Gene Gene information from NCBI Gene database.
Entrez ID 55609
Gene name Zinc finger protein 280C
Gene symbol ZNF280C
Synonyms (NCBI Gene)
SUHW3ZNF633ZPET
Chromosome X
Chromosome location Xq26.1
Summary This gene encodes a member of the zinc finger domain-containing protein family. This family member contains multiple Cys2-His2(C2H2)-type zinc finger domains, the most common type of zinc finger domain that self-folds to form a beta-beta-alpha structure t
miRNA miRNA information provided by mirtarbase database.
300
miRTarBase ID miRNA Experiments Reference
MIRT023917 hsa-miR-1-3p Microarray 18668037
MIRT051185 hsa-miR-16-5p CLASH 23622248
MIRT044863 hsa-miR-195-5p CLASH 23622248
MIRT039402 hsa-miR-421 CLASH 23622248
MIRT636083 hsa-miR-383-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
9
GO ID Ontology Definition Evidence Reference
GO:0000978 Function RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0003677 Function DNA binding IEA
GO:0005515 Function Protein binding IPI 27705803, 32296183, 33961781, 35271311
GO:0005634 Component Nucleus IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8ND82
Protein name Zinc finger protein 280C (Suppressor of hairy wing homolog 3) (Zinc finger protein 633)
Protein function May function as a transcription factor.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13836 DUF4195 46 227 Domain of unknown function (DUF4195) Domain
Sequence
MDDDKPFQPKNISKMAELFMECEEEELEPWQKKVEETQDEDDDELIFVGEISSSKPAISN
ILNRGHSSSSSKGIKSEPHSPGIPEIFRTASQRCRDPPSNPVAASPRFHLVSKSSQSSVT
VENASKPDFTKNSQVGSDNSSILLFDSTQESLPPSQDIPAIFREGMKNTSYVLKHPSTSK
VNSVTPKKPKTSEDVPQINPSTSLPLIGSPPVTSSQVMLSKGTNTSS
PYDAGADYLRACP
KCNVQFNLLDPLKYHMKHCCPDMITKFLGVIVKSERPCDEDKTDSETGKLIMLVNEFYYG
RHEGVTEKEPKTYTTFKCFSCSKVLKNNIRFMNHMKHHLELEKQNNESWENHTTCQHCYR
QYPTPFQLQCHIESTHTPHEFSTICKICELSFETEHILLQHMKDTHKPGEMPYVCQVCQF
RSSTFSDVEAHFRAAHENTKNLLCPFCLKVSKMATPYMNHYMKHQKKGVHRCPKCRLQFL
TSKEKAEHKAQHRTFIKPKELEGLPPGAKVTIRASLGPLQSKLPTAPFGCAPGTSFLQVT
PPTSQNTTARNPRKSNASRSKTSKLHATTSTASKVNTSKPRGRIAKSKAKPSYKQKRQRN
RKNKMSLALKNIRCRRGIHKCIECHSKIKDFASHFSIYIHCSFCKYNTNCNKAFVNHMMS
SHSNHPGKRFCIFKKHSGTLRGITLVCLKCDFLADSSGLDRMAKHLSQRKTHTCQVIIEN
VSKSTSTSEPTTGCSLK
Sequence length 737
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ALZHEIMER DISEASE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Carcinogenesis Associate 35605119
★☆☆☆☆
Found in Text Mining only
Cell Transformation Neoplastic Associate 35605119
★☆☆☆☆
Found in Text Mining only
Colitis Associate 35605119
★☆☆☆☆
Found in Text Mining only
Colorectal Neoplasms Associate 35605119
★☆☆☆☆
Found in Text Mining only
Neoplasm Metastasis Stimulate 35605119
★☆☆☆☆
Found in Text Mining only
Neoplasms Inhibit 35605119
★☆☆☆☆
Found in Text Mining only