Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	55297
Gene name Gene Name - the full gene name approved by the HGNC.	Coiled-coil domain containing 91
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	CCDC91
Synonyms (NCBI Gene) Gene synonyms aliases	HSD8, p56
Chromosome Chromosome number	12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	12p11.22

Show/Hide all(140)

miRTarBase ID	miRNA	Experiments	Reference
MIRT625140	hsa-miR-8485	HITS-CLIP	23824327
MIRT625139	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT625138	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT629246	hsa-miR-5689	HITS-CLIP	23824327
MIRT625140	hsa-miR-8485	HITS-CLIP	23824327
MIRT625139	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT625138	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT629246	hsa-miR-5689	HITS-CLIP	23824327
MIRT625140	hsa-miR-8485	HITS-CLIP	23824327
MIRT625139	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT625138	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT629246	hsa-miR-5689	HITS-CLIP	23824327
MIRT625140	hsa-miR-8485	HITS-CLIP	23824327
MIRT625139	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT625138	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT629246	hsa-miR-5689	HITS-CLIP	23824327
MIRT625140	hsa-miR-8485	HITS-CLIP	23824327
MIRT625139	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT625138	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT625140	hsa-miR-8485	HITS-CLIP	23824327
MIRT625139	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT625138	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT629246	hsa-miR-5689	HITS-CLIP	23824327
MIRT625140	hsa-miR-8485	HITS-CLIP	23824327
MIRT625139	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT625138	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT629246	hsa-miR-5689	HITS-CLIP	23824327
MIRT625140	hsa-miR-8485	HITS-CLIP	23824327
MIRT625139	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT625138	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT629246	hsa-miR-5689	HITS-CLIP	23824327
MIRT625140	hsa-miR-8485	HITS-CLIP	23824327
MIRT625139	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT625138	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT629246	hsa-miR-5689	HITS-CLIP	23824327
MIRT625140	hsa-miR-8485	HITS-CLIP	23824327
MIRT625139	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT625138	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT870405	hsa-miR-1267	CLIP-seq
MIRT870406	hsa-miR-135a	CLIP-seq
MIRT870407	hsa-miR-135b	CLIP-seq
MIRT870408	hsa-miR-142-5p	CLIP-seq
MIRT870409	hsa-miR-188-3p	CLIP-seq
MIRT870410	hsa-miR-203	CLIP-seq
MIRT870411	hsa-miR-3074-3p	CLIP-seq
MIRT870412	hsa-miR-3119	CLIP-seq
MIRT870413	hsa-miR-3140-3p	CLIP-seq
MIRT870414	hsa-miR-335	CLIP-seq
MIRT870415	hsa-miR-340	CLIP-seq
MIRT870416	hsa-miR-361-5p	CLIP-seq
MIRT870417	hsa-miR-3664-5p	CLIP-seq
MIRT870418	hsa-miR-3689a-5p	CLIP-seq
MIRT870419	hsa-miR-3689b	CLIP-seq
MIRT870420	hsa-miR-3689e	CLIP-seq
MIRT870421	hsa-miR-3689f	CLIP-seq
MIRT870422	hsa-miR-369-3p	CLIP-seq
MIRT870423	hsa-miR-374a	CLIP-seq
MIRT870424	hsa-miR-374b	CLIP-seq
MIRT870425	hsa-miR-3973	CLIP-seq
MIRT870426	hsa-miR-410	CLIP-seq
MIRT870427	hsa-miR-4438	CLIP-seq
MIRT870428	hsa-miR-4452	CLIP-seq
MIRT870429	hsa-miR-450b-5p	CLIP-seq
MIRT870430	hsa-miR-4699-3p	CLIP-seq
MIRT870431	hsa-miR-4714-5p	CLIP-seq
MIRT870432	hsa-miR-4775	CLIP-seq
MIRT870433	hsa-miR-487a	CLIP-seq
MIRT870434	hsa-miR-494	CLIP-seq
MIRT870435	hsa-miR-507	CLIP-seq
MIRT870436	hsa-miR-518a-5p	CLIP-seq
MIRT870437	hsa-miR-520g	CLIP-seq
MIRT870438	hsa-miR-520h	CLIP-seq
MIRT870439	hsa-miR-527	CLIP-seq
MIRT870440	hsa-miR-532-3p	CLIP-seq
MIRT870441	hsa-miR-557	CLIP-seq
MIRT870442	hsa-miR-561	CLIP-seq
MIRT870443	hsa-miR-590-3p	CLIP-seq
MIRT870444	hsa-miR-653	CLIP-seq
MIRT1958396	hsa-miR-200b	CLIP-seq
MIRT1958397	hsa-miR-200c	CLIP-seq
MIRT1958398	hsa-miR-429	CLIP-seq
MIRT2195232	hsa-miR-1257	CLIP-seq
MIRT2195233	hsa-miR-181a	CLIP-seq
MIRT2195234	hsa-miR-181b	CLIP-seq
MIRT2195235	hsa-miR-181c	CLIP-seq
MIRT2195236	hsa-miR-181d	CLIP-seq
MIRT2195237	hsa-miR-4262	CLIP-seq
MIRT2195238	hsa-miR-4641	CLIP-seq
MIRT2195239	hsa-miR-4722-3p	CLIP-seq
MIRT2195240	hsa-miR-4793-5p	CLIP-seq
MIRT2195241	hsa-miR-520d-5p	CLIP-seq
MIRT2195242	hsa-miR-524-5p	CLIP-seq
MIRT2195232	hsa-miR-1257	CLIP-seq
MIRT870405	hsa-miR-1267	CLIP-seq
MIRT2498503	hsa-miR-127-5p	CLIP-seq
MIRT2498504	hsa-miR-132	CLIP-seq
MIRT870406	hsa-miR-135a	CLIP-seq
MIRT870407	hsa-miR-135b	CLIP-seq
MIRT870408	hsa-miR-142-5p	CLIP-seq
MIRT2195233	hsa-miR-181a	CLIP-seq
MIRT2195234	hsa-miR-181b	CLIP-seq
MIRT2195235	hsa-miR-181c	CLIP-seq
MIRT2195236	hsa-miR-181d	CLIP-seq
MIRT2498505	hsa-miR-186	CLIP-seq
MIRT870409	hsa-miR-188-3p	CLIP-seq
MIRT2498506	hsa-miR-2052	CLIP-seq
MIRT2498507	hsa-miR-212	CLIP-seq
MIRT870412	hsa-miR-3119	CLIP-seq
MIRT2498508	hsa-miR-3133	CLIP-seq
MIRT870413	hsa-miR-3140-3p	CLIP-seq
MIRT2498509	hsa-miR-3163	CLIP-seq
MIRT2498510	hsa-miR-33a	CLIP-seq
MIRT2498511	hsa-miR-33b	CLIP-seq
MIRT870415	hsa-miR-340	CLIP-seq
MIRT870417	hsa-miR-3664-5p	CLIP-seq
MIRT2498512	hsa-miR-3688-5p	CLIP-seq
MIRT2195237	hsa-miR-4262	CLIP-seq
MIRT2498513	hsa-miR-433	CLIP-seq
MIRT870427	hsa-miR-4438	CLIP-seq
MIRT870428	hsa-miR-4452	CLIP-seq
MIRT2498514	hsa-miR-4495	CLIP-seq
MIRT870429	hsa-miR-450b-5p	CLIP-seq
MIRT870431	hsa-miR-4714-5p	CLIP-seq
MIRT2195239	hsa-miR-4722-3p	CLIP-seq
MIRT870432	hsa-miR-4775	CLIP-seq
MIRT2195240	hsa-miR-4793-5p	CLIP-seq
MIRT870433	hsa-miR-487a	CLIP-seq
MIRT870435	hsa-miR-507	CLIP-seq
MIRT2498515	hsa-miR-548c-3p	CLIP-seq
MIRT870441	hsa-miR-557	CLIP-seq
MIRT870442	hsa-miR-561	CLIP-seq
MIRT870443	hsa-miR-590-3p	CLIP-seq
MIRT2498516	hsa-miR-664	CLIP-seq
MIRT2195232	hsa-miR-1257	CLIP-seq
MIRT2195233	hsa-miR-181a	CLIP-seq
MIRT2195234	hsa-miR-181b	CLIP-seq
MIRT2195235	hsa-miR-181c	CLIP-seq
MIRT2195236	hsa-miR-181d	CLIP-seq
MIRT2195237	hsa-miR-4262	CLIP-seq
MIRT2677515	hsa-miR-4766-5p	CLIP-seq

Show/Hide all(13)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005654	Component	Nucleoplasm	IDA
GO:0005794	Component	Golgi apparatus	IDA
GO:0005794	Component	Golgi apparatus	IEA
GO:0005802	Component	Trans-Golgi network	IBA
GO:0005802	Component	Trans-Golgi network	IDA	17596511
GO:0005829	Component	Cytosol	IEA
GO:0015031	Process	Protein transport	IEA
GO:0016020	Component	Membrane	IEA
GO:0042802	Function	Identical protein binding	IEA
GO:0048193	Process	Golgi vesicle transport	IEA
GO:0090160	Process	Golgi to lysosome transport	IBA
GO:0090160	Process	Golgi to lysosome transport	IMP	17596511

MIM	HGNC	e!Ensembl
617366	24855	ENSG00000123106

Protein

UniProt ID

Q7Z6B0

Protein name

Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein)

Protein function

Involved in the regulation of membrane traffic through the trans-Golgi network (TGN). Functions in close cooperation with the GGAs in the sorting of hydrolases to lysosomes.

PDB

1OM9

Family and domains

Tissue specificity

TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:12808037}.

Sequence

MDDDDFGGFEAAETFDGGSGETQTTSPAIPWAAFPAVSGVHLSPSSPEIVLDRDHSSSIG
CLSSDAIISSPENTHAANSIVSQTIPKAQIQQSTHTHLDISLFPLGLTDEKSNGTIALVD
DSEDPGANVSNIQLQQKISSLEIKLKVSEEEKQRIKQDVESLMEKHNVLEKGFLKEKEQE
AISFQDRYKELQEKHKQELEDMRKAGHEALSIIVDEYKALLQSSVKQQVEAIEKQYISAI
EKQAHKCEELLNAQHQRLLEMLDTEKELLKEKIKEALIQQSQEQKEILEKCLEEERQRNK
EALVSAAKLEKEAVKDAVLKVVEEERKNLEKAHAEERELWKTEHAKDQEKVSQEIQKAIQ
EQRKISQETVKAAIIEEQKRSEKAVEEAVKRTRDELIEYIKEQKRLDQVIRQRSLSSLEL
FLSCAQKQLSALIATEPVDIE

Sequence length

441

Interactions

View interactions

Show/Hide Unknown Diseases (10)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Attention Deficit Hyperactivity Disorder	Attention deficit hyperactivity disorder	N/A	N/A	GWAS
Autism Spectrum Disorder	autism spectrum disorder	N/A	N/A	GenCC
Breast Cancer	Postmenopausal breast cancer, Breast cancer (estrogen-receptor negative, progesterone-receptor negative, and human epidermal growth factor-receptor negative)	N/A	N/A	GWAS
Breast cancer	Breast cancer (estrogen-receptor negative), Breast cancer, Breast Cancer in BRCA1 mutation carriers	N/A	N/A	GWAS
Dementia	Dementia	N/A	N/A	GWAS
Hereditary Palmoplantar Keratoderma	punctate palmoplantar keratoderma	N/A	N/A	GenCC
Ischemic Stroke	Ischemic stroke	N/A	N/A	GWAS
Myopia	Myopia	N/A	N/A	GWAS
Polycystic Ovary Syndrome	Polycystic ovary syndrome	N/A	N/A	GWAS
Tremor	Essential tremor	N/A	N/A	GWAS

Show/Hide Text Mining Associations (5)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Breast Neoplasms	Associate	27459855
Hyperostosis Diffuse Idiopathic Skeletal	Associate	37156767
Lung Diseases	Associate	26635082
Neoplasm Recurrence Local	Associate	37393630
Ossification of the posterior longitudinal ligament of the spine	Associate	36990086

CCDC91 (coiled-coil domain containing 91)