Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	55729
Gene name Gene Name - the full gene name approved by the HGNC.	Activating transcription factor 7 interacting protein
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ATF7IP
Synonyms (NCBI Gene) Gene synonyms aliases	AM, ATF-IP, ATF7IP1, MCAF, MCAF1, p621
Chromosome Chromosome number	12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	12p13.1
Summary Summary of gene provided in NCBI Entrez Gene.	ATF7IP is a multifunctional nuclear protein that associates with heterochromatin. It can act as a transcriptional coactivator or corepressor depending upon its binding partners (summary by Liu et al., 2009 [PubMed 19106100]).[supplied by OMIM, Nov 2010]

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miRTarBase ID	miRNA	Experiments	Reference
MIRT046291	hsa-miR-23b-3p	CLASH	23622248
MIRT044675	hsa-miR-320a	CLASH	23622248
MIRT037643	hsa-miR-744-5p	CLASH	23622248
MIRT036221	hsa-miR-320b	CLASH	23622248
MIRT568427	hsa-miR-548c-3p	HITS-CLIP	19536157
MIRT711688	hsa-miR-548p	HITS-CLIP	19536157
MIRT711687	hsa-miR-21-5p	HITS-CLIP	19536157
MIRT711686	hsa-miR-590-5p	HITS-CLIP	19536157
MIRT711685	hsa-miR-186-3p	HITS-CLIP	19536157
MIRT711684	hsa-miR-3192-5p	HITS-CLIP	19536157
MIRT711683	hsa-miR-6878-5p	HITS-CLIP	19536157
MIRT711682	hsa-miR-6731-5p	HITS-CLIP	19536157
MIRT711681	hsa-miR-8085	HITS-CLIP	19536157
MIRT711680	hsa-miR-5579-3p	HITS-CLIP	19536157
MIRT711679	hsa-miR-33a-5p	HITS-CLIP	19536157
MIRT711678	hsa-miR-33b-5p	HITS-CLIP	19536157
MIRT711677	hsa-miR-30c-1-3p	HITS-CLIP	19536157
MIRT711676	hsa-miR-30c-2-3p	HITS-CLIP	19536157
MIRT711675	hsa-miR-6788-5p	HITS-CLIP	19536157
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT621076	hsa-miR-652-5p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT632058	hsa-miR-216a-5p	HITS-CLIP	23824327
MIRT632057	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT632056	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT632055	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT632054	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT632053	hsa-miR-3666	HITS-CLIP	23824327
MIRT632052	hsa-miR-4295	HITS-CLIP	23824327
MIRT632051	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT632050	hsa-miR-652-3p	HITS-CLIP	23824327
MIRT632049	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT632048	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT632047	hsa-miR-4485-5p	HITS-CLIP	23824327
MIRT632046	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT632045	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT632044	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT632043	hsa-miR-6722-5p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT621076	hsa-miR-652-5p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568427	hsa-miR-548c-3p	PAR-CLIP	20371350
MIRT568426	hsa-miR-144-3p	PAR-CLIP	20371350
MIRT568425	hsa-miR-16-1-3p	PAR-CLIP	20371350
MIRT568424	hsa-miR-4304	PAR-CLIP	20371350
MIRT568423	hsa-miR-198	PAR-CLIP	20371350
MIRT568422	hsa-miR-520a-5p	PAR-CLIP	20371350
MIRT568421	hsa-miR-525-5p	PAR-CLIP	20371350
MIRT568420	hsa-miR-3129-5p	PAR-CLIP	20371350
MIRT568419	hsa-miR-199b-3p	PAR-CLIP	20371350
MIRT568418	hsa-miR-199a-3p	PAR-CLIP	20371350
MIRT568417	hsa-miR-548ac	PAR-CLIP	20371350
MIRT568416	hsa-miR-548bb-3p	PAR-CLIP	20371350
MIRT568415	hsa-miR-548d-3p	PAR-CLIP	20371350
MIRT568414	hsa-miR-548h-3p	PAR-CLIP	20371350
MIRT568413	hsa-miR-548z	PAR-CLIP	20371350
MIRT568412	hsa-miR-548ae-3p	PAR-CLIP	20371350
MIRT568411	hsa-miR-548ah-3p	PAR-CLIP	20371350
MIRT568410	hsa-miR-548aj-3p	PAR-CLIP	20371350
MIRT568409	hsa-miR-548am-3p	PAR-CLIP	20371350
MIRT568408	hsa-miR-548aq-3p	PAR-CLIP	20371350
MIRT568407	hsa-miR-548j-3p	PAR-CLIP	20371350
MIRT568406	hsa-miR-548x-3p	PAR-CLIP	20371350
MIRT568405	hsa-miR-548as-3p	PAR-CLIP	20371350
MIRT568404	hsa-miR-548l	PAR-CLIP	20371350
MIRT568403	hsa-miR-3130-5p	PAR-CLIP	20371350
MIRT568402	hsa-miR-4482-5p	PAR-CLIP	20371350
MIRT568401	hsa-miR-1244	PAR-CLIP	20371350
MIRT568400	hsa-miR-205-3p	PAR-CLIP	20371350
MIRT568399	hsa-miR-3973	PAR-CLIP	20371350
MIRT568398	hsa-miR-520g-3p	PAR-CLIP	20371350
MIRT568397	hsa-miR-520h	PAR-CLIP	20371350
MIRT568396	hsa-miR-3155a	PAR-CLIP	20371350
MIRT568395	hsa-miR-3155b	PAR-CLIP	20371350
MIRT568394	hsa-miR-484	PAR-CLIP	20371350
MIRT568393	hsa-miR-607	PAR-CLIP	20371350
MIRT491012	hsa-miR-25-3p	PAR-CLIP	23592263
MIRT491011	hsa-miR-32-5p	PAR-CLIP	23592263
MIRT491010	hsa-miR-363-3p	PAR-CLIP	23592263
MIRT491009	hsa-miR-367-3p	PAR-CLIP	23592263
MIRT491008	hsa-miR-92a-3p	PAR-CLIP	23592263
MIRT491007	hsa-miR-92b-3p	PAR-CLIP	23592263
MIRT491006	hsa-miR-3145-3p	PAR-CLIP	23592263
MIRT491005	hsa-miR-548aw	PAR-CLIP	23592263
MIRT491004	hsa-miR-518a-5p	PAR-CLIP	23592263
MIRT491003	hsa-miR-527	PAR-CLIP	23592263
MIRT491002	hsa-miR-1303	PAR-CLIP	23592263
MIRT491001	hsa-miR-599	PAR-CLIP	23592263
MIRT568427	hsa-miR-548c-3p	HITS-CLIP	19536157
MIRT711688	hsa-miR-548p	HITS-CLIP	19536157
MIRT711687	hsa-miR-21-5p	HITS-CLIP	19536157
MIRT711686	hsa-miR-590-5p	HITS-CLIP	19536157
MIRT711685	hsa-miR-186-3p	HITS-CLIP	19536157
MIRT711684	hsa-miR-3192-5p	HITS-CLIP	19536157
MIRT711683	hsa-miR-6878-5p	HITS-CLIP	19536157
MIRT711682	hsa-miR-6731-5p	HITS-CLIP	19536157
MIRT711681	hsa-miR-8085	HITS-CLIP	19536157
MIRT711680	hsa-miR-5579-3p	HITS-CLIP	19536157
MIRT711679	hsa-miR-33a-5p	HITS-CLIP	19536157
MIRT711678	hsa-miR-33b-5p	HITS-CLIP	19536157
MIRT711677	hsa-miR-30c-1-3p	HITS-CLIP	19536157
MIRT711676	hsa-miR-30c-2-3p	HITS-CLIP	19536157
MIRT711675	hsa-miR-6788-5p	HITS-CLIP	19536157
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT621076	hsa-miR-652-5p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT632058	hsa-miR-216a-5p	HITS-CLIP	23824327
MIRT632057	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT632056	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT632055	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT632054	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT632053	hsa-miR-3666	HITS-CLIP	23824327
MIRT632052	hsa-miR-4295	HITS-CLIP	23824327
MIRT632051	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT632050	hsa-miR-652-3p	HITS-CLIP	23824327
MIRT632049	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT632048	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT632047	hsa-miR-4485-5p	HITS-CLIP	23824327
MIRT632046	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT632045	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT632044	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT632043	hsa-miR-6722-5p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT621076	hsa-miR-652-5p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT616018	hsa-miR-8485	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568405	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT613304	hsa-miR-1323	HITS-CLIP	23824327
MIRT613303	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT568427	hsa-miR-548c-3p	PAR-CLIP	20371350
MIRT568426	hsa-miR-144-3p	PAR-CLIP	20371350
MIRT568425	hsa-miR-16-1-3p	PAR-CLIP	20371350
MIRT568424	hsa-miR-4304	PAR-CLIP	20371350
MIRT568423	hsa-miR-198	PAR-CLIP	20371350
MIRT568422	hsa-miR-520a-5p	PAR-CLIP	20371350
MIRT568421	hsa-miR-525-5p	PAR-CLIP	20371350
MIRT568420	hsa-miR-3129-5p	PAR-CLIP	20371350
MIRT568419	hsa-miR-199b-3p	PAR-CLIP	20371350
MIRT568418	hsa-miR-199a-3p	PAR-CLIP	20371350
MIRT568417	hsa-miR-548ac	PAR-CLIP	20371350
MIRT568416	hsa-miR-548bb-3p	PAR-CLIP	20371350
MIRT568415	hsa-miR-548d-3p	PAR-CLIP	20371350
MIRT568414	hsa-miR-548h-3p	PAR-CLIP	20371350
MIRT568413	hsa-miR-548z	PAR-CLIP	20371350
MIRT568412	hsa-miR-548ae-3p	PAR-CLIP	20371350
MIRT568411	hsa-miR-548ah-3p	PAR-CLIP	20371350
MIRT568410	hsa-miR-548aj-3p	PAR-CLIP	20371350
MIRT568409	hsa-miR-548am-3p	PAR-CLIP	20371350
MIRT568408	hsa-miR-548aq-3p	PAR-CLIP	20371350
MIRT568407	hsa-miR-548j-3p	PAR-CLIP	20371350
MIRT568406	hsa-miR-548x-3p	PAR-CLIP	20371350
MIRT568405	hsa-miR-548as-3p	PAR-CLIP	20371350
MIRT568404	hsa-miR-548l	PAR-CLIP	20371350
MIRT568403	hsa-miR-3130-5p	PAR-CLIP	20371350
MIRT568402	hsa-miR-4482-5p	PAR-CLIP	20371350
MIRT568401	hsa-miR-1244	PAR-CLIP	20371350
MIRT568400	hsa-miR-205-3p	PAR-CLIP	20371350
MIRT568399	hsa-miR-3973	PAR-CLIP	20371350
MIRT568398	hsa-miR-520g-3p	PAR-CLIP	20371350
MIRT568397	hsa-miR-520h	PAR-CLIP	20371350
MIRT568396	hsa-miR-3155a	PAR-CLIP	20371350
MIRT568395	hsa-miR-3155b	PAR-CLIP	20371350
MIRT568394	hsa-miR-484	PAR-CLIP	20371350
MIRT568393	hsa-miR-607	PAR-CLIP	20371350
MIRT491012	hsa-miR-25-3p	PAR-CLIP	23592263
MIRT491011	hsa-miR-32-5p	PAR-CLIP	23592263
MIRT491010	hsa-miR-363-3p	PAR-CLIP	23592263
MIRT491009	hsa-miR-367-3p	PAR-CLIP	23592263
MIRT491008	hsa-miR-92a-3p	PAR-CLIP	23592263
MIRT491007	hsa-miR-92b-3p	PAR-CLIP	23592263
MIRT491006	hsa-miR-3145-3p	PAR-CLIP	23592263
MIRT491005	hsa-miR-548aw	PAR-CLIP	23592263
MIRT491004	hsa-miR-518a-5p	PAR-CLIP	23592263
MIRT491003	hsa-miR-527	PAR-CLIP	23592263
MIRT491002	hsa-miR-1303	PAR-CLIP	23592263
MIRT491001	hsa-miR-599	PAR-CLIP	23592263
MIRT804724	hsa-miR-142-3p	CLIP-seq
MIRT804725	hsa-miR-1587	CLIP-seq
MIRT804726	hsa-miR-1914	CLIP-seq
MIRT804727	hsa-miR-3074-5p	CLIP-seq
MIRT804728	hsa-miR-3124-3p	CLIP-seq
MIRT804729	hsa-miR-340	CLIP-seq
MIRT804730	hsa-miR-3977	CLIP-seq
MIRT804731	hsa-miR-4265	CLIP-seq
MIRT804732	hsa-miR-4280	CLIP-seq
MIRT804733	hsa-miR-4296	CLIP-seq
MIRT804734	hsa-miR-4322	CLIP-seq
MIRT804735	hsa-miR-4417	CLIP-seq
MIRT804736	hsa-miR-4492	CLIP-seq
MIRT804737	hsa-miR-4498	CLIP-seq
MIRT804738	hsa-miR-4656	CLIP-seq
MIRT804739	hsa-miR-4675	CLIP-seq
MIRT804740	hsa-miR-4682	CLIP-seq
MIRT804741	hsa-miR-4741	CLIP-seq
MIRT804742	hsa-miR-501-5p	CLIP-seq
MIRT804743	hsa-miR-762	CLIP-seq
MIRT804744	hsa-miR-935	CLIP-seq
MIRT804724	hsa-miR-142-3p	CLIP-seq
MIRT804729	hsa-miR-340	CLIP-seq
MIRT1937566	hsa-miR-3938	CLIP-seq
MIRT1937567	hsa-miR-3941	CLIP-seq
MIRT804730	hsa-miR-3977	CLIP-seq
MIRT804732	hsa-miR-4280	CLIP-seq
MIRT1937568	hsa-miR-4643	CLIP-seq
MIRT1937569	hsa-miR-466	CLIP-seq
MIRT1937570	hsa-miR-4672	CLIP-seq
MIRT1937571	hsa-miR-4789-3p	CLIP-seq
MIRT1937572	hsa-miR-4789-5p	CLIP-seq
MIRT1937573	hsa-miR-548g	CLIP-seq
MIRT804744	hsa-miR-935	CLIP-seq
MIRT804725	hsa-miR-1587	CLIP-seq
MIRT2177185	hsa-miR-3145-5p	CLIP-seq
MIRT2177186	hsa-miR-3148	CLIP-seq
MIRT2177187	hsa-miR-3591-3p	CLIP-seq
MIRT2177188	hsa-miR-3658	CLIP-seq
MIRT1937566	hsa-miR-3938	CLIP-seq
MIRT1937567	hsa-miR-3941	CLIP-seq
MIRT804731	hsa-miR-4265	CLIP-seq
MIRT804733	hsa-miR-4296	CLIP-seq
MIRT804734	hsa-miR-4322	CLIP-seq
MIRT804735	hsa-miR-4417	CLIP-seq
MIRT2177189	hsa-miR-4422	CLIP-seq
MIRT804736	hsa-miR-4492	CLIP-seq
MIRT804737	hsa-miR-4498	CLIP-seq
MIRT1937568	hsa-miR-4643	CLIP-seq
MIRT804738	hsa-miR-4656	CLIP-seq
MIRT1937569	hsa-miR-466	CLIP-seq
MIRT1937570	hsa-miR-4672	CLIP-seq
MIRT804739	hsa-miR-4675	CLIP-seq
MIRT804740	hsa-miR-4682	CLIP-seq
MIRT804741	hsa-miR-4741	CLIP-seq
MIRT1937571	hsa-miR-4789-3p	CLIP-seq
MIRT2177190	hsa-miR-513a-3p	CLIP-seq
MIRT1937573	hsa-miR-548g	CLIP-seq
MIRT2177191	hsa-miR-548o	CLIP-seq
MIRT2177192	hsa-miR-580	CLIP-seq
MIRT804743	hsa-miR-762	CLIP-seq

Show/Hide all(19)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IEA
GO:0003714	Function	Transcription corepressor activity	IEA
GO:0005515	Function	Protein binding	IPI	12665582, 12812986, 26275350, 27732843
GO:0005634	Component	Nucleus	IDA	12665582
GO:0005634	Component	Nucleus	IMP	27732843
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005667	Component	Transcription regulator complex	IEA
GO:0005829	Component	Cytosol	IDA
GO:0006306	Process	DNA methylation	IDA	12665582
GO:0016032	Process	Viral process	IEA
GO:0016604	Component	Nuclear body	IDA
GO:0016887	Function	ATPase activity	IEA
GO:0031647	Process	Regulation of protein stability	IMP	27732843
GO:0045892	Process	Negative regulation of transcription, DNA-templated	IDA	12665582
GO:0045893	Process	Positive regulation of transcription, DNA-templated	IDA	12665582
GO:0045898	Process	Regulation of RNA polymerase II transcription preinitiation complex assembly	IDA	12665582
GO:0050821	Process	Protein stabilization	IMP	27732843
GO:0090309	Process	Positive regulation of DNA methylation-dependent heterochromatin assembly	IMP	27732843

MIM	HGNC	e!Ensembl
613644	20092	ENSG00000171681

Protein

UniProt ID

Q6VMQ6

Protein name

Activating transcription factor 7-interacting protein 1 (ATF-interacting protein) (ATF-IP) (ATF7-interacting protein) (ATFa-associated modulator) (hAM) (MBD1-containing chromatin-associated factor 1) (P621)

Protein function

Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Required for HUSH-med

PDB

2RPQ

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF16788	ATF7IP_BD	564 → 779	ATF-interacting protein binding domain	Family
PF16794	fn3_4	1159 → 1260	Fibronectin-III type domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Detected at low levels in breast, lung and stomach; highly up-regulated in the corresponding cancerous tissues (at protein level). {ECO:0000269|PubMed:19106100}.

Sequence

MDSLEEPQKKVFKARKTMRVSDRQQLEAVYKVKEELLKTDVKLLNGNHENGDLDPTSPLE
NMDYIKDKEEVNGIEEICFDPEGSKAEWKETPCILSVNVKNKQDDDLNCEPLSPHNITPE
PVSKLPAEPVSGDPAPGDLDAGDPASGVLASGDSTSGDPTSSEPSSSDAASGDATSGDAP
SGDVSPGDATSGDATADDLSSGDPTSSDPIPGEPVPVEPISGDCAADDIASSEITSVDLA
SGAPASTDPASDDLASGDLSSSELASDDLATGELASDELTSESTFDRTFEPKSVPVCEPV
PEIDNIEPSSNKDDDFLEKNGADEKLEQIQSKDSLDEKNKADNNIDANEETLETDDTTIC
SDRPPENEKKVEEDIITELALGEDAISSSMEIDQGEKNEDETSADLVETINENVIEDNKS
ENILENTDSMETDEIIPILEKLAPSEDELTCFSKTSLLPIDETNPDLEEKMESSFGSPSK
QESSESLPKEAFLVLSDEEDISGEKDESEVISQNETCSPAEVESNEKDNKPEEEEQVIHE
DDERPSEKNEFSRRKRSKSEDMDNVQSKRRRYMEEEYEAEFQVKITAKGDINQKLQKVIQ
WLLEEKLCALQCAVFDKTLAELKTRVEKIECNKRHKTVLTELQAKIARLTKRFEAAKEDL
KKRHEHPPNPPVSPGKTVNDVNSNNNMSYRNAGTVRQMLESKRNVSESAPPSFQTPVNTV
SSTNLVTPPAVVSSQPKLQTPVTSGSLTATSVLPAPNTATVVATTQVPSGNPQPTISLQP
LPVILHVPVAVSSQPQLLQSHPGTLVTNQPSGNVEFISVQSPPTVSGLTKNPVSLPSLPN
PTKPNNVPSVPSPSIQRNPTASAAPLGTTLAVQAVPTAHSIVQATRTSLPTVGPSGLYSP
STNRGPIQMKIPISAFSTSSAAEQNSNTTPRIENQTNKTIDASVSKKAADSTSQCGKATG
SDSSGVIDLTMDDEESGASQDPKKLNHTPVSTMSSSQPVSRPLQPIQPAPPLQPSGVPTS
GPSQTTIHLLPTAPTTVNVTHRPVTQVTTRLPVPRAPANHQVVYTTLPAPPAQAPLRGTV
MQAPAVRQVNPQNSVTVRVPQTTTYVVNNGLTLGSTGPQLTVHHRPPQVHTEPPRPVHPA
PLPEAPQPQRLPPEAASTSLPQKPHLKLARVQSQNGIVLSWSVLEVDRSCATVDSYHLYA
YHEEPSATVPSQWKKIGEVKALPLPMACTLTQFVSGSKYYFAVRAKDIYGRFGPFCDPQS
TDVISSTQSS

Sequence length

1270

Interactions

View interactions

	Reactome
			PKMTs methylate histone lysines

Show/Hide Causal Diseases (3)

Disease term	Disease name	dbSNP ID	References
Causal
Neoplasm	Neoplasms, Germ Cell and Embryonal, Neoplasms, Embryonal and Mixed	rs137854562, rs137854565, rs137854568, rs137854574, rs121434220, rs121909218, rs121909222, rs587776667, rs606231169, rs587776701, rs121913388, rs137852578, rs137852216, rs121912651, rs28934575 View all (247 more)	20543847
Lymphoblastic leukemia	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	rs387906351, rs104894562, rs398122513, rs398122840, rs1057524466, rs1064796115, rs1064795660, rs1064793129, rs1064796227, rs1567887558, rs1161194345, rs1597558200, rs1406320425, rs1597566470, rs1597566699 View all (13 more)	24413735
Schizophrenia	Schizophrenia	rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346 View all (12 more)	31374203

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Testicular Germ Cell Tumor	Testicular Germ Cell Tumor			GWAS

Show/Hide Text Mining Associations (22)

Disease Name	Relationship Type	References
Associations from Text Mining
Adenocarcinoma of Lung	Associate	31959344
Anodontia	Associate	35175239
Breast Neoplasms	Associate	29061142, 37685980
Cementoma	Associate	37995913
Colorectal Neoplasms	Associate	35175239
Esophageal Squamous Cell Carcinoma	Associate	36966136
Glucocorticoid Receptor Deficiency	Stimulate	29133777
Hematologic Neoplasms	Associate	33794925
Huntington Disease	Associate	26148071
Inflammation	Associate	36981614
Leukemia	Associate	29061142, 34982829
Leukemia Biphenotypic Acute	Associate	24628626
Microsatellite Instability	Associate	35175239
Neoplasms	Associate	19106100, 32012497, 37685980
Neoplasms	Inhibit	24413735
Neoplasms Germ Cell and Embryonal	Associate	20543847, 28804972
Philadelphia Chromosome	Associate	24628626, 29133777
Precursor Cell Lymphoblastic Leukemia Lymphoma	Associate	29133777
Precursor T Cell Lymphoblastic Leukemia Lymphoma	Associate	24628626
Testicular Germ Cell Tumor	Associate	21551455
Testicular Neoplasms	Associate	21564132
Tetra amelia with ectodermal dysplasia and lacrimal duct abnormalities	Associate	34982829

ATF7IP (activating transcription factor 7 interacting protein)