Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	55289
Gene name	Acyl-CoA oxidase like
Gene symbol	ACOXL
Synonyms (NCBI Gene)	ACOX4
Chromosome	2
Chromosome location	2q13

Show/Hide all (4)

miRTarBase ID	miRNA	Experiments
MIRT2166182	hsa-miR-4706	CLIP-seq
MIRT2166183	hsa-miR-4749-5p	CLIP-seq
MIRT2166184	hsa-miR-4781-5p	CLIP-seq
MIRT2166185	hsa-miR-939	CLIP-seq

Show/Hide all (16)

GO ID	Ontology	Definition	Evidence
GO:0003674	Function	Molecular_function	ND
GO:0003997	Function	Acyl-CoA oxidase activity	IBA
GO:0003997	Function	Acyl-CoA oxidase activity	IEA
GO:0005504	Function	Fatty acid binding	IBA
GO:0005575	Component	Cellular_component	ND
GO:0005777	Component	Peroxisome	IBA
GO:0005777	Component	Peroxisome	IEA
GO:0005782	Component	Peroxisomal matrix	TAS
GO:0006631	Process	Fatty acid metabolic process	IEA
GO:0006635	Process	Fatty acid beta-oxidation	IEA
GO:0008150	Process	Biological_process	ND
GO:0016491	Function	Oxidoreductase activity	IEA
GO:0016627	Function	Oxidoreductase activity, acting on the CH-CH group of donors	IEA
GO:0033540	Process	Fatty acid beta-oxidation using acyl-CoA oxidase	IBA
GO:0050660	Function	Flavin adenine dinucleotide binding	IBA
GO:0071949	Function	FAD binding	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q9NUZ1

Protein name

Acyl-coenzyme A oxidase-like protein (Acyl-CoA oxidase-like protein) (EC 1.3.3.-)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF02770	Acyl-CoA_dh_M	89 → 197	Acyl-CoA dehydrogenase, middle domain	Domain
PF00441	Acyl-CoA_dh_1	228 → 390	Acyl-CoA dehydrogenase, C-terminal domain	Domain
PF01756	ACOX	431 → 546	Acyl-CoA oxidase	Family

Sequence

MRALTVQRVKFAMDLPLLKRAGQDLAEKTKNFVSRSLVIGEVLSMADMATGVKCGIIYWL
FGGAIRNLGSPEHVTKWFQPLQEQKYTGMFAMTERGHGSNARGIQTEATFDLSAQEFVID
TPCENAEKMYIGNAMYGNYAAVFAQLIIDGRSQGPHCFIVPVRDENGSLYPGVTAIDMMY
KEGLHGVDNGILIFDKVRIPRENLLDKFGSVAPDGQYHSPIRNKSARFNAMLAALTPSRL
AVAFQAMGAMKLGLTIAIRYSHSRRQFGPKTKEEVKIIEHQTQTLRLMPHLATALALTFV
SRYAGALLDEDVFQGKELVNSRSLQALVAGLKAYSTWENIRCLQDCRECTGGMGYMMENR
ISGLKCDTDVFATFEGDDVVMLQVVGRELLAQYTKQYEEKPLFGLLQNWAESVGDKLRTS
FLAFNMDTVDDLAFLLKAVKFRERVLQRGLVARIYYKVKTKKEDFFHAWNSCLHHVASLS
LAHTHRVTLEQFSLAVKSCPDQEDQTLLMKFCLLYGTKLVFQERAWYLEHKYLTPMASTR
IRNQERC

Sequence length

547

Interactions

View interactions

	Reactome
			Beta-oxidation of pristanoyl-CoA

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Malignant lymphoma, large B-cell, diffuse	Uncertain significance	rs561949547	RCV005939093

Show/Hide Text Mining Associations (8)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Arthritis Rheumatoid	Associate	39930543
Atherosclerosis	Associate	37173646
Brain Ischemia	Associate	37173646
Diabetes Mellitus Type 2	Associate	23552671
Leukemia B Cell	Associate	20855867
Leukemia Lymphocytic Chronic B Cell	Associate	20731705, 20855867
Leukemia Prolymphocytic T Cell	Associate	20553269
Multiple Myeloma	Associate	33751038

ACOXL (acyl-CoA oxidase like)