Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	56142
Gene name Gene Name - the full gene name approved by the HGNC.	Protocadherin alpha 6
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	PCDHA6
Synonyms (NCBI Gene) Gene synonyms aliases	CNR2, CNRN2, CNRS2, CRNR2, PCDH-ALPHA6
Chromosome Chromosome number	5
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	5q31.3
Summary Summary of gene provided in NCBI Entrez Gene.	This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha ge

Show/Hide all(149)

miRTarBase ID	miRNA	Experiments	Reference
MIRT028979	hsa-miR-26b-5p	Microarray	19088304
MIRT053676	hsa-miR-181a-5p	Microarray	22942087
MIRT053711	hsa-miR-221-3p	Microarray	22942087
MIRT637159	hsa-miR-6890-3p	HITS-CLIP	19536157
MIRT637158	hsa-miR-6823-5p	HITS-CLIP	19536157
MIRT637157	hsa-miR-7113-5p	HITS-CLIP	19536157
MIRT637156	hsa-miR-4685-5p	HITS-CLIP	19536157
MIRT637155	hsa-miR-6837-5p	HITS-CLIP	19536157
MIRT717270	hsa-miR-6741-3p	HITS-CLIP	19536157
MIRT637151	hsa-miR-1304-3p	HITS-CLIP	19536157
MIRT717269	hsa-miR-1307-3p	HITS-CLIP	19536157
MIRT717268	hsa-miR-4638-5p	HITS-CLIP	19536157
MIRT637148	hsa-miR-4772-3p	HITS-CLIP	19536157
MIRT637147	hsa-miR-6778-3p	HITS-CLIP	19536157
MIRT637145	hsa-miR-6791-3p	HITS-CLIP	19536157
MIRT637146	hsa-miR-6829-3p	HITS-CLIP	19536157
MIRT717267	hsa-miR-4284	HITS-CLIP	19536157
MIRT637143	hsa-miR-5001-3p	HITS-CLIP	19536157
MIRT637142	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT662895	hsa-miR-34b-3p	HITS-CLIP	23824327
MIRT662894	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT662893	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT662892	hsa-miR-940	HITS-CLIP	23824327
MIRT662891	hsa-miR-3929	HITS-CLIP	23824327
MIRT662890	hsa-miR-4419b	HITS-CLIP	23824327
MIRT662889	hsa-miR-4478	HITS-CLIP	23824327
MIRT662887	hsa-miR-5002-5p	HITS-CLIP	23824327
MIRT662888	hsa-miR-3614-5p	HITS-CLIP	23824327
MIRT662886	hsa-miR-6500-3p	HITS-CLIP	23824327
MIRT662885	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT662884	hsa-miR-665	HITS-CLIP	23824327
MIRT662883	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT662882	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT662881	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT662880	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT662879	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT662878	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT662877	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT662876	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT662875	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT662874	hsa-miR-3122	HITS-CLIP	23824327
MIRT662873	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT662872	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT662871	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT637160	hsa-miR-5571-5p	HITS-CLIP	23824327
MIRT637159	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT637158	hsa-miR-6823-5p	HITS-CLIP	23824327
MIRT637157	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT637156	hsa-miR-4685-5p	HITS-CLIP	23824327
MIRT637155	hsa-miR-6837-5p	HITS-CLIP	23824327
MIRT637154	hsa-miR-6748-3p	HITS-CLIP	23824327
MIRT637153	hsa-miR-4421	HITS-CLIP	23824327
MIRT637152	hsa-miR-5699-3p	HITS-CLIP	23824327
MIRT637151	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT637149	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT637150	hsa-miR-1976	HITS-CLIP	23824327
MIRT637148	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT637147	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT637145	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT637146	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT637144	hsa-miR-4279	HITS-CLIP	23824327
MIRT637143	hsa-miR-5001-3p	HITS-CLIP	23824327
MIRT637142	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT637141	hsa-miR-498	HITS-CLIP	23824327
MIRT449598	hsa-miR-548l	PAR-CLIP	22100165
MIRT449596	hsa-miR-3681-5p	PAR-CLIP	22100165
MIRT449597	hsa-miR-6849-5p	PAR-CLIP	22100165
MIRT449595	hsa-miR-4635	PAR-CLIP	22100165
MIRT449594	hsa-miR-3145-3p	PAR-CLIP	22100165
MIRT449593	hsa-miR-3201	PAR-CLIP	22100165
MIRT449592	hsa-miR-4791	PAR-CLIP	22100165
MIRT449591	hsa-miR-431-5p	PAR-CLIP	22100165
MIRT449590	hsa-miR-376b-5p	PAR-CLIP	22100165
MIRT449589	hsa-miR-376c-5p	PAR-CLIP	22100165
MIRT449588	hsa-miR-488-3p	PAR-CLIP	22100165
MIRT449587	hsa-miR-511-5p	PAR-CLIP	22100165
MIRT637159	hsa-miR-6890-3p	HITS-CLIP	19536157
MIRT637158	hsa-miR-6823-5p	HITS-CLIP	19536157
MIRT637157	hsa-miR-7113-5p	HITS-CLIP	19536157
MIRT637156	hsa-miR-4685-5p	HITS-CLIP	19536157
MIRT637155	hsa-miR-6837-5p	HITS-CLIP	19536157
MIRT717270	hsa-miR-6741-3p	HITS-CLIP	19536157
MIRT637151	hsa-miR-1304-3p	HITS-CLIP	19536157
MIRT717269	hsa-miR-1307-3p	HITS-CLIP	19536157
MIRT717268	hsa-miR-4638-5p	HITS-CLIP	19536157
MIRT637148	hsa-miR-4772-3p	HITS-CLIP	19536157
MIRT637147	hsa-miR-6778-3p	HITS-CLIP	19536157
MIRT637145	hsa-miR-6791-3p	HITS-CLIP	19536157
MIRT637146	hsa-miR-6829-3p	HITS-CLIP	19536157
MIRT717267	hsa-miR-4284	HITS-CLIP	19536157
MIRT637143	hsa-miR-5001-3p	HITS-CLIP	19536157
MIRT637142	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT662895	hsa-miR-34b-3p	HITS-CLIP	23824327
MIRT662894	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT662893	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT662892	hsa-miR-940	HITS-CLIP	23824327
MIRT662891	hsa-miR-3929	HITS-CLIP	23824327
MIRT662890	hsa-miR-4419b	HITS-CLIP	23824327
MIRT662889	hsa-miR-4478	HITS-CLIP	23824327
MIRT662887	hsa-miR-5002-5p	HITS-CLIP	23824327
MIRT662888	hsa-miR-3614-5p	HITS-CLIP	23824327
MIRT662886	hsa-miR-6500-3p	HITS-CLIP	23824327
MIRT662885	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT662884	hsa-miR-665	HITS-CLIP	23824327
MIRT662883	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT662882	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT662881	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT662880	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT662879	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT662878	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT662877	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT662876	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT662875	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT662874	hsa-miR-3122	HITS-CLIP	23824327
MIRT662873	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT662872	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT662871	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT637160	hsa-miR-5571-5p	HITS-CLIP	23824327
MIRT637159	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT637158	hsa-miR-6823-5p	HITS-CLIP	23824327
MIRT637157	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT637156	hsa-miR-4685-5p	HITS-CLIP	23824327
MIRT637155	hsa-miR-6837-5p	HITS-CLIP	23824327
MIRT637154	hsa-miR-6748-3p	HITS-CLIP	23824327
MIRT637153	hsa-miR-4421	HITS-CLIP	23824327
MIRT637152	hsa-miR-5699-3p	HITS-CLIP	23824327
MIRT637151	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT637149	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT637150	hsa-miR-1976	HITS-CLIP	23824327
MIRT637148	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT637147	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT637145	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT637146	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT637144	hsa-miR-4279	HITS-CLIP	23824327
MIRT637143	hsa-miR-5001-3p	HITS-CLIP	23824327
MIRT637142	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT637141	hsa-miR-498	HITS-CLIP	23824327
MIRT449598	hsa-miR-548l	PAR-CLIP	22100165
MIRT449596	hsa-miR-3681-5p	PAR-CLIP	22100165
MIRT449597	hsa-miR-6849-5p	PAR-CLIP	22100165
MIRT449595	hsa-miR-4635	PAR-CLIP	22100165
MIRT449594	hsa-miR-3145-3p	PAR-CLIP	22100165
MIRT449593	hsa-miR-3201	PAR-CLIP	22100165
MIRT449592	hsa-miR-4791	PAR-CLIP	22100165
MIRT449591	hsa-miR-431-5p	PAR-CLIP	22100165
MIRT449590	hsa-miR-376b-5p	PAR-CLIP	22100165
MIRT449589	hsa-miR-376c-5p	PAR-CLIP	22100165
MIRT449588	hsa-miR-488-3p	PAR-CLIP	22100165
MIRT449587	hsa-miR-511-5p	PAR-CLIP	22100165

Show/Hide all(6)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005509	Function	Calcium ion binding	IEA
GO:0005576	Component	Extracellular region	IEA
GO:0005887	Component	Integral component of plasma membrane	IBA	21873635
GO:0007155	Process	Cell adhesion	IBA	21873635
GO:0007156	Process	Homophilic cell adhesion via plasma membrane adhesion molecules	IEA
GO:0007399	Process	Nervous system development	TAS	10380929

MIM	HGNC	e!Ensembl
606312	8672	ENSG00000081842

Protein

UniProt ID

Q9UN73

Protein name

Protocadherin alpha-6 (PCDH-alpha-6)

Protein function

Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF08266	Cadherin_2	30 → 112	Cadherin-like	Domain
PF00028	Cadherin	138 → 233	Cadherin domain	Domain
PF00028	Cadherin	247 → 341	Cadherin domain	Domain
PF00028	Cadherin	355 → 446	Cadherin domain	Domain
PF00028	Cadherin	460 → 556	Cadherin domain	Domain
PF00028	Cadherin	577 → 670	Cadherin domain	Domain
PF15974	Cadherin_tail	800 → 933	Cadherin C-terminal cytoplasmic tail, catenin-binding region	Family

Sequence

MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV
PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD
VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL
DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP
TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG
EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR
EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA
YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR
DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA
GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD
SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT
ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA
LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP
IMMGKAENQDLNEDHDAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP
TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR
QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ

Sequence length

950

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Prostate cancer	Malignant neoplasm of prostate	rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582	24185611

Show/Hide Unknown Diseases (4)

Disease term	Disease name	References	Source
Unknown
Mental depression	Major Depressive Disorder	27479909, 29942085	ClinVar
Mental Depression	Mental Depression		GWAS
Schizophrenia	Schizophrenia		GWAS
Insomnia	Insomnia		GWAS

Show/Hide Text Mining Associations (1)

Disease Name	Relationship Type	References
Associations from Text Mining
Myopia	Associate	36036911

PCDHA6 (protocadherin alpha 6)