Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
55327
Gene name Gene Name - the full gene name approved by the HGNC.
Lin-7 cell polarity scaffold C
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
LIN7C
Synonyms (NCBI Gene) Gene synonyms aliases
LIN-7-C, LIN-7C, MALS-3, MALS3, VELI3
Chromosome Chromosome number
11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
11p14.1
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT002793 hsa-miR-1-3p Microarray 15685193
MIRT016113 hsa-miR-421 Sequencing 20371350
MIRT020569 hsa-miR-155-5p Proteomics 18668040
MIRT020569 hsa-miR-155-5p Reporter assay;Other 20584899
MIRT022176 hsa-miR-124-3p Proteomics;Microarray 18668037
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0002011 Process Morphogenesis of an epithelial sheet IMP 23201090
GO:0005515 Function Protein binding IPI 21849460, 24366813, 28514442, 32296183, 33961781
GO:0005737 Component Cytoplasm IDA 23201090
GO:0005886 Component Plasma membrane IDA 21849460, 23201090
GO:0005886 Component Plasma membrane IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
612332 17789 ENSG00000148943
Protein
UniProt ID Q9NUP9
Protein name Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3)
Protein function Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins t
PDB 3LRA
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02828 L27 14 67 L27 domain Domain
PF00595 PDZ 93 172 PDZ domain Domain
Sequence
Sequence length 197
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Dopamine Neurotransmitter Release Cycle
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Metabolic Syndrome Metabolic syndrome N/A N/A GWAS
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Huntington Disease Associate 33049985