KLHL9 (kelch like family member 9)
|
Gene
Gene information from NCBI Gene database.
|
|
| Entrez ID | 55958 |
| Gene name | Kelch like family member 9 |
| Gene symbol | KLHL9 |
| Synonyms (NCBI Gene) |
-
|
| Chromosome | 9 |
| Chromosome location | 9p21.3 |
| Summary | This gene encodes a protein that belongs to the kelch repeat-containing family, and contains an N-terminal BTB/POZ domain, a BACK domain and six C-terminal kelch repeats. The encoded protein is a component of a complex with cullin 3-based E3 ligase, which |
|
miRNA
miRNA information provided by mirtarbase database.
542
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
|
Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
18
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
|
|||||||
|
|||||||
|
Protein
Protein information from UniProt database.
|
|||||||||||||||||||||||||||||||||||||||||
|
UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
|
Q9P2J3 | ||||||||||||||||||||||||||||||||||||||||
| Protein name | Kelch-like protein 9 | ||||||||||||||||||||||||||||||||||||||||
| Protein function | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dyn | ||||||||||||||||||||||||||||||||||||||||
| Family and domains |
Pfam
|
||||||||||||||||||||||||||||||||||||||||
| Sequence |
|
||||||||||||||||||||||||||||||||||||||||
| Sequence length | 617 | ||||||||||||||||||||||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||||||||||||||||||||||
|
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
|
|||||||||
|
|||||||||
|
Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
8
|
|||||||||||||||||
|
|||||||||||||||||
|
|||||||||||||||||