CDCA7L (cell division cycle associated 7 like)

Gene

• Entrez ID: 55536
• Gene name: Cell division cycle associated 7 like
• Gene symbol: CDCA7L
• Synonyms (NCBI Gene): JPO2, R1, RAM2
• Chromosome: 7
• Chromosome location: 7p15.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT019850	hsa-miR-375	Microarray	20215506
MIRT002722	hsa-miR-124-3p	Microarray	15685193
MIRT002722	hsa-miR-124-3p	Proteomics	18668037
MIRT041933	hsa-miR-484	CLASH	23622248
MIRT879064	hsa-miR-129-3p	CLIP-seq
MIRT879065	hsa-miR-3163	CLIP-seq
MIRT879066	hsa-miR-3613-3p	CLIP-seq
MIRT879067	hsa-miR-371b-5p	CLIP-seq
MIRT879068	hsa-miR-4687-5p	CLIP-seq
MIRT879069	hsa-miR-4698	CLIP-seq
MIRT879070	hsa-miR-499-3p	CLIP-seq
MIRT879071	hsa-miR-499a-3p	CLIP-seq
MIRT879072	hsa-miR-548k	CLIP-seq
MIRT879073	hsa-miR-548n	CLIP-seq
MIRT879074	hsa-miR-607	CLIP-seq
MIRT879075	hsa-miR-938	CLIP-seq
MIRT879076	hsa-miR-1238	CLIP-seq
MIRT879077	hsa-miR-1294	CLIP-seq
MIRT879078	hsa-miR-3198	CLIP-seq
MIRT879066	hsa-miR-3613-3p	CLIP-seq
MIRT879079	hsa-miR-3622a-5p	CLIP-seq
MIRT879080	hsa-miR-3652	CLIP-seq
MIRT879081	hsa-miR-371-5p	CLIP-seq
MIRT879067	hsa-miR-371b-5p	CLIP-seq
MIRT879082	hsa-miR-4309	CLIP-seq
MIRT879083	hsa-miR-431	CLIP-seq
MIRT879084	hsa-miR-4423-3p	CLIP-seq
MIRT879085	hsa-miR-4430	CLIP-seq
MIRT879086	hsa-miR-4505	CLIP-seq
MIRT879087	hsa-miR-4537	CLIP-seq
MIRT879088	hsa-miR-4652-3p	CLIP-seq
MIRT879089	hsa-miR-4710	CLIP-seq
MIRT879090	hsa-miR-4792	CLIP-seq
MIRT879070	hsa-miR-499-3p	CLIP-seq
MIRT879071	hsa-miR-499a-3p	CLIP-seq
MIRT879091	hsa-miR-548c-3p	CLIP-seq
MIRT879072	hsa-miR-548k	CLIP-seq
MIRT879073	hsa-miR-548n	CLIP-seq
MIRT879092	hsa-miR-586	CLIP-seq
MIRT879093	hsa-miR-767-5p	CLIP-seq
MIRT879094	hsa-miR-1285	CLIP-seq
MIRT879095	hsa-miR-1343	CLIP-seq
MIRT879096	hsa-miR-1470	CLIP-seq
MIRT879097	hsa-miR-3187-5p	CLIP-seq
MIRT879098	hsa-miR-4469	CLIP-seq
MIRT879099	hsa-miR-4667-3p	CLIP-seq
MIRT879100	hsa-miR-4793-3p	CLIP-seq
MIRT879101	hsa-miR-612	CLIP-seq
MIRT879093	hsa-miR-767-5p	CLIP-seq
MIRT1920351	hsa-miR-4501	CLIP-seq
MIRT879070	hsa-miR-499-3p	CLIP-seq
MIRT879071	hsa-miR-499a-3p	CLIP-seq
MIRT879072	hsa-miR-548k	CLIP-seq
MIRT879073	hsa-miR-548n	CLIP-seq
MIRT1920352	hsa-miR-548t	CLIP-seq
MIRT1920351	hsa-miR-4501	CLIP-seq
MIRT879070	hsa-miR-499-3p	CLIP-seq
MIRT879071	hsa-miR-499a-3p	CLIP-seq
MIRT879072	hsa-miR-548k	CLIP-seq
MIRT879073	hsa-miR-548n	CLIP-seq
MIRT1920352	hsa-miR-548t	CLIP-seq
MIRT1960590	hsa-miR-1185	CLIP-seq
MIRT1960591	hsa-miR-125a-3p	CLIP-seq
MIRT1960592	hsa-miR-139-5p	CLIP-seq
MIRT1960593	hsa-miR-15a	CLIP-seq
MIRT1960594	hsa-miR-15b	CLIP-seq
MIRT1960595	hsa-miR-16	CLIP-seq
MIRT1960596	hsa-miR-195	CLIP-seq
MIRT1960597	hsa-miR-214	CLIP-seq
MIRT1960598	hsa-miR-25	CLIP-seq
MIRT1960599	hsa-miR-302f	CLIP-seq
MIRT1960600	hsa-miR-32	CLIP-seq
MIRT1960601	hsa-miR-342-3p	CLIP-seq
MIRT1960602	hsa-miR-3605-5p	CLIP-seq
MIRT1960603	hsa-miR-3619-5p	CLIP-seq
MIRT1960604	hsa-miR-363	CLIP-seq
MIRT1960605	hsa-miR-367	CLIP-seq
MIRT1960606	hsa-miR-3679-5p	CLIP-seq
MIRT1960607	hsa-miR-424	CLIP-seq
MIRT1960608	hsa-miR-4325	CLIP-seq
MIRT1960609	hsa-miR-4690-5p	CLIP-seq
MIRT1960610	hsa-miR-4726-3p	CLIP-seq
MIRT1960611	hsa-miR-497	CLIP-seq
MIRT1960612	hsa-miR-548g	CLIP-seq
MIRT1960613	hsa-miR-582-5p	CLIP-seq
MIRT1960614	hsa-miR-761	CLIP-seq
MIRT1960615	hsa-miR-802	CLIP-seq
MIRT1960616	hsa-miR-92a	CLIP-seq
MIRT1960617	hsa-miR-92b	CLIP-seq
MIRT2500536	hsa-let-7a	CLIP-seq
MIRT2500537	hsa-let-7b	CLIP-seq
MIRT2500538	hsa-let-7c	CLIP-seq
MIRT2500539	hsa-let-7d	CLIP-seq
MIRT2500540	hsa-let-7e	CLIP-seq
MIRT2500541	hsa-let-7f	CLIP-seq
MIRT2500542	hsa-let-7g	CLIP-seq
MIRT2500543	hsa-let-7i	CLIP-seq
MIRT2500544	hsa-miR-122	CLIP-seq
MIRT2500545	hsa-miR-1251	CLIP-seq
MIRT2500546	hsa-miR-1256	CLIP-seq
MIRT2500547	hsa-miR-1287	CLIP-seq
MIRT2500548	hsa-miR-1305	CLIP-seq
MIRT2500549	hsa-miR-3135b	CLIP-seq
MIRT879066	hsa-miR-3613-3p	CLIP-seq
MIRT2500550	hsa-miR-362-5p	CLIP-seq
MIRT879081	hsa-miR-371-5p	CLIP-seq
MIRT879067	hsa-miR-371b-5p	CLIP-seq
MIRT2500551	hsa-miR-4432	CLIP-seq
MIRT2500552	hsa-miR-4458	CLIP-seq
MIRT2500553	hsa-miR-4500	CLIP-seq
MIRT2500554	hsa-miR-500b	CLIP-seq
MIRT2500555	hsa-miR-501-5p	CLIP-seq
MIRT2500556	hsa-miR-517b	CLIP-seq
MIRT879072	hsa-miR-548k	CLIP-seq
MIRT879073	hsa-miR-548n	CLIP-seq
MIRT2500557	hsa-miR-95	CLIP-seq
MIRT2500558	hsa-miR-98	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001650	Component	Fibrillar center	IDA
GO:0005515	Function	Protein binding	IPI	25082813, 25416956, 26871637, 28169274, 29892012, 29997176, 32296183
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005634	Component	Nucleus	IDA	15994933
GO:0005654	Component	Nucleoplasm	IDA
GO:0005730	Component	Nucleolus	IDA
GO:0005829	Component	Cytosol	IDA
GO:0006355	Process	Regulation of transcription, DNA-templated	IEA
GO:0008284	Process	Positive regulation of cell population proliferation	IDA	15994933

Other IDs

• MIM: 609685
• HGNC: 30777
• e!Ensembl: ENSG00000164649

Protein

• UniProt ID: Q96GN5
• Protein name: Cell division cycle-associated 7-like protein (Protein JPO2) (Transcription factor RAM2)
• Protein function: Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in med
• PDB: 5YI9, 6EMO
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF10497	zf-4CXXC_R1	345 → 443	Zinc-finger domain of monoamine-oxidase A repressor R1	Domain

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitous. Overexpressed in medulloblastoma. {ECO:0000269|PubMed:15654081, ECO:0000269|PubMed:15994933}.
• Sequence:

  MELATRYQIPKEVADIFNAPSDDEEFVGFRDDVPMETLSSEESCDSFDSLESGKQQDVRF
  HSKYFTEELRRIFIEDTDSETEDFAGFTQSDLNGKTNPEVMVVESDLSDDGKASLVSEEE
  EDEEEDKATPRRSRSRRSSIGLRVAFQFPTKKLANKPDKNSSSEQLFSSARLQNEKKTIL
  ERKKDCRQVIQREDSTSESEDDSRDESQESSDALLKRTMNIKENKAMLAQLLAELNSMPD
  FFPVRTPTSASRKKTVRRAFSEGQITRRMNPTRSARPPEKFALENFTVSAAKFAEEFYSF
  RRRKTIGGKCREYRRRHRISSFRPVEDITEEDLENVAITVRDKIYDKVLGNTCHQCRQKT
  IDTKTVCRNQGCCGVRGQFCGPCLRNRYGEDVRSALLDPDWVCPPCRGICNCSYCRKRDG
  RCATGILIHLAKFYGYDNVKEYLESLQKELVEDN

• Sequence length: 454

Associated diseases

Causal
Disease term	Disease name	dbSNP ID	References
Breast carcinoma	Breast Carcinoma	rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451, rs397507859, rs80359709, rs80359742, rs80359205, rs80357627, rs80357004, rs80357571, rs80357767, rs80357653, rs80358086, rs80357608, rs28897696, rs41293465, rs146650273, rs63751017, rs63750617, rs63750726, rs63750199, rs63749848, rs398122618, rs398122653, rs397509211, rs80357791, rs121912666, rs587778541, rs121908698, rs536907995, rs587781302, rs140342925, rs587781506, rs587782652, rs587782849, rs587783057, rs139770721, rs374950566, rs786202800, rs863224451, rs377153250, rs747727055, rs876658804, rs780001540, rs760815829, rs878854926, rs775248597, rs886040658, rs886040192, rs786203523, rs886040319, rs397508006, rs587782011, rs1060502772, rs1555461727, rs1553333072, rs1114167702, rs1257401983, rs886040950, rs1060502759, rs774684620, rs142947311, rs1555580883, rs748513310, rs376170600, rs863224499, rs1593909229, rs748453607, rs1294578913, rs1574737047, rs1593909960, rs2081922847, rs2082559544, rs2053694038	29059683
Ciliary dyskinesia	Ciliary Motility Disorders, CILIARY DYSKINESIA, PRIMARY, 7 (disorder)	rs397515339, rs267607225, rs267607226, rs786205052, rs267607227, rs118204041, rs118204042, rs118204043, rs137853191, rs121434369, rs397515565, rs397515358, rs137852998, rs397515363, rs79833450, rs121908854, rs121908855, rs1554294478, rs79967166, rs121908853, rs1580543863, rs62642057, rs62638634, rs137852549, rs606231180, rs606231181, rs387907021, rs397515392, rs397515393, rs387907092, rs387907093, rs387907151, rs387907152, rs397515395, rs587776910, rs145457535, rs368260932, rs147718607, rs606231238, rs606231239, rs201133219, rs606231240, rs672601333, rs751785066, rs397514561, rs397515413, rs397515414, rs397515424, rs141945265, rs397515425, rs200321595, rs312262868, rs587776997, rs142371860, rs373501414, rs397515540, rs397515541, rs397515563, rs587778819, rs587778820, rs587778821, rs587778822, rs138815960, rs587777043, rs587777044, rs397515460, rs587777045, rs200913791, rs397515461, rs587777047, rs587777048, rs587777049, rs138320978, rs587777058, rs587777059, rs151107532, rs397518455, rs397518456, rs397515340, rs397515488, rs397515621, rs397515622, rs397518458, rs201740530, rs886037653, rs863223325, rs143740376, rs398122401, rs869320683, rs398122960, rs369037463, rs398123336, rs281865301, rs62635001, rs62635002, rs62653029, rs281865304, rs281865296, rs62635010, rs62635009, rs62635011, rs62635013, rs62650215, rs62638627, rs62638626, rs62638639, rs62638642, rs281865297, rs62650216, rs62638652, rs62638655, rs62640586, rs62640588, rs62640592, rs281865295, rs587777199, rs587777498, rs587777499, rs587777500, rs587777501, rs587777502, rs587777503, rs587777635, rs587777780, rs727502975, rs727502971, rs727504802, rs727502977, rs727504815, rs727503394, rs730882261, rs780175755, rs769054713, rs374909386, rs796052117, rs796052118, rs875989825, rs796052119, rs797045086, rs797045085, rs797044945, rs397515341, rs544674332, rs771663107, rs797045152, rs797045151, rs777031813, rs142800871, rs760123202, rs145742175, rs202094637, rs863224531, rs756235547, rs863224503, rs769458738, rs863224504, rs754867753, rs863224519, rs771214648, rs748688175, rs755553133, rs566755911, rs779506456, rs748618094, rs148891849, rs864622512, rs762664261, rs1060501460, rs753614861, rs72657316, rs200693106, rs876657683, rs876657637, rs752924362, rs750708201, rs878855279, rs773801386, rs878855280, rs571919972, rs755407407, rs775946081, rs755596256, rs878854458, rs878854457, rs762081081, rs144711161, rs878854441, rs72657321, rs757013900, rs878854444, rs878854445, rs878854446, rs72657393, rs878854435, rs878854436, rs1554294459, rs878855036, rs878854968, rs769284314, rs200669099, rs878855078, rs878855041, rs878855042, rs879253744, rs201213030, rs771920114, rs868755574, rs754776389, rs775700619, rs886037888, rs886037889, rs886039500, rs886039340, rs769346541, rs886041376, rs753101269, rs886042735, rs886044152, rs201943194, rs886044302, rs775696136, rs78484669, rs773498002, rs138890576, rs577069249, rs587621539, rs200901816, rs1060501456, rs773711154, rs752925056, rs1554020233, rs1060501464, rs769691189, rs767019228, rs1060501461, rs1060501467, rs1060501455, rs1060501459, rs1060501457, rs1060501466, rs1060501458, rs775051461, rs1060501454, rs781469274, rs759059925, rs766256391, rs1060503056, rs1060503063, rs1060503388, rs371374918, rs1060503107, rs144405450, rs752479330, rs1060503041, rs774903187, rs1060503104, rs763569711, rs1060503495, rs1060503515, rs752795172, rs1060501178, rs372572996, rs902156961, rs1060502829, rs1060503433, rs1060502202, rs200708870, rs775299709, rs370706991, rs141581673, rs774081599, rs757536895, rs756430359, rs770143722, rs1064792947, rs1060501861, rs1060500990, rs1060502831, rs372166228, rs1060501181, rs1060500123, rs772219642, rs1064795496, rs1064794014, rs575017579, rs1555354198, rs779490893, rs1555961832, rs1555961852, rs1555964133, rs768986129, rs1355068287, rs751845138, rs745800344, rs1553800956, rs1210953680, rs1007345781, rs1553805885, rs1553803540, rs1553804209, rs1553804640, rs746049858, rs1554049087, rs1554058577, rs1474945018, rs1554074565, rs753397685, rs754698253, rs1554033855, rs1353723750, rs763440781, rs367877988, rs747900131, rs749082955, rs1554062097, rs1554090622, rs1554090927, rs767716511, rs1554017211, rs753130398, rs745918507, rs1273352530, rs1354919632, rs368644722, rs1161303371, rs1283070426, rs755136231, rs1443540935, rs548521732, rs989235687, rs776686983, rs1554101045, rs116128702, rs1554132747, rs376576474, rs775136764, rs1034327724, rs902750903, rs750528020, rs753496815, rs771781357, rs1261703349, rs765025514, rs1554309352, rs1286036654, rs72657333, rs1554269295, rs373844629, rs767595964, rs1554293484, rs775720394, rs1212535211, rs1162526607, rs769637393, rs1554312483, rs1164659091, rs1275718084, rs202236144, rs972753865, rs147811057, rs1554248794, rs1554248887, rs950490534, rs1554291973, rs1275662909, rs1229952265, rs1554255966, rs1465404366, rs1409069267, rs1555174708, rs777108430, rs1555328022, rs1555328130, rs1555328047, rs758650222, rs1555526915, rs746242380, rs1555519999, rs762843285, rs758109864, rs1555614910, rs751191119, rs756868374, rs773796940, rs1555875358, rs556286752, rs1186608353, rs1555723797, rs745465871, rs773208371, rs745993158, rs1554082275, rs1555961677, rs1349668884, rs751610886, rs376496894, rs1554292398, rs1555327917, rs375053470, rs981267400, rs1555721837, rs769795916, rs1462578042, rs146412095, rs1553804220, rs1415346246, rs1553805740, rs1553804100, rs1275367324, rs886059965, rs1554081658, rs754982008, rs1554035330, rs1554050517, rs1554072027, rs756032160, rs77377082, rs79185772, rs775866092, rs1304504006, rs1193586811, rs1554082872, rs768881056, rs1554019966, rs1554247978, rs774393276, rs1554248617, rs766707325, rs756868889, rs1554249521, rs1437893220, rs770372463, rs749731714, rs1233811324, rs1554281038, rs757784023, rs551275210, rs750603177, rs769220870, rs1380083184, rs1554282583, rs763900107, rs769224534, rs747121305, rs1554822213, rs1555328087, rs1555327928, rs1233603821, rs745495583, rs1555527001, rs897911822, rs780116486, rs1421531868, rs746361802, rs1555968248, rs144037391, rs1305797678, rs1555071691, rs561237622, rs767760877, rs754773453, rs1555069023, rs372118787, rs774493427, rs1569237206, rs1560079213, rs1560086701, rs1560092440, rs1370489117, rs1561097225, rs914675446, rs748171209, rs1188507108, rs1561487416, rs1561073938, rs769691641, rs1561215953, rs1175877764, rs146087064, rs1561532139, rs574586008, rs1561117442, rs1444391928, rs145974361, rs1561836628, rs376903331, rs769929539, rs1436804091, rs1285431486, rs180897552, rs1562590250, rs1562684798, rs374107286, rs1562521048, rs1175443221, rs1563815206, rs753580394, rs1560090006, rs1560092160, rs778577109, rs1561122898, rs745885469, rs1561477725, rs757801770, rs1561524235, rs771956532, rs1391084505, rs769267893, rs1297857806, rs751920647, rs755782051, rs756616538, rs767713588, rs1297261096, rs768447289, rs374718437, rs1484826593, rs1561241156, rs769544175, rs565076112, rs1158185476, rs776176679, rs1562782355, rs1223799853, rs776791493, rs368248592, rs753649614, rs148810969, rs1346603171, rs371595543, rs1418585908, rs1567818236, rs761851970, rs748869874, rs766394527, rs753915759, rs1159887305, rs770403610, rs1240172375, rs764011276, rs770946088, rs764551914, rs1480671731, rs1568667609, rs1568709952, rs747233125, rs750658321, rs543369426, rs1569122408, rs1561449604, rs750649191, rs1564805053, rs1564805039, rs372959912, rs1564800859, rs577714887, rs766482965, rs1267599270, rs763238622, rs143007518, rs1567808990, rs969193071, rs867177356, rs1569162748, rs1561476089, rs377691013, rs1309805676, rs1569237077, rs1327282449, rs767308949, rs139416233, rs1567819753, rs1448501611, rs748600370, rs1601943268, rs750136163, rs1576941580, rs1256848235, rs747980515, rs1245822059, rs760742856, rs1579881985, rs762673561, rs1579942226, rs1579942510, rs1579980919, rs1580072662, rs369683202, rs1580150353, rs764948792, rs760595654, rs1580180757, rs1580203399, rs560398270, rs1309660408, rs981622980, rs1580363231, rs1580457416, rs767779749, rs116524991, rs1580543538, rs1580578744, rs1221785647, rs1252973555, rs1580809557, rs778780449, rs1164037667, rs1580853061, rs1580412021, rs1398588555, rs1561121987, rs753041231, rs748664881, rs1400425886, rs760122351, rs757935663, rs149070832, rs747123680, rs1582373132, rs1554149875, rs559143773, rs1583508118, rs949492765, rs1583567611, rs373946181, rs1237605731, rs756115857, rs1583806864, rs761855200, rs759332741, rs1489856215, rs201507046, rs1583517442, rs770251775, rs1586586381, rs369669370, rs1588663203, rs776979382, rs1003676784, rs1594608287, rs1489377964, rs1598330492, rs1598342751, rs755004291, rs1278589861, rs1277185772, rs763874734, rs753105954, rs373312648, rs369312501, rs1580179985, rs1580411207, rs1580465796, rs1579894454, rs1580143916, rs1582865345, rs200115379, rs372080325, rs1583570354, rs1583647043, rs72657354, rs767624733, rs1587089935, rs1587067513, rs1587091911, rs746849797, rs1598278059, rs1580731750, rs368110732, rs1597843267, rs1598348312, rs1217845018, rs1598372830, rs1598372841, rs1598372878, rs1598372791, rs1580402818, rs752527657, rs1601917999, rs1601922202, rs1601961064, rs1601982532, rs759302236, rs1597643228, rs1598293348, rs1601918140, rs745839898, rs1555961440, rs1601920423, rs907856232, rs281865302, rs1601972255, rs1601931052, rs1745570250, rs149368374, rs1601943325, rs1253689023, rs1575588483, rs1575215909, rs766982731, rs782603932, rs201244916, rs781864891, rs372955658, rs758482424, rs1601920532, rs1601924055, rs1601982474, rs1663812465, rs757823891, rs771057685, rs1711717951, rs1743041017, rs1744302993, rs1744309029, rs1744699899, rs1750171365, rs1750339039, rs1751962280, rs1752478598, rs1561215326, rs1264701182, rs1754234425, rs1465499923, rs1762460445, rs1762470883, rs148139814, rs760081822, rs1772369775, rs189080233, rs1778379197, rs1291689114, rs1176911729, rs769899297, rs1745583820, rs757303224, rs762267064, rs1416631904, rs749372718, rs72655998, rs756850884, rs765778415, rs1479385947, rs72658823, rs1162823375, rs370565524, rs746849639, rs973819096, rs1818211696, rs979934112, rs772133192, rs2051792816, rs2053367000, rs1567876609, rs2038617610, rs2085791151, rs770306950, rs2067876063, rs1468349011, rs1815572053, rs1268770869, rs1360420006, rs1772232595, rs774855011, rs1785786687, rs1788083949, rs2051550027, rs2037540861, rs753831132, rs937290981, rs766759197, rs1336208372, rs2067115815, rs866524368, rs1186795749, rs2067127718, rs1569235565, rs2067140471, rs2067144007, rs2067146007, rs2067157388, rs2067160273, rs2067161139, rs2067163605, rs2067164096, rs2067169934, rs2067172824, rs2067174697, rs1233849070, rs2067182354, rs2067182636, rs2067184023, rs2067187127, rs2067187618, rs2067188031, rs2067191335, rs2067193056, rs2067194648, rs2067406342, rs2067451355, rs2067700774, rs2067878321, rs2067878443, rs1718119792, rs1704217868, rs1704650728, rs1273109738, rs1768634470, rs1769225531, rs1298746949, rs1784195520, rs1788086604, rs1789346276, rs2058179740, rs2038565518, rs781949585, rs2038760864, rs1718195095, rs1783569129, rs1739374011, rs2082305577, rs2067148119, rs2067166789, rs2067172385, rs2067179633, rs2067200470, rs2067498092, rs771953930
Multiple myeloma	Multiple Myeloma	rs11540652, rs78311289, rs121913482, rs397507340, rs121913343, rs121913240, rs121913529, rs730882018, rs1057517992, rs121913527, rs756183569, rs746646631, rs1574706907, rs372078034, rs745380962, rs751524927, rs1575079076, rs1575446356, rs1478603808, rs1578264146, rs1578673280, rs1579484570, rs1579491104, rs1171390403, rs1582867955, rs764264135, rs951047896, rs890521687, rs1581495906, rs1587941402, rs1003155450, rs1588299621, rs1591100766, rs1591693095, rs1029296641, rs1593107841, rs1208575764, rs1593835248, rs1594406727, rs1594966387, rs1595889508, rs1159294530, rs1597073318, rs1135402871, rs1599413207, rs1418268495, rs1212577459, rs1600394490, rs1455074519, rs1603113792, rs1603415028, rs1602247047, rs1603452612	23955597, 22120009

Unknown
Disease term	Disease name	Evidence	References	Source
Neuroticism	Neuroticism			GWAS
Breast Cancer	Breast Cancer	Importantly, breast cancer patients bearing PRC2 LOF mutations displayed significantly worse prognosis compared with PRC2 wild-type patients		GWAS, CBGDA
Dementia	Dementia			GWAS
Mental Depression	Mental Depression			GWAS
Oligodendroglioma	Oligodendroglioma			GWAS

Associations from Text Mining
Disease Name	Relationship Type	References
Carcinoma Hepatocellular	Associate	39566392
Multiple Endocrine Neoplasia Type 1	Associate	30620390
Multiple Myeloma	Associate	27882933, 35013207
Neuroendocrine Tumors	Associate	30620390
Urinary Bladder Neoplasms	Associate	37968767