ATF7IP (activating transcription factor 7 interacting protein)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 55729 |
| Gene name | Activating transcription factor 7 interacting protein |
| Gene symbol | ATF7IP |
| Synonyms (NCBI Gene) |
AMATF-IPATF7IP1MCAFMCAF1p621
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| Chromosome | 12 |
| Chromosome location | 12p13.1 |
| Summary | ATF7IP is a multifunctional nuclear protein that associates with heterochromatin. It can act as a transcriptional coactivator or corepressor depending upon its binding partners (summary by Liu et al., 2009 [PubMed 19106100]).[supplied by OMIM, Nov 2010] |
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miRNA
miRNA information provided by mirtarbase database.
317
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
20
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q6VMQ6 | |||||||||||||||
| Protein name | Activating transcription factor 7-interacting protein 1 (ATF-interacting protein) (ATF-IP) (ATF7-interacting protein) (ATFa-associated modulator) (hAM) (MBD1-containing chromatin-associated factor 1) (P621) | |||||||||||||||
| Protein function | Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Required for HUSH-med | |||||||||||||||
| PDB | 2RPQ | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Detected at low levels in breast, lung and stomach; highly up-regulated in the corresponding cancerous tissues (at protein level). {ECO:0000269|PubMed:19106100}. | |||||||||||||||
| Sequence |
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| Sequence length | 1270 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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