TMA16 (translation machinery associated 16 homolog)

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID 55319
Gene name Translation machinery associated 16 homolog
Gene symbol TMA16
Synonyms (NCBI Gene)
C4orf43
Chromosome 4
Chromosome location 4q32.2
miRNA miRNA information provided by mirtarbase database.
61
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (61)
miRTarBase ID miRNA Experiments Reference
MIRT049795 hsa-miR-92a-3p CLASH 23622248
MIRT093394 hsa-miR-4293 PAR-CLIP 21572407
MIRT540298 hsa-miR-101-5p PAR-CLIP 21572407
MIRT093400 hsa-miR-892c-5p PAR-CLIP 21572407
MIRT093398 hsa-miR-1245b-3p PAR-CLIP 21572407
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
9
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (9)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 25416956, 31515488, 32296183, 32814053
GO:0005634 Component Nucleus HDA 21630459
GO:0005634 Component Nucleus IBA
GO:0005634 Component Nucleus IEA
GO:0005654 Component Nucleoplasm IDA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q96EY4
Protein name Translation machinery-associated protein 16
Protein function Involved in the biogenesis of the 60S ribosomal subunit in the nucleus.
PDB 6LSS , 6LU8 , 8FLA , 8FLB , 8FLC , 8IDT , 8IDY , 8INE , 8INF
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF11176 Tma16 13 → 163 Translation machinery-associated protein 16 Family
Sequence
Sequence length 203
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Show/Hide Unknown Diseases (1)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
SMALL CELL LUNG CARCINOMA — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations