GPRC5D (G protein-coupled receptor class C group 5 member D)

Gene
Gene Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
55507
Gene name Gene Name - the full gene name approved by the HGNC.
G protein-coupled receptor class C group 5 member D
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
GPRC5D
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12p13.1
Summary Summary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene is a member of the G protein-coupled receptor family; however, the specific function of this gene has not yet been determined. [provided by RefSeq, Jul 2008]
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Protein Associated diseases
Show/Hide all(11)
GO ID Ontology Definition Evidence Reference
GO:0004930 Function G protein-coupled receptor activity IEA
GO:0005515 Function Protein binding IPI 32296183
GO:0005886 Component Plasma membrane IBA 21873635
GO:0005886 Component Plasma membrane NAS 11311935
GO:0007186 Process G protein-coupled receptor signaling pathway IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
607437 13310 ENSG00000111291
Protein
Gene Gene ontology Other IDs Protein Associated diseases
UniProt ID Q9NZD1
Protein name G-protein coupled receptor family C group 5 member D
Protein function G-protein coupled receptor involved in hard keratin expression and likely plays a role in the development of hair and nails.
PDB 8YZK , 9IMA
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00003 7tm_3 28 → 264 7 transmembrane sweet-taste receptor of 3 GCPR Family
Tissue specificity TISSUE SPECIFICITY: Widely expressed in the peripheral system. Expression pattern is high in pancreas, medium in kidney, small intestine, spleen and testis, low in lung, colon, leukocyte, prostate and thymus and not detectable in brain, heart, liver, plac
Sequence
Sequence length 345
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene Gene ontology Other IDs Protein Associated diseases
Show/Hide Unknown Diseases (2)
Unknown
Disease term Disease name Evidence References Source
Major affective disorder MAJOR AFFECTIVE DISORDER 2 15452587, 16389273 ClinVar
Diabetes Diabetes GWAS
Show/Hide Text Mining Associations (14)
Associations from Text Mining
Disease Name Relationship Type References
Carcinoma Hepatocellular Associate 12898236
Colonic Neoplasms Associate 16575208
Cytokine Release Syndrome Associate 40547010
Hypotrichosis Associate 18803659
Leukemia Myeloid Acute Associate 25213837
Leukemia Plasma Cell Associate 39676854
Leukocyte adhesion deficiency type 1 Inhibit 37653344
Multiple Myeloma Associate 23510526, 33089218, 33890981, 34471932, 37277826, 37653344, 38035078, 40547010, 40665393
Muscular Atrophy Associate 38100482
Neoplasms Associate 23510526, 27340777, 37277826, 40009503