GALNT10 (polypeptide N-acetylgalactosaminyltransferase 10)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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55568 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Polypeptide N-acetylgalactosaminyltransferase 10 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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GALNT10 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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GALNACT10, PPGALNACT10, PPGANTASE10 |
Chromosome
Chromosome number
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5 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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5q33.2 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the GalNAc polypeptide N-acetylgalactosaminyltransferases. These enzymes catalyze the first step in the synthesis of mucin-type oligosaccharides. These proteins transfer GalNAc from UDP-GalNAc to either serine or threonine re |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||
UniProt ID | Q86SR1 | |||||||||||||||
Protein name | Polypeptide N-acetylgalactosaminyltransferase 10 (EC 2.4.1.41) (Polypeptide GalNAc transferase 10) (GalNAc-T10) (pp-GaNTase 10) (Protein-UDP acetylgalactosaminyltransferase 10) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10) | |||||||||||||||
Protein function | Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward Muc5Ac and EA2 peptide substrates. | |||||||||||||||
PDB | 2D7I , 2D7R | |||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Widely expressed. Expressed at high level in small intestine, and at intermediate levels in stomach, pancreas, ovary, thyroid gland and spleen. Weakly expressed in other tissues. {ECO:0000269|PubMed:12417297}. | |||||||||||||||
Sequence |
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Sequence length | 603 | |||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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