Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
55286
Gene name Gene Name - the full gene name approved by the HGNC.
PDCD10 and GCKIII kinases associated 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
PGCKA1
Synonyms (NCBI Gene) Gene synonyms aliases
C4orf19
Chromosome Chromosome number
4
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
4p14
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT610180 hsa-miR-3976 HITS-CLIP 23824327
MIRT610179 hsa-miR-1273f HITS-CLIP 23824327
MIRT610178 hsa-miR-376a-3p HITS-CLIP 23824327
MIRT610177 hsa-miR-376b-3p HITS-CLIP 23824327
MIRT610176 hsa-miR-335-3p HITS-CLIP 23824327
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 25416956, 28514442, 31515488, 32296183
GO:0005654 Component Nucleoplasm IDA
GO:0030054 Component Cell junction IDA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein
UniProt ID Q8IY42
Protein name PDCD10 and GCKIII kinases-associated protein 1
Protein function Acts as a tumor suppressor (PubMed:36882524, PubMed:38517886). Acts as a tumor suppressor for colorectal cancer cell proliferation by targeting KEAP1/USP17/ELK1/CDK6 axis (PubMed:36882524). {ECO:0000269|PubMed:36882524, ECO:0000269|PubMed:385178
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15770 DUF4699 9 314 Domain of unknown function (DUF4699) Family
Sequence
Sequence length 314
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Cholestasis Cholestasis rs121909103, rs751511532, rs376368459, rs762702807, rs1578490102, rs1578499691, rs1578504946, rs1317656688, rs199791850, rs1452792080, rs1578491039 27989131
Leukemia Leukemia, Myelocytic, Acute rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297 27903959