Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	5669
Gene name	Pregnancy specific beta-1-glycoprotein 1
Gene symbol	PSG1
Synonyms (NCBI Gene)	B1G1CD66fDHFRP2FL-NCA-1/2PBG1PS-beta-C/DPS-beta-G-1PSBG-1PSBG1PSG95PSGGAPSGIIASP1
Chromosome	19
Chromosome location	19q13.2
Summary	The human placenta is a multihormonal endocrine organ that produces hormones, enzymes, and other molecules that support fetal survival and development. Pregnancy-specific beta-1-glycoprotein (PSBG, PSG) is a major product of the syncytiotrophoblast, reach

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miRTarBase ID	miRNA	Experiments
MIRT1269672	hsa-miR-1827	CLIP-seq
MIRT1269673	hsa-miR-24	CLIP-seq
MIRT1269674	hsa-miR-4284	CLIP-seq
MIRT1269675	hsa-miR-4303	CLIP-seq
MIRT1269676	hsa-miR-4481	CLIP-seq
MIRT1269677	hsa-miR-4682	CLIP-seq
MIRT1269678	hsa-miR-4710	CLIP-seq
MIRT1269679	hsa-miR-4745-5p	CLIP-seq
MIRT1269680	hsa-miR-4758-5p	CLIP-seq
MIRT1269681	hsa-miR-4792	CLIP-seq
MIRT1269682	hsa-miR-583	CLIP-seq
MIRT1269683	hsa-miR-940	CLIP-seq
MIRT2079261	hsa-miR-3660	CLIP-seq
MIRT2079262	hsa-miR-4526	CLIP-seq
MIRT2305604	hsa-miR-1298	CLIP-seq
MIRT2602669	hsa-miR-1267	CLIP-seq
MIRT2602670	hsa-miR-128	CLIP-seq
MIRT2602671	hsa-miR-217	CLIP-seq
MIRT2602672	hsa-miR-3117-5p	CLIP-seq
MIRT2602673	hsa-miR-3148	CLIP-seq
MIRT2602674	hsa-miR-3153	CLIP-seq
MIRT2602675	hsa-miR-3607-5p	CLIP-seq
MIRT2602676	hsa-miR-3611	CLIP-seq
MIRT2602677	hsa-miR-3664-5p	CLIP-seq
MIRT2602678	hsa-miR-3913-3p	CLIP-seq
MIRT2602679	hsa-miR-4302	CLIP-seq
MIRT2602680	hsa-miR-4330	CLIP-seq
MIRT2602681	hsa-miR-4436b-5p	CLIP-seq
MIRT2602682	hsa-miR-4666-5p	CLIP-seq
MIRT2602683	hsa-miR-4668-5p	CLIP-seq
MIRT2602684	hsa-miR-4722-3p	CLIP-seq
MIRT2602685	hsa-miR-489	CLIP-seq
MIRT2602686	hsa-miR-548a-3p	CLIP-seq
MIRT2602687	hsa-miR-548ae	CLIP-seq
MIRT2602688	hsa-miR-548aj	CLIP-seq
MIRT2602689	hsa-miR-548am	CLIP-seq
MIRT2602690	hsa-miR-548e	CLIP-seq
MIRT2602691	hsa-miR-548f	CLIP-seq
MIRT2602692	hsa-miR-548g	CLIP-seq
MIRT2602693	hsa-miR-548x	CLIP-seq
MIRT2602694	hsa-miR-576-5p	CLIP-seq
MIRT2602695	hsa-miR-635	CLIP-seq

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Transcription factor	Regulation	Reference
MYBL2	Unknown	14613485

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 25548275
GO:0005576	Component	Extracellular region	IEA
GO:0005576	Component	Extracellular region	TAS
GO:0007565	Process	Female pregnancy	TAS	1572651

MIM	HGNC	e!Ensembl
176390	9514	ENSG00000231924

P11464

Protein name

Pregnancy-specific beta-1-glycoprotein 1 (PS-beta-G-1) (PSBG-1) (Pregnancy-specific glycoprotein 1) (CD66 antigen-like family member F) (Fetal liver non-specific cross-reactive antigen 1/2) (FL-NCA-1/2) (PSG95) (Pregnancy-specific beta-1 glycoprotein C/D)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07686	V-set	38 → 144	Immunoglobulin V-set domain	Domain
PF13927	Ig_3	148 → 221		Domain
PF13895	Ig_2	241 → 328	Immunoglobulin domain	Domain
PF13895	Ig_2	334 → 413	Immunoglobulin domain	Domain

Sequence

MGTLSAPPCTQRIKWKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQ
NLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSY
TLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLW
WMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLP
KPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSV
TRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNP
PAQYSWTINEKFQLPGQKLFIRHITTKHSGLYVCSVRNSATGKESSKSMTVEVSDWTVP

Sequence length

419

Interactions

View interactions

	Reactome
			Cell surface interactions at the vascular wall

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
AUTISM SPECTRUM DISORDER	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (4)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
COVID 19	Associate	37475853	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hydatidiform Mole	Associate	2377620	★★★★★ ★☆☆☆☆ Found in Text Mining only
Kidney Failure Chronic	Associate	30212930	★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Associate	36309385	★★★★★ ★☆☆☆☆ Found in Text Mining only

PSG1 (pregnancy specific beta-1-glycoprotein 1)