surface interactions at the vascular wall

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
AUTISM SPECTRUM DISORDER	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (4)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Adenocarcinoma of Lung	Associate	33824285	★★★★★ ★☆☆☆☆ Found in Text Mining only
Exocrine Pancreatic Insufficiency	Associate	33857242	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Associate	33824285	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Associate	33824285	★★★★★ ★☆☆☆☆ Found in Text Mining only

PSG4 (pregnancy specific beta-1-glycoprotein 4)