Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	55745
Gene name Gene Name - the full gene name approved by the HGNC.	Adaptor related protein complex 5 subunit mu 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	AP5M1
Synonyms (NCBI Gene) Gene synonyms aliases	C14orf108, MUDENG, Mu5, MuD
Chromosome Chromosome number	14
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	14q22.3

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miRTarBase ID	miRNA	Experiments	Reference
MIRT016437	hsa-miR-193b-3p	Microarray	20304954
MIRT030579	hsa-miR-24-3p	Microarray	19748357
MIRT719645	hsa-miR-5571-5p	HITS-CLIP	19536157
MIRT719644	hsa-miR-3613-3p	HITS-CLIP	19536157
MIRT719643	hsa-miR-8060	HITS-CLIP	19536157
MIRT719642	hsa-miR-7110-3p	HITS-CLIP	19536157
MIRT719641	hsa-miR-6817-3p	HITS-CLIP	19536157
MIRT719640	hsa-miR-3612	HITS-CLIP	19536157
MIRT719639	hsa-miR-650	HITS-CLIP	19536157
MIRT719638	hsa-miR-7154-5p	HITS-CLIP	19536157
MIRT719637	hsa-miR-6873-3p	HITS-CLIP	19536157
MIRT719636	hsa-miR-4768-5p	HITS-CLIP	19536157
MIRT719635	hsa-miR-6833-3p	HITS-CLIP	19536157
MIRT624719	hsa-miR-8485	HITS-CLIP	19536157
MIRT624718	hsa-miR-4789-3p	HITS-CLIP	19536157
MIRT624717	hsa-miR-181a-5p	HITS-CLIP	19536157
MIRT624716	hsa-miR-181b-5p	HITS-CLIP	19536157
MIRT624715	hsa-miR-181c-5p	HITS-CLIP	19536157
MIRT624714	hsa-miR-181d-5p	HITS-CLIP	19536157
MIRT624713	hsa-miR-4262	HITS-CLIP	19536157
MIRT385404	hsa-miR-8063	HITS-CLIP	19536157
MIRT385403	hsa-miR-4698	HITS-CLIP	19536157
MIRT715591	hsa-miR-8064	HITS-CLIP	19536157
MIRT669534	hsa-miR-6882-5p	HITS-CLIP	23824327
MIRT669533	hsa-miR-345-5p	HITS-CLIP	23824327
MIRT669532	hsa-miR-4513	HITS-CLIP	23824327
MIRT669531	hsa-miR-6855-3p	HITS-CLIP	23824327
MIRT669530	hsa-miR-6857-3p	HITS-CLIP	23824327
MIRT669529	hsa-miR-134-5p	HITS-CLIP	23824327
MIRT669528	hsa-miR-3118	HITS-CLIP	23824327
MIRT669527	hsa-miR-4795-3p	HITS-CLIP	23824327
MIRT669526	hsa-miR-3136-5p	HITS-CLIP	23824327
MIRT669525	hsa-miR-4439	HITS-CLIP	23824327
MIRT669524	hsa-let-7c-3p	HITS-CLIP	23824327
MIRT624719	hsa-miR-8485	HITS-CLIP	23824327
MIRT624718	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT624717	hsa-miR-181a-5p	HITS-CLIP	23824327
MIRT624716	hsa-miR-181b-5p	HITS-CLIP	23824327
MIRT624715	hsa-miR-181c-5p	HITS-CLIP	23824327
MIRT624714	hsa-miR-181d-5p	HITS-CLIP	23824327
MIRT624713	hsa-miR-4262	HITS-CLIP	23824327
MIRT385404	hsa-miR-8063	HITS-CLIP	23824327
MIRT385403	hsa-miR-4698	HITS-CLIP	23824327
MIRT719645	hsa-miR-5571-5p	HITS-CLIP	19536157
MIRT719644	hsa-miR-3613-3p	HITS-CLIP	19536157
MIRT719643	hsa-miR-8060	HITS-CLIP	19536157
MIRT719642	hsa-miR-7110-3p	HITS-CLIP	19536157
MIRT719641	hsa-miR-6817-3p	HITS-CLIP	19536157
MIRT719640	hsa-miR-3612	HITS-CLIP	19536157
MIRT719639	hsa-miR-650	HITS-CLIP	19536157
MIRT719638	hsa-miR-7154-5p	HITS-CLIP	19536157
MIRT719637	hsa-miR-6873-3p	HITS-CLIP	19536157
MIRT719636	hsa-miR-4768-5p	HITS-CLIP	19536157
MIRT719635	hsa-miR-6833-3p	HITS-CLIP	19536157
MIRT624719	hsa-miR-8485	HITS-CLIP	19536157
MIRT624718	hsa-miR-4789-3p	HITS-CLIP	19536157
MIRT624717	hsa-miR-181a-5p	HITS-CLIP	19536157
MIRT624716	hsa-miR-181b-5p	HITS-CLIP	19536157
MIRT624715	hsa-miR-181c-5p	HITS-CLIP	19536157
MIRT624714	hsa-miR-181d-5p	HITS-CLIP	19536157
MIRT624713	hsa-miR-4262	HITS-CLIP	19536157
MIRT385404	hsa-miR-8063	HITS-CLIP	19536157
MIRT385403	hsa-miR-4698	HITS-CLIP	19536157
MIRT715591	hsa-miR-8064	HITS-CLIP	19536157
MIRT669534	hsa-miR-6882-5p	HITS-CLIP	23824327
MIRT669533	hsa-miR-345-5p	HITS-CLIP	23824327
MIRT669532	hsa-miR-4513	HITS-CLIP	23824327
MIRT669531	hsa-miR-6855-3p	HITS-CLIP	23824327
MIRT669530	hsa-miR-6857-3p	HITS-CLIP	23824327
MIRT669529	hsa-miR-134-5p	HITS-CLIP	23824327
MIRT669528	hsa-miR-3118	HITS-CLIP	23824327
MIRT669527	hsa-miR-4795-3p	HITS-CLIP	23824327
MIRT669526	hsa-miR-3136-5p	HITS-CLIP	23824327
MIRT669525	hsa-miR-4439	HITS-CLIP	23824327
MIRT669524	hsa-let-7c-3p	HITS-CLIP	23824327
MIRT624719	hsa-miR-8485	HITS-CLIP	23824327
MIRT624718	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT624717	hsa-miR-181a-5p	HITS-CLIP	23824327
MIRT624716	hsa-miR-181b-5p	HITS-CLIP	23824327
MIRT624715	hsa-miR-181c-5p	HITS-CLIP	23824327
MIRT624714	hsa-miR-181d-5p	HITS-CLIP	23824327
MIRT624713	hsa-miR-4262	HITS-CLIP	23824327
MIRT385404	hsa-miR-8063	HITS-CLIP	23824327
MIRT385403	hsa-miR-4698	HITS-CLIP	23824327

Show/Hide all(23)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	22022230
GO:0005737	Component	Cytoplasm	IEA
GO:0005764	Component	Lysosome	IBA
GO:0005764	Component	Lysosome	IDA	22022230
GO:0005764	Component	Lysosome	IEA
GO:0005765	Component	Lysosomal membrane	IEA
GO:0005768	Component	Endosome	IEA
GO:0005770	Component	Late endosome	IBA
GO:0005770	Component	Late endosome	IDA	22022230
GO:0005770	Component	Late endosome	NAS	22022230
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	IDA	22022230
GO:0005829	Component	Cytosol	IEA
GO:0015031	Process	Protein transport	IEA
GO:0016020	Component	Membrane	IDA	22022230
GO:0016020	Component	Membrane	IEA
GO:0016192	Process	Vesicle-mediated transport	NAS	22022230
GO:0016197	Process	Endosomal transport	IBA
GO:0016197	Process	Endosomal transport	IMP	22022230
GO:0030119	Component	AP-type membrane coat adaptor complex	IBA
GO:0030119	Component	AP-type membrane coat adaptor complex	IDA	22022230
GO:0031902	Component	Late endosome membrane	IEA
GO:0044599	Component	AP-5 adaptor complex	NAS	22022230

MIM	HGNC	e!Ensembl
614368	20192	ENSG00000053770

Protein

UniProt ID

Q9H0R1

Protein name

AP-5 complex subunit mu-1 (Adaptor-related protein complex 5 subunit mu-1) (Mu5) (Mu-2-related death-inducing protein) (MuD) (Putative HIV-1 infection-related protein)

Protein function

As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed:18395520, it may play a role in cell death.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00928	Adap_comp_sub	196 → 476	Adaptor complexes medium subunit family	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in various tumor cell lines including Jurkat, Hep-G2 and HeLa. {ECO:0000269|PubMed:18395520}.

Sequence

MAQRAVWLISHEPGTPLCGTVRFSRRYPTVEKRARVFNGASYVPVPEDGPFLKALLFELR
LLDDDKDFVESRDSCSRINKTSIYGLLIGGEELWPVVAFLKNDMIYACVPLVEQTLSPRP
PLISVSGVSQGFEFLFGIQDFLYSGQKNDSELNTKLSQLPDLLLQACPFGTLLDANLQNS
LDNTNFASVTQPQKQPAWKTGTYKGKPQVSISITEKVKSMQYDKQGIADTWQVVGTVTCK
CDLEGIMPNVTISLSLPTNGSPLQDILVHPCVTSLDSAILTSSSIDAMDDSAFSGPYKFP
FTPPLESFNLCFYTSQVPVPPILGFYQMKEEEVQLRITINLKLHESVKNNFEFCEAHIPF
YNRGPITHLEYKTSFGQLEVFREKSLLIWIIGQKFPKSMEISLSGTVTFGAKSHEKQPFD
PICTGETAYLKLHFRILDYTLTGCYADQHSVQVFASGKPKISAHRKLISSDYYIWNSKAP
APVTYGSLLL

Sequence length

490

Interactions

View interactions

AP5M1 (adaptor related protein complex 5 subunit mu 1)