Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	55536
Gene name Gene Name - the full gene name approved by the HGNC.	Cell division cycle associated 7 like
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	CDCA7L
Synonyms (NCBI Gene) Gene synonyms aliases	JPO2, R1, RAM2
Chromosome Chromosome number	7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	7p15.3

Show/Hide all(117)

miRTarBase ID	miRNA	Experiments	Reference
MIRT019850	hsa-miR-375	Microarray	20215506
MIRT002722	hsa-miR-124-3p	Microarray	15685193
MIRT002722	hsa-miR-124-3p	Proteomics	18668037
MIRT041933	hsa-miR-484	CLASH	23622248
MIRT879064	hsa-miR-129-3p	CLIP-seq
MIRT879065	hsa-miR-3163	CLIP-seq
MIRT879066	hsa-miR-3613-3p	CLIP-seq
MIRT879067	hsa-miR-371b-5p	CLIP-seq
MIRT879068	hsa-miR-4687-5p	CLIP-seq
MIRT879069	hsa-miR-4698	CLIP-seq
MIRT879070	hsa-miR-499-3p	CLIP-seq
MIRT879071	hsa-miR-499a-3p	CLIP-seq
MIRT879072	hsa-miR-548k	CLIP-seq
MIRT879073	hsa-miR-548n	CLIP-seq
MIRT879074	hsa-miR-607	CLIP-seq
MIRT879075	hsa-miR-938	CLIP-seq
MIRT879076	hsa-miR-1238	CLIP-seq
MIRT879077	hsa-miR-1294	CLIP-seq
MIRT879078	hsa-miR-3198	CLIP-seq
MIRT879066	hsa-miR-3613-3p	CLIP-seq
MIRT879079	hsa-miR-3622a-5p	CLIP-seq
MIRT879080	hsa-miR-3652	CLIP-seq
MIRT879081	hsa-miR-371-5p	CLIP-seq
MIRT879067	hsa-miR-371b-5p	CLIP-seq
MIRT879082	hsa-miR-4309	CLIP-seq
MIRT879083	hsa-miR-431	CLIP-seq
MIRT879084	hsa-miR-4423-3p	CLIP-seq
MIRT879085	hsa-miR-4430	CLIP-seq
MIRT879086	hsa-miR-4505	CLIP-seq
MIRT879087	hsa-miR-4537	CLIP-seq
MIRT879088	hsa-miR-4652-3p	CLIP-seq
MIRT879089	hsa-miR-4710	CLIP-seq
MIRT879090	hsa-miR-4792	CLIP-seq
MIRT879070	hsa-miR-499-3p	CLIP-seq
MIRT879071	hsa-miR-499a-3p	CLIP-seq
MIRT879091	hsa-miR-548c-3p	CLIP-seq
MIRT879072	hsa-miR-548k	CLIP-seq
MIRT879073	hsa-miR-548n	CLIP-seq
MIRT879092	hsa-miR-586	CLIP-seq
MIRT879093	hsa-miR-767-5p	CLIP-seq
MIRT879094	hsa-miR-1285	CLIP-seq
MIRT879095	hsa-miR-1343	CLIP-seq
MIRT879096	hsa-miR-1470	CLIP-seq
MIRT879097	hsa-miR-3187-5p	CLIP-seq
MIRT879098	hsa-miR-4469	CLIP-seq
MIRT879099	hsa-miR-4667-3p	CLIP-seq
MIRT879100	hsa-miR-4793-3p	CLIP-seq
MIRT879101	hsa-miR-612	CLIP-seq
MIRT879093	hsa-miR-767-5p	CLIP-seq
MIRT1920351	hsa-miR-4501	CLIP-seq
MIRT879070	hsa-miR-499-3p	CLIP-seq
MIRT879071	hsa-miR-499a-3p	CLIP-seq
MIRT879072	hsa-miR-548k	CLIP-seq
MIRT879073	hsa-miR-548n	CLIP-seq
MIRT1920352	hsa-miR-548t	CLIP-seq
MIRT1920351	hsa-miR-4501	CLIP-seq
MIRT879070	hsa-miR-499-3p	CLIP-seq
MIRT879071	hsa-miR-499a-3p	CLIP-seq
MIRT879072	hsa-miR-548k	CLIP-seq
MIRT879073	hsa-miR-548n	CLIP-seq
MIRT1920352	hsa-miR-548t	CLIP-seq
MIRT1960590	hsa-miR-1185	CLIP-seq
MIRT1960591	hsa-miR-125a-3p	CLIP-seq
MIRT1960592	hsa-miR-139-5p	CLIP-seq
MIRT1960593	hsa-miR-15a	CLIP-seq
MIRT1960594	hsa-miR-15b	CLIP-seq
MIRT1960595	hsa-miR-16	CLIP-seq
MIRT1960596	hsa-miR-195	CLIP-seq
MIRT1960597	hsa-miR-214	CLIP-seq
MIRT1960598	hsa-miR-25	CLIP-seq
MIRT1960599	hsa-miR-302f	CLIP-seq
MIRT1960600	hsa-miR-32	CLIP-seq
MIRT1960601	hsa-miR-342-3p	CLIP-seq
MIRT1960602	hsa-miR-3605-5p	CLIP-seq
MIRT1960603	hsa-miR-3619-5p	CLIP-seq
MIRT1960604	hsa-miR-363	CLIP-seq
MIRT1960605	hsa-miR-367	CLIP-seq
MIRT1960606	hsa-miR-3679-5p	CLIP-seq
MIRT1960607	hsa-miR-424	CLIP-seq
MIRT1960608	hsa-miR-4325	CLIP-seq
MIRT1960609	hsa-miR-4690-5p	CLIP-seq
MIRT1960610	hsa-miR-4726-3p	CLIP-seq
MIRT1960611	hsa-miR-497	CLIP-seq
MIRT1960612	hsa-miR-548g	CLIP-seq
MIRT1960613	hsa-miR-582-5p	CLIP-seq
MIRT1960614	hsa-miR-761	CLIP-seq
MIRT1960615	hsa-miR-802	CLIP-seq
MIRT1960616	hsa-miR-92a	CLIP-seq
MIRT1960617	hsa-miR-92b	CLIP-seq
MIRT2500536	hsa-let-7a	CLIP-seq
MIRT2500537	hsa-let-7b	CLIP-seq
MIRT2500538	hsa-let-7c	CLIP-seq
MIRT2500539	hsa-let-7d	CLIP-seq
MIRT2500540	hsa-let-7e	CLIP-seq
MIRT2500541	hsa-let-7f	CLIP-seq
MIRT2500542	hsa-let-7g	CLIP-seq
MIRT2500543	hsa-let-7i	CLIP-seq
MIRT2500544	hsa-miR-122	CLIP-seq
MIRT2500545	hsa-miR-1251	CLIP-seq
MIRT2500546	hsa-miR-1256	CLIP-seq
MIRT2500547	hsa-miR-1287	CLIP-seq
MIRT2500548	hsa-miR-1305	CLIP-seq
MIRT2500549	hsa-miR-3135b	CLIP-seq
MIRT879066	hsa-miR-3613-3p	CLIP-seq
MIRT2500550	hsa-miR-362-5p	CLIP-seq
MIRT879081	hsa-miR-371-5p	CLIP-seq
MIRT879067	hsa-miR-371b-5p	CLIP-seq
MIRT2500551	hsa-miR-4432	CLIP-seq
MIRT2500552	hsa-miR-4458	CLIP-seq
MIRT2500553	hsa-miR-4500	CLIP-seq
MIRT2500554	hsa-miR-500b	CLIP-seq
MIRT2500555	hsa-miR-501-5p	CLIP-seq
MIRT2500556	hsa-miR-517b	CLIP-seq
MIRT879072	hsa-miR-548k	CLIP-seq
MIRT879073	hsa-miR-548n	CLIP-seq
MIRT2500557	hsa-miR-95	CLIP-seq
MIRT2500558	hsa-miR-98	CLIP-seq

Show/Hide all(11)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001650	Component	Fibrillar center	IDA
GO:0005515	Function	Protein binding	IPI	24705354, 25082813, 25416956, 25910212, 26871637, 27229929, 28169274, 29892012, 29997176, 32296183, 32814053
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	15994933
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005730	Component	Nucleolus	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0008284	Process	Positive regulation of cell population proliferation	IDA	15994933

MIM	HGNC	e!Ensembl
609685	30777	ENSG00000164649

Protein

UniProt ID

Q96GN5

Protein name

Cell division cycle-associated 7-like protein (Protein JPO2) (Transcription factor RAM2)

Protein function

Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in med

PDB

5YI9 , 6EMO

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF10497	zf-4CXXC_R1	345 → 443	Zinc-finger domain of monoamine-oxidase A repressor R1	Domain

Tissue specificity

TISSUE SPECIFICITY: Ubiquitous. Overexpressed in medulloblastoma. {ECO:0000269|PubMed:15654081, ECO:0000269|PubMed:15994933}.

Sequence

MELATRYQIPKEVADIFNAPSDDEEFVGFRDDVPMETLSSEESCDSFDSLESGKQQDVRF
HSKYFTEELRRIFIEDTDSETEDFAGFTQSDLNGKTNPEVMVVESDLSDDGKASLVSEEE
EDEEEDKATPRRSRSRRSSIGLRVAFQFPTKKLANKPDKNSSSEQLFSSARLQNEKKTIL
ERKKDCRQVIQREDSTSESEDDSRDESQESSDALLKRTMNIKENKAMLAQLLAELNSMPD
FFPVRTPTSASRKKTVRRAFSEGQITRRMNPTRSARPPEKFALENFTVSAAKFAEEFYSF
RRRKTIGGKCREYRRRHRISSFRPVEDITEEDLENVAITVRDKIYDKVLGNTCHQCRQKT
IDTKTVCRNQGCCGVRGQFCGPCLRNRYGEDVRSALLDPDWVCPPCRGICNCSYCRKRDG
RCATGILIHLAKFYGYDNVKEYLESLQKELVEDN

Sequence length

454

Interactions

View interactions

Show/Hide Unknown Diseases (5)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Breast Cancer	Breast cancer	N/A	N/A	GWAS
Dementia	Dementia	N/A	N/A	GWAS
Mental Depression	Major depressive disorder	N/A	N/A	GWAS
Neuroticism	Neuroticism	N/A	N/A	GWAS
Oligodendroglioma	Oligodendroglioma	N/A	N/A	GWAS

Show/Hide Text Mining Associations (5)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Carcinoma Hepatocellular	Associate	39566392
Multiple Endocrine Neoplasia Type 1	Associate	30620390
Multiple Myeloma	Associate	27882933, 35013207
Neuroendocrine Tumors	Associate	30620390
Urinary Bladder Neoplasms	Associate	37968767

CDCA7L (cell division cycle associated 7 like)