RFK (riboflavin kinase)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
55312 |
Gene name
Gene Name - the full gene name approved by the HGNC.
|
Riboflavin kinase |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
RFK |
Synonyms (NCBI Gene)
Gene synonyms aliases
|
RIFK |
Chromosome
Chromosome number
|
9 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
9q21.13 |
Summary
Summary of gene provided in NCBI Entrez Gene.
|
Riboflavin kinase (RFK; EC 2.7.1.26) is an essential enzyme that catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN), an obligatory step in vitamin B2 utilization and flavin cofactor synthesis (Karthikeyan et al., |
miRNA
miRNA information provided by mirtarbase database.
|
|||||||||||||||||||||||||
|
Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|||||||
|
Protein | |||||||||||
UniProt ID | Q969G6 | ||||||||||
Protein name | Riboflavin kinase (EC 2.7.1.26) (ATP:riboflavin 5'-phosphotransferase) (Flavokinase) | ||||||||||
Protein function | Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD. Essential for TNF-induced reactive oxygen species (ROS) production. Through its interaction with bo | ||||||||||
PDB | 1NB0 , 1NB9 , 1P4M , 1Q9S | ||||||||||
Family and domains |
Pfam
|
||||||||||
Tissue specificity | TISSUE SPECIFICITY: Detected in brain, placenta and urinary bladder. | ||||||||||
Sequence |
|
||||||||||
Sequence length | 155 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
|
|||||||||
|
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
|
||||||||||||||||
|
||||||||||||||||
|