Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
55958
Gene name Gene Name - the full gene name approved by the HGNC.
Kelch like family member 9
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
KLHL9
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
9
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
9p21.3
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a protein that belongs to the kelch repeat-containing family, and contains an N-terminal BTB/POZ domain, a BACK domain and six C-terminal kelch repeats. The encoded protein is a component of a complex with cullin 3-based E3 ligase, which
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT038249 hsa-miR-330-5p CLASH 23622248
MIRT522823 hsa-miR-1277-5p HITS-CLIP 21572407
MIRT522822 hsa-miR-5580-3p HITS-CLIP 21572407
MIRT522821 hsa-miR-369-3p HITS-CLIP 21572407
MIRT522820 hsa-miR-5692b HITS-CLIP 21572407
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0004842 Function Ubiquitin-protein transferase activity IBA
GO:0004842 Function Ubiquitin-protein transferase activity IDA 17543862
GO:0005515 Function Protein binding IPI 17543862, 20554658, 21145461, 30190310, 34591642, 35512704
GO:0005829 Component Cytosol IEA
GO:0005829 Component Cytosol TAS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
611201 18732 ENSG00000198642
Protein
UniProt ID Q9P2J3
Protein name Kelch-like protein 9
Protein function Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dyn
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00651 BTB 40 148 BTB/POZ domain Domain
PF07707 BACK 154 255 BTB And C-terminal Kelch Domain
PF01344 Kelch_1 336 386 Kelch motif Repeat
PF01344 Kelch_1 388 433 Kelch motif Repeat
PF01344 Kelch_1 435 480 Kelch motif Repeat
PF01344 Kelch_1 483 532 Kelch motif Repeat
PF01344 Kelch_1 536 581 Kelch motif Repeat
Sequence
Sequence length 617
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  Ubiquitin mediated proteolysis   Neddylation
Antigen processing: Ubiquitination & Proteasome degradation
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