AJAP1 (adherens junctions associated protein 1)

Gene

• Entrez ID: 55966
• Gene name: Adherens junctions associated protein 1
• Gene symbol: AJAP1
• Synonyms (NCBI Gene): MOT8, SHREW-1, SHREW1
• Chromosome: 1
• Chromosome location: 1p36.32

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT722005	hsa-miR-6889-3p	HITS-CLIP	19536157
MIRT709670	hsa-miR-4641	HITS-CLIP	19536157
MIRT709669	hsa-miR-6778-3p	HITS-CLIP	19536157
MIRT709668	hsa-miR-6791-3p	HITS-CLIP	19536157
MIRT709667	hsa-miR-6829-3p	HITS-CLIP	19536157
MIRT709666	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT709665	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT709670	hsa-miR-4641	HITS-CLIP	19536157
MIRT709669	hsa-miR-6778-3p	HITS-CLIP	19536157
MIRT709668	hsa-miR-6791-3p	HITS-CLIP	19536157
MIRT709667	hsa-miR-6829-3p	HITS-CLIP	19536157
MIRT709666	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT709665	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT713443	hsa-miR-2278	HITS-CLIP	19536157
MIRT713442	hsa-miR-204-3p	HITS-CLIP	19536157
MIRT713441	hsa-miR-4646-5p	HITS-CLIP	19536157
MIRT713440	hsa-miR-3192-5p	HITS-CLIP	19536157
MIRT713439	hsa-miR-619-5p	HITS-CLIP	19536157
MIRT713438	hsa-miR-6506-5p	HITS-CLIP	19536157
MIRT713437	hsa-miR-3184-5p	HITS-CLIP	19536157
MIRT713436	hsa-miR-423-5p	HITS-CLIP	19536157
MIRT713435	hsa-miR-1914-3p	HITS-CLIP	19536157
MIRT713434	hsa-miR-5194	HITS-CLIP	19536157
MIRT713433	hsa-miR-6738-5p	HITS-CLIP	19536157
MIRT713432	hsa-miR-6878-5p	HITS-CLIP	19536157
MIRT713431	hsa-miR-6731-5p	HITS-CLIP	19536157
MIRT713430	hsa-miR-8085	HITS-CLIP	19536157
MIRT713429	hsa-miR-4710	HITS-CLIP	19536157
MIRT713428	hsa-miR-4314	HITS-CLIP	19536157
MIRT713427	hsa-miR-6734-5p	HITS-CLIP	19536157
MIRT713426	hsa-miR-30c-1-3p	HITS-CLIP	19536157
MIRT713425	hsa-miR-30c-2-3p	HITS-CLIP	19536157
MIRT713424	hsa-miR-6788-5p	HITS-CLIP	19536157
MIRT709670	hsa-miR-4641	HITS-CLIP	19536157
MIRT709669	hsa-miR-6778-3p	HITS-CLIP	19536157
MIRT709668	hsa-miR-6791-3p	HITS-CLIP	19536157
MIRT709667	hsa-miR-6829-3p	HITS-CLIP	19536157
MIRT709666	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT709665	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT709670	hsa-miR-4641	HITS-CLIP	19536157
MIRT709669	hsa-miR-6778-3p	HITS-CLIP	19536157
MIRT709668	hsa-miR-6791-3p	HITS-CLIP	19536157
MIRT709667	hsa-miR-6829-3p	HITS-CLIP	19536157
MIRT709666	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT709665	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT709664	hsa-miR-7108-3p	HITS-CLIP	19536157
MIRT709663	hsa-miR-4313	HITS-CLIP	19536157
MIRT615492	hsa-miR-656-3p	HITS-CLIP	19536157
MIRT615491	hsa-miR-1279	HITS-CLIP	19536157
MIRT618717	hsa-miR-5007-3p	HITS-CLIP	19536157
MIRT615490	hsa-miR-335-3p	HITS-CLIP	19536157
MIRT515853	hsa-miR-4789-3p	HITS-CLIP	21572407
MIRT515852	hsa-miR-3163	HITS-CLIP	21572407
MIRT515851	hsa-miR-410-3p	HITS-CLIP	21572407
MIRT515843	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT515850	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT707213	hsa-miR-4731-3p	HITS-CLIP	21572407
MIRT707212	hsa-miR-4801	HITS-CLIP	21572407
MIRT515849	hsa-miR-8485	HITS-CLIP	21572407
MIRT515848	hsa-miR-329-3p	HITS-CLIP	21572407
MIRT515847	hsa-miR-362-3p	HITS-CLIP	21572407
MIRT515846	hsa-miR-603	HITS-CLIP	21572407
MIRT515845	hsa-miR-3941	HITS-CLIP	21572407
MIRT515853	hsa-miR-4789-3p	HITS-CLIP	21572407
MIRT515843	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT515850	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT515858	hsa-miR-548aa	HITS-CLIP	23313552
MIRT515857	hsa-miR-548ap-3p	HITS-CLIP	23313552
MIRT515856	hsa-miR-548t-3p	HITS-CLIP	23313552
MIRT515855	hsa-miR-548at-3p	HITS-CLIP	23313552
MIRT515854	hsa-miR-548ay-3p	HITS-CLIP	23313552
MIRT515853	hsa-miR-4789-3p	HITS-CLIP	23313552
MIRT705817	hsa-miR-6813-3p	HITS-CLIP	23313552
MIRT515852	hsa-miR-3163	HITS-CLIP	23313552
MIRT515851	hsa-miR-410-3p	HITS-CLIP	23313552
MIRT515843	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT515850	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT515858	hsa-miR-548aa	HITS-CLIP	23313552
MIRT515857	hsa-miR-548ap-3p	HITS-CLIP	23313552
MIRT515856	hsa-miR-548t-3p	HITS-CLIP	23313552
MIRT684153	hsa-miR-548as-3p	HITS-CLIP	23313552
MIRT515855	hsa-miR-548at-3p	HITS-CLIP	23313552
MIRT515854	hsa-miR-548ay-3p	HITS-CLIP	23313552
MIRT515853	hsa-miR-4789-3p	HITS-CLIP	23313552
MIRT515852	hsa-miR-3163	HITS-CLIP	23313552
MIRT515851	hsa-miR-410-3p	HITS-CLIP	23313552
MIRT615492	hsa-miR-656-3p	HITS-CLIP	23824327
MIRT615491	hsa-miR-1279	HITS-CLIP	23824327
MIRT618717	hsa-miR-5007-3p	HITS-CLIP	23824327
MIRT615490	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT615492	hsa-miR-656-3p	HITS-CLIP	23824327
MIRT615491	hsa-miR-1279	HITS-CLIP	23824327
MIRT615490	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT515850	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT515858	hsa-miR-548aa	PAR-CLIP	23446348
MIRT515857	hsa-miR-548ap-3p	PAR-CLIP	23446348
MIRT515856	hsa-miR-548t-3p	PAR-CLIP	23446348
MIRT515855	hsa-miR-548at-3p	PAR-CLIP	23446348
MIRT515854	hsa-miR-548ay-3p	PAR-CLIP	23446348
MIRT515853	hsa-miR-4789-3p	PAR-CLIP	23446348
MIRT515852	hsa-miR-3163	PAR-CLIP	23446348
MIRT515851	hsa-miR-410-3p	PAR-CLIP	23446348
MIRT515850	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT515849	hsa-miR-8485	PAR-CLIP	23446348
MIRT515848	hsa-miR-329-3p	PAR-CLIP	23446348
MIRT515847	hsa-miR-362-3p	PAR-CLIP	23446348
MIRT515846	hsa-miR-603	PAR-CLIP	23446348
MIRT515845	hsa-miR-3941	PAR-CLIP	23446348
MIRT515844	hsa-miR-4789-5p	PAR-CLIP	23446348
MIRT515843	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT497359	hsa-miR-4661-5p	PAR-CLIP	22291592
MIRT497358	hsa-miR-4453	PAR-CLIP	22291592
MIRT497357	hsa-miR-4538	PAR-CLIP	22291592
MIRT497356	hsa-miR-1197	PAR-CLIP	22291592
MIRT497355	hsa-miR-494-3p	PAR-CLIP	22291592
MIRT497354	hsa-miR-5004-5p	PAR-CLIP	22291592
MIRT497353	hsa-miR-510-3p	PAR-CLIP	22291592
MIRT732867	hsa-miR-196a-5p	Luciferase reporter assay, qRT-PCR, Western blotting	33469841
MIRT722005	hsa-miR-6889-3p	HITS-CLIP	19536157
MIRT709670	hsa-miR-4641	HITS-CLIP	19536157
MIRT709669	hsa-miR-6778-3p	HITS-CLIP	19536157
MIRT709668	hsa-miR-6791-3p	HITS-CLIP	19536157
MIRT709667	hsa-miR-6829-3p	HITS-CLIP	19536157
MIRT709666	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT709665	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT709670	hsa-miR-4641	HITS-CLIP	19536157
MIRT709669	hsa-miR-6778-3p	HITS-CLIP	19536157
MIRT709668	hsa-miR-6791-3p	HITS-CLIP	19536157
MIRT709667	hsa-miR-6829-3p	HITS-CLIP	19536157
MIRT709666	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT709665	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT713443	hsa-miR-2278	HITS-CLIP	19536157
MIRT713442	hsa-miR-204-3p	HITS-CLIP	19536157
MIRT713441	hsa-miR-4646-5p	HITS-CLIP	19536157
MIRT713440	hsa-miR-3192-5p	HITS-CLIP	19536157
MIRT713439	hsa-miR-619-5p	HITS-CLIP	19536157
MIRT713438	hsa-miR-6506-5p	HITS-CLIP	19536157
MIRT713437	hsa-miR-3184-5p	HITS-CLIP	19536157
MIRT713436	hsa-miR-423-5p	HITS-CLIP	19536157
MIRT713435	hsa-miR-1914-3p	HITS-CLIP	19536157
MIRT713434	hsa-miR-5194	HITS-CLIP	19536157
MIRT713433	hsa-miR-6738-5p	HITS-CLIP	19536157
MIRT713432	hsa-miR-6878-5p	HITS-CLIP	19536157
MIRT713431	hsa-miR-6731-5p	HITS-CLIP	19536157
MIRT713430	hsa-miR-8085	HITS-CLIP	19536157
MIRT713429	hsa-miR-4710	HITS-CLIP	19536157
MIRT713428	hsa-miR-4314	HITS-CLIP	19536157
MIRT713427	hsa-miR-6734-5p	HITS-CLIP	19536157
MIRT713426	hsa-miR-30c-1-3p	HITS-CLIP	19536157
MIRT713425	hsa-miR-30c-2-3p	HITS-CLIP	19536157
MIRT713424	hsa-miR-6788-5p	HITS-CLIP	19536157
MIRT709670	hsa-miR-4641	HITS-CLIP	19536157
MIRT709669	hsa-miR-6778-3p	HITS-CLIP	19536157
MIRT709668	hsa-miR-6791-3p	HITS-CLIP	19536157
MIRT709667	hsa-miR-6829-3p	HITS-CLIP	19536157
MIRT709666	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT709665	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT709670	hsa-miR-4641	HITS-CLIP	19536157
MIRT709669	hsa-miR-6778-3p	HITS-CLIP	19536157
MIRT709668	hsa-miR-6791-3p	HITS-CLIP	19536157
MIRT709667	hsa-miR-6829-3p	HITS-CLIP	19536157
MIRT709666	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT709665	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT709664	hsa-miR-7108-3p	HITS-CLIP	19536157
MIRT709663	hsa-miR-4313	HITS-CLIP	19536157
MIRT615492	hsa-miR-656-3p	HITS-CLIP	19536157
MIRT615491	hsa-miR-1279	HITS-CLIP	19536157
MIRT618717	hsa-miR-5007-3p	HITS-CLIP	19536157
MIRT615490	hsa-miR-335-3p	HITS-CLIP	19536157
MIRT515853	hsa-miR-4789-3p	HITS-CLIP	21572407
MIRT515852	hsa-miR-3163	HITS-CLIP	21572407
MIRT515851	hsa-miR-410-3p	HITS-CLIP	21572407
MIRT515843	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT515850	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT707213	hsa-miR-4731-3p	HITS-CLIP	21572407
MIRT707212	hsa-miR-4801	HITS-CLIP	21572407
MIRT515849	hsa-miR-8485	HITS-CLIP	21572407
MIRT515848	hsa-miR-329-3p	HITS-CLIP	21572407
MIRT515847	hsa-miR-362-3p	HITS-CLIP	21572407
MIRT515846	hsa-miR-603	HITS-CLIP	21572407
MIRT515845	hsa-miR-3941	HITS-CLIP	21572407
MIRT515853	hsa-miR-4789-3p	HITS-CLIP	21572407
MIRT515843	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT515850	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT515858	hsa-miR-548aa	HITS-CLIP	23313552
MIRT515857	hsa-miR-548ap-3p	HITS-CLIP	23313552
MIRT515856	hsa-miR-548t-3p	HITS-CLIP	23313552
MIRT515855	hsa-miR-548at-3p	HITS-CLIP	23313552
MIRT515854	hsa-miR-548ay-3p	HITS-CLIP	23313552
MIRT515853	hsa-miR-4789-3p	HITS-CLIP	23313552
MIRT705817	hsa-miR-6813-3p	HITS-CLIP	23313552
MIRT515852	hsa-miR-3163	HITS-CLIP	23313552
MIRT515851	hsa-miR-410-3p	HITS-CLIP	23313552
MIRT515843	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT515850	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT515858	hsa-miR-548aa	HITS-CLIP	23313552
MIRT515857	hsa-miR-548ap-3p	HITS-CLIP	23313552
MIRT515856	hsa-miR-548t-3p	HITS-CLIP	23313552
MIRT684153	hsa-miR-548as-3p	HITS-CLIP	23313552
MIRT515855	hsa-miR-548at-3p	HITS-CLIP	23313552
MIRT515854	hsa-miR-548ay-3p	HITS-CLIP	23313552
MIRT515853	hsa-miR-4789-3p	HITS-CLIP	23313552
MIRT515852	hsa-miR-3163	HITS-CLIP	23313552
MIRT515851	hsa-miR-410-3p	HITS-CLIP	23313552
MIRT615492	hsa-miR-656-3p	HITS-CLIP	23824327
MIRT615491	hsa-miR-1279	HITS-CLIP	23824327
MIRT618717	hsa-miR-5007-3p	HITS-CLIP	23824327
MIRT615490	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT615492	hsa-miR-656-3p	HITS-CLIP	23824327
MIRT615491	hsa-miR-1279	HITS-CLIP	23824327
MIRT615490	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT515850	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT515858	hsa-miR-548aa	PAR-CLIP	23446348
MIRT515857	hsa-miR-548ap-3p	PAR-CLIP	23446348
MIRT515856	hsa-miR-548t-3p	PAR-CLIP	23446348
MIRT515855	hsa-miR-548at-3p	PAR-CLIP	23446348
MIRT515854	hsa-miR-548ay-3p	PAR-CLIP	23446348
MIRT515853	hsa-miR-4789-3p	PAR-CLIP	23446348
MIRT515852	hsa-miR-3163	PAR-CLIP	23446348
MIRT515851	hsa-miR-410-3p	PAR-CLIP	23446348
MIRT515850	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT515849	hsa-miR-8485	PAR-CLIP	23446348
MIRT515848	hsa-miR-329-3p	PAR-CLIP	23446348
MIRT515847	hsa-miR-362-3p	PAR-CLIP	23446348
MIRT515846	hsa-miR-603	PAR-CLIP	23446348
MIRT515845	hsa-miR-3941	PAR-CLIP	23446348
MIRT515844	hsa-miR-4789-5p	PAR-CLIP	23446348
MIRT515843	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT497359	hsa-miR-4661-5p	PAR-CLIP	22291592
MIRT497358	hsa-miR-4453	PAR-CLIP	22291592
MIRT497357	hsa-miR-4538	PAR-CLIP	22291592
MIRT497356	hsa-miR-1197	PAR-CLIP	22291592
MIRT497355	hsa-miR-494-3p	PAR-CLIP	22291592
MIRT497354	hsa-miR-5004-5p	PAR-CLIP	22291592
MIRT497353	hsa-miR-510-3p	PAR-CLIP	22291592
MIRT774571	hsa-miR-183	CLIP-seq
MIRT774572	hsa-miR-191	CLIP-seq
MIRT774573	hsa-miR-197	CLIP-seq
MIRT774574	hsa-miR-297	CLIP-seq
MIRT774575	hsa-miR-329	CLIP-seq
MIRT774576	hsa-miR-410	CLIP-seq
MIRT774577	hsa-miR-4283	CLIP-seq
MIRT774578	hsa-miR-4437	CLIP-seq
MIRT774579	hsa-miR-4796-5p	CLIP-seq
MIRT774580	hsa-miR-4802-3p	CLIP-seq
MIRT774581	hsa-miR-5095	CLIP-seq
MIRT774582	hsa-miR-552	CLIP-seq
MIRT774583	hsa-miR-567	CLIP-seq
MIRT774584	hsa-miR-586	CLIP-seq
MIRT2169399	hsa-miR-3176	CLIP-seq
MIRT2169400	hsa-miR-3922-3p	CLIP-seq
MIRT2169401	hsa-miR-4274	CLIP-seq
MIRT2169402	hsa-miR-4758-3p	CLIP-seq
MIRT2169403	hsa-miR-622	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001953	Process	Negative regulation of cell-matrix adhesion	IDA	16410724
GO:0005515	Function	Protein binding	IPI	17267690
GO:0005886	Component	Plasma membrane	IDA	14595118
GO:0005886	Component	Plasma membrane	IEA
GO:0005912	Component	Adherens junction	IBA
GO:0005912	Component	Adherens junction	IDA	14595118
GO:0005912	Component	Adherens junction	IEA
GO:0007155	Process	Cell adhesion	IEA
GO:0008013	Function	Beta-catenin binding	IBA
GO:0008013	Function	Beta-catenin binding	IPI	14595118
GO:0009898	Component	Cytoplasmic side of plasma membrane	IBA
GO:0009898	Component	Cytoplasmic side of plasma membrane	IDA	14595118
GO:0009986	Component	Cell surface	IDA	14595118
GO:0016020	Component	Membrane	IEA
GO:0016323	Component	Basolateral plasma membrane	IDA	16707570
GO:0016323	Component	Basolateral plasma membrane	IEA
GO:0016324	Component	Apical plasma membrane	IEA
GO:0019904	Function	Protein domain specific binding	IEA
GO:0030860	Process	Regulation of polarized epithelial cell differentiation	IDA	14595118
GO:0044291	Component	Cell-cell contact zone	IBA
GO:0044291	Component	Cell-cell contact zone	IDA	14595118
GO:0044877	Function	Protein-containing complex binding	IDA	14595118
GO:0061045	Process	Negative regulation of wound healing	IDA	16410724
GO:0070161	Component	Anchoring junction	IEA

Other IDs

• MIM: 610972
• HGNC: 30801
• e!Ensembl: ENSG00000196581

Protein

• UniProt ID: Q9UKB5
• Protein name: Adherens junction-associated protein 1 (Membrane protein shrew-1)
• Protein function: Plays a role in cell adhesion and cell migration.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15298	AJAP1_PANP_C	181 → 388	AJAP1/PANP C-terminus	Family

• Tissue specificity: TISSUE SPECIFICITY: Expressed in uterus and pancreas (at protein level). {ECO:0000269|PubMed:14595118}.
• Sequence:

  MWIQQLLGLSSMSIRWPGRPLGSHAWILIAMFQLAVDLPACEALGPGPEFWLLPRSPPRP
  PRLWSFRSGQPARVPAPVWSPRPPRVERIHGQMQMPRARRAHRPRDQAAALVPKAGLAKP
  PAAAKSSPSLASSSSSSSSAVAGGAPEQQALLRRGKRHLQGDGLSSFDSRGSRPTTETEF
  IAWGPTGDEEALESNTFPGVYGPTTVSILQTRKTTVAATTTTTTTATPMTLQTKGFTESL
  DPRRRIPGGVSTTEPSTSPSNNGEVTQPPRILGEASGLAVHQIITITVSLIMVIAALITT
  LVLKNCCAQSGNTRRNSHQRKTNQQEESCQNLTDFPSARVPSSLDIFTAYNETLQCSHEC
  VRASVPVYTDETLHSTTGEYKSTFNGNRPSSSDRHLIPVAFVSEKWFEISC

• Sequence length: 411