Gene Gene information from NCBI Gene database.
Entrez ID 55312
Gene name Riboflavin kinase
Gene symbol RFK
Synonyms (NCBI Gene)
RIFK
Chromosome 9
Chromosome location 9q21.13
Summary Riboflavin kinase (RFK; EC 2.7.1.26) is an essential enzyme that catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN), an obligatory step in vitamin B2 utilization and flavin cofactor synthesis (Karthikeyan et al.,
miRNA miRNA information provided by mirtarbase database.
398
miRTarBase ID miRNA Experiments Reference
MIRT021169 hsa-miR-186-5p Sequencing 20371350
MIRT027183 hsa-miR-103a-3p Sequencing 20371350
MIRT031929 hsa-miR-16-5p Sequencing 20371350
MIRT706732 hsa-miR-3976 HITS-CLIP 21572407
MIRT706731 hsa-miR-6514-5p HITS-CLIP 21572407
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
29
GO ID Ontology Definition Evidence Reference
GO:0000166 Function Nucleotide binding IEA
GO:0005515 Function Protein binding IPI 19641494, 32296183
GO:0005524 Function ATP binding IEA
GO:0005737 Component Cytoplasm IEA
GO:0005737 Component Cytoplasm NAS 12623014
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
613010 30324 ENSG00000135002
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q969G6
Protein name Riboflavin kinase (EC 2.7.1.26) (ATP:riboflavin 5'-phosphotransferase) (Flavokinase)
Protein function Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD. Essential for TNF-induced reactive oxygen species (ROS) production. Through its interaction with bo
PDB 1NB0 , 1NB9 , 1P4M , 1Q9S
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01687 Flavokinase 3 130 Riboflavin kinase Domain
Tissue specificity TISSUE SPECIFICITY: Detected in brain, placenta and urinary bladder.
Sequence
Sequence length 155
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  Riboflavin metabolism
Metabolic pathways
Biosynthesis of cofactors
  Vitamin B2 (riboflavin) metabolism