Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
55625
Gene name Gene Name - the full gene name approved by the HGNC.
ZDHHC palmitoyltransferase 7
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ZDHHC7
Synonyms (NCBI Gene) Gene synonyms aliases
DHHC7, SERZ-B, SERZ1, ZNF370
Chromosome Chromosome number
16
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
16q24.1
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT028769 hsa-miR-26b-5p Microarray 19088304
MIRT039953 hsa-miR-615-3p CLASH 23622248
MIRT037109 hsa-miR-877-3p CLASH 23622248
MIRT037109 hsa-miR-877-3p CLASH 23622248
MIRT036367 hsa-miR-1229-3p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane IEA
GO:0005654 Component Nucleoplasm IDA
GO:0005783 Component Endoplasmic reticulum IBA 21873635
GO:0005794 Component Golgi apparatus IBA 21873635
GO:0005794 Component Golgi apparatus IDA 16647879, 22031296
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
614604 18459 ENSG00000153786
Protein
UniProt ID Q9NXF8
Protein name Palmitoyltransferase ZDHHC7 (EC 2.3.1.225) (Acyltransferase ZDHHC7) (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 7) (DHHC-7)
Protein function Golgi-localized palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates and therefore functions in several unrelated biological processes (PubMed:22031296, PubMed:27380321, PubMed:28196865). Has no stringent
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01529 DHHC 129 258 DHHC palmitoyltransferase Family
Sequence
MQPSGHRLRDVEHHPLLAENDNYDSSSSSSSEADVADRVWFIRDGCGMICAVMTWLLVAY
ADFVVTFVMLLPSKDFWYSVVNGVIFNCLAVLALSSHLRTMLTDPGAVPKGNATKEYMES
LQLKPGEVIYKCPKCCCIKPERAHHCSICKRCIRKMDHHCPWVNNCVGEKNQRFFVLFTM
YIALSSVHALILCGFQFISCVRGQWTECSDFSPPITVILLIFLCLEGLLFFTFTAVMFGT
QIHSICNDETEIERLKSE
KPTWERRLRWEGMKSVFGGPPSLLWMNPFVGFRFRRLPTRPR
KGGPEFSV
Sequence length 308
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Extra-nuclear estrogen signaling
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Colorectal cancer Colorectal Carcinoma rs137854568, rs137854573, rs137854575, rs387906234, rs121908380, rs121908702, rs267606674, rs794729661, rs121909055, rs281865417, rs267606884, rs28934575, rs587776769, rs104893815, rs587776800
View all (467 more)
Unknown
Disease term Disease name Evidence References Source
Breast Cancer Breast Cancer Importantly, breast cancer patients bearing PRC2 LOF mutations displayed significantly worse prognosis compared with PRC2 wild-type patients GWAS, CBGDA
Prostate cancer Prostate cancer Together, these results show that PRRX2 is an oncogene and might play a role in the aggressiveness of PC within the DNPC population. GWAS, CBGDA
Associations from Text Mining
Disease Name Relationship Type References
Carcinogenesis Associate 37978524
Cerebral Infarction Associate 31781304