Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	55892
Gene name Gene Name - the full gene name approved by the HGNC.	Myoneurin
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	MYNN
Synonyms (NCBI Gene) Gene synonyms aliases	OSZF, SBBIZ1, ZBTB31, ZNF902
Chromosome Chromosome number	3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	3q26.2
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the BTB/POZ and zinc finger domain-containing protein family that are involved in the control of gene expression. Alternative splicing results in multiple transcript variants and a pseudogene has been identified on chromosome

Show/Hide all(121)

miRTarBase ID	miRNA	Experiments	Reference
MIRT442893	hsa-miR-1179	PAR-CLIP	22100165
MIRT442892	hsa-miR-1253	PAR-CLIP	22100165
MIRT442893	hsa-miR-1179	PAR-CLIP	22100165
MIRT442892	hsa-miR-1253	PAR-CLIP	22100165
MIRT1169045	hsa-miR-1254	CLIP-seq
MIRT1169046	hsa-miR-1827	CLIP-seq
MIRT1169047	hsa-miR-2467-3p	CLIP-seq
MIRT1169048	hsa-miR-2861	CLIP-seq
MIRT1169049	hsa-miR-3116	CLIP-seq
MIRT1169050	hsa-miR-3120-5p	CLIP-seq
MIRT1169051	hsa-miR-3201	CLIP-seq
MIRT1169052	hsa-miR-342-5p	CLIP-seq
MIRT1169053	hsa-miR-3612	CLIP-seq
MIRT1169054	hsa-miR-3920	CLIP-seq
MIRT1169055	hsa-miR-4257	CLIP-seq
MIRT1169056	hsa-miR-4459	CLIP-seq
MIRT1169057	hsa-miR-4651	CLIP-seq
MIRT1169058	hsa-miR-4664-5p	CLIP-seq
MIRT1169059	hsa-miR-4695-5p	CLIP-seq
MIRT1169060	hsa-miR-4791	CLIP-seq
MIRT1169061	hsa-miR-541	CLIP-seq
MIRT1169062	hsa-miR-608	CLIP-seq
MIRT1169063	hsa-miR-650	CLIP-seq
MIRT1169064	hsa-miR-654-5p	CLIP-seq
MIRT1169065	hsa-miR-665	CLIP-seq
MIRT1169066	hsa-miR-125a-3p	CLIP-seq
MIRT1169067	hsa-miR-1271	CLIP-seq
MIRT1169068	hsa-miR-1273d	CLIP-seq
MIRT1169069	hsa-miR-1273e	CLIP-seq
MIRT1169070	hsa-miR-153	CLIP-seq
MIRT1169071	hsa-miR-181a	CLIP-seq
MIRT1169072	hsa-miR-181b	CLIP-seq
MIRT1169073	hsa-miR-181c	CLIP-seq
MIRT1169074	hsa-miR-181d	CLIP-seq
MIRT1169075	hsa-miR-182	CLIP-seq
MIRT1169046	hsa-miR-1827	CLIP-seq
MIRT1169076	hsa-miR-1912	CLIP-seq
MIRT1169077	hsa-miR-23a	CLIP-seq
MIRT1169078	hsa-miR-23b	CLIP-seq
MIRT1169079	hsa-miR-23c	CLIP-seq
MIRT1169047	hsa-miR-2467-3p	CLIP-seq
MIRT1169080	hsa-miR-2964a-3p	CLIP-seq
MIRT1169081	hsa-miR-302f	CLIP-seq
MIRT1169082	hsa-miR-3151	CLIP-seq
MIRT1169083	hsa-miR-3157-3p	CLIP-seq
MIRT1169084	hsa-miR-3163	CLIP-seq
MIRT1169085	hsa-miR-3188	CLIP-seq
MIRT1169086	hsa-miR-323b-3p	CLIP-seq
MIRT1169087	hsa-miR-331-5p	CLIP-seq
MIRT1169088	hsa-miR-337-3p	CLIP-seq
MIRT1169053	hsa-miR-3612	CLIP-seq
MIRT1169089	hsa-miR-3664-3p	CLIP-seq
MIRT1169090	hsa-miR-3929	CLIP-seq
MIRT1169091	hsa-miR-3934	CLIP-seq
MIRT1169055	hsa-miR-4257	CLIP-seq
MIRT1169092	hsa-miR-4262	CLIP-seq
MIRT1169093	hsa-miR-4265	CLIP-seq
MIRT1169094	hsa-miR-4296	CLIP-seq
MIRT1169095	hsa-miR-4312	CLIP-seq
MIRT1169096	hsa-miR-4322	CLIP-seq
MIRT1169097	hsa-miR-4419b	CLIP-seq
MIRT1169098	hsa-miR-4433	CLIP-seq
MIRT1169099	hsa-miR-4447	CLIP-seq
MIRT1169056	hsa-miR-4459	CLIP-seq
MIRT1169100	hsa-miR-4472	CLIP-seq
MIRT1169101	hsa-miR-4478	CLIP-seq
MIRT1169102	hsa-miR-4634	CLIP-seq
MIRT1169103	hsa-miR-4643	CLIP-seq
MIRT1169104	hsa-miR-4649-3p	CLIP-seq
MIRT1169105	hsa-miR-466	CLIP-seq
MIRT1169059	hsa-miR-4695-5p	CLIP-seq
MIRT1169106	hsa-miR-4724-5p	CLIP-seq
MIRT1169107	hsa-miR-4743	CLIP-seq
MIRT1169108	hsa-miR-4768-3p	CLIP-seq
MIRT1169109	hsa-miR-4789-3p	CLIP-seq
MIRT1169110	hsa-miR-485-5p	CLIP-seq
MIRT1169111	hsa-miR-491-5p	CLIP-seq
MIRT1169112	hsa-miR-510	CLIP-seq
MIRT1169113	hsa-miR-512-5p	CLIP-seq
MIRT1169114	hsa-miR-577	CLIP-seq
MIRT1169063	hsa-miR-650	CLIP-seq
MIRT1169065	hsa-miR-665	CLIP-seq
MIRT1169115	hsa-miR-764	CLIP-seq
MIRT1169116	hsa-miR-874	CLIP-seq
MIRT1169117	hsa-miR-938	CLIP-seq
MIRT1169118	hsa-miR-96	CLIP-seq
MIRT1551521	hsa-miR-607	CLIP-seq
MIRT1169066	hsa-miR-125a-3p	CLIP-seq
MIRT1169091	hsa-miR-3934	CLIP-seq
MIRT1169056	hsa-miR-4459	CLIP-seq
MIRT1169059	hsa-miR-4695-5p	CLIP-seq
MIRT1169107	hsa-miR-4743	CLIP-seq
MIRT2048622	hsa-miR-4803	CLIP-seq
MIRT2048623	hsa-miR-515-5p	CLIP-seq
MIRT1169115	hsa-miR-764	CLIP-seq
MIRT2048624	hsa-miR-766	CLIP-seq
MIRT2576337	hsa-miR-3646	CLIP-seq
MIRT2576338	hsa-miR-501-3p	CLIP-seq
MIRT2576339	hsa-miR-502-3p	CLIP-seq
MIRT2576337	hsa-miR-3646	CLIP-seq
MIRT2576337	hsa-miR-3646	CLIP-seq
MIRT2576338	hsa-miR-501-3p	CLIP-seq
MIRT2576339	hsa-miR-502-3p	CLIP-seq
MIRT2685657	hsa-miR-105	CLIP-seq
MIRT2576337	hsa-miR-3646	CLIP-seq
MIRT2685658	hsa-miR-3908	CLIP-seq
MIRT2685659	hsa-miR-3925-3p	CLIP-seq
MIRT2685660	hsa-miR-3942-5p	CLIP-seq
MIRT2685661	hsa-miR-4517	CLIP-seq
MIRT2685662	hsa-miR-4703-5p	CLIP-seq
MIRT2685663	hsa-miR-4756-3p	CLIP-seq
MIRT2685664	hsa-miR-4766-3p	CLIP-seq
MIRT2685665	hsa-miR-4790-3p	CLIP-seq
MIRT2576338	hsa-miR-501-3p	CLIP-seq
MIRT2576339	hsa-miR-502-3p	CLIP-seq
MIRT2048623	hsa-miR-515-5p	CLIP-seq
MIRT2685666	hsa-miR-587	CLIP-seq
MIRT2685667	hsa-miR-591	CLIP-seq
MIRT2048624	hsa-miR-766	CLIP-seq
MIRT2685668	hsa-miR-888	CLIP-seq
MIRT2685669	hsa-miR-889	CLIP-seq

Show/Hide all(10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	32296183, 32814053
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:1990830	Process	Cellular response to leukemia inhibitory factor	IEA

MIM	HGNC	e!Ensembl
606042	14955	ENSG00000085274

Protein

UniProt ID

Q9NPC7

Protein name

Myoneurin (Zinc finger and BTB domain-containing protein 31)

PDB

2VPK

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00651	BTB	14 → 118	BTB/POZ domain	Domain
PF00096	zf-C2H2	303 → 324	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	330 → 352	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	387 → 409	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	415 → 437	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	443 → 465	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	471 → 493	Zinc finger, C2H2 type	Domain
PF13912	zf-C2H2_6	499 → 524		Domain

Tissue specificity

TISSUE SPECIFICITY: Mainly expressed in the neuromuscular system. Located in and around synaptic myonuclei in adult muscle. Expression is dysregulated after nerve injury. Also found in the testis, ovary and placenta. {ECO:0000269|PubMed:10873615, ECO:0000

Sequence

MQYSHHCEHLLERLNKQREAGFLCDCTIVIGEFQFKAHRNVLASFSEYFGAIYRSTSENN
VFLDQSQVKADGFQKLLEFIYTGTLNLDSWNVKEIHQAADYLKVEEVVTKCKIKMEDFAF
IANPSSTEISSITGNIELNQQTCLLTLRDYNNREKSEVSTDLIQANPKQGALAKKSSQTK
KKKKAFNSPKTGQNKTVQYPSDILENASVELFLDANKLPTPVVEQVAQINDNSELELTSV
VENTFPAQDIVHTVTVKRKRGKSQPNCALKEHSMSNIASVKSPYEAENSGEELDQRYSKA
KPMCNTCGKVFSEASSLRRHMRIHKGVKPYVCHLCGKAFTQCNQLKTHVRTHTGEKPYKC
ELCDKGFAQKCQLVFHSRMHHGEEKPYKCDVCNLQFATSSNLKIHARKHSGEKPYVCDRC
GQRFAQASTLTYHVRRHTGEKPYVCDTCGKAFAVSSSLITHSRKHTGEKPYICGICGKSF
ISSGELNKHFRSHTGERPFICELCGNSYTDIKNLKKHKTKVHSGADKTLDSSAEDHTLSE
QDSIQKSPLSETMDVKPSDMTLPLALPLGTEDHHMLLPVTDTQSPTSDTLLRSTVNGYSE
PQLIFLQQLY

Sequence length

610

Interactions

View interactions

Show/Hide Unknown Diseases (11)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Celiac disease	Celiac disease	N/A	N/A	GWAS
Colorectal Cancer	Colorectal cancer	N/A	N/A	GWAS
Glioma	Glioma	N/A	N/A	GWAS
Lung adenocarcinoma	Lung adenocarcinoma (conditioned on cigarettes per day), Lung adenocarcinoma	N/A	N/A	GWAS
Lymphocytic Leukemia	Chronic lymphocytic leukemia	N/A	N/A	GWAS
Lymphoid leukemia	Leukemia (PheCode 204)	N/A	N/A	GWAS
Multiple myeloma	Multiple myeloma	N/A	N/A	GWAS
Multiple Sclerosis	Multiple sclerosis	N/A	N/A	GWAS
Osteomyelitis	chronic osteomyelitis	N/A	N/A	ClinVar
Systemic lupus erythematosus	Systemic lupus erythematosus	N/A	N/A	GWAS
Uterine Fibroids	Uterine fibroids	N/A	N/A	GWAS

Show/Hide Text Mining Associations (24)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenoma	Associate	21708826, 22999960, 24875374
Alzheimer Disease	Associate	32309439
Atherosclerosis	Associate	32486379
Carcinogenesis	Associate	24163127
Carcinoma Pancreatic Ductal	Associate	32312758
Cerebral Infarction	Associate	28057933
Cerebral Small Vessel Diseases	Associate	30769869
Colorectal Neoplasms	Associate	20972440, 21708826, 22999960, 24875374, 24978480, 30518759
Coronary Disease	Associate	24904205
Death	Associate	33763035
Diabetes Mellitus Type 2	Associate	32296102
Glioma	Associate	40474102
Heart Failure	Associate	33763035
Hematologic Neoplasms	Associate	23955597
Leukocyte Disorders	Associate	31388112
Lupus Erythematosus Systemic	Associate	28108556
Meningioma	Associate	30796745
Monoclonal Gammopathy of Undetermined Significance	Associate	24449210
Multiple Myeloma	Associate	23955597, 24449210, 32433745
Neoplasms	Associate	30518759, 31988393
Obesity	Associate	24455749
Ovarian Neoplasms	Associate	20386695
Polyps	Associate	24875374
Urinary Bladder Neoplasms	Associate	24163127, 30120764

MYNN (myoneurin)