Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	55789
Gene name Gene Name - the full gene name approved by the HGNC.	DEP domain containing 1B
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	DEPDC1B
Synonyms (NCBI Gene) Gene synonyms aliases	BRCC3, XTP1
Chromosome Chromosome number	5
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	5q12.1

Show/Hide all(166)

miRTarBase ID	miRNA	Experiments	Reference
MIRT020076	hsa-miR-361-5p	Sequencing	20371350
MIRT564279	hsa-miR-548ac	PAR-CLIP	20371350
MIRT564278	hsa-miR-548bb-3p	PAR-CLIP	20371350
MIRT564277	hsa-miR-548d-3p	PAR-CLIP	20371350
MIRT564276	hsa-miR-548h-3p	PAR-CLIP	20371350
MIRT564275	hsa-miR-548z	PAR-CLIP	20371350
MIRT564274	hsa-miR-548ae-3p	PAR-CLIP	20371350
MIRT564273	hsa-miR-548ah-3p	PAR-CLIP	20371350
MIRT564272	hsa-miR-548aj-3p	PAR-CLIP	20371350
MIRT564271	hsa-miR-548am-3p	PAR-CLIP	20371350
MIRT564270	hsa-miR-548aq-3p	PAR-CLIP	20371350
MIRT564269	hsa-miR-548j-3p	PAR-CLIP	20371350
MIRT564268	hsa-miR-548x-3p	PAR-CLIP	20371350
MIRT564267	hsa-miR-548a-3p	PAR-CLIP	20371350
MIRT564266	hsa-miR-548ar-3p	PAR-CLIP	20371350
MIRT564265	hsa-miR-548az-3p	PAR-CLIP	20371350
MIRT564264	hsa-miR-548e-3p	PAR-CLIP	20371350
MIRT564263	hsa-miR-548f-3p	PAR-CLIP	20371350
MIRT313866	hsa-miR-4282	PAR-CLIP	20371350
MIRT564262	hsa-miR-3617-5p	PAR-CLIP	20371350
MIRT564261	hsa-miR-641	PAR-CLIP	20371350
MIRT564260	hsa-miR-3942-5p	PAR-CLIP	20371350
MIRT564259	hsa-miR-4703-5p	PAR-CLIP	20371350
MIRT564258	hsa-miR-455-5p	PAR-CLIP	20371350
MIRT564257	hsa-miR-95-5p	PAR-CLIP	20371350
MIRT564256	hsa-miR-103a-3p	PAR-CLIP	20371350
MIRT564255	hsa-miR-107	PAR-CLIP	20371350
MIRT564254	hsa-miR-3944-5p	PAR-CLIP	20371350
MIRT564253	hsa-miR-143-5p	PAR-CLIP	20371350
MIRT564279	hsa-miR-548ac	PAR-CLIP	20371350
MIRT564278	hsa-miR-548bb-3p	PAR-CLIP	20371350
MIRT564277	hsa-miR-548d-3p	PAR-CLIP	20371350
MIRT564276	hsa-miR-548h-3p	PAR-CLIP	20371350
MIRT564275	hsa-miR-548z	PAR-CLIP	20371350
MIRT564274	hsa-miR-548ae-3p	PAR-CLIP	20371350
MIRT564273	hsa-miR-548ah-3p	PAR-CLIP	20371350
MIRT564272	hsa-miR-548aj-3p	PAR-CLIP	20371350
MIRT564271	hsa-miR-548am-3p	PAR-CLIP	20371350
MIRT564270	hsa-miR-548aq-3p	PAR-CLIP	20371350
MIRT564269	hsa-miR-548j-3p	PAR-CLIP	20371350
MIRT564268	hsa-miR-548x-3p	PAR-CLIP	20371350
MIRT564267	hsa-miR-548a-3p	PAR-CLIP	20371350
MIRT564266	hsa-miR-548ar-3p	PAR-CLIP	20371350
MIRT564265	hsa-miR-548az-3p	PAR-CLIP	20371350
MIRT564264	hsa-miR-548e-3p	PAR-CLIP	20371350
MIRT564263	hsa-miR-548f-3p	PAR-CLIP	20371350
MIRT313866	hsa-miR-4282	PAR-CLIP	20371350
MIRT564262	hsa-miR-3617-5p	PAR-CLIP	20371350
MIRT564261	hsa-miR-641	PAR-CLIP	20371350
MIRT564260	hsa-miR-3942-5p	PAR-CLIP	20371350
MIRT564259	hsa-miR-4703-5p	PAR-CLIP	20371350
MIRT564258	hsa-miR-455-5p	PAR-CLIP	20371350
MIRT564257	hsa-miR-95-5p	PAR-CLIP	20371350
MIRT564256	hsa-miR-103a-3p	PAR-CLIP	20371350
MIRT564255	hsa-miR-107	PAR-CLIP	20371350
MIRT564254	hsa-miR-3944-5p	PAR-CLIP	20371350
MIRT564253	hsa-miR-143-5p	PAR-CLIP	20371350
MIRT932937	hsa-miR-101	CLIP-seq
MIRT932938	hsa-miR-128	CLIP-seq
MIRT932939	hsa-miR-132	CLIP-seq
MIRT932940	hsa-miR-1912	CLIP-seq
MIRT932941	hsa-miR-194	CLIP-seq
MIRT932942	hsa-miR-199a-5p	CLIP-seq
MIRT932943	hsa-miR-199b-5p	CLIP-seq
MIRT932944	hsa-miR-212	CLIP-seq
MIRT932945	hsa-miR-224	CLIP-seq
MIRT932946	hsa-miR-27a	CLIP-seq
MIRT932947	hsa-miR-27b	CLIP-seq
MIRT932948	hsa-miR-3130-5p	CLIP-seq
MIRT932949	hsa-miR-4482	CLIP-seq
MIRT932950	hsa-miR-4700-3p	CLIP-seq
MIRT932951	hsa-miR-4711-3p	CLIP-seq
MIRT932952	hsa-miR-4768-3p	CLIP-seq
MIRT932953	hsa-miR-539	CLIP-seq
MIRT932954	hsa-miR-802	CLIP-seq
MIRT932937	hsa-miR-101	CLIP-seq
MIRT932955	hsa-miR-1251	CLIP-seq
MIRT932956	hsa-miR-1273d	CLIP-seq
MIRT932938	hsa-miR-128	CLIP-seq
MIRT932957	hsa-miR-1297	CLIP-seq
MIRT932939	hsa-miR-132	CLIP-seq
MIRT932958	hsa-miR-1323	CLIP-seq
MIRT932959	hsa-miR-145	CLIP-seq
MIRT932960	hsa-miR-186	CLIP-seq
MIRT932940	hsa-miR-1912	CLIP-seq
MIRT932941	hsa-miR-194	CLIP-seq
MIRT932942	hsa-miR-199a-5p	CLIP-seq
MIRT932943	hsa-miR-199b-5p	CLIP-seq
MIRT932944	hsa-miR-212	CLIP-seq
MIRT932945	hsa-miR-224	CLIP-seq
MIRT932961	hsa-miR-26a	CLIP-seq
MIRT932962	hsa-miR-26b	CLIP-seq
MIRT932946	hsa-miR-27a	CLIP-seq
MIRT932947	hsa-miR-27b	CLIP-seq
MIRT932963	hsa-miR-29a	CLIP-seq
MIRT932964	hsa-miR-29b	CLIP-seq
MIRT932965	hsa-miR-29c	CLIP-seq
MIRT932948	hsa-miR-3130-5p	CLIP-seq
MIRT932966	hsa-miR-33a	CLIP-seq
MIRT932967	hsa-miR-33b	CLIP-seq
MIRT932968	hsa-miR-3545-5p	CLIP-seq
MIRT932969	hsa-miR-371b-5p	CLIP-seq
MIRT932970	hsa-miR-4257	CLIP-seq
MIRT932971	hsa-miR-4272	CLIP-seq
MIRT932972	hsa-miR-4465	CLIP-seq
MIRT932949	hsa-miR-4482	CLIP-seq
MIRT932973	hsa-miR-4521	CLIP-seq
MIRT932974	hsa-miR-4709-5p	CLIP-seq
MIRT932951	hsa-miR-4711-3p	CLIP-seq
MIRT932975	hsa-miR-4789-5p	CLIP-seq
MIRT932976	hsa-miR-511	CLIP-seq
MIRT932977	hsa-miR-548o	CLIP-seq
MIRT932978	hsa-miR-660	CLIP-seq
MIRT932954	hsa-miR-802	CLIP-seq
MIRT932979	hsa-miR-888	CLIP-seq
MIRT932975	hsa-miR-4789-5p	CLIP-seq
MIRT932937	hsa-miR-101	CLIP-seq
MIRT2211630	hsa-miR-124	CLIP-seq
MIRT2211631	hsa-miR-1265	CLIP-seq
MIRT932938	hsa-miR-128	CLIP-seq
MIRT932957	hsa-miR-1297	CLIP-seq
MIRT932939	hsa-miR-132	CLIP-seq
MIRT932958	hsa-miR-1323	CLIP-seq
MIRT2211632	hsa-miR-142-5p	CLIP-seq
MIRT932940	hsa-miR-1912	CLIP-seq
MIRT932941	hsa-miR-194	CLIP-seq
MIRT2211633	hsa-miR-199a-3p	CLIP-seq
MIRT932942	hsa-miR-199a-5p	CLIP-seq
MIRT2211634	hsa-miR-199b-3p	CLIP-seq
MIRT932943	hsa-miR-199b-5p	CLIP-seq
MIRT932944	hsa-miR-212	CLIP-seq
MIRT932945	hsa-miR-224	CLIP-seq
MIRT2211635	hsa-miR-2392	CLIP-seq
MIRT932961	hsa-miR-26a	CLIP-seq
MIRT932962	hsa-miR-26b	CLIP-seq
MIRT932946	hsa-miR-27a	CLIP-seq
MIRT932947	hsa-miR-27b	CLIP-seq
MIRT2211636	hsa-miR-3074-3p	CLIP-seq
MIRT2211637	hsa-miR-3129-5p	CLIP-seq
MIRT932948	hsa-miR-3130-5p	CLIP-seq
MIRT2211638	hsa-miR-3171	CLIP-seq
MIRT2211639	hsa-miR-340	CLIP-seq
MIRT2211640	hsa-miR-3714	CLIP-seq
MIRT932969	hsa-miR-371b-5p	CLIP-seq
MIRT2211641	hsa-miR-3910	CLIP-seq
MIRT932971	hsa-miR-4272	CLIP-seq
MIRT932972	hsa-miR-4465	CLIP-seq
MIRT2211642	hsa-miR-4474-5p	CLIP-seq
MIRT932949	hsa-miR-4482	CLIP-seq
MIRT932951	hsa-miR-4711-3p	CLIP-seq
MIRT932975	hsa-miR-4789-5p	CLIP-seq
MIRT2211643	hsa-miR-491-3p	CLIP-seq
MIRT2211644	hsa-miR-506	CLIP-seq
MIRT932976	hsa-miR-511	CLIP-seq
MIRT2211645	hsa-miR-548ae	CLIP-seq
MIRT2211646	hsa-miR-548aj	CLIP-seq
MIRT2211647	hsa-miR-548am	CLIP-seq
MIRT932977	hsa-miR-548o	CLIP-seq
MIRT2211648	hsa-miR-548x	CLIP-seq
MIRT932954	hsa-miR-802	CLIP-seq
MIRT932979	hsa-miR-888	CLIP-seq
MIRT2211649	hsa-miR-936	CLIP-seq
MIRT932958	hsa-miR-1323	CLIP-seq
MIRT932969	hsa-miR-371b-5p	CLIP-seq
MIRT932977	hsa-miR-548o	CLIP-seq
MIRT932979	hsa-miR-888	CLIP-seq

Show/Hide all(8)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005096	Function	GTPase activator activity	IEA
GO:0005829	Component	Cytosol	TAS
GO:0016477	Process	Cell migration	IMP	24971537
GO:0030177	Process	Positive regulation of Wnt signaling pathway	IBA	21873635
GO:0030177	Process	Positive regulation of Wnt signaling pathway	IMP	24971537
GO:0035556	Process	Intracellular signal transduction	IEA
GO:0043547	Process	Positive regulation of GTPase activity	IEA
GO:0051056	Process	Regulation of small GTPase mediated signal transduction	TAS

MIM	HGNC	e!Ensembl
616073	24902	ENSG00000035499

Protein

UniProt ID

Q8WUY9

Protein name

DEP domain-containing protein 1B (HBV X-transactivated gene 8 protein) (HBV XAg-transactivated protein 8)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00610	DEP	27 → 106	Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)	Domain
PF00620	RhoGAP	266 → 346	RhoGAP domain	Domain

Sequence

MEHRIVGPGPYRATRLWNETVELFRAKMPLRKHRCRFKSYEHCFTAAEAVDWLHELLRCS
QNFGPEVTRKQTVQLLKKFLKNHVIEDIKGKWGEEDFEDNRHLYRFPPSSPLKPYPKKPP
NQKDVIKFPEWNDLPPGTSQENIPVRPVVMNSEMWYKRHSIAIGEVPACRLVHRRQLTEA
NVEEIWKSMTLSYLQKILGLDSLEEVLDVKLVNSKFIIHNVYSVSKQGVVILDDKSKELP
HWVLSAMKCLANWPNCSDLKQPMYLGFEKDVFKTIADYYGHLKEPLLTFHLFDAFVSVLG
LLQKEKVAVEAFQICCLLLPPENRRKLQLLMRMMARICLNKEMPPLCDGFGTRTLMVQTF
SRCILCSKDEVDLDELLAARLVTFLMDNYQEILKVPLALQTSIEERVAHLRRVQIKYPGA
DMDITLSAPSFCRQISPEEFEYQRSYGSQEPLAALLEEVITDAKLSNKEKKKKLKQFQKS
YPEVYQERFPTPESAALLFPEKPKPKPQLLMWALKKPFQPFQRTRSFRM

Sequence length

529

Interactions

View interactions

	Reactome
			Rho GTPase cycle

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Schizophrenia	Schizophrenia			GWAS

Show/Hide Text Mining Associations (15)

Disease Name	Relationship Type	References
Associations from Text Mining
Anti Neutrophil Cytoplasmic Antibody Associated Vasculitis	Stimulate	39287711
Breast Neoplasms	Associate	37642235
Calcinosis Cutis	Stimulate	35088579
Carcinoma Hepatocellular	Stimulate	34983303
Carcinoma Hepatocellular	Associate	36785674
Colonic Neoplasms	Associate	35392038
Colorectal Neoplasms	Stimulate	36016512
Glioma	Stimulate	36394729
Melanoma	Associate	35088579
Melanoma Cutaneous Malignant	Associate	35088579
Mouth Neoplasms	Associate	25091805
Neoplasm Metastasis	Associate	35088579, 37642235
Neoplasms	Associate	20923822, 34983303, 36016512, 36394729
Precancerous Conditions	Associate	37642235
Prostatic Neoplasms	Associate	32664150

DEPDC1B (DEP domain containing 1B)