YEATS2 (YEATS domain containing 2)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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55689 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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YEATS domain containing 2 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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YEATS2 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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FAME4 |
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Chromosome
Chromosome number
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3 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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3q27.1 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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Summary: The protein encoded by this gene is a scaffolding subunit of the ATAC complex, which is a complex with acetyltransferase activity on histones H3 and H4. Alternative splicing results in multiple transcript variants encoding different isoforms. [pr |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q9ULM3 | ||||||||||
| Protein name | YEATS domain-containing protein 2 | ||||||||||
| Protein function | Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (PubMed:18838386, PubMed:19103755, PubMed:27103431). YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys | ||||||||||
| PDB | 5IQL , 5XNV , 6LSD , 7EIE | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 1422 | ||||||||||
| Interactions | View interactions | ||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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