PGCKA1 (PDCD10 and GCKIII kinases associated 1)

Gene

• Entrez ID: 55286
• Gene name: PDCD10 and GCKIII kinases associated 1
• Gene symbol: PGCKA1
• Synonyms (NCBI Gene): C4orf19
• Chromosome: 4
• Chromosome location: 4p14

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT610180	hsa-miR-3976	HITS-CLIP	23824327
MIRT610179	hsa-miR-1273f	HITS-CLIP	23824327
MIRT610178	hsa-miR-376a-3p	HITS-CLIP	23824327
MIRT610177	hsa-miR-376b-3p	HITS-CLIP	23824327
MIRT610176	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT610180	hsa-miR-3976	HITS-CLIP	23824327
MIRT610179	hsa-miR-1273f	HITS-CLIP	23824327
MIRT610178	hsa-miR-376a-3p	HITS-CLIP	23824327
MIRT610177	hsa-miR-376b-3p	HITS-CLIP	23824327
MIRT610176	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT610180	hsa-miR-3976	HITS-CLIP	23824327
MIRT610179	hsa-miR-1273f	HITS-CLIP	23824327
MIRT610178	hsa-miR-376a-3p	HITS-CLIP	23824327
MIRT610177	hsa-miR-376b-3p	HITS-CLIP	23824327
MIRT610176	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT610180	hsa-miR-3976	HITS-CLIP	23824327
MIRT610179	hsa-miR-1273f	HITS-CLIP	23824327
MIRT610178	hsa-miR-376a-3p	HITS-CLIP	23824327
MIRT610177	hsa-miR-376b-3p	HITS-CLIP	23824327
MIRT610176	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT610180	hsa-miR-3976	HITS-CLIP	23824327
MIRT610179	hsa-miR-1273f	HITS-CLIP	23824327
MIRT610178	hsa-miR-376a-3p	HITS-CLIP	23824327
MIRT610177	hsa-miR-376b-3p	HITS-CLIP	23824327
MIRT610176	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT610180	hsa-miR-3976	HITS-CLIP	23824327
MIRT610179	hsa-miR-1273f	HITS-CLIP	23824327
MIRT610178	hsa-miR-376a-3p	HITS-CLIP	23824327
MIRT610177	hsa-miR-376b-3p	HITS-CLIP	23824327
MIRT610176	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT610180	hsa-miR-3976	HITS-CLIP	23824327
MIRT610179	hsa-miR-1273f	HITS-CLIP	23824327
MIRT610178	hsa-miR-376a-3p	HITS-CLIP	23824327
MIRT610177	hsa-miR-376b-3p	HITS-CLIP	23824327
MIRT610176	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT610180	hsa-miR-3976	HITS-CLIP	23824327
MIRT610179	hsa-miR-1273f	HITS-CLIP	23824327
MIRT610178	hsa-miR-376a-3p	HITS-CLIP	23824327
MIRT610177	hsa-miR-376b-3p	HITS-CLIP	23824327
MIRT610176	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT610180	hsa-miR-3976	HITS-CLIP	23824327
MIRT610179	hsa-miR-1273f	HITS-CLIP	23824327
MIRT610178	hsa-miR-376a-3p	HITS-CLIP	23824327
MIRT610177	hsa-miR-376b-3p	HITS-CLIP	23824327
MIRT610176	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT610180	hsa-miR-3976	HITS-CLIP	23824327
MIRT610179	hsa-miR-1273f	HITS-CLIP	23824327
MIRT610178	hsa-miR-376a-3p	HITS-CLIP	23824327
MIRT610177	hsa-miR-376b-3p	HITS-CLIP	23824327
MIRT610176	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT610180	hsa-miR-3976	HITS-CLIP	23824327
MIRT610179	hsa-miR-1273f	HITS-CLIP	23824327
MIRT610178	hsa-miR-376a-3p	HITS-CLIP	23824327
MIRT610177	hsa-miR-376b-3p	HITS-CLIP	23824327
MIRT610176	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT610180	hsa-miR-3976	HITS-CLIP	23824327
MIRT610179	hsa-miR-1273f	HITS-CLIP	23824327
MIRT610178	hsa-miR-376a-3p	HITS-CLIP	23824327
MIRT610177	hsa-miR-376b-3p	HITS-CLIP	23824327
MIRT610176	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT610180	hsa-miR-3976	HITS-CLIP	23824327
MIRT610179	hsa-miR-1273f	HITS-CLIP	23824327
MIRT610178	hsa-miR-376a-3p	HITS-CLIP	23824327
MIRT610177	hsa-miR-376b-3p	HITS-CLIP	23824327
MIRT610176	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT610180	hsa-miR-3976	HITS-CLIP	23824327
MIRT610179	hsa-miR-1273f	HITS-CLIP	23824327
MIRT610178	hsa-miR-376a-3p	HITS-CLIP	23824327
MIRT610177	hsa-miR-376b-3p	HITS-CLIP	23824327
MIRT610176	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT610180	hsa-miR-3976	HITS-CLIP	23824327
MIRT610179	hsa-miR-1273f	HITS-CLIP	23824327
MIRT610178	hsa-miR-376a-3p	HITS-CLIP	23824327
MIRT610177	hsa-miR-376b-3p	HITS-CLIP	23824327
MIRT610176	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT610180	hsa-miR-3976	HITS-CLIP	23824327
MIRT610179	hsa-miR-1273f	HITS-CLIP	23824327
MIRT610178	hsa-miR-376a-3p	HITS-CLIP	23824327
MIRT610177	hsa-miR-376b-3p	HITS-CLIP	23824327
MIRT610176	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT610180	hsa-miR-3976	HITS-CLIP	23824327
MIRT610179	hsa-miR-1273f	HITS-CLIP	23824327
MIRT610178	hsa-miR-376a-3p	HITS-CLIP	23824327
MIRT610177	hsa-miR-376b-3p	HITS-CLIP	23824327
MIRT610176	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT610180	hsa-miR-3976	HITS-CLIP	23824327
MIRT610179	hsa-miR-1273f	HITS-CLIP	23824327
MIRT610178	hsa-miR-376a-3p	HITS-CLIP	23824327
MIRT610177	hsa-miR-376b-3p	HITS-CLIP	23824327
MIRT610176	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT610180	hsa-miR-3976	HITS-CLIP	23824327
MIRT610179	hsa-miR-1273f	HITS-CLIP	23824327
MIRT610178	hsa-miR-376a-3p	HITS-CLIP	23824327
MIRT610177	hsa-miR-376b-3p	HITS-CLIP	23824327
MIRT610176	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT610180	hsa-miR-3976	HITS-CLIP	23824327
MIRT610179	hsa-miR-1273f	HITS-CLIP	23824327
MIRT610178	hsa-miR-376a-3p	HITS-CLIP	23824327
MIRT610177	hsa-miR-376b-3p	HITS-CLIP	23824327
MIRT610176	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT847942	hsa-miR-105	CLIP-seq
MIRT847943	hsa-miR-1289	CLIP-seq
MIRT847944	hsa-miR-129-5p	CLIP-seq
MIRT847945	hsa-miR-143	CLIP-seq
MIRT847946	hsa-miR-208a	CLIP-seq
MIRT847947	hsa-miR-208b	CLIP-seq
MIRT847948	hsa-miR-3135	CLIP-seq
MIRT847949	hsa-miR-3145-3p	CLIP-seq
MIRT847950	hsa-miR-3187-3p	CLIP-seq
MIRT847951	hsa-miR-3198	CLIP-seq
MIRT847952	hsa-miR-3201	CLIP-seq
MIRT847953	hsa-miR-320a	CLIP-seq
MIRT847954	hsa-miR-320b	CLIP-seq
MIRT847955	hsa-miR-320c	CLIP-seq
MIRT847956	hsa-miR-320d	CLIP-seq
MIRT847957	hsa-miR-320e	CLIP-seq
MIRT847958	hsa-miR-3545-3p	CLIP-seq
MIRT847959	hsa-miR-3646	CLIP-seq
MIRT847960	hsa-miR-3647-3p	CLIP-seq
MIRT847961	hsa-miR-3691-5p	CLIP-seq
MIRT847962	hsa-miR-376a	CLIP-seq
MIRT847963	hsa-miR-376b	CLIP-seq
MIRT847964	hsa-miR-3974	CLIP-seq
MIRT847965	hsa-miR-411	CLIP-seq
MIRT847966	hsa-miR-4251	CLIP-seq
MIRT847967	hsa-miR-4252	CLIP-seq
MIRT847968	hsa-miR-4258	CLIP-seq
MIRT847969	hsa-miR-4294	CLIP-seq
MIRT847970	hsa-miR-4303	CLIP-seq
MIRT847971	hsa-miR-4309	CLIP-seq
MIRT847972	hsa-miR-431	CLIP-seq
MIRT847973	hsa-miR-4325	CLIP-seq
MIRT847974	hsa-miR-4329	CLIP-seq
MIRT847975	hsa-miR-4420	CLIP-seq
MIRT847976	hsa-miR-4424	CLIP-seq
MIRT847977	hsa-miR-4428	CLIP-seq
MIRT847978	hsa-miR-4429	CLIP-seq
MIRT847979	hsa-miR-4432	CLIP-seq
MIRT847980	hsa-miR-4435	CLIP-seq
MIRT847981	hsa-miR-4438	CLIP-seq
MIRT847982	hsa-miR-4470	CLIP-seq
MIRT847983	hsa-miR-4534	CLIP-seq
MIRT847984	hsa-miR-4635	CLIP-seq
MIRT847985	hsa-miR-4652-3p	CLIP-seq
MIRT847986	hsa-miR-4670-3p	CLIP-seq
MIRT847987	hsa-miR-4680-5p	CLIP-seq
MIRT847988	hsa-miR-4701-5p	CLIP-seq
MIRT847989	hsa-miR-4704-3p	CLIP-seq
MIRT847990	hsa-miR-4707-3p	CLIP-seq
MIRT847991	hsa-miR-4708-5p	CLIP-seq
MIRT847992	hsa-miR-4717-3p	CLIP-seq
MIRT847993	hsa-miR-4752	CLIP-seq
MIRT847994	hsa-miR-4755-3p	CLIP-seq
MIRT847995	hsa-miR-4770	CLIP-seq
MIRT847996	hsa-miR-4775	CLIP-seq
MIRT847997	hsa-miR-4778-5p	CLIP-seq
MIRT847998	hsa-miR-4781-3p	CLIP-seq
MIRT847999	hsa-miR-4786-3p	CLIP-seq
MIRT848000	hsa-miR-4791	CLIP-seq
MIRT848001	hsa-miR-496	CLIP-seq
MIRT848002	hsa-miR-499-5p	CLIP-seq
MIRT848003	hsa-miR-5095	CLIP-seq
MIRT848004	hsa-miR-539	CLIP-seq
MIRT848005	hsa-miR-544	CLIP-seq
MIRT848006	hsa-miR-548s	CLIP-seq
MIRT848007	hsa-miR-550a	CLIP-seq
MIRT848008	hsa-miR-582-3p	CLIP-seq
MIRT848009	hsa-miR-588	CLIP-seq
MIRT848010	hsa-miR-590-3p	CLIP-seq
MIRT848011	hsa-miR-615-5p	CLIP-seq
MIRT848012	hsa-miR-630	CLIP-seq
MIRT848013	hsa-miR-640	CLIP-seq
MIRT848014	hsa-miR-670	CLIP-seq
MIRT848015	hsa-miR-720	CLIP-seq
MIRT848016	hsa-miR-875-3p	CLIP-seq
MIRT848017	hsa-miR-875-5p	CLIP-seq
MIRT848018	hsa-miR-924	CLIP-seq
MIRT848019	hsa-miR-1179	CLIP-seq
MIRT848020	hsa-miR-125a-5p	CLIP-seq
MIRT848021	hsa-miR-125b	CLIP-seq
MIRT848022	hsa-miR-1262	CLIP-seq
MIRT848023	hsa-miR-147	CLIP-seq
MIRT848024	hsa-miR-219-5p	CLIP-seq
MIRT847948	hsa-miR-3135	CLIP-seq
MIRT848025	hsa-miR-3194-3p	CLIP-seq
MIRT848026	hsa-miR-3674	CLIP-seq
MIRT847962	hsa-miR-376a	CLIP-seq
MIRT847963	hsa-miR-376b	CLIP-seq
MIRT847967	hsa-miR-4252	CLIP-seq
MIRT848027	hsa-miR-4319	CLIP-seq
MIRT848028	hsa-miR-4445	CLIP-seq
MIRT848029	hsa-miR-4477a	CLIP-seq
MIRT848030	hsa-miR-4646-3p	CLIP-seq
MIRT847986	hsa-miR-4670-3p	CLIP-seq
MIRT848031	hsa-miR-4677-3p	CLIP-seq
MIRT848032	hsa-miR-4679	CLIP-seq
MIRT848033	hsa-miR-4701-3p	CLIP-seq
MIRT848034	hsa-miR-4732-3p	CLIP-seq
MIRT848035	hsa-miR-4766-5p	CLIP-seq
MIRT848036	hsa-miR-4782-3p	CLIP-seq
MIRT848037	hsa-miR-508-3p	CLIP-seq
MIRT848007	hsa-miR-550a	CLIP-seq
MIRT848011	hsa-miR-615-5p	CLIP-seq
MIRT848014	hsa-miR-670	CLIP-seq
MIRT848015	hsa-miR-720	CLIP-seq
MIRT847962	hsa-miR-376a	CLIP-seq
MIRT847963	hsa-miR-376b	CLIP-seq
MIRT847962	hsa-miR-376a	CLIP-seq
MIRT847963	hsa-miR-376b	CLIP-seq
MIRT847962	hsa-miR-376a	CLIP-seq
MIRT847963	hsa-miR-376b	CLIP-seq
MIRT847962	hsa-miR-376a	CLIP-seq
MIRT847963	hsa-miR-376b	CLIP-seq
MIRT847962	hsa-miR-376a	CLIP-seq
MIRT847963	hsa-miR-376b	CLIP-seq
MIRT1951516	hsa-miR-106a	CLIP-seq
MIRT1951517	hsa-miR-106b	CLIP-seq
MIRT1951518	hsa-miR-1297	CLIP-seq
MIRT1951519	hsa-miR-150	CLIP-seq
MIRT1951520	hsa-miR-17	CLIP-seq
MIRT1951521	hsa-miR-1915	CLIP-seq
MIRT1951522	hsa-miR-20a	CLIP-seq
MIRT1951523	hsa-miR-20b	CLIP-seq
MIRT848024	hsa-miR-219-5p	CLIP-seq
MIRT1951524	hsa-miR-26a	CLIP-seq
MIRT1951525	hsa-miR-26b	CLIP-seq
MIRT1951526	hsa-miR-302a	CLIP-seq
MIRT1951527	hsa-miR-302b	CLIP-seq
MIRT1951528	hsa-miR-302c	CLIP-seq
MIRT1951529	hsa-miR-302d	CLIP-seq
MIRT1951530	hsa-miR-302e	CLIP-seq
MIRT1951531	hsa-miR-3170	CLIP-seq
MIRT1951532	hsa-miR-3180-5p	CLIP-seq
MIRT1951533	hsa-miR-372	CLIP-seq
MIRT1951534	hsa-miR-373	CLIP-seq
MIRT847968	hsa-miR-4258	CLIP-seq
MIRT1951535	hsa-miR-4279	CLIP-seq
MIRT847981	hsa-miR-4438	CLIP-seq
MIRT1951536	hsa-miR-4465	CLIP-seq
MIRT1951537	hsa-miR-4529-5p	CLIP-seq
MIRT1951538	hsa-miR-4695-3p	CLIP-seq
MIRT847990	hsa-miR-4707-3p	CLIP-seq
MIRT1951539	hsa-miR-4726-3p	CLIP-seq
MIRT1951540	hsa-miR-4731-5p	CLIP-seq
MIRT1951541	hsa-miR-4772-3p	CLIP-seq
MIRT1951542	hsa-miR-4777-5p	CLIP-seq
MIRT848036	hsa-miR-4782-3p	CLIP-seq
MIRT848003	hsa-miR-5095	CLIP-seq
MIRT1951543	hsa-miR-512-3p	CLIP-seq
MIRT1951544	hsa-miR-519d	CLIP-seq
MIRT1951545	hsa-miR-520a-3p	CLIP-seq
MIRT1951546	hsa-miR-520b	CLIP-seq
MIRT1951547	hsa-miR-520c-3p	CLIP-seq
MIRT1951548	hsa-miR-520d-3p	CLIP-seq
MIRT1951549	hsa-miR-520d-5p	CLIP-seq
MIRT1951550	hsa-miR-520e	CLIP-seq
MIRT1951551	hsa-miR-520g	CLIP-seq
MIRT1951552	hsa-miR-520h	CLIP-seq
MIRT1951553	hsa-miR-524-5p	CLIP-seq
MIRT1951554	hsa-miR-760	CLIP-seq
MIRT1951555	hsa-miR-93	CLIP-seq
MIRT1951518	hsa-miR-1297	CLIP-seq
MIRT1951519	hsa-miR-150	CLIP-seq
MIRT1951521	hsa-miR-1915	CLIP-seq
MIRT1951524	hsa-miR-26a	CLIP-seq
MIRT1951525	hsa-miR-26b	CLIP-seq
MIRT2189459	hsa-miR-3149	CLIP-seq
MIRT2189460	hsa-miR-3152-5p	CLIP-seq
MIRT2189461	hsa-miR-3929	CLIP-seq
MIRT847965	hsa-miR-411	CLIP-seq
MIRT1951535	hsa-miR-4279	CLIP-seq
MIRT2189462	hsa-miR-4419b	CLIP-seq
MIRT1951536	hsa-miR-4465	CLIP-seq
MIRT2189463	hsa-miR-4478	CLIP-seq
MIRT1951538	hsa-miR-4695-3p	CLIP-seq
MIRT1951539	hsa-miR-4726-3p	CLIP-seq
MIRT1951541	hsa-miR-4772-3p	CLIP-seq
MIRT847998	hsa-miR-4781-3p	CLIP-seq
MIRT2189464	hsa-miR-502-5p	CLIP-seq
MIRT2464989	hsa-miR-4716-5p	CLIP-seq
MIRT1951542	hsa-miR-4777-5p	CLIP-seq
MIRT2464990	hsa-miR-518d-5p	CLIP-seq
MIRT2464991	hsa-miR-519b-5p	CLIP-seq
MIRT2464992	hsa-miR-519c-5p	CLIP-seq
MIRT2464993	hsa-miR-520c-5p	CLIP-seq
MIRT2464994	hsa-miR-526a	CLIP-seq
MIRT2493140	hsa-miR-1234	CLIP-seq
MIRT847944	hsa-miR-129-5p	CLIP-seq
MIRT1951519	hsa-miR-150	CLIP-seq
MIRT1951521	hsa-miR-1915	CLIP-seq
MIRT2189459	hsa-miR-3149	CLIP-seq
MIRT847968	hsa-miR-4258	CLIP-seq
MIRT847977	hsa-miR-4428	CLIP-seq
MIRT1951538	hsa-miR-4695-3p	CLIP-seq
MIRT847990	hsa-miR-4707-3p	CLIP-seq
MIRT1951539	hsa-miR-4726-3p	CLIP-seq
MIRT1951541	hsa-miR-4772-3p	CLIP-seq
MIRT847996	hsa-miR-4775	CLIP-seq
MIRT1951551	hsa-miR-520g	CLIP-seq
MIRT1951552	hsa-miR-520h	CLIP-seq
MIRT848010	hsa-miR-590-3p	CLIP-seq
MIRT848013	hsa-miR-640	CLIP-seq
MIRT848017	hsa-miR-875-5p	CLIP-seq
MIRT2676906	hsa-miR-122	CLIP-seq
MIRT2676907	hsa-miR-1287	CLIP-seq
MIRT2676908	hsa-miR-30a	CLIP-seq
MIRT2676909	hsa-miR-30b	CLIP-seq
MIRT2676910	hsa-miR-30c	CLIP-seq
MIRT2676911	hsa-miR-30d	CLIP-seq
MIRT2676912	hsa-miR-30e	CLIP-seq
MIRT847968	hsa-miR-4258	CLIP-seq
MIRT847977	hsa-miR-4428	CLIP-seq
MIRT2676913	hsa-miR-4495	CLIP-seq
MIRT1951538	hsa-miR-4695-3p	CLIP-seq
MIRT847990	hsa-miR-4707-3p	CLIP-seq
MIRT2676914	hsa-miR-4764-5p	CLIP-seq
MIRT1951541	hsa-miR-4772-3p	CLIP-seq
MIRT2676915	hsa-miR-4773	CLIP-seq
MIRT848017	hsa-miR-875-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 28514442, 31515488, 32296183, 33961781, 36882524
GO:0005886	Component	Plasma membrane	IEA
GO:0016020	Component	Membrane	IEA
GO:0051726	Process	Regulation of cell cycle	IMP	36882524
GO:0071944	Component	Cell periphery	IDA	38517886

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q8IY42
• Protein name: PDCD10 and GCKIII kinases-associated protein 1
• Protein function: Acts as a tumor suppressor (PubMed:36882524, PubMed:38517886). Acts as a tumor suppressor for colorectal cancer cell proliferation by targeting KEAP1/USP17/ELK1/CDK6 axis (PubMed:36882524). {ECO:0000269|PubMed:36882524, ECO:0000269|PubMed:385178
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15770	DUF4699	9 → 314	Domain of unknown function (DUF4699)	Family

• Sequence:

  MGCRCCKIIQSYLFDPVQVPSPGYVNEVNSCKLDEDDTDKLKGKWSSEVLVQKNDPQRQG
  SKKTESSSRTADPWEPCWPHQGPLPQGDAGGEHHACGVNGIGPAATPQPTGNSSPTQDDR
  GSWASTANTVPPTQPFLEGGGTRKQDCVLLASEGTQVMRNGDSRAPSEAESFALEVQDHV
  FQIPAPDYLQHWGPAGDNVDHNEKDCVFKNHTEDESLEGIQPPVGEHGLNTPFSVRRSWD
  SLNEDVETEVLSICFNEKGPVHAMPVVDSGNRQEDTHGSDGDGDGEIVDEDAAVAEALAA
  LEAATAGEDLDETD

• Sequence length: 314