MEG3 (maternally expressed 3)

Gene
Gene miRNA Transcription factors Gene ontology Other IDs Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
55384
Gene name Gene Name - the full gene name approved by the HGNC.
Maternally expressed 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
MEG3
Synonyms (NCBI Gene) Gene synonyms aliases
FP504, GTL2, LINC00023, NCRNA00023, PRO0518, PRO2160, onco-lncRNA-83, prebp1
Chromosome Chromosome number
14
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
14q32.2
Summary Summary of gene provided in NCBI Entrez Gene.
This gene is a maternally expressed imprinted gene. Multiple alternatively spliced transcript variants have been transcribed from this gene and all of them are long non-coding RNAs (lncRNAs). This gene is expressed in many normal tissues, but its expressi
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Transcription factors Gene ontology Other IDs Associated diseases
Show/Hide all(18)
miRTarBase ID miRNA Experiments Reference
MIRT731765 hsa-miR-181a-5p Luciferase reporter assay, qRT-PCR, Western blot 26253106
MIRT731765 hsa-miR-181a-5p Luciferase reporter assay, qRT-PCR, Western blot 26253106
MIRT731765 hsa-miR-181a-5p Luciferase reporter assay, qRT-PCR, Western blot 26253106
MIRT731765 hsa-miR-181a-5p Luciferase reporter assay, qRT-PCR, Western blot 26253106
MIRT731765 hsa-miR-181a-5p Luciferase reporter assay, qRT-PCR, Western blot 26253106
Transcription factors
Gene miRNA Transcription factors Gene ontology Other IDs Associated diseases
Show/Hide all(1)
Transcription factor Regulation Reference
CTCF Unknown 16331412
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Transcription factors Gene ontology Other IDs Associated diseases
Show/Hide all(2)
GO ID Ontology Definition Evidence Reference
GO:0030308 Process Negative regulation of cell growth IEA
GO:0035195 Process Gene silencing by miRNA IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Transcription factors Gene ontology Other IDs Associated diseases
MIM HGNC e!Ensembl
605636 14575 ENSG00000214548
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Transcription factors Gene ontology Other IDs Associated diseases
Show/Hide Causal Diseases (1)
Causal
Disease term Disease name dbSNP ID References
Diabetes mellitus Diabetes Mellitus, Insulin-Dependent rs587776515, rs61730328, rs606231121, rs606231122, rs79020217, rs77625743, rs78378398, rs606231123, rs1362648752, rs104893649, rs80356624, rs80356616, rs80356625, rs80356611, rs104894237
View all (293 more)		 19966805, 25751624
Show/Hide Unknown Diseases (2)
Unknown
Disease term Disease name Evidence References Source
Diabetes Diabetes GWAS
Breast Cancer Breast Cancer Importantly, breast cancer patients bearing PRC2 LOF mutations displayed significantly worse prognosis compared with PRC2 wild-type patients GWAS, CBGDA
Show/Hide Text Mining Associations (160)
Associations from Text Mining
Disease Name Relationship Type References
Abscess Associate 35422450
Acute Lung Injury Associate 31184231
Adenocarcinoma of Lung Associate 36101742
Adenoma Inhibit 21871428
Alzheimer Disease Associate 36895559
Asthma Associate 36726728
Autistic Disorder Associate 26106604
Bipolar Disorder Inhibit 35410190
Birk Barel Mental Retardation Dysmorphism Syndrome Associate 30801013
Brain Injuries Associate 30579356