KLHL26 (kelch like family member 26)

Gene

• Entrez ID: 55295
• Gene name: Kelch like family member 26
• Gene symbol: KLHL26
• Synonyms (NCBI Gene): -
• Chromosome: 19
• Chromosome location: 19p13.11

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT723879	hsa-miR-490-3p	HITS-CLIP	19536157
MIRT723878	hsa-miR-649	HITS-CLIP	19536157
MIRT723877	hsa-miR-3155a	HITS-CLIP	19536157
MIRT723876	hsa-miR-3155b	HITS-CLIP	19536157
MIRT723875	hsa-miR-484	HITS-CLIP	19536157
MIRT723874	hsa-miR-6728-3p	HITS-CLIP	19536157
MIRT723873	hsa-miR-3160-5p	HITS-CLIP	19536157
MIRT723872	hsa-miR-3191-5p	HITS-CLIP	19536157
MIRT723871	hsa-miR-4768-5p	HITS-CLIP	19536157
MIRT723870	hsa-miR-6833-3p	HITS-CLIP	19536157
MIRT723869	hsa-miR-6809-3p	HITS-CLIP	19536157
MIRT714530	hsa-miR-4686	HITS-CLIP	19536157
MIRT714529	hsa-miR-1251-3p	HITS-CLIP	19536157
MIRT675334	hsa-miR-450a-1-3p	HITS-CLIP	19536157
MIRT675333	hsa-miR-3122	HITS-CLIP	19536157
MIRT675332	hsa-miR-3913-5p	HITS-CLIP	19536157
MIRT675331	hsa-miR-887-5p	HITS-CLIP	19536157
MIRT675330	hsa-miR-6513-5p	HITS-CLIP	19536157
MIRT702358	hsa-miR-6771-3p	HITS-CLIP	23313552
MIRT702357	hsa-miR-4753-5p	HITS-CLIP	23313552
MIRT702356	hsa-miR-3922-5p	HITS-CLIP	23313552
MIRT702355	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT702354	hsa-miR-3190-5p	HITS-CLIP	23313552
MIRT702353	hsa-miR-3194-5p	HITS-CLIP	23313552
MIRT702352	hsa-miR-3926	HITS-CLIP	23313552
MIRT702351	hsa-miR-561-5p	HITS-CLIP	23313552
MIRT702350	hsa-miR-548s	HITS-CLIP	23313552
MIRT675367	hsa-miR-1910-3p	HITS-CLIP	23824327
MIRT675366	hsa-miR-6511a-5p	HITS-CLIP	23824327
MIRT675365	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT675364	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT675363	hsa-miR-940	HITS-CLIP	23824327
MIRT675362	hsa-miR-3622a-3p	HITS-CLIP	23824327
MIRT675361	hsa-miR-3622b-3p	HITS-CLIP	23824327
MIRT675360	hsa-miR-6765-3p	HITS-CLIP	23824327
MIRT675359	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT675358	hsa-miR-1827	HITS-CLIP	23824327
MIRT675357	hsa-miR-2467-3p	HITS-CLIP	23824327
MIRT675356	hsa-miR-3665	HITS-CLIP	23824327
MIRT675355	hsa-miR-3612	HITS-CLIP	23824327
MIRT675354	hsa-miR-650	HITS-CLIP	23824327
MIRT675353	hsa-miR-4736	HITS-CLIP	23824327
MIRT675352	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT675351	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT675350	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT675349	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT675348	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT675347	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT675346	hsa-miR-3165	HITS-CLIP	23824327
MIRT675345	hsa-miR-7977	HITS-CLIP	23824327
MIRT675344	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT675343	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT675342	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT675341	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT675340	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT675339	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT675338	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT675337	hsa-miR-3689c	HITS-CLIP	23824327
MIRT675336	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT675335	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT675334	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT675333	hsa-miR-3122	HITS-CLIP	23824327
MIRT675332	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT675331	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT675330	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT723879	hsa-miR-490-3p	HITS-CLIP	19536157
MIRT723878	hsa-miR-649	HITS-CLIP	19536157
MIRT723877	hsa-miR-3155a	HITS-CLIP	19536157
MIRT723876	hsa-miR-3155b	HITS-CLIP	19536157
MIRT723875	hsa-miR-484	HITS-CLIP	19536157
MIRT723874	hsa-miR-6728-3p	HITS-CLIP	19536157
MIRT723873	hsa-miR-3160-5p	HITS-CLIP	19536157
MIRT723872	hsa-miR-3191-5p	HITS-CLIP	19536157
MIRT723871	hsa-miR-4768-5p	HITS-CLIP	19536157
MIRT723870	hsa-miR-6833-3p	HITS-CLIP	19536157
MIRT723869	hsa-miR-6809-3p	HITS-CLIP	19536157
MIRT714530	hsa-miR-4686	HITS-CLIP	19536157
MIRT714529	hsa-miR-1251-3p	HITS-CLIP	19536157
MIRT675334	hsa-miR-450a-1-3p	HITS-CLIP	19536157
MIRT675333	hsa-miR-3122	HITS-CLIP	19536157
MIRT675332	hsa-miR-3913-5p	HITS-CLIP	19536157
MIRT675331	hsa-miR-887-5p	HITS-CLIP	19536157
MIRT675330	hsa-miR-6513-5p	HITS-CLIP	19536157
MIRT702358	hsa-miR-6771-3p	HITS-CLIP	23313552
MIRT702357	hsa-miR-4753-5p	HITS-CLIP	23313552
MIRT702356	hsa-miR-3922-5p	HITS-CLIP	23313552
MIRT702355	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT702354	hsa-miR-3190-5p	HITS-CLIP	23313552
MIRT702353	hsa-miR-3194-5p	HITS-CLIP	23313552
MIRT702352	hsa-miR-3926	HITS-CLIP	23313552
MIRT702351	hsa-miR-561-5p	HITS-CLIP	23313552
MIRT702350	hsa-miR-548s	HITS-CLIP	23313552
MIRT675367	hsa-miR-1910-3p	HITS-CLIP	23824327
MIRT675366	hsa-miR-6511a-5p	HITS-CLIP	23824327
MIRT675365	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT675364	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT675363	hsa-miR-940	HITS-CLIP	23824327
MIRT675362	hsa-miR-3622a-3p	HITS-CLIP	23824327
MIRT675361	hsa-miR-3622b-3p	HITS-CLIP	23824327
MIRT675360	hsa-miR-6765-3p	HITS-CLIP	23824327
MIRT675359	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT675358	hsa-miR-1827	HITS-CLIP	23824327
MIRT675357	hsa-miR-2467-3p	HITS-CLIP	23824327
MIRT675356	hsa-miR-3665	HITS-CLIP	23824327
MIRT675355	hsa-miR-3612	HITS-CLIP	23824327
MIRT675354	hsa-miR-650	HITS-CLIP	23824327
MIRT675353	hsa-miR-4736	HITS-CLIP	23824327
MIRT675352	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT675351	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT675350	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT675349	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT675348	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT675347	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT675346	hsa-miR-3165	HITS-CLIP	23824327
MIRT675345	hsa-miR-7977	HITS-CLIP	23824327
MIRT675344	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT675343	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT675342	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT675341	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT675340	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT675339	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT675338	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT675337	hsa-miR-3689c	HITS-CLIP	23824327
MIRT675336	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT675335	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT675334	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT675333	hsa-miR-3122	HITS-CLIP	23824327
MIRT675332	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT675331	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT675330	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT1098136	hsa-miR-148a	CLIP-seq
MIRT1098137	hsa-miR-148b	CLIP-seq
MIRT1098138	hsa-miR-152	CLIP-seq
MIRT1098139	hsa-miR-15a	CLIP-seq
MIRT1098140	hsa-miR-15b	CLIP-seq
MIRT1098141	hsa-miR-16	CLIP-seq
MIRT1098142	hsa-miR-1915	CLIP-seq
MIRT1098143	hsa-miR-195	CLIP-seq
MIRT1098144	hsa-miR-3157-5p	CLIP-seq
MIRT1098145	hsa-miR-3166	CLIP-seq
MIRT1098146	hsa-miR-3189-5p	CLIP-seq
MIRT1098147	hsa-miR-3202	CLIP-seq
MIRT1098148	hsa-miR-3617	CLIP-seq
MIRT1098149	hsa-miR-382	CLIP-seq
MIRT1098150	hsa-miR-3913-3p	CLIP-seq
MIRT1098151	hsa-miR-424	CLIP-seq
MIRT1098152	hsa-miR-4481	CLIP-seq
MIRT1098153	hsa-miR-4524	CLIP-seq
MIRT1098154	hsa-miR-4533	CLIP-seq
MIRT1098155	hsa-miR-4666-5p	CLIP-seq
MIRT1098156	hsa-miR-4676-5p	CLIP-seq
MIRT1098157	hsa-miR-4691-3p	CLIP-seq
MIRT1098158	hsa-miR-4694-3p	CLIP-seq
MIRT1098159	hsa-miR-4710	CLIP-seq
MIRT1098160	hsa-miR-4745-5p	CLIP-seq
MIRT1098161	hsa-miR-4758-3p	CLIP-seq
MIRT1098162	hsa-miR-4758-5p	CLIP-seq
MIRT1098163	hsa-miR-4792	CLIP-seq
MIRT1098164	hsa-miR-4802-3p	CLIP-seq
MIRT1098165	hsa-miR-497	CLIP-seq
MIRT1098166	hsa-miR-503	CLIP-seq
MIRT1098167	hsa-miR-575	CLIP-seq
MIRT1098168	hsa-miR-641	CLIP-seq
MIRT1098169	hsa-miR-646	CLIP-seq
MIRT1098139	hsa-miR-15a	CLIP-seq
MIRT1098140	hsa-miR-15b	CLIP-seq
MIRT1098141	hsa-miR-16	CLIP-seq
MIRT1098143	hsa-miR-195	CLIP-seq
MIRT2026689	hsa-miR-3153	CLIP-seq
MIRT2026690	hsa-miR-3179	CLIP-seq
MIRT1098148	hsa-miR-3617	CLIP-seq
MIRT1098149	hsa-miR-382	CLIP-seq
MIRT1098150	hsa-miR-3913-3p	CLIP-seq
MIRT1098151	hsa-miR-424	CLIP-seq
MIRT1098152	hsa-miR-4481	CLIP-seq
MIRT1098153	hsa-miR-4524	CLIP-seq
MIRT2026691	hsa-miR-4635	CLIP-seq
MIRT1098160	hsa-miR-4745-5p	CLIP-seq
MIRT2026692	hsa-miR-4780	CLIP-seq
MIRT1098165	hsa-miR-497	CLIP-seq
MIRT1098166	hsa-miR-503	CLIP-seq
MIRT1098168	hsa-miR-641	CLIP-seq
MIRT1098169	hsa-miR-646	CLIP-seq
MIRT2257939	hsa-miR-1321	CLIP-seq
MIRT1098139	hsa-miR-15a	CLIP-seq
MIRT1098140	hsa-miR-15b	CLIP-seq
MIRT1098141	hsa-miR-16	CLIP-seq
MIRT1098143	hsa-miR-195	CLIP-seq
MIRT1098146	hsa-miR-3189-5p	CLIP-seq
MIRT2257940	hsa-miR-3192	CLIP-seq
MIRT1098148	hsa-miR-3617	CLIP-seq
MIRT1098149	hsa-miR-382	CLIP-seq
MIRT1098150	hsa-miR-3913-3p	CLIP-seq
MIRT1098151	hsa-miR-424	CLIP-seq
MIRT1098152	hsa-miR-4481	CLIP-seq
MIRT1098153	hsa-miR-4524	CLIP-seq
MIRT1098155	hsa-miR-4666-5p	CLIP-seq
MIRT1098159	hsa-miR-4710	CLIP-seq
MIRT2257941	hsa-miR-4739	CLIP-seq
MIRT1098160	hsa-miR-4745-5p	CLIP-seq
MIRT2257942	hsa-miR-4756-5p	CLIP-seq
MIRT1098161	hsa-miR-4758-3p	CLIP-seq
MIRT1098162	hsa-miR-4758-5p	CLIP-seq
MIRT1098163	hsa-miR-4792	CLIP-seq
MIRT1098164	hsa-miR-4802-3p	CLIP-seq
MIRT1098165	hsa-miR-497	CLIP-seq
MIRT1098166	hsa-miR-503	CLIP-seq
MIRT2257943	hsa-miR-605	CLIP-seq
MIRT1098168	hsa-miR-641	CLIP-seq
MIRT1098169	hsa-miR-646	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25036637, 32296183, 32814053, 33961781

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q53HC5
• Protein name: Kelch-like protein 26
• Protein function: May play a role in endo(sarco)plasmic reticulum (ER/SR) mitochondrial signaling (PubMed:37204873). May be part of the ubiquitin-proteasome system (UPS) and affect ubiquitination and degradation of target substrates in cardiomyocytes (PubMed:3720
• PDB: 9ETW
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00651	BTB	53 → 159	BTB/POZ domain	Domain
  PF07707	BACK	165 → 266	BTB And C-terminal Kelch	Domain
  PF01344	Kelch_1	402 → 442	Kelch motif	Repeat
  PF01344	Kelch_1	452 → 495	Kelch motif	Repeat
  PF01344	Kelch_1	497 → 546	Kelch motif	Repeat
  PF01344	Kelch_1	550 → 590	Kelch motif	Repeat

• Sequence:

  MAESGGSSGGAGGGGAFGAGPGPERPNSTADKNGALKCTFSAPSHSTSLLQGLATLRAQG
  QLLDVVLTINREAFPAHKVVLAACSDYFRAMFTGGMREASQDVIELKGVSARGLRHIIDF
  AYSAEVTLDLDCVQDVLGAAVFLQMLPVVELCEEFLKAAMSVETCLNIGQMATTFSLASL
  RESVDAFTFRHFLQIAEEEDFLRLPLERLVFFLQSNRLQSCAEIDLFRAAVRWLQHDPAR
  RPRASHVLCHIRFPLMQSSELVDSVQTLDIMVEDVLCRQYLLEAFNYQVLPFRQHEMQSP
  RTAVRSDVPSLVTFGGTPYTDSDRSVSSKVYQLPEPGARHFRELTEMEVGCSHTCVAVLD
  NFVYVAGGQHLQYRSGEGAVDACYRYDPHLNRWLRLQAMQESRIQFQLNVLCGMVYATGG
  RNRAGSLASVERYCPRRNEWGYACSLKRRTWGHAGAASGGRLYISGGYGISVEDKKALHC
  YDPVADQWEFKAPMSEPRVLHAMVGAGGRIYALGGRMDHVDRCFDVLAVEYYVPETDQWT
  SVSPMRAGQSEAGCCLLERKIYIVGGYNWRLNNVTGIVQVYNTDTDEWERDLHFPESFAG
  IACAPVLLPRAGTRR

• Sequence length: 615