Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	5563
Gene name	Protein kinase AMP-activated catalytic subunit alpha 2
Gene symbol	PRKAA2
Synonyms (NCBI Gene)	AMPKAMPK2AMPKa2PRKAA
Chromosome	1
Chromosome location	1p32.2
Summary	The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that

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miRTarBase ID	miRNA	Experiments	Reference
MIRT026874	hsa-miR-192-5p	Microarray	19074876
MIRT027841	hsa-miR-98-5p	Microarray	19088304
MIRT052107	hsa-let-7b-5p	CLASH	23622248
MIRT047217	hsa-miR-182-5p	CLASH	23622248
MIRT700623	hsa-miR-495-5p	HITS-CLIP	23313552
MIRT700622	hsa-miR-4761-5p	HITS-CLIP	23313552
MIRT700621	hsa-miR-8060	HITS-CLIP	23313552
MIRT700620	hsa-miR-494-3p	HITS-CLIP	23313552
MIRT700619	hsa-miR-3166	HITS-CLIP	23313552
MIRT700618	hsa-miR-4771	HITS-CLIP	23313552
MIRT700617	hsa-miR-3653-3p	HITS-CLIP	23313552
MIRT700616	hsa-miR-7154-5p	HITS-CLIP	23313552
MIRT700615	hsa-miR-1273h-3p	HITS-CLIP	23313552
MIRT700614	hsa-miR-3678-3p	HITS-CLIP	23313552
MIRT700613	hsa-miR-3658	HITS-CLIP	23313552
MIRT654776	hsa-miR-141-3p	HITS-CLIP	23824327
MIRT654775	hsa-miR-200a-3p	HITS-CLIP	23824327
MIRT654774	hsa-miR-500a-5p	HITS-CLIP	23824327
MIRT654773	hsa-miR-382-3p	HITS-CLIP	23824327
MIRT654772	hsa-miR-4719	HITS-CLIP	23824327
MIRT654771	hsa-miR-4729	HITS-CLIP	23824327
MIRT654770	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT654769	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT449658	hsa-miR-5696	HITS-CLIP	23824327
MIRT654768	hsa-miR-302c-5p	HITS-CLIP	23824327
MIRT555220	hsa-miR-7844-5p	PAR-CLIP	21572407
MIRT281967	hsa-miR-4804-3p	PAR-CLIP	21572407
MIRT281965	hsa-miR-4720-3p	PAR-CLIP	21572407
MIRT449663	hsa-miR-1250-3p	PAR-CLIP	22100165
MIRT449662	hsa-miR-153-5p	PAR-CLIP	22100165
MIRT449661	hsa-miR-26b-3p	PAR-CLIP	22100165
MIRT449660	hsa-miR-4635	PAR-CLIP	22100165
MIRT449659	hsa-miR-1206	PAR-CLIP	22100165
MIRT449657	hsa-miR-6853-3p	PAR-CLIP	22100165
MIRT449658	hsa-miR-5696	PAR-CLIP	22100165
MIRT449656	hsa-miR-579-3p	PAR-CLIP	22100165
MIRT449655	hsa-miR-664b-3p	PAR-CLIP	22100165
MIRT449654	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT449653	hsa-miR-578	PAR-CLIP	22100165
MIRT449652	hsa-miR-510-3p	PAR-CLIP	22100165
MIRT731819	hsa-miR-27a-3p	Luciferase reporter assayWestern blot	27779715
MIRT731819	hsa-miR-27a-3p	Luciferase reporter assayWestern blot	27779715
MIRT734738	hsa-miR-124-3p	Luciferase reporter assayMicroarray	33681194
MIRT700623	hsa-miR-495-5p	HITS-CLIP	23313552
MIRT700622	hsa-miR-4761-5p	HITS-CLIP	23313552
MIRT700621	hsa-miR-8060	HITS-CLIP	23313552
MIRT700620	hsa-miR-494-3p	HITS-CLIP	23313552
MIRT700619	hsa-miR-3166	HITS-CLIP	23313552
MIRT700618	hsa-miR-4771	HITS-CLIP	23313552
MIRT700617	hsa-miR-3653-3p	HITS-CLIP	23313552
MIRT700616	hsa-miR-7154-5p	HITS-CLIP	23313552
MIRT700615	hsa-miR-1273h-3p	HITS-CLIP	23313552
MIRT700614	hsa-miR-3678-3p	HITS-CLIP	23313552
MIRT700613	hsa-miR-3658	HITS-CLIP	23313552
MIRT654776	hsa-miR-141-3p	HITS-CLIP	23824327
MIRT654775	hsa-miR-200a-3p	HITS-CLIP	23824327
MIRT654774	hsa-miR-500a-5p	HITS-CLIP	23824327
MIRT654773	hsa-miR-382-3p	HITS-CLIP	23824327
MIRT654772	hsa-miR-4719	HITS-CLIP	23824327
MIRT654771	hsa-miR-4729	HITS-CLIP	23824327
MIRT654770	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT654769	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT449658	hsa-miR-5696	HITS-CLIP	23824327
MIRT654768	hsa-miR-302c-5p	HITS-CLIP	23824327
MIRT555220	hsa-miR-7844-5p	PAR-CLIP	21572407
MIRT281967	hsa-miR-4804-3p	PAR-CLIP	21572407
MIRT281965	hsa-miR-4720-3p	PAR-CLIP	21572407
MIRT449663	hsa-miR-1250-3p	PAR-CLIP	22100165
MIRT449662	hsa-miR-153-5p	PAR-CLIP	22100165
MIRT449661	hsa-miR-26b-3p	PAR-CLIP	22100165
MIRT449660	hsa-miR-4635	PAR-CLIP	22100165
MIRT449659	hsa-miR-1206	PAR-CLIP	22100165
MIRT449657	hsa-miR-6853-3p	PAR-CLIP	22100165
MIRT449658	hsa-miR-5696	PAR-CLIP	22100165
MIRT449656	hsa-miR-579-3p	PAR-CLIP	22100165
MIRT449655	hsa-miR-664b-3p	PAR-CLIP	22100165
MIRT449654	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT449653	hsa-miR-578	PAR-CLIP	22100165
MIRT449652	hsa-miR-510-3p	PAR-CLIP	22100165
MIRT739556	hsa-miR-10a	CLIP-seq
MIRT739555	hsa-miR-10b	CLIP-seq
MIRT1261931	hsa-miR-1208	CLIP-seq
MIRT1261932	hsa-miR-1265	CLIP-seq
MIRT1261933	hsa-miR-1267	CLIP-seq
MIRT1261934	hsa-miR-128	CLIP-seq
MIRT1261935	hsa-miR-1283	CLIP-seq
MIRT1261936	hsa-miR-1286	CLIP-seq
MIRT1261937	hsa-miR-1288	CLIP-seq
MIRT1261938	hsa-miR-129-5p	CLIP-seq
MIRT1261939	hsa-miR-130a	CLIP-seq
MIRT1261940	hsa-miR-130b	CLIP-seq
MIRT1261941	hsa-miR-134	CLIP-seq
MIRT1261942	hsa-miR-137	CLIP-seq
MIRT1261943	hsa-miR-1827	CLIP-seq
MIRT1261944	hsa-miR-186	CLIP-seq
MIRT1261945	hsa-miR-1915	CLIP-seq
MIRT739557	hsa-miR-203	CLIP-seq
MIRT1261946	hsa-miR-2053	CLIP-seq
MIRT1261947	hsa-miR-214	CLIP-seq
MIRT1261948	hsa-miR-216b	CLIP-seq
MIRT1261949	hsa-miR-218	CLIP-seq
MIRT1261950	hsa-miR-2392	CLIP-seq
MIRT1261951	hsa-miR-25	CLIP-seq
MIRT1261952	hsa-miR-27a	CLIP-seq
MIRT1261953	hsa-miR-27b	CLIP-seq
MIRT1261954	hsa-miR-301a	CLIP-seq
MIRT1261955	hsa-miR-301b	CLIP-seq
MIRT1261956	hsa-miR-3118	CLIP-seq
MIRT1261957	hsa-miR-3157-3p	CLIP-seq
MIRT1261958	hsa-miR-3164	CLIP-seq
MIRT1261959	hsa-miR-3169	CLIP-seq
MIRT1261960	hsa-miR-3173-3p	CLIP-seq
MIRT1261961	hsa-miR-32	CLIP-seq
MIRT1261962	hsa-miR-320a	CLIP-seq
MIRT1261963	hsa-miR-320b	CLIP-seq
MIRT1261964	hsa-miR-320c	CLIP-seq
MIRT1261965	hsa-miR-320d	CLIP-seq
MIRT1261966	hsa-miR-323-3p	CLIP-seq
MIRT1261967	hsa-miR-330-3p	CLIP-seq
MIRT1261968	hsa-miR-335	CLIP-seq
MIRT1261969	hsa-miR-34c-3p	CLIP-seq
MIRT1261970	hsa-miR-3591-3p	CLIP-seq
MIRT1261971	hsa-miR-3611	CLIP-seq
MIRT1261972	hsa-miR-3612	CLIP-seq
MIRT1261973	hsa-miR-3613-3p	CLIP-seq
MIRT1261974	hsa-miR-3619-5p	CLIP-seq
MIRT1261975	hsa-miR-3622b-5p	CLIP-seq
MIRT1261976	hsa-miR-362-5p	CLIP-seq
MIRT1261977	hsa-miR-363	CLIP-seq
MIRT1261978	hsa-miR-3646	CLIP-seq
MIRT1261979	hsa-miR-3666	CLIP-seq
MIRT1261980	hsa-miR-367	CLIP-seq
MIRT1261981	hsa-miR-3672	CLIP-seq
MIRT1261982	hsa-miR-3674	CLIP-seq
MIRT1261983	hsa-miR-3685	CLIP-seq
MIRT1261984	hsa-miR-3691-3p	CLIP-seq
MIRT1261985	hsa-miR-376a	CLIP-seq
MIRT1261986	hsa-miR-376b	CLIP-seq
MIRT1261987	hsa-miR-3919	CLIP-seq
MIRT1261988	hsa-miR-410	CLIP-seq
MIRT1261989	hsa-miR-4266	CLIP-seq
MIRT1261990	hsa-miR-4282	CLIP-seq
MIRT1261991	hsa-miR-4295	CLIP-seq
MIRT1261992	hsa-miR-4326	CLIP-seq
MIRT1261993	hsa-miR-4427	CLIP-seq
MIRT1261994	hsa-miR-4428	CLIP-seq
MIRT1261995	hsa-miR-4429	CLIP-seq
MIRT1261996	hsa-miR-4477a	CLIP-seq
MIRT1261997	hsa-miR-4501	CLIP-seq
MIRT1261998	hsa-miR-4521	CLIP-seq
MIRT1261999	hsa-miR-454	CLIP-seq
MIRT1262000	hsa-miR-4671-3p	CLIP-seq
MIRT1262001	hsa-miR-4680-3p	CLIP-seq
MIRT1262002	hsa-miR-4694-3p	CLIP-seq
MIRT1262003	hsa-miR-4694-5p	CLIP-seq
MIRT1262004	hsa-miR-4695-5p	CLIP-seq
MIRT1262005	hsa-miR-4709-3p	CLIP-seq
MIRT1262006	hsa-miR-4726-3p	CLIP-seq
MIRT1262007	hsa-miR-4738-3p	CLIP-seq
MIRT1262008	hsa-miR-4756-3p	CLIP-seq
MIRT1262009	hsa-miR-4764-5p	CLIP-seq
MIRT1262010	hsa-miR-4768-3p	CLIP-seq
MIRT1262011	hsa-miR-4775	CLIP-seq
MIRT1262012	hsa-miR-4779	CLIP-seq
MIRT1262013	hsa-miR-4793-5p	CLIP-seq
MIRT1262014	hsa-miR-4803	CLIP-seq
MIRT1262015	hsa-miR-494	CLIP-seq
MIRT1262016	hsa-miR-500b	CLIP-seq
MIRT1262017	hsa-miR-501-5p	CLIP-seq
MIRT1262018	hsa-miR-513a-5p	CLIP-seq
MIRT1262019	hsa-miR-548ae	CLIP-seq
MIRT1262020	hsa-miR-548ag	CLIP-seq
MIRT1262021	hsa-miR-548ai	CLIP-seq
MIRT1262022	hsa-miR-548aj	CLIP-seq
MIRT1262023	hsa-miR-548am	CLIP-seq
MIRT1262024	hsa-miR-548c-3p	CLIP-seq
MIRT1262025	hsa-miR-548x	CLIP-seq
MIRT1262026	hsa-miR-569	CLIP-seq
MIRT1262027	hsa-miR-579	CLIP-seq
MIRT1262028	hsa-miR-581	CLIP-seq
MIRT1262029	hsa-miR-589	CLIP-seq
MIRT1262030	hsa-miR-599	CLIP-seq
MIRT1262031	hsa-miR-606	CLIP-seq
MIRT1262032	hsa-miR-616	CLIP-seq
MIRT1262033	hsa-miR-642b	CLIP-seq
MIRT1262034	hsa-miR-650	CLIP-seq
MIRT1262035	hsa-miR-670	CLIP-seq
MIRT1262036	hsa-miR-758	CLIP-seq
MIRT1262037	hsa-miR-761	CLIP-seq
MIRT1262038	hsa-miR-92a	CLIP-seq
MIRT1262039	hsa-miR-92b	CLIP-seq
MIRT1262040	hsa-miR-944	CLIP-seq
MIRT2077186	hsa-miR-1246	CLIP-seq
MIRT2077187	hsa-miR-1290	CLIP-seq
MIRT1261938	hsa-miR-129-5p	CLIP-seq
MIRT2077188	hsa-miR-1299	CLIP-seq
MIRT739557	hsa-miR-203	CLIP-seq
MIRT1261947	hsa-miR-214	CLIP-seq
MIRT1261958	hsa-miR-3164	CLIP-seq
MIRT2077189	hsa-miR-3167	CLIP-seq
MIRT1261974	hsa-miR-3619-5p	CLIP-seq
MIRT1261975	hsa-miR-3622b-5p	CLIP-seq
MIRT2077190	hsa-miR-375	CLIP-seq
MIRT2077191	hsa-miR-3977	CLIP-seq
MIRT2077192	hsa-miR-4291	CLIP-seq
MIRT2077193	hsa-miR-4307	CLIP-seq
MIRT1261992	hsa-miR-4326	CLIP-seq
MIRT2077194	hsa-miR-4503	CLIP-seq
MIRT2077195	hsa-miR-4691-5p	CLIP-seq
MIRT2077196	hsa-miR-4720-5p	CLIP-seq
MIRT1262011	hsa-miR-4775	CLIP-seq
MIRT2077197	hsa-miR-4799-3p	CLIP-seq
MIRT2077198	hsa-miR-548aa	CLIP-seq
MIRT2077199	hsa-miR-548ac	CLIP-seq
MIRT1262019	hsa-miR-548ae	CLIP-seq
MIRT1262022	hsa-miR-548aj	CLIP-seq
MIRT1262023	hsa-miR-548am	CLIP-seq
MIRT2077200	hsa-miR-548d-3p	CLIP-seq
MIRT1262025	hsa-miR-548x	CLIP-seq
MIRT2077201	hsa-miR-548z	CLIP-seq
MIRT2077202	hsa-miR-561	CLIP-seq
MIRT2077203	hsa-miR-582-3p	CLIP-seq
MIRT2077204	hsa-miR-607	CLIP-seq
MIRT1262037	hsa-miR-761	CLIP-seq
MIRT2077205	hsa-miR-876-5p	CLIP-seq
MIRT2077206	hsa-miR-922	CLIP-seq
MIRT2303658	hsa-let-7a	CLIP-seq
MIRT2303659	hsa-let-7b	CLIP-seq
MIRT2303660	hsa-let-7c	CLIP-seq
MIRT2303661	hsa-let-7d	CLIP-seq
MIRT2303662	hsa-let-7e	CLIP-seq
MIRT2303663	hsa-let-7f	CLIP-seq
MIRT2303664	hsa-let-7g	CLIP-seq
MIRT2303665	hsa-let-7i	CLIP-seq
MIRT2303666	hsa-miR-106a	CLIP-seq
MIRT2303667	hsa-miR-106b	CLIP-seq
MIRT1261932	hsa-miR-1265	CLIP-seq
MIRT2303668	hsa-miR-1284	CLIP-seq
MIRT1261936	hsa-miR-1286	CLIP-seq
MIRT1261937	hsa-miR-1288	CLIP-seq
MIRT2303669	hsa-miR-1294	CLIP-seq
MIRT1261939	hsa-miR-130a	CLIP-seq
MIRT1261940	hsa-miR-130b	CLIP-seq
MIRT2303670	hsa-miR-141	CLIP-seq
MIRT2303671	hsa-miR-142-5p	CLIP-seq
MIRT2303672	hsa-miR-154	CLIP-seq
MIRT2303673	hsa-miR-17	CLIP-seq
MIRT2303674	hsa-miR-181a	CLIP-seq
MIRT2303675	hsa-miR-181b	CLIP-seq
MIRT2303676	hsa-miR-181c	CLIP-seq
MIRT2303677	hsa-miR-181d	CLIP-seq
MIRT2303678	hsa-miR-200a	CLIP-seq
MIRT2303679	hsa-miR-202	CLIP-seq
MIRT2303680	hsa-miR-20a	CLIP-seq
MIRT2303681	hsa-miR-20b	CLIP-seq
MIRT1261947	hsa-miR-214	CLIP-seq
MIRT1261950	hsa-miR-2392	CLIP-seq
MIRT2303682	hsa-miR-23a	CLIP-seq
MIRT2303683	hsa-miR-23b	CLIP-seq
MIRT2303684	hsa-miR-23c	CLIP-seq
MIRT1261951	hsa-miR-25	CLIP-seq
MIRT2303685	hsa-miR-300	CLIP-seq
MIRT1261954	hsa-miR-301a	CLIP-seq
MIRT1261955	hsa-miR-301b	CLIP-seq
MIRT2303686	hsa-miR-302a	CLIP-seq
MIRT2303687	hsa-miR-302b	CLIP-seq
MIRT2303688	hsa-miR-302c	CLIP-seq
MIRT2303689	hsa-miR-302d	CLIP-seq
MIRT2303690	hsa-miR-302e	CLIP-seq
MIRT2303691	hsa-miR-31	CLIP-seq
MIRT2303692	hsa-miR-3143	CLIP-seq
MIRT2303693	hsa-miR-3145-3p	CLIP-seq
MIRT2303694	hsa-miR-3163	CLIP-seq
MIRT1261958	hsa-miR-3164	CLIP-seq
MIRT1261959	hsa-miR-3169	CLIP-seq
MIRT2303695	hsa-miR-3194-5p	CLIP-seq
MIRT1261961	hsa-miR-32	CLIP-seq
MIRT1261962	hsa-miR-320a	CLIP-seq
MIRT1261963	hsa-miR-320b	CLIP-seq
MIRT1261964	hsa-miR-320c	CLIP-seq
MIRT1261965	hsa-miR-320d	CLIP-seq
MIRT2303696	hsa-miR-340	CLIP-seq
MIRT1261969	hsa-miR-34c-3p	CLIP-seq
MIRT1261974	hsa-miR-3619-5p	CLIP-seq
MIRT1261975	hsa-miR-3622b-5p	CLIP-seq
MIRT1261977	hsa-miR-363	CLIP-seq
MIRT1261979	hsa-miR-3666	CLIP-seq
MIRT1261980	hsa-miR-367	CLIP-seq
MIRT1261984	hsa-miR-3691-3p	CLIP-seq
MIRT2303697	hsa-miR-372	CLIP-seq
MIRT2303698	hsa-miR-373	CLIP-seq
MIRT2077190	hsa-miR-375	CLIP-seq
MIRT1261985	hsa-miR-376a	CLIP-seq
MIRT1261986	hsa-miR-376b	CLIP-seq
MIRT2303699	hsa-miR-381	CLIP-seq
MIRT2303700	hsa-miR-3945	CLIP-seq
MIRT2303701	hsa-miR-3973	CLIP-seq
MIRT2303702	hsa-miR-4262	CLIP-seq
MIRT2303703	hsa-miR-4276	CLIP-seq
MIRT1261990	hsa-miR-4282	CLIP-seq
MIRT1261991	hsa-miR-4295	CLIP-seq
MIRT2303704	hsa-miR-4311	CLIP-seq
MIRT2303705	hsa-miR-4316	CLIP-seq
MIRT2303706	hsa-miR-4420	CLIP-seq
MIRT1261995	hsa-miR-4429	CLIP-seq
MIRT2303707	hsa-miR-4458	CLIP-seq
MIRT2303708	hsa-miR-4464	CLIP-seq
MIRT2303709	hsa-miR-4495	CLIP-seq
MIRT2303710	hsa-miR-4500	CLIP-seq
MIRT2303711	hsa-miR-452	CLIP-seq
MIRT1261999	hsa-miR-454	CLIP-seq
MIRT2303712	hsa-miR-4642	CLIP-seq
MIRT2303713	hsa-miR-4666-3p	CLIP-seq
MIRT1262000	hsa-miR-4671-3p	CLIP-seq
MIRT2303714	hsa-miR-4676-3p	CLIP-seq
MIRT2303715	hsa-miR-4677-3p	CLIP-seq
MIRT2303716	hsa-miR-4677-5p	CLIP-seq
MIRT2303717	hsa-miR-4679	CLIP-seq
MIRT2303718	hsa-miR-4693-5p	CLIP-seq
MIRT2303719	hsa-miR-4704-3p	CLIP-seq
MIRT2303720	hsa-miR-4705	CLIP-seq
MIRT2077196	hsa-miR-4720-5p	CLIP-seq
MIRT1262007	hsa-miR-4738-3p	CLIP-seq
MIRT2303721	hsa-miR-4748	CLIP-seq
MIRT2303722	hsa-miR-4773	CLIP-seq
MIRT2303723	hsa-miR-4795-3p	CLIP-seq
MIRT2077197	hsa-miR-4799-3p	CLIP-seq
MIRT2303724	hsa-miR-512-3p	CLIP-seq
MIRT2303725	hsa-miR-519d	CLIP-seq
MIRT2303726	hsa-miR-520a-3p	CLIP-seq
MIRT2303727	hsa-miR-520b	CLIP-seq
MIRT2303728	hsa-miR-520c-3p	CLIP-seq
MIRT2303729	hsa-miR-520d-3p	CLIP-seq
MIRT2303730	hsa-miR-520e	CLIP-seq
MIRT2303731	hsa-miR-520g	CLIP-seq
MIRT2303732	hsa-miR-520h	CLIP-seq
MIRT1262024	hsa-miR-548c-3p	CLIP-seq
MIRT2303733	hsa-miR-548m	CLIP-seq
MIRT2303734	hsa-miR-633	CLIP-seq
MIRT2303735	hsa-miR-759	CLIP-seq
MIRT1262037	hsa-miR-761	CLIP-seq
MIRT1262038	hsa-miR-92a	CLIP-seq
MIRT1262039	hsa-miR-92b	CLIP-seq
MIRT2303736	hsa-miR-93	CLIP-seq
MIRT2303737	hsa-miR-98	CLIP-seq
MIRT2077188	hsa-miR-1299	CLIP-seq
MIRT2392964	hsa-miR-147	CLIP-seq
MIRT2392965	hsa-miR-4289	CLIP-seq
MIRT2392966	hsa-miR-4470	CLIP-seq
MIRT2392967	hsa-miR-4749-3p	CLIP-seq
MIRT2392968	hsa-miR-875-3p	CLIP-seq
MIRT2303722	hsa-miR-4773	CLIP-seq
MIRT1262019	hsa-miR-548ae	CLIP-seq
MIRT1262022	hsa-miR-548aj	CLIP-seq
MIRT1262023	hsa-miR-548am	CLIP-seq
MIRT1262025	hsa-miR-548x	CLIP-seq
MIRT2303674	hsa-miR-181a	CLIP-seq
MIRT2303675	hsa-miR-181b	CLIP-seq
MIRT2303676	hsa-miR-181c	CLIP-seq
MIRT2303677	hsa-miR-181d	CLIP-seq
MIRT2465908	hsa-miR-3938	CLIP-seq
MIRT2303702	hsa-miR-4262	CLIP-seq
MIRT2303658	hsa-let-7a	CLIP-seq
MIRT2303659	hsa-let-7b	CLIP-seq
MIRT2303660	hsa-let-7c	CLIP-seq
MIRT2303661	hsa-let-7d	CLIP-seq
MIRT2303662	hsa-let-7e	CLIP-seq
MIRT2303663	hsa-let-7f	CLIP-seq
MIRT2303664	hsa-let-7g	CLIP-seq
MIRT2303665	hsa-let-7i	CLIP-seq
MIRT1261931	hsa-miR-1208	CLIP-seq
MIRT2077186	hsa-miR-1246	CLIP-seq
MIRT2600382	hsa-miR-1255a	CLIP-seq
MIRT2600383	hsa-miR-1255b	CLIP-seq
MIRT2600384	hsa-miR-1256	CLIP-seq
MIRT1261933	hsa-miR-1267	CLIP-seq
MIRT2303669	hsa-miR-1294	CLIP-seq
MIRT1261942	hsa-miR-137	CLIP-seq
MIRT2600385	hsa-miR-139-5p	CLIP-seq
MIRT2303672	hsa-miR-154	CLIP-seq
MIRT2600386	hsa-miR-1913	CLIP-seq
MIRT1261945	hsa-miR-1915	CLIP-seq
MIRT2600387	hsa-miR-197	CLIP-seq
MIRT2303679	hsa-miR-202	CLIP-seq
MIRT739557	hsa-miR-203	CLIP-seq
MIRT1261948	hsa-miR-216b	CLIP-seq
MIRT1261951	hsa-miR-25	CLIP-seq
MIRT2600388	hsa-miR-3065-5p	CLIP-seq
MIRT2600389	hsa-miR-30a	CLIP-seq
MIRT2600390	hsa-miR-30b	CLIP-seq
MIRT2600391	hsa-miR-30c	CLIP-seq
MIRT2600392	hsa-miR-30d	CLIP-seq
MIRT2600393	hsa-miR-30e	CLIP-seq
MIRT2600394	hsa-miR-3133	CLIP-seq
MIRT2303692	hsa-miR-3143	CLIP-seq
MIRT2600395	hsa-miR-3148	CLIP-seq
MIRT2600396	hsa-miR-3155	CLIP-seq
MIRT2600397	hsa-miR-3155b	CLIP-seq
MIRT1261958	hsa-miR-3164	CLIP-seq
MIRT2600398	hsa-miR-3185	CLIP-seq
MIRT2600399	hsa-miR-3187-3p	CLIP-seq
MIRT2600400	hsa-miR-3199	CLIP-seq
MIRT1261961	hsa-miR-32	CLIP-seq
MIRT2600401	hsa-miR-324-3p	CLIP-seq
MIRT1261968	hsa-miR-335	CLIP-seq
MIRT2600402	hsa-miR-33a	CLIP-seq
MIRT2600403	hsa-miR-33b	CLIP-seq
MIRT2600404	hsa-miR-34a	CLIP-seq
MIRT1261969	hsa-miR-34c-3p	CLIP-seq
MIRT2600405	hsa-miR-34c-5p	CLIP-seq
MIRT1261973	hsa-miR-3613-3p	CLIP-seq
MIRT2600406	hsa-miR-361-5p	CLIP-seq
MIRT1261975	hsa-miR-3622b-5p	CLIP-seq
MIRT1261977	hsa-miR-363	CLIP-seq
MIRT1261978	hsa-miR-3646	CLIP-seq
MIRT2600407	hsa-miR-3663-5p	CLIP-seq
MIRT1261980	hsa-miR-367	CLIP-seq
MIRT2600408	hsa-miR-3688-3p	CLIP-seq
MIRT2600409	hsa-miR-374c	CLIP-seq
MIRT2600410	hsa-miR-377	CLIP-seq
MIRT2077191	hsa-miR-3977	CLIP-seq
MIRT2600411	hsa-miR-411	CLIP-seq
MIRT2600412	hsa-miR-4293	CLIP-seq
MIRT2600413	hsa-miR-4305	CLIP-seq
MIRT2303705	hsa-miR-4316	CLIP-seq
MIRT2600414	hsa-miR-4320	CLIP-seq
MIRT2600415	hsa-miR-4327	CLIP-seq
MIRT2600416	hsa-miR-4328	CLIP-seq
MIRT2600417	hsa-miR-4435	CLIP-seq
MIRT2600418	hsa-miR-4438	CLIP-seq
MIRT2600419	hsa-miR-4453	CLIP-seq
MIRT2303707	hsa-miR-4458	CLIP-seq
MIRT2600420	hsa-miR-4463	CLIP-seq
MIRT2600421	hsa-miR-4474-5p	CLIP-seq
MIRT2600422	hsa-miR-4475	CLIP-seq
MIRT2600423	hsa-miR-4477b	CLIP-seq
MIRT2600424	hsa-miR-4494	CLIP-seq
MIRT2600425	hsa-miR-449a	CLIP-seq
MIRT2600426	hsa-miR-449b	CLIP-seq
MIRT2303710	hsa-miR-4500	CLIP-seq
MIRT2077194	hsa-miR-4503	CLIP-seq
MIRT2600427	hsa-miR-4538	CLIP-seq
MIRT2600428	hsa-miR-4641	CLIP-seq
MIRT2600429	hsa-miR-4650-5p	CLIP-seq
MIRT2600430	hsa-miR-4668-3p	CLIP-seq
MIRT2303715	hsa-miR-4677-3p	CLIP-seq
MIRT2303717	hsa-miR-4679	CLIP-seq
MIRT2600431	hsa-miR-4684-3p	CLIP-seq
MIRT2600432	hsa-miR-4686	CLIP-seq
MIRT2600433	hsa-miR-4687-3p	CLIP-seq
MIRT2600434	hsa-miR-4698	CLIP-seq
MIRT2600435	hsa-miR-4701-5p	CLIP-seq
MIRT2600436	hsa-miR-4708-3p	CLIP-seq
MIRT2600437	hsa-miR-4716-5p	CLIP-seq
MIRT2077196	hsa-miR-4720-5p	CLIP-seq
MIRT1262006	hsa-miR-4726-3p	CLIP-seq
MIRT1262007	hsa-miR-4738-3p	CLIP-seq
MIRT1262010	hsa-miR-4768-3p	CLIP-seq
MIRT1262011	hsa-miR-4775	CLIP-seq
MIRT2600438	hsa-miR-4777-5p	CLIP-seq
MIRT2600439	hsa-miR-4781-3p	CLIP-seq
MIRT2303723	hsa-miR-4795-3p	CLIP-seq
MIRT2077197	hsa-miR-4799-3p	CLIP-seq
MIRT2600440	hsa-miR-484	CLIP-seq
MIRT2600441	hsa-miR-5095	CLIP-seq
MIRT2600442	hsa-miR-5096	CLIP-seq
MIRT2600443	hsa-miR-518a-5p	CLIP-seq
MIRT2600444	hsa-miR-518d-5p	CLIP-seq
MIRT2600445	hsa-miR-519b-5p	CLIP-seq
MIRT2600446	hsa-miR-519c-5p	CLIP-seq
MIRT2600447	hsa-miR-520c-5p	CLIP-seq
MIRT2600448	hsa-miR-526a	CLIP-seq
MIRT2600449	hsa-miR-527	CLIP-seq
MIRT2600450	hsa-miR-543	CLIP-seq
MIRT1262019	hsa-miR-548ae	CLIP-seq
MIRT1262022	hsa-miR-548aj	CLIP-seq
MIRT1262023	hsa-miR-548am	CLIP-seq
MIRT2600451	hsa-miR-548s	CLIP-seq
MIRT1262025	hsa-miR-548x	CLIP-seq
MIRT1262027	hsa-miR-579	CLIP-seq
MIRT2600452	hsa-miR-588	CLIP-seq
MIRT2600453	hsa-miR-590-3p	CLIP-seq
MIRT2600454	hsa-miR-618	CLIP-seq
MIRT2600455	hsa-miR-622	CLIP-seq
MIRT1262033	hsa-miR-642b	CLIP-seq
MIRT2600456	hsa-miR-655	CLIP-seq
MIRT1262038	hsa-miR-92a	CLIP-seq
MIRT1262039	hsa-miR-92b	CLIP-seq
MIRT2303737	hsa-miR-98	CLIP-seq
MIRT1261931	hsa-miR-1208	CLIP-seq
MIRT2600384	hsa-miR-1256	CLIP-seq
MIRT1261933	hsa-miR-1267	CLIP-seq
MIRT2600385	hsa-miR-139-5p	CLIP-seq
MIRT1261945	hsa-miR-1915	CLIP-seq
MIRT2600387	hsa-miR-197	CLIP-seq
MIRT739557	hsa-miR-203	CLIP-seq
MIRT1261948	hsa-miR-216b	CLIP-seq
MIRT2600389	hsa-miR-30a	CLIP-seq
MIRT2600390	hsa-miR-30b	CLIP-seq
MIRT2600391	hsa-miR-30c	CLIP-seq
MIRT2600392	hsa-miR-30d	CLIP-seq
MIRT2600393	hsa-miR-30e	CLIP-seq
MIRT2303692	hsa-miR-3143	CLIP-seq
MIRT2600399	hsa-miR-3187-3p	CLIP-seq
MIRT2600400	hsa-miR-3199	CLIP-seq
MIRT1261968	hsa-miR-335	CLIP-seq
MIRT2600404	hsa-miR-34a	CLIP-seq
MIRT1261969	hsa-miR-34c-3p	CLIP-seq
MIRT2600405	hsa-miR-34c-5p	CLIP-seq
MIRT1261975	hsa-miR-3622b-5p	CLIP-seq
MIRT2600407	hsa-miR-3663-5p	CLIP-seq
MIRT2600409	hsa-miR-374c	CLIP-seq
MIRT2600411	hsa-miR-411	CLIP-seq
MIRT2600412	hsa-miR-4293	CLIP-seq
MIRT2600413	hsa-miR-4305	CLIP-seq
MIRT2600414	hsa-miR-4320	CLIP-seq
MIRT2600415	hsa-miR-4327	CLIP-seq
MIRT2600417	hsa-miR-4435	CLIP-seq
MIRT2600418	hsa-miR-4438	CLIP-seq
MIRT2600419	hsa-miR-4453	CLIP-seq
MIRT2600420	hsa-miR-4463	CLIP-seq
MIRT2600422	hsa-miR-4475	CLIP-seq
MIRT2600423	hsa-miR-4477b	CLIP-seq
MIRT2600424	hsa-miR-4494	CLIP-seq
MIRT2600425	hsa-miR-449a	CLIP-seq
MIRT2600426	hsa-miR-449b	CLIP-seq
MIRT2600427	hsa-miR-4538	CLIP-seq
MIRT2600429	hsa-miR-4650-5p	CLIP-seq
MIRT2303717	hsa-miR-4679	CLIP-seq
MIRT2600435	hsa-miR-4701-5p	CLIP-seq
MIRT2600436	hsa-miR-4708-3p	CLIP-seq
MIRT2600437	hsa-miR-4716-5p	CLIP-seq
MIRT2077196	hsa-miR-4720-5p	CLIP-seq
MIRT1262006	hsa-miR-4726-3p	CLIP-seq
MIRT1262007	hsa-miR-4738-3p	CLIP-seq
MIRT1262011	hsa-miR-4775	CLIP-seq
MIRT2600438	hsa-miR-4777-5p	CLIP-seq
MIRT2600439	hsa-miR-4781-3p	CLIP-seq
MIRT2303723	hsa-miR-4795-3p	CLIP-seq
MIRT2077197	hsa-miR-4799-3p	CLIP-seq
MIRT2600441	hsa-miR-5095	CLIP-seq
MIRT2600442	hsa-miR-5096	CLIP-seq
MIRT2600443	hsa-miR-518a-5p	CLIP-seq
MIRT2600444	hsa-miR-518d-5p	CLIP-seq
MIRT2600445	hsa-miR-519b-5p	CLIP-seq
MIRT2600446	hsa-miR-519c-5p	CLIP-seq
MIRT2600447	hsa-miR-520c-5p	CLIP-seq
MIRT2600448	hsa-miR-526a	CLIP-seq
MIRT2600449	hsa-miR-527	CLIP-seq
MIRT2600450	hsa-miR-543	CLIP-seq
MIRT1262024	hsa-miR-548c-3p	CLIP-seq
MIRT2688587	hsa-miR-548g	CLIP-seq
MIRT2303733	hsa-miR-548m	CLIP-seq
MIRT2600451	hsa-miR-548s	CLIP-seq
MIRT1262027	hsa-miR-579	CLIP-seq
MIRT2600452	hsa-miR-588	CLIP-seq
MIRT2600453	hsa-miR-590-3p	CLIP-seq
MIRT2600454	hsa-miR-618	CLIP-seq
MIRT2600455	hsa-miR-622	CLIP-seq
MIRT1262033	hsa-miR-642b	CLIP-seq
MIRT2600456	hsa-miR-655	CLIP-seq

138

Show/Hide all (138)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0002181	Process	Cytoplasmic translation	IDA	8706699, 34314702
GO:0003682	Function	Chromatin binding	IEA
GO:0003682	Function	Chromatin binding	ISS
GO:0004672	Function	Protein kinase activity	IEA
GO:0004672	Function	Protein kinase activity	TAS	7959015
GO:0004674	Function	Protein serine/threonine kinase activity	IBA
GO:0004674	Function	Protein serine/threonine kinase activity	IDA	18439900, 28552616, 32029622, 34077757, 36732624, 37079666
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	ISS
GO:0004674	Function	Protein serine/threonine kinase activity	TAS
GO:0004679	Function	AMP-activated protein kinase activity	IDA	14651849, 18439900, 24563466, 36732624, 37541260
GO:0004679	Function	AMP-activated protein kinase activity	IEA
GO:0004679	Function	AMP-activated protein kinase activity	ISS
GO:0004679	Function	AMP-activated protein kinase activity	TAS
GO:0004712	Function	Protein serine/threonine/tyrosine kinase activity	IDA	22797923
GO:0005515	Function	Protein binding	IPI	18439900, 19274086, 20562859, 20801214, 21072212, 21516116, 24722188, 25241761, 25416956, 28514442, 28552616, 28561066, 29892012, 30886144, 31515488, 32296183, 32707033, 32814053, 33961781, 35512704, 36931259
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	9693118
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	TAS	21768291
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005794	Component	Golgi apparatus	IDA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0006325	Process	Chromatin organization	IEA
GO:0006338	Process	Chromatin remodeling	IEA
GO:0006629	Process	Lipid metabolic process	IEA
GO:0006631	Process	Fatty acid metabolic process	IEA
GO:0006633	Process	Fatty acid biosynthetic process	IEA
GO:0006646	Process	Phosphatidylethanolamine biosynthetic process	IDA	19915674
GO:0006656	Process	Phosphatidylcholine biosynthetic process	IDA	34077757
GO:0006694	Process	Steroid biosynthetic process	IEA
GO:0006695	Process	Cholesterol biosynthetic process	IEA
GO:0006914	Process	Autophagy	IEA
GO:0007165	Process	Signal transduction	TAS	7959015
GO:0008202	Process	Steroid metabolic process	IEA
GO:0008203	Process	Cholesterol metabolic process	IEA
GO:0008610	Process	Lipid biosynthetic process	IEA
GO:0008610	Process	Lipid biosynthetic process	ISS
GO:0009267	Process	Cellular response to starvation	IDA	24529379
GO:0010468	Process	Regulation of gene expression	IEA
GO:0010494	Component	Cytoplasmic stress granule	IEA
GO:0010494	Component	Cytoplasmic stress granule	ISS
GO:0010508	Process	Positive regulation of autophagy	IBA
GO:0010508	Process	Positive regulation of autophagy	IEA
GO:0010508	Process	Positive regulation of autophagy	ISS
GO:0010629	Process	Negative regulation of gene expression	IEA
GO:0010629	Process	Negative regulation of gene expression	ISS
GO:0014850	Process	Response to muscle activity	IEA
GO:0016055	Process	Wnt signaling pathway	IEA
GO:0016126	Process	Sterol biosynthetic process	IEA
GO:0016239	Process	Positive regulation of macroautophagy	TAS	25126726
GO:0016241	Process	Regulation of macroautophagy	IEA
GO:0016241	Process	Regulation of macroautophagy	ISS
GO:0016301	Function	Kinase activity	IEA
GO:0016607	Component	Nuclear speck	IDA
GO:0016607	Component	Nuclear speck	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0030424	Component	Axon	IEA
GO:0030424	Component	Axon	ISS
GO:0030425	Component	Dendrite	IEA
GO:0030425	Component	Dendrite	ISS
GO:0031588	Component	Nucleotide-activated protein kinase complex	IBA
GO:0031588	Component	Nucleotide-activated protein kinase complex	IEA
GO:0031588	Component	Nucleotide-activated protein kinase complex	IPI	9693118, 25412657, 29657085
GO:0031588	Component	Nucleotide-activated protein kinase complex	ISS
GO:0031669	Process	Cellular response to nutrient levels	IDA	12747827, 29236692, 29750193, 31601708, 31601764, 36528027
GO:0031669	Process	Cellular response to nutrient levels	IDA	25412657
GO:0031669	Process	Cellular response to nutrient levels	IEA
GO:0031669	Process	Cellular response to nutrient levels	ISS
GO:0031669	Process	Cellular response to nutrient levels	NAS	9693118, 29657085
GO:0032007	Process	Negative regulation of TOR signaling	IEA
GO:0032007	Process	Negative regulation of TOR signaling	ISS
GO:0034198	Process	Cellular response to amino acid starvation	IDA	35338845
GO:0034599	Process	Cellular response to oxidative stress	IEA
GO:0034599	Process	Cellular response to oxidative stress	ISS
GO:0036064	Component	Ciliary basal body	IDA
GO:0036064	Component	Ciliary basal body	IEA
GO:0038202	Process	TORC1 signaling	IDA	12087098, 12747827, 29750193
GO:0042149	Process	Cellular response to glucose starvation	IBA
GO:0042149	Process	Cellular response to glucose starvation	IDA	18439900
GO:0042149	Process	Cellular response to glucose starvation	IDA	14651849, 18439900, 34077757, 36732624
GO:0042149	Process	Cellular response to glucose starvation	IEA
GO:0042593	Process	Glucose homeostasis	IEA
GO:0042593	Process	Glucose homeostasis	ISS
GO:0042752	Process	Regulation of circadian rhythm	IEA
GO:0042752	Process	Regulation of circadian rhythm	ISS
GO:0043025	Component	Neuronal cell body	IEA
GO:0043025	Component	Neuronal cell body	ISS
GO:0043066	Process	Negative regulation of apoptotic process	IEA
GO:0043066	Process	Negative regulation of apoptotic process	ISS
GO:0045821	Process	Positive regulation of glycolytic process	ISS
GO:0045947	Process	Negative regulation of translational initiation	IDA	22578813
GO:0045948	Process	Positive regulation of translational initiation	IDA	1922062, 29750193
GO:0046872	Function	Metal ion binding	IEA
GO:0047322	Function	[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity	IEA
GO:0048511	Process	Rhythmic process	IEA
GO:0055089	Process	Fatty acid homeostasis	ISS
GO:0055089	Process	Fatty acid homeostasis	TAS
GO:0061462	Process	Protein localization to lysosome	IDA	31601708
GO:0062028	Process	Regulation of stress granule assembly	IEA
GO:0070507	Process	Regulation of microtubule cytoskeleton organization	IEA
GO:0070507	Process	Regulation of microtubule cytoskeleton organization	ISS
GO:0071277	Process	Cellular response to calcium ion	IEA
GO:0071277	Process	Cellular response to calcium ion	ISS
GO:0071333	Process	Cellular response to glucose stimulus	IEA
GO:0071333	Process	Cellular response to glucose stimulus	ISS
GO:0071380	Process	Cellular response to prostaglandin E stimulus	IEA
GO:0071466	Process	Cellular response to xenobiotic stimulus	IEA
GO:0085020	Process	Protein K6-linked ubiquitination	IDA	36528027
GO:0090200	Process	Positive regulation of release of cytochrome c from mitochondria	IDA	32029622
GO:0097009	Process	Energy homeostasis	ISS
GO:0097284	Process	Hepatocyte apoptotic process	IDA	32029622
GO:0106310	Function	Protein serine kinase activity	IEA
GO:0140823	Function	Histone H2BS36 kinase activity	IEA
GO:0140823	Function	Histone H2BS36 kinase activity	ISS
GO:1903829	Process	Positive regulation of protein localization	IEA
GO:1903829	Process	Positive regulation of protein localization	ISS
GO:1903944	Process	Negative regulation of hepatocyte apoptotic process	IDA	32029622
GO:1903944	Process	Negative regulation of hepatocyte apoptotic process	IEA
GO:1904262	Process	Negative regulation of TORC1 signaling	IBA
GO:1904262	Process	Negative regulation of TORC1 signaling	IDA	9045618, 12906785, 30651352, 35338845
GO:1904262	Process	Negative regulation of TORC1 signaling	IDA	14651849, 18439900, 36732624, 37079666
GO:1904262	Process	Negative regulation of TORC1 signaling	IEA
GO:1904263	Process	Positive regulation of TORC1 signaling	IDA	29236692, 31601708, 31601764, 36528027, 37541260
GO:1904428	Process	Negative regulation of tubulin deacetylation	IEA
GO:1904428	Process	Negative regulation of tubulin deacetylation	ISS
GO:1905691	Process	Lipid droplet disassembly	IDA	34077757
GO:1905691	Process	Lipid droplet disassembly	IEA
GO:1990044	Process	Protein localization to lipid droplet	IBA
GO:1990044	Process	Protein localization to lipid droplet	IDA	34077757
GO:1990044	Process	Protein localization to lipid droplet	IEA

MIM	HGNC	e!Ensembl
600497	9377	ENSG00000162409

P54646

Protein name

5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31)

Protein function

Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism (PubMed:17307971, PubMed:17712357). In response to reduction of intracellular ATP levels, AM

PDB

2H6D , 2LTU , 2YZA , 3AQV , 4CFE , 4CFF , 4ZHX , 5EZV , 5ISO , 6B1U , 6B2E , 6BX6 , 7MYJ , 8BIK

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00069	Pkinase	16 → 268	Protein kinase domain	Domain
PF16579	AdenylateSensor	401 → 495	Adenylate sensor of SNF1-like protein kinase	Domain

Sequence

MAEKQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGK
IKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLF
QQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYA
APEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS
VATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKF
ECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPSGSFMDDSAMHIP
PGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVY
RAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQR
SGSSTPQRSCSAAGLHRPRSSFDSTTAESHSLSGSLTGSLTGSTLSSVSPRLGSHTMDFF
EMCASLITTLAR

Sequence length

552

Interactions

View interactions

	KEGG		Reactome
	FoxO signaling pathway Autophagy - animal mTOR signaling pathway PI3K-Akt signaling pathway AMPK signaling pathway Longevity regulating pathway Longevity regulating pathway - multiple species Apelin signaling pathway Tight junction Circadian rhythm Thermogenesis Insulin signaling pathway Adipocytokine signaling pathway Oxytocin signaling pathway Glucagon signaling pathway Insulin resistance Non-alcoholic fatty liver disease Alcoholic liver disease Hypertrophic cardiomyopathy Fluid shear stress and atherosclerosis		Macroautophagy AMPK inhibits chREBP transcriptional activation activity Carnitine metabolism Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Regulation of TP53 Activity through Phosphorylation

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
High myopia	Uncertain significance	rs145987132	RCV000785689
PRKAA2-related disorder	Likely benign; Benign	rs140986085, rs534372739, rs369893630, rs55717918, rs41285004, rs112086177	RCV003964094 RCV003914561 RCV003934132 RCV003979028 RCV003916017 RCV003923053

Show/Hide Text Mining Associations (127)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Adenocarcinoma	Associate	25798539
Adenoma Oxyphilic	Stimulate	26655904
Adenosine monophosphate deaminase deficiency	Associate	15766830
Alzheimer Disease	Associate	33942972
Amyotrophic Lateral Sclerosis	Associate	28213588
Arrhythmias Cardiac	Associate	12747836
Arthritis Rheumatoid	Associate	30100905, 36661308
Breast Neoplasms	Associate	19723334, 24406729, 25427448, 25651975, 26752181, 26919657, 27145268, 29702405, 31507133, 31907353, 35864962, 37542585, 39512680, 40427554
Carcinogenesis	Associate	25017332
Carcinoma Basal Cell	Associate	27367504
Carcinoma Endometrioid	Associate	22897928
Carcinoma Hepatocellular	Associate	21418191, 22728651, 25017332, 26252753, 26986101, 28338175, 29246230, 29991055, 30311444, 31427562, 32323845, 32626741, 34638959, 34790050, 35592706
Carcinoma Hepatocellular	Inhibit	30809021
Carcinoma Non Small Cell Lung	Associate	25629933, 26847819, 27279498, 28945763, 30977310, 31389598, 35419253, 35745143, 36281945
Carcinoma Non Small Cell Lung	Stimulate	37584455
Carcinoma Renal Cell	Associate	27705920, 35633317, 36750850
Cardiomyopathies	Inhibit	32460327
Cardiomyopathy Hypertrophic	Associate	15766830
Cardiovascular Diseases	Associate	32733639
Chemical and Drug Induced Liver Injury	Associate	22754327
Cholangiocarcinoma	Associate	31085159
Cholelithiasis	Associate	33279689, 33893772
Cholestasis Intrahepatic	Inhibit	33893772
Chondrosarcoma	Associate	24047437
Colorectal Neoplasms	Associate	22975518, 25833196, 25854428, 26919111, 29491475, 31485623, 31648230, 31888414, 36806702, 36950803, 38149567
Corneal Endothelial Cell Loss	Associate	30942428
Cystic Fibrosis	Associate	23264659
Diabetes Gestational	Associate	28125642
Diabetes Mellitus	Associate	25595658, 35864962, 36360783, 38354757
Diabetes Mellitus Type 2	Associate	21931634, 31993556, 32337289, 34589546
Disease	Associate	15766830
Drug Related Side Effects and Adverse Reactions	Associate	26252753, 30015901, 30866453
Endometrial Neoplasms	Associate	26135947, 33577023, 34170849, 37082998
Esophageal Squamous Cell Carcinoma	Associate	35463992
Fabry Disease	Associate	27938475
Fahr's disease	Associate	35713844
Fatigue	Associate	37542585
Fatigue Syndrome Chronic	Associate	25836975
Femur Head Necrosis	Associate	27911275
Fetal Macrosomia	Associate	28125642
Fibrosis	Inhibit	36555150
Gallbladder Diseases	Inhibit	33893772
Gallstones	Associate	33279689
Gardner Syndrome	Associate	27444220
Geographic Atrophy	Associate	18195011
Gilbert Disease	Associate	27444220
Glioblastoma	Associate	20880848, 24607408, 38098117
Glioma	Associate	27532105
Glucose Intolerance	Stimulate	21931634
Glucose Intolerance	Inhibit	40378953
Glycogen Storage Disease	Associate	32259713
Graves Ophthalmopathy	Inhibit	36555150
Head and Neck Neoplasms	Associate	33274210
Heart Diseases	Associate	32460327
Heart Failure	Associate	32259713, 32460327
Hematologic Neoplasms	Inhibit	25846811
Hemolytic Uremic Syndrome	Stimulate	25049200
Hyperglycemia	Associate	36806702
Hypertension	Associate	36297114
Hypertension Pulmonary	Associate	32914566
hypoglycemic encephalopathy	Associate	29494709
Hypoxia	Associate	18359290, 35523819
Inclusion Body Myopathy 3 Autosomal Dominant	Associate	15766830
Inflammation	Inhibit	16361706
Inflammation	Associate	23264659, 24669186, 29394526, 30100905, 31232696, 35603508, 36555150, 37584301, 37895018
Insulin Resistance	Associate	15371448, 26001396, 28183786, 33509040
Insulin Resistance	Inhibit	22323564
Kidney Failure Chronic	Associate	25049200
Kidney Neoplasms	Associate	36246395
Lafora Disease	Associate	21728993
Leukemia Lymphocytic Chronic B Cell	Associate	12522004
Leukemia Myelogenous Chronic BCR ABL Positive	Associate	25041018
Leukemia Myeloid Acute	Associate	25846811
Leukemia Myeloid Acute	Inhibit	36148953
Liver Diseases	Associate	23510538
Lung Neoplasms	Associate	21258249, 25798539, 30157903, 32198390, 36281945
Lung Neoplasms	Inhibit	36872368
Lupus Erythematosus Systemic	Associate	29755474
Lupus Erythematosus Systemic	Stimulate	36815949
Lymphoma Large B Cell Diffuse	Associate	23396962
Lymphoma Non Hodgkin	Associate	23396962
Melanoma	Associate	25846811
Metabolic Diseases	Associate	23510538, 29394526, 29480475
Metabolic Syndrome	Associate	37904219
Mitochondrial Diseases	Associate	23536703, 31480724, 33066427
Muscular Atrophy	Associate	29364489
Muscular Dystrophy Emery Dreifuss	Associate	23258787
Nasal Polyps	Associate	34653793
Nasopharyngeal Carcinoma	Associate	25872765
Neoplasm Metastasis	Associate	29577356, 36658117
Neoplasms	Associate	12409306, 19221486, 19293639, 21042412, 21159649, 22897928, 24553147, 24916949, 25629604, 25651975, 25846811, 25849721, 26001218, 26986101, 27141100 View all (22 more)
Neoplasms	Inhibit	21258249, 22029423, 22728651, 26337566, 26892736, 36658117, 36872368
Neoplasms	Stimulate	35592706
Neurodegenerative Diseases	Associate	33036367
Neurotoxicity Syndromes	Associate	32377295
Non alcoholic Fatty Liver Disease	Associate	30957185, 35406631
Obesity	Inhibit	22323564, 27481183
Obesity	Associate	22990076, 27444220, 32152146, 36806702
Obesity Maternal	Inhibit	29093265
Osteoporosis	Associate	30013450
Ovarian Diseases	Associate	22897928
Ovarian Neoplasms	Associate	22897928, 25491408, 26261517, 29620187, 32312965, 36114703, 36308626
Overweight	Associate	22990076
Overweight	Inhibit	27481183
Pancreatic Neoplasms	Associate	30323244, 30365057, 31904416, 32345326, 33650657, 36284209
Parkinson Disease	Associate	29115479
Polycystic Ovary Syndrome	Associate	26373822
Pre Eclampsia	Associate	38166707
Prostatic Neoplasms	Associate	26447757, 27248322, 28876465, 29577356, 32931739, 34309216
Prostatic Neoplasms Castration Resistant	Associate	27248322
Prostatitis	Associate	31395901
Pulmonary Disease Chronic Obstructive	Associate	23258787
Reperfusion Injury	Associate	37253410
Rhabdomyosarcoma	Associate	29620138, 34205996
Squamous Cell Carcinoma of Head and Neck	Associate	24769813, 33526991, 36505439
Stomach Neoplasms	Associate	25756516, 26919111, 28052040, 28423719, 30015846, 30720062, 32227453, 33538080, 35075806
Syndrome	Associate	32259713
Thymoma	Associate	36916520
Thyroid Cancer Papillary	Associate	26617795, 30575918, 32964981
Triple Negative Breast Neoplasms	Associate	27145268
Tuberculosis	Associate	25996154
Tuberculosis Pulmonary	Associate	25996154
Tyrosine Kinase 2 Deficiency	Associate	34635505
Uterine Cervical Neoplasms	Associate	26337566, 28230778, 33236135, 36658117
Uveal melanoma	Associate	24781943, 37647867
Weight Gain	Associate	25740917
Wolff Parkinson White Syndrome	Associate	15766830

PRKAA2 (protein kinase AMP-activated catalytic subunit alpha 2)