RNF114 (ring finger protein 114)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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55905 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Ring finger protein 114 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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RNF114 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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PSORS12, ZNF313 |
Chromosome
Chromosome number
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20 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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20q13.13 |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||||||||||||
UniProt ID | Q9Y508 | ||||||||||||||||||||
Protein name | E3 ubiquitin-protein ligase RNF114 (EC 2.3.2.27) (RING finger protein 114) (RING-type E3 ubiquitin transferase RNF114) (Zinc finger protein 228) (Zinc finger protein 313) | ||||||||||||||||||||
Protein function | E3 ubiquitin-protein ligase that promotes the ubiquitination of various substrates (PubMed:23645206, PubMed:25165885). In turn, participates in the regulation of many biological processes including cell cycle, apoptosis, osteoclastogenesis as we | ||||||||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Expressed in numerous tissues, including skin, CD4 lymphocytes and dendritic cells. Highest levels in testis. {ECO:0000269|PubMed:18364390}. | ||||||||||||||||||||
Sequence |
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Sequence length | 228 | ||||||||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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