N4BP2 (NEDD4 binding protein 2)
| Gene | |
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
55728 |
|
Gene name
Gene Name - the full gene name approved by the HGNC.
|
NEDD4 binding protein 2 |
|
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
N4BP2 |
|
Synonyms (NCBI Gene)
Gene synonyms aliases
|
B3BP |
|
Chromosome
Chromosome number
|
4 |
|
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
4p14 |
|
Summary
Summary of gene provided in NCBI Entrez Gene.
|
This gene encodes a protein containing a polynucleotide kinase domain (PNK) near the N-terminal region, and a Small MutS Related (Smr) domain near the C-terminal region. The encoded protein can bind to both B-cell leukemia/lymphoma 3 (BCL-3) and neural pr |
|
miRNA
miRNA information provided by mirtarbase database.
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
|
Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|||||||
|
|||||||
| Protein | |||||||||||||||||||||
| UniProt ID | Q86UW6 | ||||||||||||||||||||
| Protein name | NEDD4-binding protein 2 (N4BP2) (EC 3.-.-.-) (BCL-3-binding protein) | ||||||||||||||||||||
| Protein function | Has 5'-polynucleotide kinase and nicking endonuclease activity. May play a role in DNA repair or recombination. | ||||||||||||||||||||
| PDB | 2D9I , 2VKC , 3BHB , 3FAU | ||||||||||||||||||||
| Family and domains |
Pfam
|
||||||||||||||||||||
| Sequence |
|
||||||||||||||||||||
| Sequence length | 1770 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
|
Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
|
|||||||||||||||||||||
|
|||||||||||||||||||||
|
|||||||||||||||||||||