Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	55351
Gene name Gene Name - the full gene name approved by the HGNC.	Serine/threonine kinase 32B
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	STK32B
Synonyms (NCBI Gene) Gene synonyms aliases	HSA250839, STK32, STKG6, YANK2
Chromosome Chromosome number	4
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	4p16.2
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a serine-threonine protein kinase. Serine-threonine kinases transfer phosphate molecules to the oxygen atoms of serine and threonine. A genomic deletion affecting this gene has been associated with Ellis-van Creveld syndrome, an autosoma

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miRTarBase ID	miRNA	Experiments
MIRT1397684	hsa-miR-1231	CLIP-seq
MIRT1397685	hsa-miR-3127-5p	CLIP-seq
MIRT1397686	hsa-miR-3164	CLIP-seq
MIRT1397687	hsa-miR-3619-3p	CLIP-seq
MIRT1397688	hsa-miR-3671	CLIP-seq
MIRT1397689	hsa-miR-3918	CLIP-seq
MIRT1397690	hsa-miR-4288	CLIP-seq
MIRT1397691	hsa-miR-4477a	CLIP-seq
MIRT1397692	hsa-miR-4649-3p	CLIP-seq
MIRT1397693	hsa-miR-4738-3p	CLIP-seq
MIRT1397694	hsa-miR-4769-3p	CLIP-seq
MIRT1397695	hsa-miR-583	CLIP-seq
MIRT1397696	hsa-miR-607	CLIP-seq
MIRT1397697	hsa-miR-632	CLIP-seq
MIRT2119067	hsa-miR-1238	CLIP-seq
MIRT2119068	hsa-miR-1271	CLIP-seq
MIRT2119069	hsa-miR-1273d	CLIP-seq
MIRT2119070	hsa-miR-145	CLIP-seq
MIRT2119071	hsa-miR-182	CLIP-seq
MIRT2119072	hsa-miR-3140-5p	CLIP-seq
MIRT2119073	hsa-miR-4267	CLIP-seq
MIRT2119074	hsa-miR-4691-5p	CLIP-seq
MIRT2119075	hsa-miR-548an	CLIP-seq
MIRT2119076	hsa-miR-660	CLIP-seq
MIRT2119077	hsa-miR-665	CLIP-seq
MIRT2119078	hsa-miR-96	CLIP-seq
MIRT1397684	hsa-miR-1231	CLIP-seq
MIRT2341381	hsa-miR-1267	CLIP-seq
MIRT2341382	hsa-miR-15a	CLIP-seq
MIRT2341383	hsa-miR-15b	CLIP-seq
MIRT2341384	hsa-miR-16	CLIP-seq
MIRT2341385	hsa-miR-1910	CLIP-seq
MIRT2341386	hsa-miR-195	CLIP-seq
MIRT1397686	hsa-miR-3164	CLIP-seq
MIRT2341387	hsa-miR-424	CLIP-seq
MIRT1397690	hsa-miR-4288	CLIP-seq
MIRT2341388	hsa-miR-4468	CLIP-seq
MIRT1397692	hsa-miR-4649-3p	CLIP-seq
MIRT2341389	hsa-miR-497	CLIP-seq
MIRT2341390	hsa-miR-595	CLIP-seq
MIRT1397697	hsa-miR-632	CLIP-seq
MIRT2119077	hsa-miR-665	CLIP-seq
MIRT2460681	hsa-miR-186	CLIP-seq
MIRT2460682	hsa-miR-3133	CLIP-seq
MIRT2460683	hsa-miR-3144-5p	CLIP-seq
MIRT2460684	hsa-miR-3191	CLIP-seq
MIRT2460685	hsa-miR-4652-5p	CLIP-seq
MIRT2460686	hsa-miR-548t	CLIP-seq
MIRT2460681	hsa-miR-186	CLIP-seq
MIRT2460682	hsa-miR-3133	CLIP-seq
MIRT2460683	hsa-miR-3144-5p	CLIP-seq
MIRT2460684	hsa-miR-3191	CLIP-seq
MIRT2635385	hsa-miR-4323	CLIP-seq
MIRT2635386	hsa-miR-4520a-3p	CLIP-seq
MIRT2460685	hsa-miR-4652-5p	CLIP-seq
MIRT2635387	hsa-miR-4802-3p	CLIP-seq
MIRT2460686	hsa-miR-548t	CLIP-seq
MIRT2460681	hsa-miR-186	CLIP-seq
MIRT2460682	hsa-miR-3133	CLIP-seq
MIRT2460683	hsa-miR-3144-5p	CLIP-seq
MIRT2460684	hsa-miR-3191	CLIP-seq
MIRT2635385	hsa-miR-4323	CLIP-seq
MIRT2635386	hsa-miR-4520a-3p	CLIP-seq
MIRT2460685	hsa-miR-4652-5p	CLIP-seq
MIRT2635387	hsa-miR-4802-3p	CLIP-seq
MIRT2460686	hsa-miR-548t	CLIP-seq

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GO ID	Ontology	Definition	Evidence
GO:0000166	Function	Nucleotide binding	IEA
GO:0004672	Function	Protein kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	IBA
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0005524	Function	ATP binding	IEA
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0035556	Process	Intracellular signal transduction	IBA
GO:0046872	Function	Metal ion binding	IEA
GO:0106310	Function	Protein serine kinase activity	IEA

MIM	HGNC	e!Ensembl
621309	14217	ENSG00000152953

Protein

UniProt ID

Q9NY57

Protein name

Serine/threonine-protein kinase 32B (EC 2.7.11.1) (Yet another novel kinase 2)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00069	Pkinase	23 → 283	Protein kinase domain	Domain

Sequence

MGGNHSHKPPVFDENEEVNFDHFQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCI
ERDEVRNVFRELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFTE
GTVKLYICELALALEYLQRYHIIHRDIKPDNILLDEHGHVHITDFNIATVVKGAERASSM
AGTKPYMAPEVFQVYMDRGPGYSYPVDWWSLGITAYELLRGWRPYEIHSVTPIDEILNMF
KVERVHYSSTWCKGMVALLRKLLTKDPESRVSSLHDIQSVPYLADMNWDAVFKKALMPGF
VPNKGRLNCDPTFELEEMILESKPLHKKKKRLAKNRSRDGTKDSCPLNGHLQHCLETVRE
EFIIFNREKLRRQQGQGSQLLDTDSRGGGQAQSKLQDGCNNNLLTHTCTRGCSS

Sequence length

414

Interactions

View interactions

Show/Hide Unknown Diseases (4)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Celiac disease	Celiac disease	N/A	N/A	GWAS
Long QT Syndrome	long qt syndrome	N/A	N/A	ClinVar
Schizophrenia	Schizophrenia	N/A	N/A	GWAS
Tremor	Essential tremor	N/A	N/A	GWAS

Show/Hide Text Mining Associations (11)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Calcinosis Cutis	Associate	24885002
Carcinoma Hepatocellular	Associate	35800238
Cleft Lip	Associate	20087401
Cleft Palate	Associate	20087401
Coronary Artery Disease	Associate	21626137
Essential Tremor	Associate	27797806, 28801652
Essential Tremor	Inhibit	28801652
general anxiety disorder	Associate	29604450
Inflammation	Associate	24885002
Neoplasm Metastasis	Associate	24885002
Neoplasms	Associate	24885002

STK32B (serine/threonine kinase 32B)