Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	56252
Gene name Gene Name - the full gene name approved by the HGNC.	YLP motif containing 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	YLPM1
Synonyms (NCBI Gene) Gene synonyms aliases	C14orf170, PPP1R169, ZAP113, ZAP3
Chromosome Chromosome number	14
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	14q24.3

Show/Hide all(135)

miRTarBase ID	miRNA	Experiments	Reference
MIRT052085	hsa-let-7b-5p	CLASH	23622248
MIRT046757	hsa-miR-222-3p	CLASH	23622248
MIRT1499080	hsa-miR-1245b-5p	CLIP-seq
MIRT1499081	hsa-miR-1272	CLIP-seq
MIRT1499082	hsa-miR-146a	CLIP-seq
MIRT1499083	hsa-miR-146b-5p	CLIP-seq
MIRT1499084	hsa-miR-2110	CLIP-seq
MIRT1499085	hsa-miR-216a	CLIP-seq
MIRT1499086	hsa-miR-2681	CLIP-seq
MIRT1499087	hsa-miR-3125	CLIP-seq
MIRT1499088	hsa-miR-3142	CLIP-seq
MIRT1499089	hsa-miR-3144-5p	CLIP-seq
MIRT1499090	hsa-miR-3150a-3p	CLIP-seq
MIRT1499091	hsa-miR-3191	CLIP-seq
MIRT1499092	hsa-miR-330-3p	CLIP-seq
MIRT1499093	hsa-miR-3613-3p	CLIP-seq
MIRT1499094	hsa-miR-3651	CLIP-seq
MIRT1499095	hsa-miR-3682-3p	CLIP-seq
MIRT1499096	hsa-miR-3908	CLIP-seq
MIRT1499097	hsa-miR-3916	CLIP-seq
MIRT1499098	hsa-miR-3976	CLIP-seq
MIRT1499099	hsa-miR-4282	CLIP-seq
MIRT1499100	hsa-miR-4434	CLIP-seq
MIRT1499101	hsa-miR-4504	CLIP-seq
MIRT1499102	hsa-miR-4516	CLIP-seq
MIRT1499103	hsa-miR-4531	CLIP-seq
MIRT1499104	hsa-miR-4641	CLIP-seq
MIRT1499105	hsa-miR-4652-5p	CLIP-seq
MIRT1499106	hsa-miR-4666-5p	CLIP-seq
MIRT1499107	hsa-miR-4677-3p	CLIP-seq
MIRT1499108	hsa-miR-4679	CLIP-seq
MIRT1499109	hsa-miR-4691-3p	CLIP-seq
MIRT1499110	hsa-miR-4718	CLIP-seq
MIRT1499111	hsa-miR-542-3p	CLIP-seq
MIRT1499112	hsa-miR-548m	CLIP-seq
MIRT1499113	hsa-miR-561	CLIP-seq
MIRT1499114	hsa-miR-635	CLIP-seq
MIRT1499115	hsa-miR-759	CLIP-seq
MIRT1499116	hsa-miR-877	CLIP-seq
MIRT1499080	hsa-miR-1245b-5p	CLIP-seq
MIRT2150275	hsa-miR-1470	CLIP-seq
MIRT2150276	hsa-miR-204	CLIP-seq
MIRT2150277	hsa-miR-211	CLIP-seq
MIRT2150278	hsa-miR-2114	CLIP-seq
MIRT2150279	hsa-miR-214	CLIP-seq
MIRT1499087	hsa-miR-3125	CLIP-seq
MIRT1499088	hsa-miR-3142	CLIP-seq
MIRT2150280	hsa-miR-3163	CLIP-seq
MIRT1499092	hsa-miR-330-3p	CLIP-seq
MIRT2150281	hsa-miR-338-3p	CLIP-seq
MIRT2150282	hsa-miR-34c-3p	CLIP-seq
MIRT2150283	hsa-miR-3619-5p	CLIP-seq
MIRT2150284	hsa-miR-3673	CLIP-seq
MIRT1499097	hsa-miR-3916	CLIP-seq
MIRT1499098	hsa-miR-3976	CLIP-seq
MIRT2150285	hsa-miR-4291	CLIP-seq
MIRT2150286	hsa-miR-4469	CLIP-seq
MIRT2150287	hsa-miR-4530	CLIP-seq
MIRT2150288	hsa-miR-4652-3p	CLIP-seq
MIRT2150289	hsa-miR-4667-3p	CLIP-seq
MIRT2150290	hsa-miR-4691-5p	CLIP-seq
MIRT2150291	hsa-miR-483-3p	CLIP-seq
MIRT2150292	hsa-miR-642b	CLIP-seq
MIRT2150293	hsa-miR-761	CLIP-seq
MIRT2150294	hsa-miR-765	CLIP-seq
MIRT2150295	hsa-miR-766	CLIP-seq
MIRT1499116	hsa-miR-877	CLIP-seq
MIRT2150296	hsa-miR-922	CLIP-seq
MIRT2370576	hsa-miR-101	CLIP-seq
MIRT1499080	hsa-miR-1245b-5p	CLIP-seq
MIRT2370577	hsa-miR-144	CLIP-seq
MIRT2150275	hsa-miR-1470	CLIP-seq
MIRT2370578	hsa-miR-224	CLIP-seq
MIRT2370579	hsa-miR-298	CLIP-seq
MIRT2370580	hsa-miR-3120-5p	CLIP-seq
MIRT2370581	hsa-miR-3127-5p	CLIP-seq
MIRT1499088	hsa-miR-3142	CLIP-seq
MIRT1499092	hsa-miR-330-3p	CLIP-seq
MIRT2150282	hsa-miR-34c-3p	CLIP-seq
MIRT2370582	hsa-miR-3614-5p	CLIP-seq
MIRT2370583	hsa-miR-3618	CLIP-seq
MIRT2370584	hsa-miR-382	CLIP-seq
MIRT2370585	hsa-miR-3942-3p	CLIP-seq
MIRT2370586	hsa-miR-4270	CLIP-seq
MIRT2370587	hsa-miR-4277	CLIP-seq
MIRT2370588	hsa-miR-4441	CLIP-seq
MIRT2150286	hsa-miR-4469	CLIP-seq
MIRT2150289	hsa-miR-4667-3p	CLIP-seq
MIRT2370589	hsa-miR-4720-3p	CLIP-seq
MIRT2370590	hsa-miR-4804-3p	CLIP-seq
MIRT2150291	hsa-miR-483-3p	CLIP-seq
MIRT2370591	hsa-miR-548c-3p	CLIP-seq
MIRT2370592	hsa-miR-548k	CLIP-seq
MIRT2370593	hsa-miR-548n	CLIP-seq
MIRT2370594	hsa-miR-548t	CLIP-seq
MIRT2370595	hsa-miR-577	CLIP-seq
MIRT2150292	hsa-miR-642b	CLIP-seq
MIRT2370596	hsa-miR-934	CLIP-seq
MIRT2370597	hsa-miR-935	CLIP-seq
MIRT1499080	hsa-miR-1245b-5p	CLIP-seq
MIRT1499088	hsa-miR-3142	CLIP-seq
MIRT1499092	hsa-miR-330-3p	CLIP-seq
MIRT2150292	hsa-miR-642b	CLIP-seq
MIRT2463688	hsa-miR-31	CLIP-seq
MIRT2463689	hsa-miR-3660	CLIP-seq
MIRT2463690	hsa-miR-4438	CLIP-seq
MIRT2463691	hsa-miR-4511	CLIP-seq
MIRT2463692	hsa-miR-4526	CLIP-seq
MIRT2463693	hsa-miR-570	CLIP-seq
MIRT1499080	hsa-miR-1245b-5p	CLIP-seq
MIRT2664273	hsa-miR-1267	CLIP-seq
MIRT2150279	hsa-miR-214	CLIP-seq
MIRT1499087	hsa-miR-3125	CLIP-seq
MIRT1499088	hsa-miR-3142	CLIP-seq
MIRT1499092	hsa-miR-330-3p	CLIP-seq
MIRT2150281	hsa-miR-338-3p	CLIP-seq
MIRT2150283	hsa-miR-3619-5p	CLIP-seq
MIRT2150284	hsa-miR-3673	CLIP-seq
MIRT1499097	hsa-miR-3916	CLIP-seq
MIRT2150285	hsa-miR-4291	CLIP-seq
MIRT2150287	hsa-miR-4530	CLIP-seq
MIRT2150290	hsa-miR-4691-5p	CLIP-seq
MIRT2150292	hsa-miR-642b	CLIP-seq
MIRT2150293	hsa-miR-761	CLIP-seq
MIRT2150294	hsa-miR-765	CLIP-seq
MIRT2150295	hsa-miR-766	CLIP-seq
MIRT1499116	hsa-miR-877	CLIP-seq
MIRT2150296	hsa-miR-922	CLIP-seq
MIRT1499080	hsa-miR-1245b-5p	CLIP-seq
MIRT1499087	hsa-miR-3125	CLIP-seq
MIRT1499088	hsa-miR-3142	CLIP-seq
MIRT1499092	hsa-miR-330-3p	CLIP-seq
MIRT1499097	hsa-miR-3916	CLIP-seq
MIRT2150292	hsa-miR-642b	CLIP-seq
MIRT1499116	hsa-miR-877	CLIP-seq

Show/Hide all(9)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003723	Function	RNA binding	HDA	22681889
GO:0005515	Function	Protein binding	IPI	21078624, 22321011, 28330616
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005634	Component	Nucleus	IDA	17890166
GO:0005654	Component	Nucleoplasm	IDA
GO:0005829	Component	Cytosol	IDA
GO:0008150	Process	Biological_process	ND
GO:0016607	Component	Nuclear speck	IDA
GO:0032204	Process	Regulation of telomere maintenance	IBA	21873635

MIM	HGNC	e!Ensembl
619766	17798	ENSG00000119596

Protein

UniProt ID

P49750

Protein name

YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113)

Protein function

Plays a role in the reduction of telomerase activity during differentiation of embryonic stem cells by binding to the core promoter of TERT and controlling its down-regulation.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF13671	AAA_33	1836 → 1996		Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in neuronal, neuroblastoma and embryonic kidney cell lines (at protein level). {ECO:0000269|PubMed:17890166}.

Sequence

MYPNWGRYGGSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQ
LQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQ
QQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSS
QPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHS
KSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQ
HLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEV
PPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQ
QIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEK
QWKTWQGHMKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPP
SLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAG
PPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSS
QVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGL
GESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRP
KGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPRQSGPQWKGP
KPAFGQQHQQQPKSQAEPLSGNKEPLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQSNE
NLSDSQQEPPKSEVSEGPVEPSNWDQNVQSMETQIDKAQAVTQPVPLANKPVPAQSTFPS
KTGGMEGGTAVATSSLTADNDFKPVGIGLPHSENNQDKGLPRPDNRDNRLEGNRGNSSSY
RGPGQSRMEDTRDKGLVNRGRGQAISRGPGLVKQEDFRDKMMGRREDSREKMNRGEGSRD
RGLVRPGSSREKVPGGLQGSQDRGAAGSRERGPPRRAGSQERGPLRRAGSRERIPPRRAG
SRERGPPRGPGSRERGLGRSDFGRDRGPFRPEPGDGGEKMYPYHRDEPPRAPWNHGEERG
HEEFPLDGRNAPMERERLDDWDRERYWRECERDYQDDTLELYNREDRFSAPPSRSHDGDR
RGPWWDDWERDQDMDEDYNREMERDMDRDVDRISRPMDMYDRSLDNEWDRDYGRPLDEQE
SQFRERDIPSLPPLPPLPPLPPLDRYRDDRWREERNREHGYDRDFRDRGELRIREYPERG
DTWREKRDYVPDRMDWERERLSDRWYPSDVDRHSPMAEHMPSSHHSSEMMGSDASLDSDQ
GLGGVMVLSQRQHEIILKAAQELKMLREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTS
SRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPP
VIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPP
GPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGERITLRPDPLPERSTFETEHA
GQRDRYDRERDREPYFDRQSNVIADHRDFKRDRETHRDRDRDRGVIDYDRDRFDRERRPR
DDRAQSYRDKKDHSSSRRGGFDRPSYDRKSDRPVYEGPSMFGGERRTYPEERMPLPAPSL
SHQPPPAPRVEKKPESKNVDDILKPPGRESRPERIVVIMRGLPGSGKTHVAKLIRDKEVE
FGGPAPRVLSLDDYFITEVEKEEKDPDSGKKVKKKVMEYEYEAEMEETYRTSMFKTFKKT
LDDGFFPFIILDAINDRVRHFDQFWSAAKTKGFEVYLAEMSADNQTCGKRNIHGRKLKEI
NKMADHWETAPRHMMRLDIRSLLQDAAIEEVEMEDFDANIEEQKEEKKDAEEEESELGYI
PKSKWEMDTSEAKLDKLDGLRTGTKRKRDWEAIASRMEDYLQLPDDYDTRASEPGKKRVR
WADLEEKKDADRKRAIGFVVGQTDWEKITDESGHLAEKALNRTKYI

Sequence length

2146

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Leukemia	Leukemia, Myelocytic, Acute	rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297	27903959

Show/Hide Unknown Diseases (3)

Disease term	Disease name	References	Source
Unknown
Mental depression	Major Depressive Disorder	29662059, 29942085	ClinVar
Neuroticism	Neuroticism		GWAS
Gastroesophageal Reflux Disease	Gastroesophageal Reflux Disease		GWAS

YLPM1 (YLP motif containing 1)