PACS1 (phosphofurin acidic cluster sorting protein 1)

Gene

• Entrez ID: 55690
• Gene name: Phosphofurin acidic cluster sorting protein 1
• Gene symbol: PACS1
• Synonyms (NCBI Gene): MRD17, SHMS
• Chromosome: 11
• Chromosome location: 11q13.1-q13.2
• Summary: This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of fur

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs1064795125	G>C	Likely-pathogenic	Genic downstream transcript variant, splice donor variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT044795	hsa-miR-320a	CLASH	23622248
MIRT043109	hsa-miR-324-5p	CLASH	23622248
MIRT620231	hsa-miR-8485	HITS-CLIP	23824327
MIRT620230	hsa-miR-9-5p	HITS-CLIP	23824327
MIRT620229	hsa-miR-7-5p	HITS-CLIP	23824327
MIRT620228	hsa-miR-6077	HITS-CLIP	23824327
MIRT620227	hsa-miR-6079	HITS-CLIP	23824327
MIRT626356	hsa-miR-1306-5p	HITS-CLIP	23824327
MIRT626355	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT626354	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT626353	hsa-miR-4324	HITS-CLIP	23824327
MIRT626352	hsa-miR-544b	HITS-CLIP	23824327
MIRT631776	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT626351	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT626350	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT631775	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT631774	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT626349	hsa-miR-4682	HITS-CLIP	23824327
MIRT626347	hsa-miR-4284	HITS-CLIP	23824327
MIRT626346	hsa-miR-1200	HITS-CLIP	23824327
MIRT626356	hsa-miR-1306-5p	HITS-CLIP	23824327
MIRT626355	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT626354	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT626353	hsa-miR-4324	HITS-CLIP	23824327
MIRT626352	hsa-miR-544b	HITS-CLIP	23824327
MIRT626351	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT626350	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT626349	hsa-miR-4682	HITS-CLIP	23824327
MIRT626348	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT626347	hsa-miR-4284	HITS-CLIP	23824327
MIRT626346	hsa-miR-1200	HITS-CLIP	23824327
MIRT620231	hsa-miR-8485	HITS-CLIP	23824327
MIRT620230	hsa-miR-9-5p	HITS-CLIP	23824327
MIRT620229	hsa-miR-7-5p	HITS-CLIP	23824327
MIRT620228	hsa-miR-6077	HITS-CLIP	23824327
MIRT620227	hsa-miR-6079	HITS-CLIP	23824327
MIRT530082	hsa-miR-4461	PAR-CLIP	22012620
MIRT530081	hsa-miR-3614-5p	PAR-CLIP	22012620
MIRT530080	hsa-miR-610	PAR-CLIP	22012620
MIRT530079	hsa-miR-3145-3p	PAR-CLIP	22012620
MIRT530078	hsa-miR-450b-3p	PAR-CLIP	22012620
MIRT530077	hsa-miR-769-3p	PAR-CLIP	22012620
MIRT530076	hsa-miR-6728-5p	PAR-CLIP	22012620
MIRT530075	hsa-miR-5089-5p	PAR-CLIP	22012620
MIRT530074	hsa-miR-599	PAR-CLIP	22012620
MIRT530073	hsa-miR-6513-5p	PAR-CLIP	22012620
MIRT446799	hsa-miR-3662	PAR-CLIP	22100165
MIRT446798	hsa-miR-935	PAR-CLIP	22100165
MIRT446797	hsa-miR-4711-5p	PAR-CLIP	22100165
MIRT446796	hsa-miR-431-5p	PAR-CLIP	22100165
MIRT446795	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT446794	hsa-miR-6869-5p	PAR-CLIP	22100165
MIRT446799	hsa-miR-3662	PAR-CLIP	22100165
MIRT446798	hsa-miR-935	PAR-CLIP	22100165
MIRT446797	hsa-miR-4711-5p	PAR-CLIP	22100165
MIRT446796	hsa-miR-431-5p	PAR-CLIP	22100165
MIRT446795	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT446794	hsa-miR-6869-5p	PAR-CLIP	22100165
MIRT440058	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440058	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT626352	hsa-miR-544b	PAR-CLIP	26701625
MIRT620231	hsa-miR-8485	HITS-CLIP	23824327
MIRT620230	hsa-miR-9-5p	HITS-CLIP	23824327
MIRT620229	hsa-miR-7-5p	HITS-CLIP	23824327
MIRT620228	hsa-miR-6077	HITS-CLIP	23824327
MIRT620227	hsa-miR-6079	HITS-CLIP	23824327
MIRT626356	hsa-miR-1306-5p	HITS-CLIP	23824327
MIRT626355	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT626354	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT626353	hsa-miR-4324	HITS-CLIP	23824327
MIRT626352	hsa-miR-544b	HITS-CLIP	23824327
MIRT631776	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT626351	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT626350	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT631775	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT631774	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT626349	hsa-miR-4682	HITS-CLIP	23824327
MIRT626347	hsa-miR-4284	HITS-CLIP	23824327
MIRT626346	hsa-miR-1200	HITS-CLIP	23824327
MIRT626356	hsa-miR-1306-5p	HITS-CLIP	23824327
MIRT626355	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT626354	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT626353	hsa-miR-4324	HITS-CLIP	23824327
MIRT626352	hsa-miR-544b	HITS-CLIP	23824327
MIRT626351	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT626350	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT626349	hsa-miR-4682	HITS-CLIP	23824327
MIRT626348	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT626347	hsa-miR-4284	HITS-CLIP	23824327
MIRT626346	hsa-miR-1200	HITS-CLIP	23824327
MIRT620231	hsa-miR-8485	HITS-CLIP	23824327
MIRT620230	hsa-miR-9-5p	HITS-CLIP	23824327
MIRT620229	hsa-miR-7-5p	HITS-CLIP	23824327
MIRT620228	hsa-miR-6077	HITS-CLIP	23824327
MIRT620227	hsa-miR-6079	HITS-CLIP	23824327
MIRT530082	hsa-miR-4461	PAR-CLIP	22012620
MIRT530081	hsa-miR-3614-5p	PAR-CLIP	22012620
MIRT530080	hsa-miR-610	PAR-CLIP	22012620
MIRT530079	hsa-miR-3145-3p	PAR-CLIP	22012620
MIRT530078	hsa-miR-450b-3p	PAR-CLIP	22012620
MIRT530077	hsa-miR-769-3p	PAR-CLIP	22012620
MIRT530076	hsa-miR-6728-5p	PAR-CLIP	22012620
MIRT530075	hsa-miR-5089-5p	PAR-CLIP	22012620
MIRT530074	hsa-miR-599	PAR-CLIP	22012620
MIRT530073	hsa-miR-6513-5p	PAR-CLIP	22012620
MIRT446799	hsa-miR-3662	PAR-CLIP	22100165
MIRT446798	hsa-miR-935	PAR-CLIP	22100165
MIRT446797	hsa-miR-4711-5p	PAR-CLIP	22100165
MIRT446796	hsa-miR-431-5p	PAR-CLIP	22100165
MIRT446795	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT446794	hsa-miR-6869-5p	PAR-CLIP	22100165
MIRT446799	hsa-miR-3662	PAR-CLIP	22100165
MIRT446798	hsa-miR-935	PAR-CLIP	22100165
MIRT446797	hsa-miR-4711-5p	PAR-CLIP	22100165
MIRT446796	hsa-miR-431-5p	PAR-CLIP	22100165
MIRT446795	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT446794	hsa-miR-6869-5p	PAR-CLIP	22100165
MIRT1209773	hsa-miR-1184	CLIP-seq
MIRT1209774	hsa-miR-1197	CLIP-seq
MIRT1209775	hsa-miR-1205	CLIP-seq
MIRT1209776	hsa-miR-1252	CLIP-seq
MIRT1209777	hsa-miR-1254	CLIP-seq
MIRT1209778	hsa-miR-1262	CLIP-seq
MIRT1209779	hsa-miR-1285	CLIP-seq
MIRT1209780	hsa-miR-1287	CLIP-seq
MIRT1209781	hsa-miR-1293	CLIP-seq
MIRT1209782	hsa-miR-140-3p	CLIP-seq
MIRT1209783	hsa-miR-143	CLIP-seq
MIRT1209784	hsa-miR-146a	CLIP-seq
MIRT1209785	hsa-miR-146b-5p	CLIP-seq
MIRT1209786	hsa-miR-1538	CLIP-seq
MIRT1209787	hsa-miR-1587	CLIP-seq
MIRT1209788	hsa-miR-1827	CLIP-seq
MIRT1209789	hsa-miR-1909	CLIP-seq
MIRT1209790	hsa-miR-1910	CLIP-seq
MIRT1209791	hsa-miR-193a-5p	CLIP-seq
MIRT1209792	hsa-miR-19a	CLIP-seq
MIRT1209793	hsa-miR-19b	CLIP-seq
MIRT1209794	hsa-miR-2278	CLIP-seq
MIRT1209795	hsa-miR-2392	CLIP-seq
MIRT1209796	hsa-miR-2467-3p	CLIP-seq
MIRT1209797	hsa-miR-296-5p	CLIP-seq
MIRT1209798	hsa-miR-3064-5p	CLIP-seq
MIRT1209799	hsa-miR-3116	CLIP-seq
MIRT1209800	hsa-miR-3133	CLIP-seq
MIRT1209801	hsa-miR-3135b	CLIP-seq
MIRT1209802	hsa-miR-3153	CLIP-seq
MIRT1209803	hsa-miR-3154	CLIP-seq
MIRT1209804	hsa-miR-3158-5p	CLIP-seq
MIRT1209805	hsa-miR-3173-3p	CLIP-seq
MIRT1209806	hsa-miR-3175	CLIP-seq
MIRT1209807	hsa-miR-3177-3p	CLIP-seq
MIRT1209808	hsa-miR-3179	CLIP-seq
MIRT1209809	hsa-miR-3184	CLIP-seq
MIRT1209810	hsa-miR-3187-5p	CLIP-seq
MIRT1209811	hsa-miR-3189-3p	CLIP-seq
MIRT1209812	hsa-miR-3190	CLIP-seq
MIRT1209813	hsa-miR-3192	CLIP-seq
MIRT1209814	hsa-miR-3202	CLIP-seq
MIRT1209815	hsa-miR-342-5p	CLIP-seq
MIRT1209816	hsa-miR-3605-5p	CLIP-seq
MIRT1209817	hsa-miR-3612	CLIP-seq
MIRT1209818	hsa-miR-3650	CLIP-seq
MIRT1209819	hsa-miR-3652	CLIP-seq
MIRT1209820	hsa-miR-3657	CLIP-seq
MIRT1209821	hsa-miR-3664-3p	CLIP-seq
MIRT1209822	hsa-miR-3689a-3p	CLIP-seq
MIRT1209823	hsa-miR-3689c	CLIP-seq
MIRT1209824	hsa-miR-370	CLIP-seq
MIRT1209825	hsa-miR-3714	CLIP-seq
MIRT1209826	hsa-miR-378g	CLIP-seq
MIRT1209827	hsa-miR-3909	CLIP-seq
MIRT1209828	hsa-miR-3936	CLIP-seq
MIRT1209829	hsa-miR-3944-5p	CLIP-seq
MIRT1209830	hsa-miR-423-5p	CLIP-seq
MIRT1209831	hsa-miR-4251	CLIP-seq
MIRT1209832	hsa-miR-4254	CLIP-seq
MIRT1209833	hsa-miR-4264	CLIP-seq
MIRT1209834	hsa-miR-4271	CLIP-seq
MIRT1209835	hsa-miR-4417	CLIP-seq
MIRT1209836	hsa-miR-4419a	CLIP-seq
MIRT1209837	hsa-miR-4428	CLIP-seq
MIRT1209838	hsa-miR-4430	CLIP-seq
MIRT1209839	hsa-miR-4434	CLIP-seq
MIRT1209840	hsa-miR-4436a	CLIP-seq
MIRT1209841	hsa-miR-4443	CLIP-seq
MIRT1209842	hsa-miR-4447	CLIP-seq
MIRT1209843	hsa-miR-4457	CLIP-seq
MIRT1209844	hsa-miR-4459	CLIP-seq
MIRT1209845	hsa-miR-4462	CLIP-seq
MIRT1209846	hsa-miR-4463	CLIP-seq
MIRT1209847	hsa-miR-4472	CLIP-seq
MIRT1209848	hsa-miR-4483	CLIP-seq
MIRT1209849	hsa-miR-4486	CLIP-seq
MIRT1209850	hsa-miR-4492	CLIP-seq
MIRT1209851	hsa-miR-4498	CLIP-seq
MIRT1209852	hsa-miR-4505	CLIP-seq
MIRT1209853	hsa-miR-4510	CLIP-seq
MIRT1209854	hsa-miR-4514	CLIP-seq
MIRT1209855	hsa-miR-4516	CLIP-seq
MIRT1209856	hsa-miR-4521	CLIP-seq
MIRT1209857	hsa-miR-4533	CLIP-seq
MIRT1209858	hsa-miR-455-3p	CLIP-seq
MIRT1209859	hsa-miR-4651	CLIP-seq
MIRT1209860	hsa-miR-4652-5p	CLIP-seq
MIRT1209861	hsa-miR-4656	CLIP-seq
MIRT1209862	hsa-miR-4664-5p	CLIP-seq
MIRT1209863	hsa-miR-4668-5p	CLIP-seq
MIRT1209864	hsa-miR-4669	CLIP-seq
MIRT1209865	hsa-miR-4675	CLIP-seq
MIRT1209866	hsa-miR-4685-5p	CLIP-seq
MIRT1209867	hsa-miR-4692	CLIP-seq
MIRT1209868	hsa-miR-4701-3p	CLIP-seq
MIRT1209869	hsa-miR-4710	CLIP-seq
MIRT1209870	hsa-miR-4716-3p	CLIP-seq
MIRT1209871	hsa-miR-4717-3p	CLIP-seq
MIRT1209872	hsa-miR-4722-5p	CLIP-seq
MIRT1209873	hsa-miR-4723-5p	CLIP-seq
MIRT1209874	hsa-miR-4725-3p	CLIP-seq
MIRT1209875	hsa-miR-4728-5p	CLIP-seq
MIRT1209876	hsa-miR-4731-5p	CLIP-seq
MIRT1209877	hsa-miR-4741	CLIP-seq
MIRT1209878	hsa-miR-4745-3p	CLIP-seq
MIRT1209879	hsa-miR-4747-5p	CLIP-seq
MIRT1209880	hsa-miR-4749-3p	CLIP-seq
MIRT1209881	hsa-miR-4755-3p	CLIP-seq
MIRT1209882	hsa-miR-4770	CLIP-seq
MIRT1209883	hsa-miR-4773	CLIP-seq
MIRT1209884	hsa-miR-4779	CLIP-seq
MIRT1209885	hsa-miR-4786-3p	CLIP-seq
MIRT1209886	hsa-miR-483-3p	CLIP-seq
MIRT1209887	hsa-miR-490-3p	CLIP-seq
MIRT1209888	hsa-miR-510	CLIP-seq
MIRT1209889	hsa-miR-517a	CLIP-seq
MIRT1209890	hsa-miR-517b	CLIP-seq
MIRT1209891	hsa-miR-517c	CLIP-seq
MIRT1209892	hsa-miR-518a-5p	CLIP-seq
MIRT1209893	hsa-miR-527	CLIP-seq
MIRT1209894	hsa-miR-541	CLIP-seq
MIRT1209895	hsa-miR-548a-3p	CLIP-seq
MIRT1209896	hsa-miR-548aa	CLIP-seq
MIRT1209897	hsa-miR-548ae	CLIP-seq
MIRT1209898	hsa-miR-548aj	CLIP-seq
MIRT1209899	hsa-miR-548am	CLIP-seq
MIRT1209900	hsa-miR-548an	CLIP-seq
MIRT1209901	hsa-miR-548b-3p	CLIP-seq
MIRT1209902	hsa-miR-548e	CLIP-seq
MIRT1209903	hsa-miR-548f	CLIP-seq
MIRT1209904	hsa-miR-548q	CLIP-seq
MIRT1209905	hsa-miR-548x	CLIP-seq
MIRT1209906	hsa-miR-589	CLIP-seq
MIRT1209907	hsa-miR-592	CLIP-seq
MIRT1209908	hsa-miR-596	CLIP-seq
MIRT1209909	hsa-miR-597	CLIP-seq
MIRT1209910	hsa-miR-608	CLIP-seq
MIRT1209911	hsa-miR-612	CLIP-seq
MIRT1209912	hsa-miR-625	CLIP-seq
MIRT1209913	hsa-miR-635	CLIP-seq
MIRT1209914	hsa-miR-637	CLIP-seq
MIRT1209915	hsa-miR-650	CLIP-seq
MIRT1209916	hsa-miR-654-5p	CLIP-seq
MIRT1209917	hsa-miR-671-5p	CLIP-seq
MIRT1209918	hsa-miR-676	CLIP-seq
MIRT1209919	hsa-miR-759	CLIP-seq
MIRT1209920	hsa-miR-762	CLIP-seq
MIRT1209921	hsa-miR-765	CLIP-seq
MIRT1209922	hsa-miR-873	CLIP-seq
MIRT1209923	hsa-miR-922	CLIP-seq
MIRT1209924	hsa-miR-940	CLIP-seq
MIRT1209776	hsa-miR-1252	CLIP-seq
MIRT1209778	hsa-miR-1262	CLIP-seq
MIRT2060161	hsa-miR-1275	CLIP-seq
MIRT1209780	hsa-miR-1287	CLIP-seq
MIRT1209781	hsa-miR-1293	CLIP-seq
MIRT2060162	hsa-miR-1321	CLIP-seq
MIRT2060163	hsa-miR-1324	CLIP-seq
MIRT1209782	hsa-miR-140-3p	CLIP-seq
MIRT1209783	hsa-miR-143	CLIP-seq
MIRT2060164	hsa-miR-148a	CLIP-seq
MIRT2060165	hsa-miR-148b	CLIP-seq
MIRT2060166	hsa-miR-152	CLIP-seq
MIRT2060167	hsa-miR-1825	CLIP-seq
MIRT1209788	hsa-miR-1827	CLIP-seq
MIRT1209789	hsa-miR-1909	CLIP-seq
MIRT1209790	hsa-miR-1910	CLIP-seq
MIRT1209792	hsa-miR-19a	CLIP-seq
MIRT1209793	hsa-miR-19b	CLIP-seq
MIRT2060168	hsa-miR-2277-3p	CLIP-seq
MIRT2060169	hsa-miR-24	CLIP-seq
MIRT1209796	hsa-miR-2467-3p	CLIP-seq
MIRT1209797	hsa-miR-296-5p	CLIP-seq
MIRT1209800	hsa-miR-3133	CLIP-seq
MIRT1209801	hsa-miR-3135b	CLIP-seq
MIRT2060170	hsa-miR-3160-3p	CLIP-seq
MIRT2060171	hsa-miR-3176	CLIP-seq
MIRT1209808	hsa-miR-3179	CLIP-seq
MIRT1209809	hsa-miR-3184	CLIP-seq
MIRT1209811	hsa-miR-3189-3p	CLIP-seq
MIRT1209812	hsa-miR-3190	CLIP-seq
MIRT1209813	hsa-miR-3192	CLIP-seq
MIRT2060172	hsa-miR-323-5p	CLIP-seq
MIRT2060173	hsa-miR-346	CLIP-seq
MIRT2060174	hsa-miR-3611	CLIP-seq
MIRT1209817	hsa-miR-3612	CLIP-seq
MIRT1209818	hsa-miR-3650	CLIP-seq
MIRT1209819	hsa-miR-3652	CLIP-seq
MIRT1209822	hsa-miR-3689a-3p	CLIP-seq
MIRT1209823	hsa-miR-3689c	CLIP-seq
MIRT2060175	hsa-miR-3689d	CLIP-seq
MIRT2060176	hsa-miR-3691-3p	CLIP-seq
MIRT1209824	hsa-miR-370	CLIP-seq
MIRT2060177	hsa-miR-3922-3p	CLIP-seq
MIRT1209830	hsa-miR-423-5p	CLIP-seq
MIRT1209833	hsa-miR-4264	CLIP-seq
MIRT1209836	hsa-miR-4419a	CLIP-seq
MIRT1209838	hsa-miR-4430	CLIP-seq
MIRT2060178	hsa-miR-4437	CLIP-seq
MIRT1209841	hsa-miR-4443	CLIP-seq
MIRT2060179	hsa-miR-4446-3p	CLIP-seq
MIRT1209842	hsa-miR-4447	CLIP-seq
MIRT2060180	hsa-miR-4455	CLIP-seq
MIRT2060181	hsa-miR-4456	CLIP-seq
MIRT1209843	hsa-miR-4457	CLIP-seq
MIRT1209845	hsa-miR-4462	CLIP-seq
MIRT1209847	hsa-miR-4472	CLIP-seq
MIRT2060182	hsa-miR-4476	CLIP-seq
MIRT1209848	hsa-miR-4483	CLIP-seq
MIRT2060183	hsa-miR-4487	CLIP-seq
MIRT1209850	hsa-miR-4492	CLIP-seq
MIRT2060184	hsa-miR-4493	CLIP-seq
MIRT1209851	hsa-miR-4498	CLIP-seq
MIRT1209852	hsa-miR-4505	CLIP-seq
MIRT1209853	hsa-miR-4510	CLIP-seq
MIRT1209854	hsa-miR-4514	CLIP-seq
MIRT2060185	hsa-miR-4525	CLIP-seq
MIRT2060186	hsa-miR-4527	CLIP-seq
MIRT1209857	hsa-miR-4533	CLIP-seq
MIRT1209858	hsa-miR-455-3p	CLIP-seq
MIRT2060187	hsa-miR-4645-5p	CLIP-seq
MIRT2060188	hsa-miR-4649-3p	CLIP-seq
MIRT1209859	hsa-miR-4651	CLIP-seq
MIRT1209860	hsa-miR-4652-5p	CLIP-seq
MIRT2060189	hsa-miR-4665-5p	CLIP-seq
MIRT2060190	hsa-miR-4670-5p	CLIP-seq
MIRT2060191	hsa-miR-4673	CLIP-seq
MIRT1209866	hsa-miR-4685-5p	CLIP-seq
MIRT1209867	hsa-miR-4692	CLIP-seq
MIRT1209868	hsa-miR-4701-3p	CLIP-seq
MIRT1209869	hsa-miR-4710	CLIP-seq
MIRT1209871	hsa-miR-4717-3p	CLIP-seq
MIRT1209872	hsa-miR-4722-5p	CLIP-seq
MIRT1209873	hsa-miR-4723-5p	CLIP-seq
MIRT1209875	hsa-miR-4728-5p	CLIP-seq
MIRT1209876	hsa-miR-4731-5p	CLIP-seq
MIRT2060192	hsa-miR-4739	CLIP-seq
MIRT1209879	hsa-miR-4747-5p	CLIP-seq
MIRT2060193	hsa-miR-4756-5p	CLIP-seq
MIRT1209882	hsa-miR-4770	CLIP-seq
MIRT1209884	hsa-miR-4779	CLIP-seq
MIRT1209885	hsa-miR-4786-3p	CLIP-seq
MIRT2060194	hsa-miR-4790-3p	CLIP-seq
MIRT2060195	hsa-miR-4792	CLIP-seq
MIRT1209887	hsa-miR-490-3p	CLIP-seq
MIRT2060196	hsa-miR-494	CLIP-seq
MIRT2060197	hsa-miR-515-5p	CLIP-seq
MIRT1209892	hsa-miR-518a-5p	CLIP-seq
MIRT1209893	hsa-miR-527	CLIP-seq
MIRT1209894	hsa-miR-541	CLIP-seq
MIRT1209901	hsa-miR-548b-3p	CLIP-seq
MIRT2060198	hsa-miR-558	CLIP-seq
MIRT1209907	hsa-miR-592	CLIP-seq
MIRT1209909	hsa-miR-597	CLIP-seq
MIRT1209910	hsa-miR-608	CLIP-seq
MIRT1209912	hsa-miR-625	CLIP-seq
MIRT1209914	hsa-miR-637	CLIP-seq
MIRT1209915	hsa-miR-650	CLIP-seq
MIRT2060199	hsa-miR-654-3p	CLIP-seq
MIRT1209916	hsa-miR-654-5p	CLIP-seq
MIRT2060200	hsa-miR-661	CLIP-seq
MIRT1209917	hsa-miR-671-5p	CLIP-seq
MIRT1209920	hsa-miR-762	CLIP-seq
MIRT1209921	hsa-miR-765	CLIP-seq
MIRT2060201	hsa-miR-876-3p	CLIP-seq
MIRT1209924	hsa-miR-940	CLIP-seq
MIRT2288564	hsa-miR-1224-3p	CLIP-seq
MIRT2288565	hsa-miR-1260	CLIP-seq
MIRT2288566	hsa-miR-1260b	CLIP-seq
MIRT1209778	hsa-miR-1262	CLIP-seq
MIRT2060161	hsa-miR-1275	CLIP-seq
MIRT2288567	hsa-miR-1280	CLIP-seq
MIRT1209780	hsa-miR-1287	CLIP-seq
MIRT2060162	hsa-miR-1321	CLIP-seq
MIRT2060163	hsa-miR-1324	CLIP-seq
MIRT1209783	hsa-miR-143	CLIP-seq
MIRT2288568	hsa-miR-1470	CLIP-seq
MIRT2060164	hsa-miR-148a	CLIP-seq
MIRT2060165	hsa-miR-148b	CLIP-seq
MIRT2060166	hsa-miR-152	CLIP-seq
MIRT1209787	hsa-miR-1587	CLIP-seq
MIRT2060167	hsa-miR-1825	CLIP-seq
MIRT1209788	hsa-miR-1827	CLIP-seq
MIRT1209790	hsa-miR-1910	CLIP-seq
MIRT2288569	hsa-miR-2114	CLIP-seq
MIRT2060168	hsa-miR-2277-3p	CLIP-seq
MIRT1209795	hsa-miR-2392	CLIP-seq
MIRT1209796	hsa-miR-2467-3p	CLIP-seq
MIRT1209798	hsa-miR-3064-5p	CLIP-seq
MIRT1209801	hsa-miR-3135b	CLIP-seq
MIRT2288570	hsa-miR-3183	CLIP-seq
MIRT1209809	hsa-miR-3184	CLIP-seq
MIRT1209812	hsa-miR-3190	CLIP-seq
MIRT1209813	hsa-miR-3192	CLIP-seq
MIRT1209814	hsa-miR-3202	CLIP-seq
MIRT2060172	hsa-miR-323-5p	CLIP-seq
MIRT1209815	hsa-miR-342-5p	CLIP-seq
MIRT2060173	hsa-miR-346	CLIP-seq
MIRT1209816	hsa-miR-3605-5p	CLIP-seq
MIRT1209817	hsa-miR-3612	CLIP-seq
MIRT1209819	hsa-miR-3652	CLIP-seq
MIRT2288571	hsa-miR-3678-3p	CLIP-seq
MIRT1209822	hsa-miR-3689a-3p	CLIP-seq
MIRT1209823	hsa-miR-3689c	CLIP-seq
MIRT2060176	hsa-miR-3691-3p	CLIP-seq
MIRT1209824	hsa-miR-370	CLIP-seq
MIRT1209826	hsa-miR-378g	CLIP-seq
MIRT1209830	hsa-miR-423-5p	CLIP-seq
MIRT1209833	hsa-miR-4264	CLIP-seq
MIRT2288572	hsa-miR-4270	CLIP-seq
MIRT2288573	hsa-miR-4279	CLIP-seq
MIRT1209836	hsa-miR-4419a	CLIP-seq
MIRT1209838	hsa-miR-4430	CLIP-seq
MIRT2288574	hsa-miR-4441	CLIP-seq
MIRT2060179	hsa-miR-4446-3p	CLIP-seq
MIRT1209842	hsa-miR-4447	CLIP-seq
MIRT2060180	hsa-miR-4455	CLIP-seq
MIRT1209845	hsa-miR-4462	CLIP-seq
MIRT1209847	hsa-miR-4472	CLIP-seq
MIRT1209850	hsa-miR-4492	CLIP-seq
MIRT1209851	hsa-miR-4498	CLIP-seq
MIRT1209852	hsa-miR-4505	CLIP-seq
MIRT1209853	hsa-miR-4510	CLIP-seq
MIRT2060185	hsa-miR-4525	CLIP-seq
MIRT2060186	hsa-miR-4527	CLIP-seq
MIRT1209857	hsa-miR-4533	CLIP-seq
MIRT1209858	hsa-miR-455-3p	CLIP-seq
MIRT2060188	hsa-miR-4649-3p	CLIP-seq
MIRT1209860	hsa-miR-4652-5p	CLIP-seq
MIRT1209861	hsa-miR-4656	CLIP-seq
MIRT1209862	hsa-miR-4664-5p	CLIP-seq
MIRT2060189	hsa-miR-4665-5p	CLIP-seq
MIRT2288575	hsa-miR-4667-3p	CLIP-seq
MIRT2060190	hsa-miR-4670-5p	CLIP-seq
MIRT1209865	hsa-miR-4675	CLIP-seq
MIRT1209866	hsa-miR-4685-5p	CLIP-seq
MIRT1209868	hsa-miR-4701-3p	CLIP-seq
MIRT1209869	hsa-miR-4710	CLIP-seq
MIRT2288576	hsa-miR-4721	CLIP-seq
MIRT1209872	hsa-miR-4722-5p	CLIP-seq
MIRT2288577	hsa-miR-4723-3p	CLIP-seq
MIRT1209873	hsa-miR-4723-5p	CLIP-seq
MIRT1209875	hsa-miR-4728-5p	CLIP-seq
MIRT1209876	hsa-miR-4731-5p	CLIP-seq
MIRT2060192	hsa-miR-4739	CLIP-seq
MIRT1209877	hsa-miR-4741	CLIP-seq
MIRT1209879	hsa-miR-4747-5p	CLIP-seq
MIRT2060193	hsa-miR-4756-5p	CLIP-seq
MIRT1209882	hsa-miR-4770	CLIP-seq
MIRT1209884	hsa-miR-4779	CLIP-seq
MIRT1209885	hsa-miR-4786-3p	CLIP-seq
MIRT2060194	hsa-miR-4790-3p	CLIP-seq
MIRT1209887	hsa-miR-490-3p	CLIP-seq
MIRT2060196	hsa-miR-494	CLIP-seq
MIRT2060197	hsa-miR-515-5p	CLIP-seq
MIRT2288578	hsa-miR-532-3p	CLIP-seq
MIRT1209894	hsa-miR-541	CLIP-seq
MIRT1209896	hsa-miR-548aa	CLIP-seq
MIRT1209907	hsa-miR-592	CLIP-seq
MIRT1209908	hsa-miR-596	CLIP-seq
MIRT1209909	hsa-miR-597	CLIP-seq
MIRT1209912	hsa-miR-625	CLIP-seq
MIRT1209914	hsa-miR-637	CLIP-seq
MIRT1209915	hsa-miR-650	CLIP-seq
MIRT2060199	hsa-miR-654-3p	CLIP-seq
MIRT1209916	hsa-miR-654-5p	CLIP-seq
MIRT1209917	hsa-miR-671-5p	CLIP-seq
MIRT1209920	hsa-miR-762	CLIP-seq
MIRT1209921	hsa-miR-765	CLIP-seq
MIRT2060201	hsa-miR-876-3p	CLIP-seq
MIRT1209924	hsa-miR-940	CLIP-seq
MIRT2060161	hsa-miR-1275	CLIP-seq
MIRT1209780	hsa-miR-1287	CLIP-seq
MIRT2060163	hsa-miR-1324	CLIP-seq
MIRT1209783	hsa-miR-143	CLIP-seq
MIRT1209790	hsa-miR-1910	CLIP-seq
MIRT1209801	hsa-miR-3135b	CLIP-seq
MIRT1209809	hsa-miR-3184	CLIP-seq
MIRT2060172	hsa-miR-323-5p	CLIP-seq
MIRT1209822	hsa-miR-3689a-3p	CLIP-seq
MIRT1209823	hsa-miR-3689c	CLIP-seq
MIRT1209824	hsa-miR-370	CLIP-seq
MIRT1209830	hsa-miR-423-5p	CLIP-seq
MIRT1209833	hsa-miR-4264	CLIP-seq
MIRT1209836	hsa-miR-4419a	CLIP-seq
MIRT1209842	hsa-miR-4447	CLIP-seq
MIRT1209845	hsa-miR-4462	CLIP-seq
MIRT1209847	hsa-miR-4472	CLIP-seq
MIRT1209853	hsa-miR-4510	CLIP-seq
MIRT2060185	hsa-miR-4525	CLIP-seq
MIRT1209857	hsa-miR-4533	CLIP-seq
MIRT1209858	hsa-miR-455-3p	CLIP-seq
MIRT1209860	hsa-miR-4652-5p	CLIP-seq
MIRT2060189	hsa-miR-4665-5p	CLIP-seq
MIRT1209866	hsa-miR-4685-5p	CLIP-seq
MIRT1209869	hsa-miR-4710	CLIP-seq
MIRT1209873	hsa-miR-4723-5p	CLIP-seq
MIRT1209875	hsa-miR-4728-5p	CLIP-seq
MIRT1209879	hsa-miR-4747-5p	CLIP-seq
MIRT1209882	hsa-miR-4770	CLIP-seq
MIRT1209884	hsa-miR-4779	CLIP-seq
MIRT2060194	hsa-miR-4790-3p	CLIP-seq
MIRT2060195	hsa-miR-4792	CLIP-seq
MIRT2060196	hsa-miR-494	CLIP-seq
MIRT1209894	hsa-miR-541	CLIP-seq
MIRT1209912	hsa-miR-625	CLIP-seq
MIRT1209914	hsa-miR-637	CLIP-seq
MIRT1209916	hsa-miR-654-5p	CLIP-seq
MIRT2060200	hsa-miR-661	CLIP-seq
MIRT1209921	hsa-miR-765	CLIP-seq
MIRT2060201	hsa-miR-876-3p	CLIP-seq
MIRT1209907	hsa-miR-592	CLIP-seq
MIRT1209909	hsa-miR-597	CLIP-seq
MIRT1209918	hsa-miR-676	CLIP-seq
MIRT1209795	hsa-miR-2392	CLIP-seq
MIRT1209798	hsa-miR-3064-5p	CLIP-seq
MIRT1209813	hsa-miR-3192	CLIP-seq
MIRT1209816	hsa-miR-3605-5p	CLIP-seq
MIRT1209819	hsa-miR-3652	CLIP-seq
MIRT1209822	hsa-miR-3689a-3p	CLIP-seq
MIRT1209823	hsa-miR-3689c	CLIP-seq
MIRT1209838	hsa-miR-4430	CLIP-seq
MIRT1209852	hsa-miR-4505	CLIP-seq
MIRT1209875	hsa-miR-4728-5p	CLIP-seq
MIRT1209887	hsa-miR-490-3p	CLIP-seq
MIRT2060163	hsa-miR-1324	CLIP-seq
MIRT1209783	hsa-miR-143	CLIP-seq
MIRT1209809	hsa-miR-3184	CLIP-seq
MIRT2060172	hsa-miR-323-5p	CLIP-seq
MIRT1209822	hsa-miR-3689a-3p	CLIP-seq
MIRT1209823	hsa-miR-3689c	CLIP-seq
MIRT1209830	hsa-miR-423-5p	CLIP-seq
MIRT1209836	hsa-miR-4419a	CLIP-seq
MIRT1209842	hsa-miR-4447	CLIP-seq
MIRT1209845	hsa-miR-4462	CLIP-seq
MIRT1209847	hsa-miR-4472	CLIP-seq
MIRT1209853	hsa-miR-4510	CLIP-seq
MIRT2060188	hsa-miR-4649-3p	CLIP-seq
MIRT1209875	hsa-miR-4728-5p	CLIP-seq
MIRT1209882	hsa-miR-4770	CLIP-seq
MIRT1209884	hsa-miR-4779	CLIP-seq
MIRT2060194	hsa-miR-4790-3p	CLIP-seq
MIRT2060196	hsa-miR-494	CLIP-seq
MIRT1209894	hsa-miR-541	CLIP-seq
MIRT2060199	hsa-miR-654-3p	CLIP-seq
MIRT1209916	hsa-miR-654-5p	CLIP-seq
MIRT1209921	hsa-miR-765	CLIP-seq
MIRT2060201	hsa-miR-876-3p	CLIP-seq
MIRT2060163	hsa-miR-1324	CLIP-seq
MIRT1209783	hsa-miR-143	CLIP-seq
MIRT2060172	hsa-miR-323-5p	CLIP-seq
MIRT1209822	hsa-miR-3689a-3p	CLIP-seq
MIRT1209823	hsa-miR-3689c	CLIP-seq
MIRT1209836	hsa-miR-4419a	CLIP-seq
MIRT1209842	hsa-miR-4447	CLIP-seq
MIRT1209845	hsa-miR-4462	CLIP-seq
MIRT1209847	hsa-miR-4472	CLIP-seq
MIRT1209853	hsa-miR-4510	CLIP-seq
MIRT1209875	hsa-miR-4728-5p	CLIP-seq
MIRT1209882	hsa-miR-4770	CLIP-seq
MIRT1209884	hsa-miR-4779	CLIP-seq
MIRT2060194	hsa-miR-4790-3p	CLIP-seq
MIRT2060196	hsa-miR-494	CLIP-seq
MIRT1209894	hsa-miR-541	CLIP-seq
MIRT1209916	hsa-miR-654-5p	CLIP-seq
MIRT1209921	hsa-miR-765	CLIP-seq
MIRT2060201	hsa-miR-876-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002260	Process	Lymphocyte homeostasis	IEA
GO:0002260	Process	Lymphocyte homeostasis	ISS
GO:0005515	Function	Protein binding	IPI	10707087, 16977309, 17855360, 24001769, 32814053, 34642815
GO:0005794	Component	Golgi apparatus	IEA
GO:0005829	Component	Cytosol	TAS
GO:0030137	Component	COPI-coated vesicle	IEA
GO:0034067	Process	Protein localization to Golgi apparatus	IEA
GO:0044325	Function	Transmembrane transporter binding	IBA
GO:0044325	Function	Transmembrane transporter binding	IPI	15692563
GO:0072659	Process	Protein localization to plasma membrane	IBA
GO:0072659	Process	Protein localization to plasma membrane	IMP	15692563

Other IDs

• MIM: 607492
• HGNC: 30032
• e!Ensembl: ENSG00000175115

Protein

• UniProt ID: Q6VY07
• Protein name: Phosphofurin acidic cluster sorting protein 1 (PACS-1)
• Protein function: Coat protein that is involved in the localization of trans-Golgi network (TGN) membrane proteins that contain acidic cluster sorting motifs. Controls the endosome-to-Golgi trafficking of furin and mannose-6-phosphate receptor by connecting the a
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF10254	Pacs-1	548 → 960	PACS-1 cytosolic sorting protein	Family

• Sequence:

  MAERGGAGGGPGGAGGGSGQRGSGVAQSPQQPPPQQQQQQPPQQPTPPKLAQATSSSSST
  SAAAASSSSSSTSTSMAVAVASGSAPPGGPGPGRTPAPVQMNLYATWEVDRSSSSCVPRL
  FSLTLKKLVMLKEMDKDLNSVVIAVKLQGSKRILRSNEIVLPASGLVETELQLTFSLQYP
  HFLKRDANKLQIMLQRRKRYKNRTILGYKTLAVGLINMAEVMQHPNEGALVLGLHSNVKD
  VSVPVAEIKIYSLSSQPIDHEGIKSKLSDRSPDIDNYSEEEEESFSSEQEGSDDPLHGQD
  LFYEDEDLRKVKKTRRKLTSTSAITRQPNIKQKFVALLKRFKVSDEVGFGLEHVSREQIR
  EVEEDLDELYDSLEMYNPSDSGPEMEETESILSTPKPKLKPFFEGMSQSSSQTEIGSLNS
  KGSLGKDTTSPMELAALEKIKSTWIKNQDDSLTETDTLEITDQDMFGDASTSLVVPEKVK
  TPMKSSKTDLQGSASPSKVEGVHTPRQKRSTPLKERQLSKPLSERTNSSDSERSPDLGHS
  TQIPRKVVYDQLNQILVSDAALPENVILVNTTDWQGQYVAELLQDQRKPVVCTCSTVEVQ
  AVLSALLTRIQRYCNCNSSMPRPVKVAAVGGQSYLSSILRFFVKSLANKTSDWLGYMRFL
  IIPLGSHPVAKYLGSVDSKYSSSFLDSGWRDLFSRSEPPVSEQLDVAGRVMQYVNGAATT
  HQLPVAEAMLTCRHKFPDEDSYQKFIPFIGVVKVGLVEDSPSTAGDGDDSPVVSLTVPST
  SPPSSSGLSRDATATPPSSPSMSSALAIVGSPNSPYGDVIGLQVDYWLGHPGERRREGDK
  RDASSKNTLKSVFRSVQVSRLPHSGEAQLSGTMAMTVVTKEKNKKVPTIFLSKKPREKEV
  DSKSQVIEGISRLICSAKQQQTMLRVSIDGVEWSDIKFFQLAAQWPTHVKHFPVGLFSGS
  KAT

• Sequence length: 963

Pathways

Reactome:

Nef mediated downregulation of MHC class I complex cell surface expression

Associated diseases

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Global developmental delay	Likely pathogenic; Pathogenic	rs398123009	RCV001255394
Intellectual disability	Likely pathogenic; Pathogenic	rs2495549778, rs398123009	RCV002463874 RCV001310258
Neurodevelopmental disorder	Likely pathogenic; Pathogenic	rs398123009	RCV001375021
PACS1-related disorder	Likely pathogenic; Pathogenic	rs398123009	RCV003398585
PACS1-related syndrome	Likely pathogenic; Pathogenic	rs398123009	RCV001095741
Schuurs-Hoeijmakers syndrome	Pathogenic; Likely pathogenic	rs2134735819, rs2495230982, rs398123009	RCV002250169 RCV002465456 RCV000032781
See cases	Likely pathogenic; Pathogenic	rs398123009	RCV002251940

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Acute myeloid leukemia	Benign	rs572697	RCV005889173
Aganglionic megacolon	Likely benign	rs750459659	RCV000984692
Cervical cancer	Benign; Likely benign	rs572697, rs79265330	RCV005889174 RCV005901855
Cholangiocarcinoma	Benign	rs2236652	RCV005922945
Clear cell carcinoma of kidney	Benign	rs572697	RCV005889175
Colon adenocarcinoma	Benign; Likely benign	rs572697, rs79265330	RCV005889172 RCV005901853
Colorectal cancer	Benign	rs572697	RCV005889176
Gastric cancer	Benign	rs572697	RCV005889178
Hypospadias	Uncertain significance	rs762496747	RCV001824102
Lung cancer	Benign; Likely benign	rs572697, rs79265330	RCV005889181 RCV005901856
Malignant lymphoma, large B-cell, diffuse	Benign	rs2236652	RCV005922944
Malignant tumor of esophagus	Benign; Likely benign	rs79265330	RCV005901854
Malignant tumor of urinary bladder	Likely benign	rs773764695	RCV005899885
Ovarian serous cystadenocarcinoma	Benign	rs572697	RCV005889179
Sarcoma	Benign	rs572697	RCV005889177
Schizophrenia	Uncertain significance	rs2495606343	RCV002463550
Thyroid cancer, nonmedullary, 1	Benign	rs572697	RCV005889180
Uterine corpus endometrial carcinoma	Benign	rs572697	RCV005889182

Associations from Text Mining
Disease Name	Relationship Type	References
Autism Spectrum Disorder	Associate	34948243
Autistic Disorder	Associate	34517877
Cluster Headache	Associate	38280846
Developmental Disabilities	Associate	34068396, 34517877
Ductus Arteriosus Patent	Associate	28111752
Epilepsy	Associate	34517877
Facial Dysmorphism with Multiple Malformations	Associate	30568311
Intellectual Disability	Associate	28111752, 34517877, 38521709
Obesity	Associate	23563609, 28564656
Obsessive Compulsive Disorder	Associate	28111752
Seizures	Associate	28111752
Stomach Neoplasms	Inhibit	29670108
Syndrome	Associate	34068396, 40004556
Uterine Cervical Neoplasms	Associate	33028635