MEG3 (maternally expressed 3)

Gene Gene information from NCBI Gene database.
Gene miRNA Transcription factors Gene ontology Other IDs Associated diseases
Entrez ID 55384
Gene name Maternally expressed 3
Gene symbol MEG3
Synonyms (NCBI Gene)
FP504GTL2LINC00023NCRNA00023PRO0518PRO2160onco-lncRNA-83prebp1
Chromosome 14
Chromosome location 14q32.2
Summary This gene is a maternally expressed imprinted gene. Multiple alternatively spliced transcript variants have been transcribed from this gene and all of them are long non-coding RNAs (lncRNAs). This gene is expressed in many normal tissues, but its expressi
miRNA miRNA information provided by mirtarbase database.
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Gene miRNA Transcription factors Gene ontology Other IDs Associated diseases
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miRTarBase ID miRNA Experiments Reference
MIRT731765 hsa-miR-181a-5p Luciferase reporter assayqRT-PCRWestern blot 26253106
MIRT731765 hsa-miR-181a-5p Luciferase reporter assayqRT-PCRWestern blot 26253106
MIRT731765 hsa-miR-181a-5p Luciferase reporter assayqRT-PCRWestern blot 26253106
MIRT731765 hsa-miR-181a-5p Luciferase reporter assayqRT-PCRWestern blot 26253106
MIRT731765 hsa-miR-181a-5p Luciferase reporter assayqRT-PCRWestern blot 26253106
Transcription factors Transcription factors information provided by TRRUST V2 database.
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Gene miRNA Transcription factors Gene ontology Other IDs Associated diseases
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Transcription factor Regulation Reference
CTCF Unknown 16331412
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Gene miRNA Transcription factors Gene ontology Other IDs Associated diseases
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GO ID Ontology Definition Evidence Reference
GO:0006325 Process Chromatin organization IEA
GO:0016442 Component RISC complex IEA
GO:0030308 Process Negative regulation of cell growth IEA
GO:0035195 Process MiRNA-mediated post-transcriptional gene silencing IEA
GO:0141180 Function DsDNA-RNA triple helix-forming chromatin adaptor activity IDA 38456652
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Transcription factors Gene ontology Other IDs Associated diseases
MIM HGNC e!Ensembl
605636 14575 ENSG00000214548
Interactions View interactions
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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Gene miRNA Transcription factors Gene ontology Other IDs Associated diseases
Show/Hide Unknown Diseases (1)
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
MEG3-related disorder Uncertain significance; Likely benign; Benign rs934263864, rs45570532, rs147252650, rs138219395, rs140305118, rs45497097, rs188511607, rs149936213, rs941575, rs4906023, rs3783357, rs7158663, rs58102709, rs4900478, rs1274309643
View all (21 more)		 RCV003403001
RCV003919118
RCV003907069
RCV003907097
RCV003924050
RCV003924150
RCV003929573
RCV003929854
RCV003974537
RCV003974117
RCV003982366
RCV003982409
RCV003917022
RCV003973935
RCV003909807
RCV003911870
RCV003942097
RCV003944156
RCV003944185
RCV003963886
RCV003963949
RCV003971986
RCV003931532
RCV003939554
RCV003939610
RCV003932316
RCV003951404
RCV003936769
RCV003942199
RCV003979020
RCV003962036
RCV003969554
RCV003971489
RCV003978969
RCV003962167
RCV003972118
Show/Hide Text Mining Associations (160)
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References
Abscess Associate 35422450
Acute Lung Injury Associate 31184231
Adenocarcinoma of Lung Associate 36101742
Adenoma Inhibit 21871428
Alzheimer Disease Associate 36895559
Asthma Associate 36726728
Autistic Disorder Associate 26106604
Bipolar Disorder Inhibit 35410190
Birk Barel Mental Retardation Dysmorphism Syndrome Associate 30801013
Brain Injuries Associate 30579356