ATF7IP (activating transcription factor 7 interacting protein)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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55729 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Activating transcription factor 7 interacting protein |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ATF7IP |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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AM, ATF-IP, ATF7IP1, MCAF, MCAF1, p621 |
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Chromosome
Chromosome number
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12 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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12p13.1 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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ATF7IP is a multifunctional nuclear protein that associates with heterochromatin. It can act as a transcriptional coactivator or corepressor depending upon its binding partners (summary by Liu et al., 2009 [PubMed 19106100]).[supplied by OMIM, Nov 2010] |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||
| UniProt ID | Q6VMQ6 | |||||||||||||||
| Protein name | Activating transcription factor 7-interacting protein 1 (ATF-interacting protein) (ATF-IP) (ATF7-interacting protein) (ATFa-associated modulator) (hAM) (MBD1-containing chromatin-associated factor 1) (P621) | |||||||||||||||
| Protein function | Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Required for HUSH-med | |||||||||||||||
| PDB | 2RPQ | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Detected at low levels in breast, lung and stomach; highly up-regulated in the corresponding cancerous tissues (at protein level). {ECO:0000269|PubMed:19106100}. | |||||||||||||||
| Sequence |
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| Sequence length | 1270 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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