VPS53 (VPS53 subunit of GARP complex)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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55275 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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VPS53 subunit of GARP complex |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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VPS53 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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HCCS1, PCH2E, hVps53L, pp13624 |
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Chromosome
Chromosome number
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17 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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17p13.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a protein with sequence similarity to the yeast Vps53p protein. Vps53p is involved in retrograde vesicle trafficking in late Golgi. [provided by RefSeq, Jul 2008] |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q5VIR6 | ||||||||||
| Protein name | Vacuolar protein sorting-associated protein 53 homolog | ||||||||||
| Protein function | Acts as a component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors bet | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 832 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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